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21. 发明申请

US20070093460A1 Methods of using selective 11beta-HSD inhibitors to treat gluocorticoid associated states 审中-公开
标题翻译：使用选择性11beta-HSD抑制剂治疗糖皮质激素相关状态的方法
公开(公告)号：US20070093460A1
公开(公告)日：2007-04-26
申请号：US11509181
申请日：2006-08-24
申请人： David Morris , Andrew Brem
发明人： David Morris , Andrew Brem
IPC分类号： A61K31/57 , A61K31/573
CPC分类号： A61K31/573 , A61K31/57 , A61K45/06 , A61K2300/00
摘要： Methods for treating glucocorticoid associated states using selective 11β-HSD1-dehydrogenase, 11β-HSD1-reductase and 11β-HSD2 dehydrogenase modulating compounds are described.
摘要翻译：描述了使用选择性11beta-HSD1-脱氢酶，11beta-HSD1-还原酶和11beta-HSD2脱氢酶调节化合物治疗糖皮质激素相关状态的方法。

22. 发明申请

US20060177861A1 Novel compositions and methods in cancer associated with altered expression of MCM3AP 审中-公开
标题翻译：与MCM3AP表达改变相关的癌症新型组合物和方法
公开(公告)号：US20060177861A1
公开(公告)日：2006-08-10
申请号：US11357638
申请日：2006-02-17
申请人： David Morris , Eric Engelhard
发明人： David Morris , Eric Engelhard
IPC分类号： C12Q1/68
CPC分类号： G01N33/574 , C07K14/47 , C12N9/1029 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5011 , G01N2500/00
摘要： The present invention relates to novel sequences for use in diagnosis and treatment of carcinomas, especially breast cancers. In addition, the present invention describes the use of novel compositions for use in screening methods. The invention provides methods and compositioins associated with altered expression of MCM3AP.
摘要翻译：本发明涉及用于诊断和治疗癌症，特别是乳腺癌的新型序列。此外，本发明描述了用于筛选方法的新型组合物的用途。本发明提供了与改变的MCM3AP表达相关的方法和组合物。

23. 发明申请

US20060142757A1 Apparatus and method for tissue resection 审中-公开
标题翻译：组织切除术的装置和方法
公开(公告)号：US20060142757A1
公开(公告)日：2006-06-29
申请号：US11335092
申请日：2006-01-18
申请人： Steven Daniel , David Morris
发明人： Steven Daniel , David Morris
IPC分类号： A61B18/14
CPC分类号： A61B18/1477 , A61B90/11 , A61B2018/0016 , A61B2018/00577 , A61B2018/1425 , A61B2018/143 , A61B2018/1475
摘要： A tissue ablation system is described that generates a uniform avascular plane of coagulated tissue to aid in the bloodless or near-bloodless resection of various biological tissues from a variety of organs. The tissue ablation system includes an energy director guide and two or more sets of bipolar energy directors. The energy director guide includes a series of channels that configure the energy directors to provide approximately uniform power distribution or current density through a target tissue volume or plane. The spacing among the channels of the energy director guide varies according to the total number of energy directors received in the energy director guide so that relative spacing among the center-most channels is largest and relative spacing among the end-most channels is smallest. The energy director guide secures a selected position of each of the energy directors in the target tissue volume.
摘要翻译：描述了组织消融系统，其产生凝固组织的均匀的无血管平面，以帮助来自各种器官的各种生物组织的无血或近无血的切除。组织消融系统包括能量导向器引导件和两组或多组双极能量引导器。能量导向器引导件包括一系列通道，其配置能量引导器以通过目标组织体积或平面提供近似均匀的功率分布或电流密度。能量导向器引导件的通道之间的间隔根据能量导向器引导器中接收到的能量引导器的总数而变化，使得最中心的通道之间的相对间隔最大，并且最终通道之间的相对间隔最小。能量导向器引导件将每个能量引导器的选定位置固定在目标组织体积中。

24. 发明申请

US20050210739A1 Blends of synthetic distillate and biodiesel for low nitrogen oxide emissions from diesel engines 审中-公开
标题翻译：合成馏分和生物柴油的混合物用于柴油发动机的低氮氧化物排放
公开(公告)号：US20050210739A1
公开(公告)日：2005-09-29
申请号：US11076178
申请日：2005-03-09
申请人： Etop Esen , Andre Boehman , David Morris
发明人： Etop Esen , Andre Boehman , David Morris
IPC分类号： C10L1/02 , C10L1/14 , C10L1/16 , C10L1/18 , C10L1/19 , C10L10/02
CPC分类号： C10L1/19 , C10L1/026 , C10L1/14 , C10L1/1616 , C10L1/18 , C10L1/1802 , C10L1/1826 , C10L1/191 , C10L10/02 , Y02E50/13
摘要： This invention shows how to make and use a biodiesel-based fuel in diesel engines without incurring the NOx penalty. Embodiments primarily relate to an optimum range of bulk modulus of compressibility for biodiesel blends, which results in generating “NOx neutral” biodiesel blends or to formulate biodiesel blends with lower NOx emissions than conventional petroleum diesel fuel. These biodiesel blends preferably comprise synthetic paraffinic middle distillate derived from a hydrocarbon synthesis to generate synthetic environmentally-friendly diesel fuels.
摘要翻译：本发明示出了如何在柴油发动机中制造和使用基于生物柴油的燃料，而不会引起NO×××罚分。实施方案主要涉及生物柴油共混物的压缩性体积模量的最佳范围，其导致产生“中性”中性生物柴油混合物或配制具有比常规石油柴油燃料更低的NOx排放的生物柴油混合物。这些生物柴油混合物优选包含衍生自烃合成的合成链烷烃中间馏分，以产生合成的环保柴油。

