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21. 发明授权

US09202271B2 Method for determining a physical property of an object, system, computer readable medium and program element 有权
标题翻译：用于确定对象，系统，计算机可读介质和程序元素的物理属性的方法
公开(公告)号：US09202271B2
公开(公告)日：2015-12-01
申请号：US13642565
申请日：2011-04-18
申请人： Irina Awechter-Stehle , Reinhard Kneser , Juergen Weese
发明人： Irina Awechter-Stehle , Reinhard Kneser , Juergen Weese
IPC分类号： G06K9/00 , G06T7/00 , G06T7/60
CPC分类号： G06T7/0012 , G06T7/62 , G06T2200/04 , G06T2207/30101
摘要： A method and a system for determining a physical property of an object, e.g., a diameter value of an anatomical structure, employs local object context information for determining a local physical property of the object. The context information may be a known or determined cross-sectional shape of the object. In one embodiment, a processor may be configured to provide volumetric image information of the object having a three-dimensional structure; determine the physical property of the object along its three-dimensional structure; determine the object context information of the object; and visualize the object context information and the physical property on a display.
摘要翻译：用于确定对象的物理属性（例如，解剖结构的直径值）的方法和系统使用用于确定对象的本地物理属性的局部对象上下文信息。上下文信息可以是对象的已知或确定的横截面形状。在一个实施例中，处理器可以被配置为提供具有三维结构的对象的体积图像信息; 确定物体沿其三维结构的物理性质; 确定对象的对象上下文信息; 并可视化对象上下文信息和显示器上的物理属性。

22. 发明授权

US08995777B2 Image registration apparatus 有权
标题翻译：图像配准装置
公开(公告)号：US08995777B2
公开(公告)日：2015-03-31
申请号：US13990530
申请日：2011-11-24
申请人： Jochen Peters , Juergen Weese , Helko Lehmann
发明人： Jochen Peters , Juergen Weese , Helko Lehmann
IPC分类号： G06K9/62 , G06T7/00
CPC分类号： G06T7/0046 , G06T7/344 , G06T7/75 , G06T2207/10072 , G06T2207/20016 , G06T2207/30048
摘要： The invention relates to an image registration apparatus for registering a first image and a second image with respect to each other. A model, which has a fixed topology, is adapted to the first image for generating a first adapted model and to the second image for generating a second adapted model, and corresponding image elements (40, 48, 49; 50, 58, 9) are determined in the first image and in the second image based on spatial positions of first image elements in the first image with respect to the first adapted model and spatial positions of second image elements in the second image with respect to the second adapted model. Since the model has a fixed topology, corresponding image elements can relatively reliably be found based on the adapted models, even if the first and second images show objects having complex properties like a heart, thereby improving the registration quality.
摘要翻译：本发明涉及一种用于相对于彼此登记第一图像和第二图像的图像配准装置。具有固定拓扑的模型适于产生第一适应模型的第一图像和用于产生第二适应模型的第二图像，以及对应的图像元素（40,48,49; 50,58,9）基于第一图像中的第一图像元素相对于第一适应模型的空间位置和第二图像中的第二图像元素相对于第二适应模型的空间位置，在第一图像和第二图像中确定。由于该模型具有固定的拓扑结构，所以即使第一和第二图像显示具有如心脏等复杂属性的对象，因此可以相对可靠地找到相应的图像元素，从而提高注册质量。

