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21. 发明申请

US20120308449A1 BIOCHIP 审中-公开
公开(公告)号：US20120308449A1
公开(公告)日：2012-12-06
申请号：US13335039
申请日：2011-12-22
申请人： Jeong Suong YANG , Bo Sung Ku
发明人： Jeong Suong YANG , Bo Sung Ku
IPC分类号： B01L3/00
CPC分类号： G01N33/6803 , B01L3/5085 , B01L3/5088 , B01L3/563 , B01L2200/141 , B01L2300/069 , B01L2300/0819 , B01L2300/165 , C12M23/12 , C12M23/20 , C12M23/38 , G01N33/54393
摘要： There is provided a biochip including: a hydrophilic first substrate including a plurality of micro wells formed therein at predetermined intervals; a hydrophobic barrier layer formed on a surface of the hydrophilic first substrate; and a hydrophobic second substrate including biomaterials formed thereon, the biomaterials being inserted into the micro wells by joining the hydrophilic first substrate and the hydrophobic second substrate.
摘要翻译：提供了一种生物芯片，其包括：亲水性第一基板，其包括以预定间隔在其中形成的多个微孔; 形成在所述亲水性第一基板的表面上的疏水性阻隔层; 以及包含在其上形成的生物材料的疏水性第二基底，所述生物材料通过接合亲水性第一基底和疏水性第二基底而插入到微孔中。

22. 发明授权

US08264245B2 Device and system for measuring properties of cells and method of measuring properties of cells using the same 有权
标题翻译：用于测量细胞性质的装置和系统以及使用其测量细胞性质的方法
公开(公告)号：US08264245B2
公开(公告)日：2012-09-11
申请号：US12544098
申请日：2009-08-19
申请人： Bo Sung Ku , Tae Yoon Kim , Young-Ho Cho , Young Soo Oh , Sung Koo Kang , Sang Jin Kim
发明人： Bo Sung Ku , Tae Yoon Kim , Young-Ho Cho , Young Soo Oh , Sung Koo Kang , Sang Jin Kim
IPC分类号： G01R27/08
CPC分类号： G01N33/48735
摘要： According to a device and system for measuring the properties of cells, there is an advantage in that, since a cell accommodation unit having a volume is provided, the properties of three-dimensional cells can be measured. Further, the present invention is advantageous in that it enables passive measurement of multiple properties which passively measures the electrical, mechanical and/or optical properties of cells, and active measurement of multiple properties which actively applies electrical, mechanical and optical types of stimulation to cells and measures their electrical, mechanical and/or optical reactions, thus measuring the multiple properties of cells with high reliability.
摘要翻译：根据用于测量电池性质的装置和系统，其优点在于，由于提供具有体积的电池容纳单元，因此可以测量三维电池的性质。此外，本发明的优点在于其能够被动测量被动测量细胞的电，机械和/或光学性质的多种性质，以及主动测量多种性质，其主动地将电，机械和光学类型的刺激应用于细胞并测量其电，机械和/或光学反应，从而以高可靠性测量电池的多重性能。

23. 发明申请

US20110269645A1 Cell chip, method of manufacturing the same and device for manufacturing cell chip 审中-公开
标题翻译：电池芯片，制造方法和芯片制造装置
公开(公告)号：US20110269645A1
公开(公告)日：2011-11-03
申请号：US12923096
申请日：2010-09-01
申请人： Se Hoon Jeong , Sang Jin Kim , Bo Sung Ku
发明人： Se Hoon Jeong , Sang Jin Kim , Bo Sung Ku
IPC分类号： C40B40/02 , C40B60/08 , C40B50/06 , C40B60/14
CPC分类号： C40B60/14 , B01J19/0046 , B01J2219/00378 , B01J2219/00533 , B01J2219/00619 , B01J2219/00637 , B01J2219/00743
摘要： Provided is a cell chip, a method of manufacturing the same, and a device for manufacturing the same. The cell chip includes a substrate on which a plurality of cell fixing materials having a predetermined area are arranged, a plurality of single cells fixed by the plurality of cell fixing materials, respectively, and a plurality of cell scattering materials formed of a porous material and provided in the form of droplets combined with the plurality of cell fixing materials and surrounding the single cells, respectively. The device for manufacturing the cell chip includes a first inkjet head discharging a cell fixing material having a predetermined area onto a substrate, and a second inkjet head including an internal channel having one or more curved portions, and discharging a plurality of cells, contained in a cell scattering material passing through the internal channel, individually to the cell fixing material.
摘要翻译：提供了一种电池芯片及其制造方法及其制造装置。电池芯片包括其上布置有多个具有预定面积的电池固定材料的基板，分别由多个电池固定材料固定的多个单电池单元和由多孔材料形成的多个电池散射材料和提供以与多个电池固定材料组合的液滴的形式并且分别围绕单个电池。用于制造电池芯片的装置包括将具有预定区域的电池固定材料放电到基板上的第一喷墨头和包括具有一个或多个弯曲部分的内部通道的第二喷墨头，通过内部通道的细胞散射材料单独地连接到细胞固定材料。

