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21. 发明授权

US1433457A Camp cot 失效
标题翻译：营地婴儿床
公开(公告)号：US1433457A
公开(公告)日：1922-10-24
申请号：US54135622
申请日：1922-03-06
申请人： JOSEPH HUNTER
发明人： JOSEPH HUNTER
IPC分类号： A47C17/64
CPC分类号： A47C17/64

22. 发明申请

US20210027241A1 INTEGRATED PLATFORM FOR PROGRAMMATIC INTERACTIONS FOR TRANSPORTATION SERVICES 有权
公开(公告)号：US20210027241A1
公开(公告)日：2021-01-28
申请号：US16936661
申请日：2020-07-23
申请人： Joseph Hunter Burke
发明人： Joseph Hunter Burke
IPC分类号： G06Q10/08 , G06N20/00
摘要： Various embodiments further provide techniques for performing predictive data analysis using non-persistent-input machine learning models. Various embodiments provide techniques related to a platform for matching loads to carriers, such as techniques related to performing predictive data analysis tasks on the noted platform, including techniques for performing predictive data analysis using non-persistent-input machine learning models. In one example, a method includes generating the non-persistent-input machine learning model based on a persistently updated training data object and a joined periodic data object, where the joined periodic data object is determined by retrieving a plurality of periodically updated data objects from the plurality of periodically updated data sources, performing an aggregate join operation across the plurality of periodically updated data objects to generate an updated joined periodic data object, and updating a joined periodic data object in a storage medium based on the updated joined periodic data object.

23. 发明申请

US20120263657A1 Promoting Whole Body Health 审中-公开
标题翻译：促进全身健康
公开(公告)号：US20120263657A1
公开(公告)日：2012-10-18
申请号：US13532861
申请日：2012-06-26
申请人： Matthew Joseph Doyle , Stephen Joseph Hunter-Rinderle
发明人： Matthew Joseph Doyle , Stephen Joseph Hunter-Rinderle
IPC分类号： A61K31/4425 , A61K33/16 , A61K33/20 , A61P31/04 , A61K33/40 , A61P25/00 , A61P9/00 , A61P9/10 , A61P3/10 , A61P11/00 , A61P15/00 , A61K31/14 , A61K33/24
CPC分类号： A61K8/347 , A61K8/416 , A61K8/43 , A61K8/49 , A61K8/4926 , A61K9/006 , A61K9/08 , A61K31/05 , A61K31/14 , A61K31/155 , A61K31/17 , A61K31/315 , A61K31/44 , A61K31/4425 , A61K31/4745 , A61K33/00 , A61K33/16 , A61K33/24 , A61K33/30 , A61K33/34 , A61K33/40 , A61K45/06 , A61Q11/00 , A61K2300/00
摘要： Disclosed are topical oral compositions comprising a safe and effective amount of an antimicrobial agent in admixture with a pharmaceutically acceptable carrier, the compositions being effective in controlling bacterial-mediated diseases and conditions present in the oral cavity and in inhibiting the spread into the bloodstream of pathogenic oral bacteria, associated bacterial toxins and endotoxins, and resultant inflammatory cytokines and mediators. Also disclosed are methods of use of these topical antimicrobial oral compositions to reduce the risk of developing an oral bacteria-induced systemic disease and to promote whole body health in humans and other animals.
摘要翻译：公开了包含与药学上可接受的载体混合的安全有效量的抗微生物剂的局部口服组合物，所述组合物有效地控制存在于口腔中的细菌介导的疾病和病症并抑制扩散到病原体的血液中口服细菌，相关细菌毒素和内毒素，以及产生的炎性细胞因子和介质。还公开了使用这些局部抗微生物口服组合物以降低口腔细菌诱发的全身性疾病和促进人和其他动物的全身健康的风险的方法。

