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21. 发明申请

US20120230956A1 BIFIDOBACTERIUM LONGUM AND FUNCTIONAL GI DISORDERS 审中-公开
标题翻译：双歧杆菌和功能性胃肠疾病
公开(公告)号：US20120230956A1
公开(公告)日：2012-09-13
申请号：US13391343
申请日：2010-08-24
申请人： Peter McLean , Gabriela Bergonzelli de Gonda , Stephen Michael Collins , Premysl Bercik , Elena Verdu de Bercik
发明人： Peter McLean , Gabriela Bergonzelli de Gonda , Stephen Michael Collins , Premysl Bercik , Elena Verdu de Bercik
IPC分类号： A61K35/74 , A61P1/12 , A61P25/00 , A61P1/00
CPC分类号： A61K35/74 , A23K10/18 , A23K20/163 , A23L33/135 , A23L33/21 , A23V2002/00 , A23Y2300/55 , A61K35/745 , C12N1/20 , A23V2200/32 , A23V2200/3204
摘要： The present invention generally relates to the field of probiotic bacteria. In particular it relates to Bifidobacterium longum, such as Bifidobacterium longum ATCC BAA-999, and its use in ingestible compositions. The composition described in the present invention may be used to treat or prevent functional GI disorders.
摘要翻译：本发明一般涉及益生菌的领域。特别地涉及长双歧杆菌，例如长双歧杆菌ATCC BAA-999，以及其在可摄取组合物中的用途。本发明中描述的组合物可用于治疗或预防功能性GI障碍。

22. 发明授权

US08128984B2 Implantable material and a method for the preparation thereof 有权
标题翻译：可植入材料及其制备方法
公开(公告)号：US08128984B2
公开(公告)日：2012-03-06
申请号：US12990399
申请日：2009-04-30
申请人： David Philip Knight , Nicholas James Vavasour Skaer , Andrew Michael Collins , Tom Louis Dirk Gheysens , Christopher Holland
发明人： David Philip Knight , Nicholas James Vavasour Skaer , Andrew Michael Collins , Tom Louis Dirk Gheysens , Christopher Holland
IPC分类号： A61K6/083
CPC分类号： A61L27/3687 , A61L27/3604 , C08H1/00 , C08L89/00
摘要： A method for the preparation of a regenerated silk fibroin solution comprises the steps of: treating silk or silk cocoons with an ionic reagent comprising an aqueous solution of monovalent cations and monovalent anions, the cations and anions having ionic radii of at least 1.05 Angstroms and a Jones-Dole B coefficient of between −0.001 and −0.05 at 25° C.; and subsequently degumming the treated silk or silk cocoons; or alternatively, degumming silk or silk cocoons; and subsequently treating the degummed silk or silk cocoons with an ionic reagent comprising an aqueous solution of monovalent cations and monovalent anions, the cations and anions having ionic radii of at least 1.05 Angstroms and a Jones-Dole B coefficient of between −0.001 and −0.05 at 25° C. The invention also extends to fibroin solution, a fibroin material and an implant useful for cartilage repair.
摘要翻译：一种制备再生丝素蛋白溶液的方法包括以下步骤：用包含一价阳离子和一价阴离子的水溶液的离子试剂处理丝或丝茧，所述阳离子和阴离子的离子半径至少为1.05埃， Jones-Dole B系数在25℃在-0.001和-0.05之间。然后使经处理的丝或丝茧脱胶; 或者脱胶丝或丝茧; 并随后用包含一价阳离子和一价阴离子水溶液的离子试剂处理脱胶的丝或丝茧，阳离子和阴离子的离子半径至少为1.05埃，琼斯 - 多尔B系数在-0.001-0.05之间在25℃下。本发明还延伸到丝心蛋白溶液，丝心蛋白材料和用于软骨修复的植入物。

23. 发明申请

US20110177151A1 IMPLANTABLE MATERIAL AND A METHOD FOR THE PREPARATION THEREOF 有权
标题翻译：可植入材料及其制备方法
公开(公告)号：US20110177151A1
公开(公告)日：2011-07-21
申请号：US12990399
申请日：2009-04-30
申请人： David Philip Knight , Nicholas James Vavasour Skaer , Andrew Michael Collins , Tom Louis Dirk Gheysens , Christopher Holland
发明人： David Philip Knight , Nicholas James Vavasour Skaer , Andrew Michael Collins , Tom Louis Dirk Gheysens , Christopher Holland
IPC分类号： A61K38/17 , C12S3/14 , C07K1/00 , A61K9/00 , C07K14/435 , A61P19/04 , A61P19/00
CPC分类号： A61L27/3687 , A61L27/3604 , C08H1/00 , C08L89/00
摘要： A method for the preparation of a regenerated silk fibroin solution comprises the steps of: treating silk or silk cocoons with an ionic reagent comprising an aqueous solution of monovalent cations and monovalent anions, the cations and anions having ionic radii of at least 1.05 Angstroms and a Jones-Dole B coefficient of between −0.001 and −0.05 at 25° C.; and subsequently degumming the treated silk or silk cocoons; or alternatively, degumming silk or silk cocoons; and subsequently treating the degummed silk or silk cocoons with an ionic reagent comprising an aqueous solution of monovalent cations and monovalent anions, the cations and anions having ionic radii of at least 1.05 Angstroms and a Jones-Dole B coefficient of between −0.001 and −0.05 at 25° C. The invention also extends to fibroin solution, a fibroin material and an implant useful for cartilage repair.
摘要翻译：一种制备再生丝素蛋白溶液的方法包括以下步骤：用包含一价阳离子和一价阴离子的水溶液的离子试剂处理丝或丝茧，所述阳离子和阴离子的离子半径至少为1.05埃， Jones-Dole B系数在25℃在-0.001和-0.05之间。然后使经处理的丝或丝茧脱胶; 或者脱胶丝或丝茧; 并随后用包含一价阳离子和一价阴离子水溶液的离子试剂处理脱胶的丝或丝茧，阳离子和阴离子的离子半径至少为1.05埃，琼斯 - 多尔B系数在-0.001-0.05之间在25℃下。本发明还延伸到丝心蛋白溶液，丝心蛋白材料和用于软骨修复的植入物。

