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    • 22. 发明授权
    • Method and device for assessing perfusion failure in a patient
    • 评估患者灌注失败的方法和装置
    • US06216024B1
    • 2001-04-10
    • US09160224
    • 1998-09-24
    • Max Harry WeilWanchun TangJose Bisera
    • Max Harry WeilWanchun TangJose Bisera
    • A61B500
    • A61B5/0261A61B5/14542A61B5/1473A61B5/412A61B5/42A61B5/682
    • Methods and devices are provided for assessing impairment of blood circulation in a patient, such as that in perfusion failure, by measurement of pCO2 (partial pressure of carbon dioxide) in the upper digestive and/or respiratory tract of the patient. The method comprises introducing a carbon dioxide sensor into the upper digestive and/or respiratory tract of a patient, without passing the sensor down through or beyond the patient's epiglottis. Specifically, a carbon dioxide sensor is placed adjacent a mucosal surface within the upper digestive and/or respiratory tract, preferably within the patient's mouth or inside the patient's nose. By avoiding passage through the mouth into the throat and esophagus, discomfort is substantially avoided and the potential for injury minimized. Previously, the belief in the art was that increased partial pressure of carbon dioxide was a localized phenomenon during perfusion failure; however, applicants have now discovered that increases in tissue CO2 occur throughout the body during perfusion failure, and the method and device of the invention are premised on this discovery.
    • 提供了通过测量患者上消化道和/或呼吸道中pCO2(二氧化碳分压)来评估患者血液循环障碍(如灌注失败)的方法和装置。 该方法包括将二氧化碳传感器引入患者的上消化道和/或呼吸道中,而不会使传感器向下穿过或超过患者的会厌。 具体来说,将二氧化碳传感器放置在上消化道和/或呼吸道内的粘膜表面附近,优选在病人口内或患者鼻内。 通过避免通过口腔进入喉咙和食道,基本上避免了不适,并减少了伤害的可能性。 以前,对艺术的信念是,二氧化碳的分压增加是灌注失败期间的局部现象; 然而,申请人现在已经发现,在灌注失败期间,整个身体中发生组织CO 2的增加,并且本发明的方法和装置以该发现为前提。