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21. 发明授权

US5626626A Implantable medical apparatus with magnifying header 失效
公开(公告)号：US5626626A
公开(公告)日：1997-05-06
申请号：US443127
申请日：1995-05-17
申请人： Dean F. Carson
发明人： Dean F. Carson
IPC分类号： A61N1/375 , A61N1/36
CPC分类号： A61N1/3752
摘要： An implantable medical apparatus operable in conjunction with an attachable lead, and having a housing containing an electronic component, with a header connected to the housing and defining a cavity. A connector element is positioned within the cavity and is operably connected to the electronic component. A lens is connected to the header, such that the connector element may be viewed through the lens to facilitate confirmation of proper connection of a lead to the connector. The header may be transparent, and the lens either formed as part of the header, or detachable therefrom.

22. 发明授权

US6078839A Abrasion resistant implantable lead insulation protector 有权
标题翻译：耐磨可植入铅绝缘保护器
公开(公告)号：US6078839A
公开(公告)日：2000-06-20
申请号：US208721
申请日：1998-12-09
申请人： Dean F. Carson
发明人： Dean F. Carson
IPC分类号： A61N1/05
CPC分类号： A61N1/056
摘要： An abrasion resistant implantable lead is described including a protector for preventing abrasion to lead insulation. A helix-shaped protector can be placed around portions of the implantable lead to prevent frictional contact between the lead and the metallic casing of an implantable medical device, known as a pulse generator. The protector can have a cross-section and end-view of various shapes. The protector can be made of a flexible, elastomeric biocompatible material and can be coated by a hydrophilic surface to minimize the coefficient of friction between the protector and the casing of the pulse generator. The protector can have an inner cross-sectional diameter equal to or less than an outer cross-sectional diameter of the lead insulation, ensuring a snug fit. A toolkit for selecting, sizing and positioning the proper protector is described.
摘要翻译：描述了耐磨可植入引线，其包括用于防止对绝缘的磨损的保护器。螺旋形保护器可以放置在可植入引线的部分周围，以防止被称为脉冲发生器的可植入医疗装置的引线和金属外壳之间的摩擦接触。保护器可以具有各种形状的横截面和端视图。保护器可以由柔性的弹性体生物相容材料制成，并且可以通过亲水表面涂覆，以使脉冲发生器的保护器和外壳之间的摩擦系数最小化。保护器可以具有等于或小于导线绝缘体的外横截面直径的内截面直径，确保贴合。描述了用于选择，调整和定位适当保护器的工具包。

23. 发明授权

US5902329A Explantable lead 失效
标题翻译：可引导铅
公开(公告)号：US5902329A
公开(公告)日：1999-05-11
申请号：US970492
申请日：1997-11-14
申请人： Drew A. Hoffmann , Dean F. Carson
发明人： Drew A. Hoffmann , Dean F. Carson
IPC分类号： A61K47/48 , A61L31/10 , A61L31/14 , A61N1/05
CPC分类号： A61L31/145 , A61K47/48992 , A61L31/10
摘要： An extractable lead and method for chronic blood contacting use. The new lead contains a hydrogel coating having a thickness increase greater than 10% when hydrated. A thick coating is used to provide a shear layer so that the coating tears during extraction, either at the coating/lead interface, between layers of the coating itself, or at the coating/tissue interface. Furthermore, because of the flexibility of such a thick coating, contracture of any fibrous capsule that may have formed is not a problem during extraction, since instead of contracting onto the lead, it contracts onto the flexible coating which can be extracted out of the tight capsule.
摘要翻译：用于慢性血液接触使用的可提取铅和方法。新的铅含有当水合时厚度增加大于10％的水凝胶涂层。使用厚涂层来提供剪切层，使得涂层在涂层/引线界面处，在涂层本身的层之间或在涂层/组织界面处提取期间撕裂。此外，由于这种厚涂层的灵活性，可能形成的任何纤维胶囊的挛缩在提取过程中不是问题，因为它不是收缩到铅上，而是收缩到柔性涂层上，可以从紧的胶囊。