24. 发明申请

US20100143034A1 Method and Apparatus for a Roadway Marker 审中-公开
标题翻译：道路标记的方法和装置
公开(公告)号：US20100143034A1
公开(公告)日：2010-06-10
申请号：US12626113
申请日：2009-11-25
申请人： Arra David Yeghiayan , Michael Collins
发明人： Arra David Yeghiayan , Michael Collins
IPC分类号： E01F9/00
CPC分类号： E01F9/627 , E01F9/619 , E01F9/692
摘要： A marker includes a base. The base has a first end, a middle portion and a second end, wherein the middle portion is located between the first end and the second end. A spring element is attached to the middle portion of the base. An elongated rod is attached to the spring element at a first end.
摘要翻译：标记包括基座。基部具有第一端部，中部部分和第二端部，其中中间部分位于第一端部和第二端部之间。弹簧元件连接到基座的中间部分。细长的杆在第一端附接到弹簧元件。

25. 发明授权

US07625187B2 Submersible pump with integrated liquid level sensing and control system 有权
标题翻译：具有集成液位感应和控制系统的潜水泵
公开(公告)号：US07625187B2
公开(公告)日：2009-12-01
申请号：US11210340
申请日：2005-08-24
申请人： Michael Collins , Gerald A. Assessor
发明人： Michael Collins , Gerald A. Assessor
IPC分类号： F04B49/00
CPC分类号： F04D15/0218
摘要： In accordance with one embodiment of the present invention, there is provided a submersible pump that includes a pump housing forming a main compartment for receiving a pump impeller and having liquid entrance and exit openings in said main compartment, and an impeller mounted in the main compartment. The pump housing is adapted for submersion in a body of liquid whose level is to be controlled, and a sealed auxiliary compartment is formed as an integral part of the housing and located to be at least partially submerged in the liquid body. A drive motor is coupled to the impeller for rotating the impeller to eject liquid from the main compartment through the exit opening. An electric-field sensor is mounted in the sealed auxiliary compartment for detecting the elevation of the surface of the liquid body adjacent the sealed auxiliary compartment. At least one controllable switch is connected in the power supply line for controlling the supply of power to the drive motor, and the electric-field sensor is connected to the controllable switch for opening and closing the switch in response to changes in the detected elevation of the surface of the liquid body adjacent the outer surface of the sealed auxiliary compartment.
摘要翻译：根据本发明的一个实施例，提供了一种潜水泵，其包括形成用于接收泵叶轮并在所述主隔室中具有液体入口和出口的主室的泵壳体，以及安装在主室中的叶轮。泵壳体适于浸入液体的主体内，液体的主体将被控制，并且密封的辅助隔室形成为壳体的一体部分并被定位成至少部分地浸没在液体中。驱动马达联接到叶轮上，用于旋转叶轮以通过出口从主隔室喷出液体。电场传感器安装在密封的辅助室中，用于检测与密封的辅助隔室相邻的液体的表面的高度。至少一个可控开关连接在电源线中，用于控制对驱动电机的供电，并且电场传感器连接到可控开关，用于响应于检测到的高程的变化而打开和关闭开关液体的表面与密封辅助隔室的外表面相邻。

26. 发明申请

US20080176993A1 Copolymers of vinyl alcohol and itaconic acid for use in paper coatings 有权
公开(公告)号：US20080176993A1
公开(公告)日：2008-07-24
申请号：US12077308
申请日：2008-03-17
申请人： Elliott Echt , Peter A. Morken , G. Michael Collins
发明人： Elliott Echt , Peter A. Morken , G. Michael Collins
IPC分类号： C08L29/04
CPC分类号： C09D129/04 , D21H19/20 , D21H19/58 , D21H19/60
摘要： The present invention is a composition useful for coating the surface of paper wherein the coating composition is an aqueous solution comprising less than 40 wt % water and consisting essentially of a polyvinyl alcohol copolymer that is at least about 95% hydrolyzed, and a process for preparing the same.