23. 发明申请

US20130230225A1 IDENTIFYING INDIVIDUAL SUB-REGIONS OF THE CARDIOVASCULAR SYSTEM FOR CALCIUM SCORING 有权
标题翻译：识别用于钙分析的心脏血管系统的个体分区
公开(公告)号：US20130230225A1
公开(公告)日：2013-09-05
申请号：US13884617
申请日：2011-11-09
申请人： Irina Waechter-Stehle , Reinhard Kneser , Juergen Weese
发明人： Irina Waechter-Stehle , Reinhard Kneser , Juergen Weese
IPC分类号： G06T7/00
CPC分类号： G06T7/0014 , A61B6/032 , A61B6/463 , A61B6/466 , A61B6/503 , A61B6/504 , A61B6/5217 , G06K2209/05 , G06T7/0012 , G06T7/11 , G06T7/136 , G06T2207/10081 , G06T2207/30048 , G06T2207/30101
摘要： A method includes identifying a plurality of different anatomical sub-regions of the cardiovascular system of a subject in image data of the subject based on a subject specific cardiovascular anatomical model, wherein the plurality of different regions corresponds to regions where calcifications occur, searching for and identifying calcifications in the sub-regions based on voxel grey value intensity values of the image data, and generating a signal indicative of one or more regions of voxels of the image data respectively corresponding to sub-regions including identified calcifications. A computing system (118) includes a processor that automatically determines a plurality of different groups of voxels of image data of a subject, wherein each group of voxels corresponds to a different sub-region of the cardiovascular system of the subject and each group of voxels corresponds to a region that includes a calcification identified in the image data.
摘要翻译：一种方法包括基于主题特异性心血管解剖模型来识别对象的图像数据中的受试者的心血管系统的多个不同解剖子区域，其中所述多个不同区域对应于发生钙化的区域，搜索和基于图像数据的体素灰度值强度值来识别子区域中的钙化，以及生成指示分别对应于包括识别的钙化的子区域的图像数据的一个或多个体素的区域的信号。计算系统（118）包括处理器，其自动确定对象的图像数据的多个不同体素组，其中每组体素对应于受试者的心血管系统的不同子区域和每组体素对应于包括在图像数据中标识的钙化的区域。

24. 发明申请

US20090216111A1 PROCESSING OF IMAGES OF INTERVENTIONAL INSTRUMENTS WITH MARKERS 有权
标题翻译：传统仪器与标记的图像处理
公开(公告)号：US20090216111A1
公开(公告)日：2009-08-27
申请号：US11573292
申请日：2005-07-21
申请人： Juergen Weese , Sabine Mollus , Raoul Florent , Lucile Nosjean , Pierre Lelong , Peter Maria Johannes Rongen
发明人： Juergen Weese , Sabine Mollus , Raoul Florent , Lucile Nosjean , Pierre Lelong , Peter Maria Johannes Rongen
IPC分类号： A61B6/12 , A61B19/00
CPC分类号： A61B34/20 , A61B90/39 , A61B90/90 , A61B2034/2065 , A61B2090/392
摘要： The invention relates to a method and an image processing system (20) for the evaluation of projection images (25) generated by an X-ray imaging system (10), wherein the images (25) may show different instruments (51, 52) of a given set of interventional instruments like catheters or guide wires. The instruments are equipped with markers such that their configuration is characteristic of the corresponding instrument (51, 52). Preferably three markers are arranged on a straight line, the ratio of the distances between them being characteristic for the corresponding instrument. The image processing system (20) may then identify the instruments (51, 52) present in a given projection (25) and provide functionalities for a user that correspond to said instruments. Moreover, the system may be used to locate an instrument (51, 52) of interest in a projection image (25) if the marker configuration of that instrument (51, 52) is known a priori.
摘要翻译：本发明涉及一种用于评估由X射线成像系统（10）产生的投影图像（25）的方法和图像处理系统（20），其中图像（25）可以显示不同的仪器（51,52）一套给定的介入仪器，如导管或导丝。仪器配备有标记，使得它们的配置是相应仪器（51,52）的特征。优选地，三个标记布置在直线上，它们之间的距离比对于相应的仪器是特征的。然后，图像处理系统（20）可以识别存在于给定投影（25）中的仪器（51,52），并为与用户对应的所述仪器提供功能。此外，如果先前已知该仪器（51,52）的标记结构，则该系统可用于在投影图像（25）中定位感兴趣的仪器（51,52）。

