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21. 发明授权

US08700958B2 Multi-variate network survivability analysis 有权
标题翻译：多变量网络生存性分析
公开(公告)号：US08700958B2
公开(公告)日：2014-04-15
申请号：US13412623
申请日：2012-03-06
申请人： Vanko Vankov , Vinod Jeyachandran , Pradeep K. Singh , Alain J. Cohen , Shobana Narayanaswamy
发明人： Vanko Vankov , Vinod Jeyachandran , Pradeep K. Singh , Alain J. Cohen , Shobana Narayanaswamy
IPC分类号： G06F11/00
CPC分类号： H04L41/0681 , H04L41/5009 , H04L43/0876 , H04L43/16
摘要： Network survivability is quantified in such a way that failure cases can be compared and ranked against each other in terms of the severity of their impact on the various performance measures associated with the network. The degradation in network performance caused by each failure is quantified based on user-defined sets of thresholds of degradation severity for each performance measure. Each failure is simulated using a model of the network, and a degradation vector is determined for each simulated failure. A comparison function is defined to map the degradation vectors into an ordered set, and this ordered set is used to create an ordered list of network failures, in order of the network degradation caused by each failure.
摘要翻译：网络生存能力被量化，使得故障案例可以根据其对与网络相关联的各种性能测量的影响的严重性彼此进行比较和排名。基于用户定义的每个性能测量的劣化严重性阈值集，量化每个故障导致的网络性能的下降。使用网络模型模拟每个故障，并为每个模拟故障确定劣化矢量。定义比较函数将劣化向量映射到有序集合中，并且该有序集合用于按照由每个故障引起的网络劣化的顺序来创建网络故障的有序列表。

22. 发明授权

US08699493B2 Routing validation 有权
标题翻译：路由验证
公开(公告)号：US08699493B2
公开(公告)日：2014-04-15
申请号：US13412604
申请日：2012-03-05
申请人： Alain J. Cohen , Pradeep K. Singh , Vinod Jeyachandran , Nitin Gupta
发明人： Alain J. Cohen , Pradeep K. Singh , Vinod Jeyachandran , Nitin Gupta
IPC分类号： H04L12/28
CPC分类号： H04L45/28 , H04L41/0631 , H04L41/08 , H04L41/0866 , H04L41/14 , H04L41/145 , H04L45/02 , H04L45/124
摘要： A simulator simulates routing system protocols to build routing tables corresponding to a modeled network, and a comparator compares the routing tables in the actual network to these simulator-created routing tables. Because the modeled system represents a fault-free version of the actual system, and assuming that the modeled routing system protocols are representative of the algorithms used in the actual routers, these simulator-produced routing tables can represent steady-state routing tables that should be present in the routers of the actual network at steady state. By querying each router in the actual network for its routing table and comparing each routing table to the corresponding simulator-produced routing table, any differences from the steady state can be identified.
摘要翻译：模拟器模拟路由系统协议以构建与建模网络相对应的路由表，并且比较器将实际网络中的路由表与这些模拟器创建的路由表进行比较。因为建模的系统代表了实际系统的无故障版本，并且假设建模的路由系统协议代表了实际路由器中使用的算法，这些模拟器生成的路由表可以表示应该是稳态路由表存在于稳定状态下实际网络的路由器。通过查询实际网络中的每个路由器的路由表，并将每个路由表与相应的模拟器生成的路由表进行比较，可以识别与稳态的任何差异。