24. 发明申请

US20100321450A1 Droplet Receiver and Method Of Receiving Droplets 有权
标题翻译：液滴接收器和接收水滴的方法
公开(公告)号：US20100321450A1
公开(公告)日：2010-12-23
申请号：US12541054
申请日：2009-08-13
申请人： Sang Jin Kim , Tae Yoon Kim , Young-Ho Cho , Young Soo Oh , Bo Sung Ku , Sung Koo Kang
发明人： Sang Jin Kim , Tae Yoon Kim , Young-Ho Cho , Young Soo Oh , Bo Sung Ku , Sung Koo Kang
IPC分类号： B41J2/07
CPC分类号： B01L3/50853 , B01L3/0268 , B01L3/502715 , B01L2200/0642 , B01L2200/0673 , B01L2200/141 , B01L2200/142 , B01L2300/12
摘要： Disclosed herein is a droplet receiver. The droplet receiver includes an internal space formed such that its sectional area is reduced towards an input part, thus preventing the rebounding of droplets which enter a droplet receiving part, and includes an intercepting fluid layer so as to isolate the received droplets from the outside, thus preventing droplets received in the droplet receiving part from being contaminated and volatilizing.
摘要翻译：这里公开了一种液滴接收器。液滴接收器包括形成为使得其截面积朝向输入部分减小的内部空间，从而防止进入液滴接收部分的液滴的反弹，并且包括拦截流体层，以将接收的液滴与外部隔离，从而防止容纳在液滴接收部中的液滴被污染和挥发。

25. 发明授权

US09151745B2 Chip for inspecting toxicity and efficacy 有权
标题翻译：用于检查毒性和功效的芯片
公开(公告)号：US09151745B2
公开(公告)日：2015-10-06
申请号：US12760131
申请日：2010-04-14
申请人： Sang Jin Kim , Jeong Suong Yang , Bo Sung Ku
发明人： Sang Jin Kim , Jeong Suong Yang , Bo Sung Ku
IPC分类号： C12M1/34 , G01N33/53 , G01N33/543 , B01J19/00
CPC分类号： G01N33/5302 , B01J19/0046 , B01J2219/00722 , G01N33/54373
摘要： Disclosed herein is a chip for inspecting toxicity and efficacy, including: a first substrate including fitting holes formed at corners thereof; and a second substrate including gap forming members formed at corners thereof corresponding to the fitting holes to form a gap between the first substrate and the second substrate, and protrusions formed on the gap forming members corresponding to the fitting holes and fitted in the fitting holes. The chip for inspecting toxicity and efficacy is advantageous in that alignment of the chip can be easily performed, in that problems with the emission of fluorescence or the penetration of measuring light in the chip can be solved, and in that the cost of producing the chip can be reduced.
摘要翻译：本文公开了一种用于检查毒性和功效的芯片，包括：第一基板，包括在其角部处形成的装配孔; 以及第二基板，其包括形成在其对应于所述装配孔的角部处的间隙形成部件，以在所述第一基板和所述第二基板之间形成间隙，以及形成在所述间隙形成部件上的对应于所述装配孔并且嵌合在所述装配孔中的突起。用于检查毒性和功效的芯片的优点在于可以容易地进行芯片的对准，因为可以解决荧光发射或测量光在芯片中的穿透的问题，并且生产芯片的成本可以减少

26. 发明授权

US08657412B2 Micro-ejection device 失效
标题翻译：微型喷射装置
公开(公告)号：US08657412B2
公开(公告)日：2014-02-25
申请号：US13358345
申请日：2012-01-25
申请人： Sang Jin Kim , Bo Sung Ku
发明人： Sang Jin Kim , Bo Sung Ku
IPC分类号： B41J2/14
CPC分类号： B01L9/547 , B01L3/0248 , B01L2200/023 , B01L2300/123
摘要： There is provided a micro-ejection device including: an ejector ejecting a fluid; and a body having an installation space in which the ejector is installed, wherein the installation space is provided with a guide unit inducing a line-contact or a point-contact between the ejector and the body.
摘要翻译：提供一种微型喷射装置，包括：喷射器喷射流体; 以及具有其中安装有喷射器的安装空间的主体，其中所述安装空间设置有引导所述喷射器和所述主体之间的线接触或点接触的引导单元。

27. 发明申请

US20130102502A1 BIO-CHIP 审中-公开
标题翻译：生物芯片
公开(公告)号：US20130102502A1
公开(公告)日：2013-04-25
申请号：US13358252
申请日：2012-01-25
申请人： Jeong Suong YANG , Bo Sung Ku
发明人： Jeong Suong YANG , Bo Sung Ku
IPC分类号： C40B60/14
CPC分类号： B01J19/0046 , B01J2219/00509 , B01J2219/00662 , B01J2219/00722 , B01J2219/00725 , B01J2219/0074 , C40B20/02 , C40B60/12
摘要： There is provided a bio-chip including a first substrate including a first recess formed in a first end surface thereof; and a second substrate including a first coupling pillar inserted into the first recess and a second coupling pillar in contact with a second end surface opposed to the first end surface.
摘要翻译：提供了一种生物芯片，其包括：第一基板，包括形成在其第一端面中的第一凹部; 以及第二基板，其包括插入到所述第一凹部中的第一联接柱和与所述第一端面相对的第二端面接触的第二联接柱。