25. 发明申请

US20090030657A1 SURFACE TESSELATION OF SHAPE MODELS 审中-公开
标题翻译：形状模型的表面压力
公开(公告)号：US20090030657A1
公开(公告)日：2009-01-29
申请号：US12097141
申请日：2006-12-15
申请人： Jens Von Berg , Frans Andreas Gerritsen , Juergen Weese , Cristian Lorenz , Jochen Peters , Olivier Ecabert
发明人： Jens Von Berg , Frans Andreas Gerritsen , Juergen Weese , Cristian Lorenz , Jochen Peters , Olivier Ecabert
IPC分类号： G06F17/50
CPC分类号： G06T17/20 , G06T17/10 , G06T17/205
摘要： The invention relates to a method (100) of and to a system (200) for determining a template mesh of a shape model on the basis of a plurality of instances of the shape model. The method of determining the template mesh of the shape model comprises an obtaining step (110) for obtaining the plurality of instances of the template mesh, a computing step (120) for computing a plurality of results on the basis of the plurality of instances of the shape model, a deciding step (130) for deriving a decision on the basis of the plurality of results, and a decimating step (140) for decimating the template mesh of the shape model on the basis of the decision, thereby determining the template mesh of the shape model. Thus, the template mesh of the shape model determined by the method of the invention better describes objects of interest at all locations.
摘要翻译：本发明涉及一种用于基于形状模型的多个实例来确定形状模型的模板网格的系统（200）的方法（100）。确定形状模型的模板网格的方法包括获取步骤（110），用于获得模板网格的多个实例;计算步骤（120），用于基于多个实例的多个实例来计算多个结果形状模型，用于基于多个结果导出判定的判定步骤（130），以及基于判定来抽取形状模型的模板网格的抽取步骤（140），从而确定模板形状模型的网格。因此，通过本发明的方法确定的形状模型的模板网格更好地描述了所有位置处的感兴趣对象。

26. 发明申请

US20080246770A1 Method of Generating a 2-D Image of a 3-D Object 审中-公开
标题翻译：生成3-D物体的二维图像的方法
公开(公告)号：US20080246770A1
公开(公告)日：2008-10-09
申请号：US12064671
申请日：2006-08-23
申请人： Gundolf Kiefer , Juergen Weese
发明人： Gundolf Kiefer , Juergen Weese
IPC分类号： G06T11/20
CPC分类号： G06T15/50
摘要： There is described a method for generating a 2-D image of a 3-D object represented by a volume data set comprising a multiplicity of data points each having an opacity value. A plurality of notional rays are cast through the 3-D object and for each ray, a ray path is divided into a plurality of base sampling intervals defined by data points on the path. If it is determined that a difference in opacity values across a base sampling interval can become greater than a pre-determined value, successively smaller sampling regions are generated within the base sampling interval until it is determined that a difference in opacity values across each generated smaller sampling interval in the base interval is less than the pre-determined threshold. Values indicative of an interaction between the ray and the 3-D object in the sampling intervals along the path are accumulated using a direct volume rendering procedure to determine a pixel value in the 2-D image.
摘要翻译：描述了一种用于产生由包括多个数据点的体数据集合表示的3-D对象的二维图像的方法，每个数据点具有不透明度值。通过3-D物体投射多个意向射线，并且对于每个射线，射线路径被划分为由路径上的数据点定义的多个基本采样间隔。如果确定跨基准采样间隔的不透明度值的差异可能变得大于预定值，则在基本采样间隔内产生相继较小的采样区域，直到确定每个产生的不透明度值的差异较小基准间隔中的采样间隔小于预定阈值。使用直接体积绘制程序累积沿着路径的采样间隔中指示射线与3-D物体之间的相互作用的值，以确定2-D图像中的像素值。