24. 发明申请

US20090269350A1 Novel 27411, 23413, 22438, 23553, 25278, 26212, NARC SC1, NARC 10A, NARC 1, NARC 12, NARC 13, NARC17, NARC 25, NARC 3, NARC 4, NARC 7, NARC 8, NARC 11, NARC 14A, NARC 15, NARC 16, NARC 19, NARC 20, NARC 26, NARC 27, NARC 28, NARC 30, NARC 5, NARC 6, NARC 9, NARC 10C, NARC 8B, NARC 9, NARC2A, NARC 16B, NARC1C, NARC 1A, NARC 25, 86604 and 32222 molecules and uses therefor 失效
标题翻译：新的27411,23413,22438,23553,25278,26212，NARC SC1，NARC 10A，NARC 1，NARC 12，NARC 13，NARC 17，NARC 25，NARC 3，NARC 4，NARC 7，NARC 8，NARC 11，NARC 14A ，NARC 15，NARC 16，NARC 19，NARC 20，NARC 26，NARC 27，NARC 28，NARC 30，NARC 5，NARC 6，NARC 9，NARC 10C，NARC 8B，NARC 9，NARC2A，NARC 16B，NARC1C， NARC 1A，NARC 25,86604和32222分子及其用途
公开(公告)号：US20090269350A1
公开(公告)日：2009-10-29
申请号：US12316681
申请日：2008-12-16
申请人： Maria A. Glucksmann , Mark J. Williamson , Fong-Ying Tsai , Laura A. Rudolph-Owen , Rosanna Kapeller-Libermann , Rachel E. Meyers , Lillian Wei-Ming Chiang , John Joseph Hunter
发明人： Maria A. Glucksmann , Mark J. Williamson , Fong-Ying Tsai , Laura A. Rudolph-Owen , Rosanna Kapeller-Libermann , Rachel E. Meyers , Lillian Wei-Ming Chiang , John Joseph Hunter
IPC分类号： A61K39/395 , C07H21/04 , C12N5/00 , C07K14/00 , C07K16/00 , C12P21/06 , C12Q1/68 , G01N33/53 , A61K31/7088 , A61K38/16
CPC分类号： C12N9/1288 , A01K2217/05 , A61K38/00 , A61K47/6805 , A61K47/6809 , A61K47/6821 , A61K48/00 , A61K2039/505 , C07K14/4747 , C07K2319/00 , C12N9/14 , C12N9/16 , C12N9/6472 , G01N33/5011 , G01N33/57407 , G01N33/57484 , G01N2500/10
摘要： The invention provides isolated nucleic acids molecules and proteins, designated 27411, 23413, 22438, 23553, 25278, 26212, NARC SC1, NARC 20A, NARC 1, NARC 12, NARC 13, NARC17, NARC 25, NARC 3, NARC 4, NARC 7, NARC 8, NARC 11, NARC 14A, NARC 15, NARC 16, NARC 19, NARC 20, NARC 26, NARC 27, NARC 28, NARC 30, NARC 5, NARC 6, NARC 9, NARC 10C, NARC 8B, NARC 9, NARC2A, NARC 16B, NARC 1C, NARC 1A, NARC 25, 86604 and 32222 nucleic acid molecules and proteins. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing said nucleic acid molecules, host cells into which the expression vectors have been introduced, nonhuman transgenic animals in which a said genes have been introduced or disrupted, fusion proteins, antigenic peptides and antibodies to said proteins. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供分离的核酸分子和蛋白质，命名为27411,23413,22438,23553,25278,26212，NARC SC1，NARC 20A，NARC 1，NARC 12，NARC 13，NARC 17，NARC 25，NARC 3，NARC 4，NARC 7，NARC 8，NARC 11，NARC 14A，NARC 15，NARC 16，NARC 19，NARC 20，NARC 26，NARC 27，NARC 28，NARC 30，NARC 5，NARC 6，NARC 9，NARC 10C，NARC 8B， NARC 9，NARC2A，NARC 16B，NARC 1C，NARC 1A，NARC 25，86604和32222核酸分子和蛋白质。本发明还提供了反义核酸分子，含有所述核酸分子的重组表达载体，其中引入了表达载体的宿主细胞，其中所述基因已导入或破坏的非人类转基因动物，融合蛋白，抗原肽和抗体到蛋白质。还提供了利用本发明组合物的诊断和治疗方法。