27. 发明申请

US20070228250A1 Decorative article 失效
标题翻译：装饰品
公开(公告)号：US20070228250A1
公开(公告)日：2007-10-04
申请号：US11392859
申请日：2006-03-29
申请人： Theresa Pilutti , Michael Collins
发明人： Theresa Pilutti , Michael Collins
IPC分类号： F16M13/02
CPC分类号： B44C3/12 , B44C5/02
摘要： A multi-functional decorative article having a body and three or more apertures in the body, wherein two or more apertures are continuous with each other within said body, whereby the apertures can be used to support and arrange products, mainly window treatments, in a variety of decorative arrangements; the optional coverings for the apertures can be used to support products and arrange products; and the optional fasteners can be used to fasten products to the body.
摘要翻译：一种多功能装饰品，其具有主体和主体中的三个或更多个孔，其中两个或更多个孔在所述主体内彼此连续，由此所述孔可用于支撑和布置产品，主要是窗口处理各种装饰布置; 孔的可选覆盖物可用于支撑产品并排列产品; 并且可选的紧固件可用于将产品紧固到身体。

28. 发明申请

US20070214235A1 Application server for processing medical image data 审中-公开
标题翻译：用于处理医学图像数据的应用服务器
公开(公告)号：US20070214235A1
公开(公告)日：2007-09-13
申请号：US11414958
申请日：2006-05-01
申请人： Kevin Woods , Ryan McGinnis , Michael Collins
发明人： Kevin Woods , Ryan McGinnis , Michael Collins
IPC分类号： G06F15/16
CPC分类号： G06F19/321
摘要： A method and system for sharing intermediate medical image processing results among several different applications is disclosed. An application server serves as mediator between a medical image database storage, image processing applications, and a workstation display resident on a computer network. The application server polices the intermediate processing results from several different image processing applications in order for the image processing applications to share their intermediate results. By sharing the intermediate results, the application server helps to eliminate duplicate processing and inconsistent results between the image processing applications. The final image processing results are either stored on the medical image database or displayed on the workstation as needed. The image processing applications could reside on the application server or on their own separate networked computer. Alternatively, some image processing applications could reside on the application server and some on separate networked computers.
摘要翻译：公开了在不同应用中共享中间医疗图像处理结果的方法和系统。应用服务器用作医疗图像数据库存储器，图像处理应用程序和驻留在计算机网络上的工作站显示器之间的中介器。应用服务器对来自多个不同图像处理应用程序的中间处理结果进行策略处理，以使图像处理应用程序共享其中间结果。通过共享中间结果，应用服务器有助于消除图像处理应用程序之间的重复处理和不一致的结果。最终的图像处理结果存储在医学图像数据库上，或者根据需要显示在工作站上。图像处理应用程序可以驻留在应用程序服务器或其自己的独立联网计算机上。或者，一些图像处理应用可以驻留在应用服务器上，一些可以驻留在单独的联网计算机上。

29. 发明申请

US20070015717A1 4-[(E)-2-(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPTHALENYL)-1-PROPENYL]BENZOIC ACID ANALOGS AND METHOD OF MANUFACTURE AND USE THEREOF 有权
标题翻译： 4 - [（E）-2-（5,6,7,8-四氢-5,5,8,8-四巯基-2-氮萘基）-1-丙烯]苯甲酸类似物及其制备和使用方法
公开(公告)号：US20070015717A1
公开(公告)日：2007-01-18
申请号：US11428165
申请日：2006-06-30
申请人： Robert Curley , Margaret Clagett-Dame , Michael Collins , Victoria Abzianidze
发明人： Robert Curley , Margaret Clagett-Dame , Michael Collins , Victoria Abzianidze
IPC分类号： A61K31/7034 , C07H15/04
CPC分类号： C07C233/75 , C07C49/798 , C07C49/835 , C07C49/84 , C07C2602/10 , C07H7/02 , C07H15/04 , C07H15/203
摘要： Analogs of 4-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-napthalenyl)-1-propenyl]benzoic acid and methods of manufacture and use thereof, such as for use in cancer prevention and treatment.
摘要翻译： 4 - [（E）-2-（5,6,7,8-四氢-5,5,8,8-四甲基-2-萘基）-1-丙烯基]苯甲酸的类似物及其制备和使用方法，例如用于癌症预防和治疗。

30. 发明申请

US20060263900A1 Method and apparatus for rapid fat content determination 有权
公开(公告)号：US20060263900A1
公开(公告)日：2006-11-23
申请号：US11486678
申请日：2006-07-14
申请人： Michael Collins , Edward King
发明人： Michael Collins , Edward King
IPC分类号： G01N24/00
CPC分类号： G01N24/08 , G01N1/44 , G01N5/04 , G01N24/081 , G01N24/085 , G01N33/06 , G01R33/44
摘要： A method and apparatus for rapidly and accurately determining the fat and oil content of a sample using microwave drying and NMR analysis is disclosed. The method and apparatus incorporate a low mass, porous, hydrophilic and lipophilic sample pad that ensures that the entire sample is subjected to NMR analysis. The method and apparatus according to the invention are suitable for rapidly determining the fat and oil content of samples collected during a production process and for process or quality control.

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