27. 发明授权

US09393079B2 Processing of images of interventional instruments with markers 有权
标题翻译：用标记处理介入仪器的图像
公开(公告)号：US09393079B2
公开(公告)日：2016-07-19
申请号：US11573292
申请日：2005-07-21
申请人： Juergen Weese , Sabine Mollus , Raoul Florent , Lucile Nosjean , Pierre Lelong , Peter Maria Johannes Rongen
发明人： Juergen Weese , Sabine Mollus , Raoul Florent , Lucile Nosjean , Pierre Lelong , Peter Maria Johannes Rongen
IPC分类号： A61B5/05 , A61B19/00
CPC分类号： A61B34/20 , A61B90/39 , A61B90/90 , A61B2034/2065 , A61B2090/392
摘要： A method and an image processing system for the evaluation of projection images generated by an X-ray imaging system, wherein the images may show different instruments of a given set of interventional instruments like catheters or guide wires. The instruments are equipped with markers such that their configuration is characteristic of the corresponding instrument. Preferably three markers are arranged on a straight line, the ratio of the distances between them being characteristic for the corresponding instrument. The image processing system may then identify the instruments present in a given projection and provide functionalities for a user that correspond to said instruments. Moreover, the system may be used to locate an instrument of interest in a projection image if the marker configuration of that instrument is known a priori.
摘要翻译：一种用于评估由X射线成像系统产生的投影图像的方法和图像处理系统，其中所述图像可以显示给定的一组介入装置如导管或导丝的不同仪器。这些仪器配有标记，使得它们的配置是相应仪器的特征。优选地，三个标记布置在直线上，它们之间的距离比对于相应的仪器是特征的。然后，图像处理系统可以识别给定投影中存在的工具，并为与用户对应的功能提供功能。此外，如果该仪器的标记配置是先验已知的，则该系统可用于在投影图像中定位感兴趣的仪器。

28. 发明授权

US09256951B2 System for rapid and accurate quantitative assessment of traumatic brain injury 有权
标题翻译：快速准确地定量评估创伤性脑损伤的系统
公开(公告)号：US09256951B2
公开(公告)日：2016-02-09
申请号：US13514713
申请日：2010-11-17
申请人： Lyubomir Georgiev Zagorchev , Elizabeth Anne Morre , Matthew A. Garlinghouse , Robert M. Roth , Thomas W. McAllister , Dieter Geller , Jochen Peters , Juergen Weese , Yuechen Qian
发明人： Lyubomir Georgiev Zagorchev , Elizabeth Anne Morre , Matthew A. Garlinghouse , Robert M. Roth , Thomas W. McAllister , Reinhard Kneser , Dieter Geller , Jochen Peters , Juergen Weese , Yuechen Qian
IPC分类号： G06T7/00 , G06T17/30 , G06T19/20
CPC分类号： G06T7/0089 , G06T7/0012 , G06T7/149 , G06T2200/24 , G06T2207/10081 , G06T2207/30016
摘要： A system and method for automatic segmentation, performed by selecting a deformable model of an anatomical structure of interest imaged in a volumetric image, the deformable model formed of a plurality of polygons including vertices and edges, displaying the deformable model on a display, detecting a feature point of the anatomical structure of interest corresponding to each of the plurality of polygons and adapting the deformable model by moving each of the vertices toward the corresponding feature points until the deformable model morphs to a boundary of the anatomical structure of interest, forming a segmentation of the anatomical structure of interest.
摘要翻译：一种用于自动分割的系统和方法，通过选择在体积图像中成像的感兴趣的解剖结构的可变形模型来执行，所述可变形模型由包括顶点和边缘的多个多边形形成，在显示器上显示可变形模型，感兴趣的解剖结构的特征点对应于多个多边形中的每一个，并且通过将每个顶点朝向对应的特征点移动来适配可变形模型，直到可变形模型变形为感兴趣的解剖结构的边界，形成分割的感兴趣的解剖结构。