25. 发明授权

US06846478B1 Promoting whole body health 失效
标题翻译：促进全身健康
公开(公告)号：US06846478B1
公开(公告)日：2005-01-25
申请号：US09607729
申请日：2000-06-30
申请人： Matthew Joseph Doyle , Stephen Joseph Hunter-Rinderle , Robert Ernest Singer, Jr. , Rohan Lalith Wimalasena
发明人： Matthew Joseph Doyle , Stephen Joseph Hunter-Rinderle , Robert Ernest Singer, Jr. , Rohan Lalith Wimalasena
IPC分类号： A61K8/00 , A61K8/20 , A61K8/36 , A61K8/40 , A61K8/41 , A61K8/42 , A61K8/44 , A61K8/49 , A61K8/64 , A61K8/66 , A61K33/20 , A61Q11/00 , A61K7/16
CPC分类号： A61K8/20 , A61K33/20 , A61Q11/00
摘要： The present invention relates to promoting whole body health in humans and animals by using topical oral compositions comprising a safe and effective amount of chlorite ion in admixture with a pharmaceutically acceptable carrier, said compositions being effective in controlling bacterial-mediated diseases and conditions present in the oral cavity and inhibiting the spread into the bloodstream of oral pathogenic bacteria and associated bacterial toxins and resultant inflammatory cytokines and mediators. The present invention also encompasses methods of use of these compositions by topically applying to the oral cavity, a safe and effective amount of chlorite ion to promote and/or enhance whole body health in humans and other animals.
摘要翻译：本发明涉及通过使用包含安全有效量的亚氯酸根离子与药学上可接受的载体混合的局部口服组合物来促进人和动物的全身健康，所述组合物有效地控制细菌介导的疾病和病症口腔和抑制口腔病原菌和相关细菌毒素和所产生的炎性细胞因子和介质的血液中的扩散。本发明还包括通过局部施用于口腔，安全有效量的亚氯酸根离子来促进和/或增强人和其他动物的全身健康的方法来使用这些组合物。

26. 发明授权

US07214502B2 3714, 16742, 23546, and 13887 novel protein kinase molecules and uses therefor 有权
标题翻译： 3714,16742,23546和13887新型蛋白激酶分子及其用途
公开(公告)号：US07214502B2
公开(公告)日：2007-05-08
申请号：US10393316
申请日：2003-03-20
申请人： Rachel Meyers , John Joseph Hunter
发明人： Rachel Meyers , John Joseph Hunter
IPC分类号： C12Q1/48 , C12N9/12
CPC分类号： C12N9/1205 , C12Q1/48 , C12Q1/6886 , C12Q2600/106 , C12Q2600/136 , C12Q2600/156
摘要： The invention provides isolated nucleic acids molecules, designated 3714, 16742, 23546, or 13887 nucleic acid molecules, which encode novel protein kinases. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 3714, 16742, 23546, or 13887 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 3714, 16742, 23546, or 13887 gene has been introduced or disrupted. The invention sill further provides isolated 3714, 16742, 23546, or 13887 proteins, fusion proteins, antigenic peptides and anti-3714, -16742, -23546, or -13887 antibodies. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供编码新的蛋白激酶的分离的核酸分子，命名为3714,16742,23546或13887核酸分子。本发明还提供反义核酸分子，含有3714,16742,23546或13887核酸分子的重组表达载体，已经引入表达载体的宿主细胞，以及非人类转基因动物，其中3714,16742,23546或 13887基因已被引入或破坏。本发明进一步提供分离的3714,16742,23546或13887蛋白，融合蛋白，抗原肽和抗-3714，-16742，-23546或-13887抗体。还提供了利用本发明组合物的诊断，筛选和治疗方法。

27. 发明申请

US20070039488A1 Oven 失效
标题翻译：烤箱
公开(公告)号：US20070039488A1
公开(公告)日：2007-02-22
申请号：US10570773
申请日：2004-09-03
申请人： Joseph Hunter , Andrew Kulka
发明人： Joseph Hunter , Andrew Kulka
IPC分类号： A23B4/03
CPC分类号： F24C15/164 , A47J37/042 , F24C15/327
摘要： A dual-mode oven (40) which is capable of being used in a rotisserie mode or in a convection mode, the oven comprising heater means (8) and fan means (7), the heater means and the fan means being located at the top of the oven cavity (43), in use, the fan means forces air across the heater means and into the cooking space through adjustable heated air outlets (46). In a rotisserie mode the heated air outlets are inwardly directed towards food to be cooked, and in a convection mode the heated air outlets are outwardly directed so as to distribute heated air evenly throughout the cooking space.
摘要翻译：一种双模式烤箱（40），其能够以旋转烤架模式或对流模式使用，烤箱包括加热器装置（8）和风扇装置（7），加热器装置和风扇装置位于在使用中，风扇装置（43）的顶部通过可调节的加热空气出口（46）迫使空气穿过加热器装置进入烹饪空间。在旋转烤架模式中，加热的空气出口向内指向要烹饪的食物，并且在对流模式中，加热的空气出口向外指向，以将热空气均匀地分布在烹饪空间中。