25. 发明申请

US20050137662A1 Tissue surface treatment apparatus and method 失效
标题翻译：组织表面处理装置及方法
公开(公告)号：US20050137662A1
公开(公告)日：2005-06-23
申请号：US11034435
申请日：2005-01-11
申请人： David Morris , Steven Daniel , Daniel Balbierz
发明人： David Morris , Steven Daniel , Daniel Balbierz
IPC分类号： A61B18/14 , A61F2/00
CPC分类号： A61M25/1002 , A61B18/1477 , A61B2018/00011 , A61B2018/00017 , A61B2018/00029 , A61B2018/00291 , A61B2018/143 , A61B2018/1475 , A61M2025/0085
摘要： A tissue surface treatment apparatus includes a housing having a proximal end, a distal end including a tissue contacting surface, an interior defined by the housing and a handpiece coupled to the housing. The contactinc surface has a plurality of apertures. An energy delivery device including an electrode is positionable in the housing interior. The electrode includes a tissue penetrating distal end in substantial alignment with an aperture. The electrode is configured to be advanced from the housing interior through the aperture and into a target tissue site to define an ablation volume at least partly bounded by a tissue surface. An advancement device is coupled to the energy delivery device and is at least partly positionable within at least one of the housing or the handpiece. The advancement device is configured to advance the electrode from the housing interior into the target tissue site and withdrawal the electrode into the housing interior. A cable is coupled to the housing or the energy delivery device and is configured to be coupled to an energy source.
摘要翻译：组织表面处理设备包括具有近端，远端包括组织接触表面的壳体，由壳体限定的内部和联接到壳体的手持件。触点表面具有多个孔。包括电极的能量输送装置可定位在壳体内部。电极包括与孔基本对准的穿透远端的组织。电极被配置为从壳体内部通过孔推进到目标组织部位以限定至少部分地由组织表面限定的消融体积。进给装置联接到能量输送装置，并且至少部分地可定位在壳体或手持件中的至少一个中。推进装置被配置为将电极从壳体内部推进到目标组织部位并将电极抽出到壳体内部。电缆耦合到壳体或能量输送装置，并且被配置为耦合到能量源。

26. 发明申请

US20050067879A1 Combination panline and utility drilling or bolting unit 有权
标题翻译：组合泛用和公用事业钻孔或螺栓连接单元
公开(公告)号：US20050067879A1
公开(公告)日：2005-03-31
申请号：US10949981
申请日：2004-09-24
申请人： Timothy Burgess , William Kendall , David Morris , Steven Payne
发明人： Timothy Burgess , William Kendall , David Morris , Steven Payne
IPC分类号： E21C27/02 , E21D20/00 , E21D21/00 , E21C37/00
CPC分类号： E21C27/02 , E21D20/003
摘要： A drilling or bolting unit for selective use with either a vehicle or a panline of a face conveyor associated with a longwall miner or mining machine is disclosed. In one embodiment, the unit comprises a base adapted for engaging the panline and a plurality of receivers. Each receiver may be adapted for receiving one of the pair of forks of the vehicle, such that the unit may be used as either a panline drilling or bolting unit or as a utility drilling or bolting unit with the vehicle apart from the panline. Related methods are also described.
摘要翻译：公开了一种用于与长壁采矿机或采矿机相关联的面部输送机的车辆或平面线选择性使用的钻孔或螺栓连接单元。在一个实施例中，该单元包括适于接合平移线和多个接收器的基座。每个接收器可以适于接收车辆的一对叉中的一个，使得该单元可以用作泛线钻孔或螺栓连接单元，或者可以用作车辆远离平移线的公用事业钻井或螺栓单元。还描述了相关方法。