29. 发明授权

US08260586B2 Method of and a system for adapting a geometric model using multiple partial transformations 有权
标题翻译：使用多个部分变换来适应几何模型的方法和系统
公开(公告)号：US08260586B2
公开(公告)日：2012-09-04
申请号：US12067841
申请日：2006-09-20
申请人： Olivier Ecabert , Jochen Peters , Juergen Weese
发明人： Olivier Ecabert , Jochen Peters , Juergen Weese
IPC分类号： G06F7/60 , G06F17/10
CPC分类号： G06T7/149 , G06T7/12 , G06T2207/10072 , G06T2207/30048
摘要： The invention relates to a method (100) of adapting a geometric model to an image data comprising determining a first partial transformation for mapping a first part of the geometric model into the image data and a second partial transformation for mapping a second part of the geometric model into the image data. By determining the first partial transformation of the first part of the geometric model and the second partial transformation of the second part of the geometric model, the geometric model can assume more shapes and therefore can be more accurately adapted to an object comprised in the image data.
摘要翻译：本发明涉及一种将几何模型适应于图像数据的方法（100），包括确定用于将几何模型的第一部分映射到图像数据中的第一部分变换，以及用于映射几何的第二部分的第二部分变换模型进入图像数据。通过确定几何模型的第一部分的第一部分变换和几何模型的第二部分的第二部分变换，几何模型可以呈现更多的形状，因此可以更准确地适应包含在图像数据中的对象。

30. 发明申请

US20100293505A1 ANATOMY-RELATED IMAGE-CONTEXT-DEPENDENT APPLICATIONS FOR EFFICIENT DIAGNOSIS 审中-公开
标题翻译：与解剖学相关的图像依赖性应用程序进行有效的诊断
公开(公告)号：US20100293505A1
公开(公告)日：2010-11-18
申请号：US12376999
申请日：2007-08-07
申请人： Gundolf Kiefer , Helko Lehmann , Dieter Geller , Hauke Schramm , Jochen Peters , Olivier Ecabert , Juergen Weese
发明人： Gundolf Kiefer , Helko Lehmann , Dieter Geller , Hauke Schramm , Jochen Peters , Olivier Ecabert , Juergen Weese
IPC分类号： G06F3/048
CPC分类号： G16H40/63
摘要： The invention relates to a system (100) for obtaining information relating to segmented volumetric medical image data, the system comprising: a display unit (110) for displaying a view of the segmented volumetric medical image data on a display; an indication unit (115) for indicating a location on the displayed view; a trigger unit (120) for triggering an event; an identification unit (125) for identifying a segmented anatomical structure comprised in the segmented volumetric medical image data based on the indicated location on the displayed view in response to the triggered event; and an execution unit (130) for executing an action associated with the identified segmented anatomical structure, thereby obtaining information relating to the segmented volumetric medical image data. The action executed by the execution unit (130) may be displaying a name of the segmented anatomical structure, a short description of the segmented anatomical structure, or a hint on a potential malformation or malfunction of the segmented anatomical structure. Thus, the system (100) allows obtaining valuable information relating to the volumetric medical image data viewed by a physician on the display, thereby assisting the physician in medical diagnosing.
摘要翻译：本发明涉及一种用于获取与分段体积医学图像数据相关的信息的系统（100），该系统包括：显示单元（110），用于在显示器上显示分割的体积医学图像数据的视图; 指示单元（115），用于指示所显示的视图上的位置; 触发单元（120），用于触发事件; 识别单元（125），用于响应于触发的事件，基于所显示的视图上的指示位置来识别包含在所述分段体积医学图像数据中的分段解剖结构; 以及执行单元（130），用于执行与所识别的分段解剖结构相关联的动作，从而获得与分割的体积医学图像数据相关的信息。由执行单元（130）执行的动作可以显示分割的解剖结构的名称，分割的解剖结构的简短描述，或对分割的解剖结构的潜在畸形或故障的提示。因此，系统（100）允许获得与医生在显示器上观看的体积医学图像数据相关的有价值的信息，从而辅助医师进行医学诊断。

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