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    • 22. 发明申请
    • Blood coagulation promoter and blood collection tube
    • 血液凝固促进剂和采血管
    • US20060171915A1
    • 2006-08-03
    • US10548541
    • 2004-04-21
    • Ryusuke OkamotoKatsuya TogawaHironobu Isogawa
    • Ryusuke OkamotoKatsuya TogawaHironobu Isogawa
    • A61K38/48A61K31/765A61K31/785
    • C08L71/02A61B5/15003A61B5/150755A61B5/154B01L3/5082C08L2666/04
    • The present invention provides a blood coagulation promoter capable of exerting both excellent blood coagulation promoting ability and excellent blood clot detaching ability; and a blood collection tube accommodating the blood coagulation promoter. The present invention provides a blood coagulation promoter which includes a hardly water soluble polyoxyalkylene derivative; a partially saponificated polyvinyl alcohol; at least one substance selected from the group consisting of adsorptive inorganic substances and hydrolases capable of hydrolyzing a bond between Arg and an arbitrary amino acid reside and/or a bond between Lys and an arbitrary amino acid residue in a peptide chain; a polyvinylpyrrolidone; and preferably a water-soluble silicone oil, and a blood collection tube in which the blood coagulation promoter is accommodated in a tubular vessel having a bottom.
    • 本发明提供能够发挥优异的凝血促进能力和优异的血块分离能力的凝血促进剂; 以及容纳血液凝固促进剂的采血管。 本发明提供一种凝血促进剂,其包含难溶于水的聚氧化烯衍生物; 部分皂化聚乙烯醇; 选自吸附性无机物质和能够水解Arg和任意氨基酸之间的键的水解物中的至少一种物质存在于肽链中Lys和任意氨基酸残基之间的和/或之间的键; 聚乙烯吡咯烷酮 优选水溶性硅油,以及血液收集管,其中所述血液凝固促进剂容纳在具有底部的管状容器中。