27. 发明申请

US20050035040A1 WATER TREATMENT CARTRIDGE 失效
标题翻译：水处理盒
公开(公告)号：US20050035040A1
公开(公告)日：2005-02-17
申请号：US10638645
申请日：2003-08-12
申请人： Ian Knapp , David Morris
发明人： Ian Knapp , David Morris
IPC分类号： C02F1/00 , C02F1/68 , C02F1/76
CPC分类号： C02F1/688 , C02F1/003 , C02F1/76 , C02F2201/006 , C02F2303/04
摘要： The water treatment cartridge is a cartridge adapted to fit into a conventional water filter housing to release a sanitizing dose of a water-treating chemical, and in particular chlorine dioxide, into a water treatment system or unit process. The cartridge is filled with a water treating media, comprised preferably of a mixture of an inert filler material and a chemical composition that releases chlorine dioxide on contact with water. The concentration of the chlorine dioxide released into the water, as well as the duration of the release, may be varied by the selection of the filler material and amount of the filler material in the water treating media.
摘要翻译：水处理盒是适于装配到常规水过滤器壳体中的筒，以将消毒剂量的水处理化学品，特别是二氧化氯释放到水处理系统或单元过程中。填充有水处理介质，该水处理介质优选地包括惰性填料和与水接触释放二氧化氯的化学组成的混合物。释放到水中的二氧化氯的浓度以及释放的持续时间可以通过填充材料的选择和水处理介质中的填充材料的量来改变。

28. 发明授权

US06664246B2 Pharmaceutical composition 失效
公开(公告)号：US06664246B2
公开(公告)日：2003-12-16
申请号：US09861865
申请日：2001-05-22
申请人： David Morris
发明人： David Morris
IPC分类号： A61K3159
CPC分类号： A61K31/59
摘要： The present invention is concerned with a pharmaceutical composition suitable for the treatment of cancer and in particular with a pharmaceutical composition containing vitamin D or a precursor, analogue or metabolite thereof and the use of these compositions in the treatment of a tumor in a subject.

29. 发明授权

US4538219A Multiwinding inductor and associated apparatus 失效
标题翻译：多绕组电感器及相关设备
公开(公告)号：US4538219A
公开(公告)日：1985-08-27
申请号：US514138
申请日：1983-07-15
申请人： David Morris , Albrecht Schwarz
发明人： David Morris , Albrecht Schwarz
IPC分类号： H02M3/337 , H02M3/335
CPC分类号： H02M3/3378
摘要： A multiwinding inductor is disclosed which inductor is employed in a power control circuit. The power control circuit is of the type having a transformer which has a center tapped primary winding coupled to and associated with a plurality of secondary windings. The primary winding of the transformer is switched by means of switching devices during a power control operation. The inductor has a first winding in the primary which winding has one terminal coupled to the center tap and a second terminal coupled to a generator and a filter arrangement. Another winding of the inductor designated as a free wheeling winding is in series with an auxiliary impedance and has one terminal coupled to the common terminal of the switching devices and a second terminal coupled through a rectifier to the generator. At least two additional windings of the inductor are coupled to suitable rectifier circuits associated with the secondary windings of the transformer. The operation of the inductor causes energy which is stored in the secondary windings to be returned to the generator during circuit operation by means of the free wheeling winding and auxiliary impedance to thereby increase the overall efficiency of the circuit as well as to reduce the magnitude of the filter capacitors employed in such circuits.
摘要翻译：公开了一种多绕组电感器，其在电力控制电路中采用电感器。功率控制电路是具有耦合到多个次级绕组并与多个次级绕组相关联的中心抽头初级绕组的变压器的类型。在功率控制操作期间，通过开关装置来切换变压器的初级绕组。电感器具有初级的第一绕组，该绕组具有耦合到中心抽头的一个端子和耦合到发电机和滤波器装置的第二端子。被称为续流绕组的电感器的另一绕组与辅助阻抗串联，并且具有耦合到开关器件的公共端子的一个端子和通过整流器耦合到发电机的第二端子。电感器的至少两个附加绕组耦合到与变压器的次级绕组相关联的合适的整流器电路。电感器的操作使得存储在次级绕组中的能量在电路操作期间通过续流绕组和辅助阻抗返回到发电机，从而提高了电路的整体效率，并且减小了在这种电路中使用的滤波电容器。

30. 发明授权

US08433087B2 Hearing aid and method of compensation for direct sound in hearing aids 有权
标题翻译：助听器助听器和助听器直接声音补偿方法
公开(公告)号：US08433087B2
公开(公告)日：2013-04-30
申请号：US12185902
申请日：2008-08-05
申请人： Morten Agerbaek Nordahn , David Morris
发明人： Morten Agerbaek Nordahn , David Morris
IPC分类号： H04R25/00
CPC分类号： H04R25/70 , H04R25/356 , H04R25/505 , H04R2225/43 , H04R2460/11 , H04R2460/15
摘要： A hearing aid (200) comprises at least one microphone (210), a signal processing means (220) and an output transducer (230). The signal processing means is adapted to receive an input signal from the microphone. The signal processing means is adapted to apply a hearing aid gain to the input signal to produce an output signal to be output by the output transducer, and the signal processing means further comprises means for adjusting the hearing aid gain up or down until the hearing aid gain differs from the direct transmission gain by more than a predetermined value.
摘要翻译：助听器（200）包括至少一个麦克风（210），信号处理装置（220）和输出换能器（230）。信号处理装置适于从麦克风接收输入信号。所述信号处理装置适用于对所述输入信号施加助听器增益以产生由所述输出换能器输出的输出信号，并且所述信号处理装置还包括用于调节所述助听器增益的装置，直到所述助听器增益不同于直接传输增益超过预定值。

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