28. 发明授权

US07166428B2 62112, a novel human dehydrogenase and uses thereof 失效
标题翻译： 62112，一种新的人脱氢酶及其用途
公开(公告)号：US07166428B2
公开(公告)日：2007-01-23
申请号：US09945326
申请日：2001-08-31
申请人： Rachel Meyers , John Joseph Hunter
发明人： Rachel Meyers , John Joseph Hunter
IPC分类号： C12Q1/68
CPC分类号： C12N9/001 , A61K38/00 , C07K2319/00
摘要： The invention provides isolated nucleic acids molecules, designated DHDR-7 nucleic acid molecules, which encode novel human dehydrogenase molecules. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing DHDR-7 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a DHDR-7 gene has been introduced or disrupted. The invention still further provides isolated DHDR-7 polypeptides, fusion polypeptides, antigenic peptides and anti-DHDR-7 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
摘要翻译：本发明提供编码新的人脱氢酶分子的分离的核酸分子，命名为DHDR-7核酸分子。本发明还提供了反义核酸分子，含有DHDR-7核酸分子的重组表达载体，其中引入了表达载体的宿主细胞，以及DHDR-7基因导入或破坏的非人类转基因动物。本发明还进一步提供了分离的DHDR-7多肽，融合多肽，抗原肽和抗DHDR-7抗体。还提供利用本发明组合物的诊断方法。

29. 发明申请

US20060040842A1 Fabric treatment compositions 审中-公开
标题翻译：织物处理组合物
公开(公告)号：US20060040842A1
公开(公告)日：2006-02-23
申请号：US11258331
申请日：2005-10-25
申请人： Paul Findlay , Joseph Hunter , Laxmikant Tiwari , Nicola Whilton
发明人： Paul Findlay , Joseph Hunter , Laxmikant Tiwari , Nicola Whilton
IPC分类号： C11D3/12
CPC分类号： C11D3/1253 , C01B33/44 , C11D3/1226
摘要： Fabric treatment compositions comprising a textile compatible carrier and particles having a layered structure comprising oxygen atoms and silicon and/or phosphorus atoms and comprising organic functional groups which are bonded to silicon and/or phosphorus atoms by direct covalent bonds between the silicon and/or phosphorus atoms and a carbon atom. The functional groups are selected to impart lubricating properties to the particles.
摘要翻译：包含纺织物相容性载体的织物处理组合物和包含氧原子和硅和/或磷原子的层状结构的颗粒，并且包含通过硅和/或磷之间的直接共价键与硅和/或磷原子键合的有机官能团原子和碳原子。选择官能团以赋予颗粒润滑性能。

30. 发明授权

US06451994B1 23413, a novel human ubiquitin protease 失效
标题翻译： 23413，一种新型人类泛素蛋白酶
公开(公告)号：US06451994B1
公开(公告)日：2002-09-17
申请号：US09406045
申请日：1999-09-27
申请人： Rosana Kapeller-Libermann , John Joseph Hunter
发明人： Rosana Kapeller-Libermann , John Joseph Hunter
IPC分类号： C07H2102
CPC分类号： C12N9/6472 , A01K2217/05 , A61K38/00 , A61K48/00
摘要： The present invention relates to a newly identified human ubiquitin protease belonging to the family of mammalian deubiquitinating enzymes. The invention also relates to polynucleotides encoding the ubiquitin protease. The invention further relates to methods using the ubiquitin protease polypeptides and polynucleotides as a target for diagnosis and treatment in ubiquitin-mediated or -related disorders. The invention further relates to drug-screening methods using the ubiquitin protease polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the ubiquitin protease polypeptides and polynucleotides. The invention further relates to procedures for producing the ubiquitin protease polypeptides and polynucleotides.
摘要翻译：本发明涉及属于哺乳动物脱蛋白酶家族的新鉴定的人泛素蛋白酶。本发明还涉及编码泛素蛋白酶的多核苷酸。本发明还涉及使用泛素蛋白酶多肽和多核苷酸作为在泛素介导的或相关疾病中进行诊断和治疗的靶标的方法。本发明还涉及使用泛素蛋白酶多肽和多核苷酸鉴定用于诊断和治疗的激动剂和拮抗剂的药物筛选方法。本发明还包括基于泛素蛋白酶多肽和多核苷酸的激动剂和拮抗剂。本发明还涉及生产泛素蛋白酶多肽和多核苷酸的方法。

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