23. 发明申请

US20090052333A1 TRAFFIC INDEPENDENT SURVIVABILITY ANALYSIS 有权
标题翻译：交通费独立生存率分析
公开(公告)号：US20090052333A1
公开(公告)日：2009-02-26
申请号：US12195393
申请日：2008-08-20
申请人： Vanko Vankov , Arun Pasupathy , Vinod Jeyachandran , Pradeep K. Singh , Alain J. Cohen , Yonghuan Cao
发明人： Vanko Vankov , Arun Pasupathy , Vinod Jeyachandran , Pradeep K. Singh , Alain J. Cohen , Yonghuan Cao
IPC分类号： G06F11/30
CPC分类号： H04L43/50
摘要： First-order effects of hypothesized fault conditions are determined by propagating discrete test packets between select nodes and noting the change of path, if any, taken by the test packet under each condition relative to the fault-free path. Tools are provided to create classes of node pairs of interest, and test packets are created only for select classes. The network is analyzed to identify fault conditions that are likely to impact system performance, and only these fault conditions are simulated. By providing a methodology for selecting classes of node pairs to test, and prioritizing the faults to simulate, a first-order survivability analysis of large networks can be performed efficiently and effectively. The efficiency of this technique is also enhanced by providing test packets that are representative of a wide range of possible source-destination combinations, and by evaluating only the source-destination combinations that may be directly affected by each fault condition.
摘要翻译：通过在选择节点之间传播离散的测试包，并注意到每个条件下相对于无故障路径，由测试包采取的路径（如果有的话）的变化来确定假设故障条件的一阶影响。提供工具来创建感兴趣的节点对类，并且只为选择类创建测试包。分析网络以识别可能影响系统性能的故障状况，并且仅模拟这些故障条件。通过提供一种选择要测试的节点对的类别并对故障进行优先级模拟的方法，可以有效和高效地执行大型网络的一阶生存性分析。通过提供表示广泛范围的可能的源 - 目的地组合的测试分组以及通过仅评估可能由每个故障状况直接影响的源 - 目的地组合来增强该技术的效率。

24. 发明授权

US07446089B2 Methods of inhibiting and treating bacterial biofilms by metal chelators 失效
标题翻译：金属螯合剂抑制和治疗细菌生物膜的方法
公开(公告)号：US07446089B2
公开(公告)日：2008-11-04
申请号：US10958923
申请日：2004-10-04
申请人： Pradeep K. Singh , Michael J. Welsh , Everett P. Greenberg
发明人： Pradeep K. Singh , Michael J. Welsh , Everett P. Greenberg
IPC分类号： A61K38/00 , A61K39/40
CPC分类号： A61K38/40 , A01N61/00 , A01N63/02 , A23B4/20 , A23B4/22 , A23L3/34635 , A23L3/3526 , A23L3/3571 , A61L2/0082 , A61L2/16 , A61L2/186 , A61L2202/24
摘要： The invention presented herein provides methods and compositions for the prevention and treatment of bacterial infections. The methods are based on the discovery that depletion of bioavailable iron stimulates surface motility in bacteria thus inhibiting the ability of a bacterial population to develop into a biofilm.
摘要翻译：本发明提供了用于预防和治疗细菌感染的方法和组合物。这些方法是基于发现生物可利用的铁的消耗刺激细菌中的表面运动，从而抑制细菌群体发展成生物膜的能力。

25. 发明授权

US09539367B2 Gallium inhibits biofilm formation 有权
标题翻译：镓抑制生物膜形成
公开(公告)号：US09539367B2
公开(公告)日：2017-01-10
申请号：US11004049
申请日：2004-12-03
申请人： Bradley E. Britigan , Pradeep K. Singh
发明人： Bradley E. Britigan , Pradeep K. Singh
IPC分类号： A61L27/54 , A61K31/28 , A61K33/24 , A01N59/16 , A61L27/30 , A61L29/10 , A61L29/16
CPC分类号： A61L27/54 , A01N59/16 , A61K31/28 , A61K33/24 , A61L27/306 , A61L29/106 , A61L29/16 , A61L2300/102 , A61L2300/404
摘要： The present invention provides a gallium-containing composition for coating/impregnating a device or device surface to prevent biofilm growth formation. The present invention also provides a method of preventing or inhibiting biofilm growth formation. The present invention also provides methods for killing established biofilms.
摘要翻译：本发明提供了一种用于涂覆/浸渍装置或装置表面以防止生物膜生长形成的含镓组合物。本发明还提供了预防或抑制生物膜生长形成的方法。本发明还提供了杀死已建立的生物膜的方法。