28. 发明申请

US20130083127A1 MICRO-EJECTION DEVICE 失效
标题翻译：微型喷射装置
公开(公告)号：US20130083127A1
公开(公告)日：2013-04-04
申请号：US13358345
申请日：2012-01-25
申请人： Sang Jin KIM , Bo Sung Ku
发明人： Sang Jin KIM , Bo Sung Ku
IPC分类号： B41J2/14
CPC分类号： B01L9/547 , B01L3/0248 , B01L2200/023 , B01L2300/123
摘要： There is provided a micro-ejection device including: an ejector ejecting a fluid; and a body having an installation space in which the ejector is installed, wherein the installation space is provided with a guide unit inducing a line-contact or a point-contact between the ejector and the body.
摘要翻译：提供一种微型喷射装置，包括：喷射器喷射流体; 以及具有其中安装有喷射器的安装空间的主体，其中所述安装空间设置有引导所述喷射器和所述主体之间的线接触或点接触的引导单元。

29. 发明申请

US20110318229A1 DROPLET DISCHARGING APPARATUS FOR CELL COUNTING 审中-公开
标题翻译：用于细胞计数的滴液放电装置
公开(公告)号：US20110318229A1
公开(公告)日：2011-12-29
申请号：US12902036
申请日：2010-10-11
申请人： Se Hoon Jeong , Sang Youl Jeon , Bo Sung Ku
发明人： Se Hoon Jeong , Sang Youl Jeon , Bo Sung Ku
IPC分类号： G01N21/55
CPC分类号： G01N15/147 , G01N2015/1481 , G01N2015/1486
摘要： There is provided a droplet discharging apparatus for cell counting that includes: a droplet flowing unit into which a droplet is injected; a pumping unit allowing the injected droplet to flow or to stop flowing; a droplet discharging unit discharging the droplet to a target unit or a receiving unit; a detection unit installed on a droplet discharging route, and irradiating light to the droplet and receiving light reflected on the droplet to generate a light receiving signal; and a control unit performing a control operation by counting the number of cells by receiving the light receiving signal from the detection unit and determining whether or not the cell is present on the basis of the level of the received light receiving signal. Therefore, it is possible to discharge the droplet by accurately counting the number of cells in the droplet.
摘要翻译：提供了一种用于细胞计数的液滴喷射装置，其包括：液滴流入单元，其中注入液滴; 泵送单元，允许喷射的液滴流动或停止流动; 液滴喷射单元，其将液滴喷射到目标单元或接收单元; 安装在液滴喷射路径上的检测单元，并且向所述液滴照射光并接收在所述液滴上反射的光以产生光接收信号; 以及控制单元，通过从所述检测单元接收光接收信号来对所述单元数进行计数，并基于所接收的光接收信号的电平确定所述单元是否存在来执行控制操作。因此，可以通过精确地计数液滴中的细胞数来排出液滴。

30. 发明申请

US20110294703A1 Stamping Apparatus For Biochips and Method For Operation Thereof 有权
标题翻译：生物芯片冲压装置及其操作方法
公开(公告)号：US20110294703A1
公开(公告)日：2011-12-01
申请号：US12848888
申请日：2010-08-02
申请人： Sang Youl JEON , Sang Jin Kim , Jeong Suong Yang , Bo Sung Ku
发明人： Sang Youl JEON , Sang Jin Kim , Jeong Suong Yang , Bo Sung Ku
IPC分类号： C40B50/00 , C40B60/14
CPC分类号： B01J19/0046 , B01J2219/00382 , B01J2219/00385 , B01J2219/00529 , B01J2219/00533 , B01J2219/00722 , C40B60/14
摘要： Disclosed herein is a stamping apparatus for biochips and a method of operating the stamping apparatus. The apparatus includes a table, a first chip table, a second chip table, a stamping unit and a control unit. The first chip table is provided on the table. A first biochip is seated onto the first ship table. A second biochip is seated onto the second chip table. The stamping unit is mounted to the table and operates the second chip table such that a surface of a junction of the second biochip seated on the second chip table is joined to a surface of a junction of the first biochip seated on the first chip table. The control unit controls operation of the first chip table or the second chip table.
摘要翻译：本文公开了一种用于生物芯片的冲压装置和操作冲压装置的方法。该装置包括一台，第一芯片台，第二芯片台，冲压单元和控制单元。第一个芯片表在桌子上提供。第一个生物芯片坐在第一个船上。第二个生物芯片就座在第二个芯片台上。冲压单元安装在工作台上并操作第二芯片台，使得位于第二芯片工作台上的第二生物芯片的接合表面与位于第一芯片工作台上的第一生物芯片的接合表面接合。控制单元控制第一芯片表或第二芯片表的操作。

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