24. 发明授权

US5720631A Lead lumen sealing device 失效
标题翻译：铅流明密封装置
公开(公告)号：US5720631A
公开(公告)日：1998-02-24
申请号：US850882
申请日：1997-05-02
申请人： Dean F. Carson , Richard J. Gable
发明人： Dean F. Carson , Richard J. Gable
IPC分类号： A61N1/05 , A61N1/375 , H01R4/36 , H01R13/24 , H01R13/52 , H01R17/18
CPC分类号： A61N1/056 , A61N1/3752 , H01R13/5224 , H01R13/24 , H01R13/5205 , H01R4/36 , Y10S439/909 , Y10S439/948
摘要： A lead sealing device that resides within the connector cavity of a pacemaker or defibrillator intended to prevent fluid intrusion by automatically sealing the lead lumen when the lead connector is inserted. The sealing mechanism may be in the form of a silicone disk located at the base of the space defined by the connector cavity in which the lead is inserted to make electrical and physical contact. It may be fixedly located at the bottom of the connector cavity, or may be a movable plug located within the connector cavity at a location other than the bottom of the cavity, such as adjacent to the connector block. In that case, the pin will make contact with the movable plug immediately after passing through the connector block, and will remain in contact with and seal the lead lumen while the pin and plug are further advanced to bring the pin into its final location to make electrical contact with the connector contact.
摘要翻译：引线密封装置位于起搏器或除颤器的连接器腔内，旨在通过在插入导线连接器时自动密封引流管腔来防止流体侵入。密封机构可以是位于由连接器腔限定的空间的底部的硅树脂的形式，其中铅插入其中以进行电和物理接触。它可以固定地位于连接器腔的底部，或者可以是位于连接器空腔内的除了腔的底部之外的位置的可移动的插塞，例如邻近连接器块。在这种情况下，引脚将在通过连接器块之后立即与可动插头接触，并且在引脚和插头进一步前进以使引脚进入其最终位置时将保持接触并密封引线管腔与连接器触点电接触。

25. 发明授权

US5545206A Low profile lead with automatic tine activation 失效
标题翻译：薄型导线，自动激光
公开(公告)号：US5545206A
公开(公告)日：1996-08-13
申请号：US362035
申请日：1994-12-22
申请人： Dean F. Carson
发明人： Dean F. Carson
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N1/0565
摘要： A transvenous lead system for cardiac stimulation with a pacemaker or implantable defibrillator having automatic activation of a passive fixation system. The lead includes an insulative lead body such as silicone rubber and has a proximal end with a connector for coupling the lead to the pacemaker or defibrillator. At least one conductor extends through the lead body for connection to a lead electrode. The lead further includes a plurality of flexible tines. In a first position, the tines are folded back along the lead body and exhibit a minimal profile. A hydrophilic material such as a hydrogel is disposed on the under side of each tine either as part of the tine or between the tine and the lead body. Upon exposure to body fluids when the lead is implanted, the hydrogel absorbs liquid and expands. This expansion forces the tines into a second, deployed position where the tines can engage trabeculae of the heart chambers to anchor the lead in place.
摘要翻译：一种用起搏器或植入式除颤器进行心脏刺激的经静脉引导系统，其具有被动固定系统的自动激活。引线包括诸如硅橡胶的绝缘引线体，并且具有近端，其具有用于将引线耦合到起搏器或除颤器的连接器。至少一个导体延伸穿过引线主体以连接到引线电极。引线还包括多个柔性尖齿。在第一位置，尖齿沿引线体折回并且呈现最小的轮廓。亲水材料如水凝胶被设置在每个齿的下侧，或者作为齿的一部分，或者在齿与引线体之间。当植入铅时暴露于体液时，水凝胶吸收液体并膨胀。这种扩张迫使齿进入第二个部署位置，在这个位置，尖齿可以接合心室的小梁，以将导线固定到位。

26. 发明授权

US4849256A Process for plasticizing polyvinyl alcohol resin 失效
标题翻译：聚乙烯醇树脂增塑方法
公开(公告)号：US4849256A
公开(公告)日：1989-07-18
申请号：US166863
申请日：1988-03-11
申请人： Garry F. Newman , Dean F. Carson , Steve B. Cherry
发明人： Garry F. Newman , Dean F. Carson , Steve B. Cherry
IPC分类号： C08J3/12 , C08J3/18 , C08L29/04
CPC分类号： C08J3/124 , C08J3/18 , C08J2329/04 , Y10T428/254
摘要： An improved method for the production of a plasticizer-containing dry flowable polyvinyl alcohol (PVA) resin blend capable of thermoplastic processing. The method provides for the incorporation of plasticizers in intimate contact with the PVA resin without heating, cooling, or extended drying steps. Specifically, PVA resin granules having an appropriately small particle size distribution are spray-coated with a liquid plasticizer medium, and then mixed with a dry, fine powder coating medium to produce a flowable, dry plasticized PVA blend. Additional components, such as antioxidants, dyes, and antiblocking agents, may also be incorporated into the finished product.

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