26. 发明申请

US20090279496A1 DEDICATED AND PRIORITY BASED ALLOCATION IN MULTI-HOP WIRELESS SYSTEMS 审中-公开
标题翻译：多重无线系统中基于优先级和优先级的分配
公开(公告)号：US20090279496A1
公开(公告)日：2009-11-12
申请号：US12435932
申请日：2009-05-05
申请人： Majid Raissi-Dehkordi , Karthikeyan Chandrashekar , Paul M. Janes , Ibrahim Utku Moral , Pradeep K. Singh
发明人： Majid Raissi-Dehkordi , Karthikeyan Chandrashekar , Paul M. Janes , Ibrahim Utku Moral , Pradeep K. Singh
IPC分类号： H04W72/04
CPC分类号： H04W16/04 , H04W72/048 , H04W72/082 , H04W84/18
摘要： A transmission channel allocation scheme for a multi-hop wireless network takes into account the priority of users, particular application requirements, applicable contractual requirements, and other factors. The channel allocation scheme determines which nodes can share a common channel for transmission without interference, and distinguishes between resources that must be dedicated to each node based on the requirements associated with each node, and the resources that are dynamically provided to each node, based on the current traffic demand. Additionally, resources that are not required to satisfy explicit requests are allocated among the nodes, thereby allowing nodes to sometimes avoid the delays associated with the access request process.
摘要翻译：多跳无线网络的传输信道分配方案考虑到用户的优先级，特定应用要求，适用的合同要求等因素。信道分配方案确定哪些节点可以共享公共信道以进行无干扰的传输，并且基于与每个节点相关联的需求以及动态地提供给每个节点的资源来区分必须专用于每个节点的资源，基于目前的交通需求。此外，在节点之间分配不需要满足显式请求的资源，从而允许节点有时避免与访问请求过程相关联的延迟。

27. 发明授权

US08343911B2 Methods of inhibiting and treating bacterial biofilms by metal chelators 有权
标题翻译：金属螯合剂抑制和治疗细菌生物膜的方法
公开(公告)号：US08343911B2
公开(公告)日：2013-01-01
申请号：US12288449
申请日：2008-10-20
申请人： Pradeep K. Singh , Michael J. Welsh , E. Peter Greenberg
发明人： Pradeep K. Singh , Michael J. Welsh , E. Peter Greenberg
IPC分类号： A61K38/00 , A61K38/40
CPC分类号： A61K38/40 , A01N61/00 , A01N63/02 , A23B4/20 , A23B4/22 , A23L3/34635 , A23L3/3526 , A23L3/3571 , A61L2/0082 , A61L2/16 , A61L2/186 , A61L2202/24
摘要： The invention presented herein provides methods and compositions for the prevention and treatment of bacterial infections. The methods are based on the discovery that depletion of bioavailable iron stimulates surface motility in bacteria thus inhibiting the ability of a bacterial population to develop into a biofilm.
摘要翻译：本发明提供了用于预防和治疗细菌感染的方法和组合物。这些方法是基于发现生物可利用的铁的消耗刺激细菌中的表面运动，从而抑制细菌群体发展成生物膜的能力。

28. 发明申请

US20120142583A1 Methods of inhibiting and treating bacterial biofilms by metal chelators 有权
标题翻译：金属螯合剂抑制和治疗细菌生物膜的方法
公开(公告)号：US20120142583A1
公开(公告)日：2012-06-07
申请号：US12288449
申请日：2008-10-20
申请人： Pradeep K. Singh , Michael J. Welsh , Everett P. Greenberg
发明人： Pradeep K. Singh , Michael J. Welsh , Everett P. Greenberg
IPC分类号： A61K38/40 , A61P31/04 , A61K38/38
CPC分类号： A61K38/40 , A01N61/00 , A01N63/02 , A23B4/20 , A23B4/22 , A23L3/34635 , A23L3/3526 , A23L3/3571 , A61L2/0082 , A61L2/16 , A61L2/186 , A61L2202/24
摘要： The invention presented herein provides methods and compositions for the prevention and treatment of bacterial infections. The methods are based on the discovery that depletion of bioavailable iron stimulates surface motility in bacteria thus inhibiting the ability of a bacterial population to develop into a biofilm.
摘要翻译：本发明提供了用于预防和治疗细菌感染的方法和组合物。这些方法是基于发现生物可利用的铁的消耗刺激细菌中的表面运动，从而抑制细菌群体发展成生物膜的能力。

29. 发明授权

US07219047B2 Simulation with convergence-detection skip-ahead 有权
标题翻译：模拟与收敛检测跳过
公开(公告)号：US07219047B2
公开(公告)日：2007-05-15
申请号：US10112179
申请日：2002-03-28
申请人： Alain Cohen , Pradeep K. Singh , Arun Pasupathy , Stefan Znam
发明人： Alain Cohen , Pradeep K. Singh , Arun Pasupathy , Stefan Znam
IPC分类号： G06F17/50
CPC分类号： G06F17/5009 , H04L67/38
摘要： A sub-system is provided to a discrete event simulator (DES) to expedite simulation execution by first detecting a non-quiescent steady-state condition in the simulated system, and when the steady-state condition is detected, the simulator determines a state, and subsequently simulates the system at a skip-ahead time using this determined state, or a predicted state based on the determined state. Convergence analysis is used to determine whether the system is at, or approaching, a steady-state condition. This convergence skip-ahead process achieves faster analysis by avoiding the computation that would conventionally be required to simulate the system behavior during the time interval that is skipped.
摘要翻译：将子系统提供给离散事件模拟器（DES），以通过首先检测模拟系统中的非静态稳态条件来加速模拟执行，并且当检测到稳态条件时，模拟器确定状态，并且随后使用该确定的状态或基于所确定的状态的预测状态在跳过预测时间模拟系统。收敛分析用于确定系统是处于或接近稳态条件。这种汇聚跳过进程通过避免在跳过的时间间隔期间模拟系统行为通常需要的计算来实现更快的分析。

30. 发明授权

US07139692B2 Flow propagation analysis using iterative signaling 有权
标题翻译：使用迭代信令的流传播分析
公开(公告)号：US07139692B2
公开(公告)日：2006-11-21
申请号：US10325148
申请日：2002-12-20
申请人： Alain Cohen , Pradeep K. Singh , Arun Pasupathy , Stefan Znam , Marius Popa
发明人： Alain Cohen , Pradeep K. Singh , Arun Pasupathy , Stefan Znam , Marius Popa
IPC分类号： G06F9/44
CPC分类号： H04L41/145
摘要： A method and system for flow propagation analysis uses ‘tracers’ that are iteratively propagated through a simulated network between source and destination elements. These tracers are structured to contain traffic flow information from source to destination, and to reflect changes as the flow is affected by each element along the path from source to destination. The resultant flow information at the destination corresponds to the effective throughput from the source to the destination, and the flow information at the output of each intermediate element in the network corresponds to the potentially achievable throughput through that element for the given source-to-destination flow.
摘要翻译：用于流传播分析的方法和系统使用通过源和目标元素之间的模拟网络迭代地传播的“示踪物”。这些跟踪器被构造成包含从源到目的地的流量信息，并且当流被源从源到目的地的路径的每个元素影响时反映改变。目的地的结果流信息对应于从源到目的地的有效吞吐量，并且网络中的每个中间元素的输出处的流信息对应于通过该元素对于给定源到目的地的潜在可实现的吞吐量流。

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