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21. 外观设计

USD797918S1 Medical device control unit 有权
公开(公告)号：USD797918S1
公开(公告)日：2017-09-19
申请号：US29503033
申请日：2014-09-22
申请人： EKOS CORPORATION
设计人： Curtis Genstler , William Russell Kanz , Michael George Svob , William Lyle Richardson , Jeff Ladwig , Amy Brumet , Eric Wahl , David Kalamen , Stephanie Seraphina , Alex Hay

22. 外观设计

USD794662S1 Medical device control unit display screen with graphical user interface 有权
公开(公告)号：USD794662S1
公开(公告)日：2017-08-15
申请号：US29503035
申请日：2014-09-22
申请人： EKOS CORPORATION
设计人： Curtis Genstler , William Russell Kanz , Michael George Svob , William Lyle Richardson , Jeff Ladwig , Amy Brumet , Eric Wahl , David Kalamen , Stephanie Seraphina , Alex Hay

23. 发明申请

US20120289889A1 ULTRASOUND SYSTEM 审中-公开
标题翻译：超声系统
公开(公告)号：US20120289889A1
公开(公告)日：2012-11-15
申请号：US13468920
申请日：2012-05-10
申请人： Curtis Genstler , Douglas R. Hansmann
发明人： Curtis Genstler , Douglas R. Hansmann
IPC分类号： A61M37/00
摘要： A catheter system for delivering ultrasonic energy to a treatment site within a body lumen, the catheter comprises a tubular body having a proximal end, a distal end and an energy delivery section positioned between the proximal end and the distal end and a plurality of ultrasound radiating members in the energy delivery section. The plurality of ultrasound radiating members are allocated into electrical groups comprising more than one ultrasound radiating member. Members of one electrical group are spatially interdigitated with members of another electrical group.
摘要翻译：一种用于将超声能量输送到体腔内的治疗部位的导管系统，所述导管包括管状体，所述管状体具有近端，远端和位于所述近端和远端之间的能量输送部分，以及多个超声辐射能源交付部门的成员。多个超声波辐射构件被分配成包括多于一个的超声波辐射构件的电组。一个电气组的成员与另一个电气组的成员在空间上相互交错。

24. 发明申请

US20120271203A1 POWER PARAMETERS FOR ULTRASONIC CATHETER 有权
标题翻译：超声波电源的功率参数
公开(公告)号：US20120271203A1
公开(公告)日：2012-10-25
申请号：US13454983
申请日：2012-04-24
申请人： Azita Soltani , Kim R. Volz
发明人： Azita Soltani , Kim R. Volz
IPC分类号： A61N7/00 , A61M25/00
CPC分类号： A61M37/0092 , A61B17/22004 , A61B17/2202 , A61B2017/00084 , A61B2017/00088 , A61B2017/00092 , A61B2017/22008 , A61B2017/22084 , A61B2018/0041 , A61B2018/00642 , A61B2018/00702 , A61B2018/00791 , A61N7/022 , A61N2007/0039 , A61N2007/0078
摘要： An ultrasound catheter system and a method for operating an ultrasonic catheter at a treatment site within a patient's vasculature or tissue are disclosed. The ultrasound catheter system comprises a catheter having at least one ultrasonic element and a control system configured to generate power parameters that drive the at least one ultrasonic element to generate ultrasonic energy. The control system is configured to vary at least one of the power parameters and at least one physiological parameter by repeatedly cycling the power parameter and the physiological parameter through two set of values.
摘要翻译：公开了一种超声波导管系统和用于在患者的脉管系统或组织内的治疗部位操作超声波导管的方法。超声导管系统包括具有至少一个超声波元件和被配置为产生驱动该至少一个超声波元件以产生超声波能量的功率参数的控制系统的导管。控制系统被配置为通过两组值重复循环功率参数和生理参数来改变功率参数和至少一个生理参数中的至少一个。

25. 发明授权

US08226629B1 Ultrasonic catheter power control 有权
标题翻译：超声波导管功率控制
公开(公告)号：US08226629B1
公开(公告)日：2012-07-24
申请号：US12415965
申请日：2009-03-31
申请人： George Keilman , Douglas R. Hansmann , Azita Soltani , Richard R. Wilson
发明人： George Keilman , Douglas R. Hansmann , Azita Soltani , Richard R. Wilson
IPC分类号： A61M31/00
CPC分类号： A61M37/0092 , A61B17/320068
摘要： A method of treating an occlusion at a treatment site within a patient's vasculature comprises providing an ultrasonic catheter. The ultrasonic catheter has a distal region, a proximal region opposite the distal region, a fluid delivery lumen having at least one opening in the distal region, and an ultrasound radiating member positioned within the distal region. The method further comprises positioning the ultrasonic catheter at the treatment site, such that at least a portion of the distal region is within the occlusion. The ultrasonic catheter further comprises passing a therapeutic compound through the fluid delivery lumen such that the therapeutic compound is delivered to the treatment site. The ultrasonic catheter further comprises emitting ultrasonic energy from the ultrasound radiating member. The emitted ultrasonic energy has an amplitude that is periodically varied between a low amplitude and a high amplitude.
摘要翻译：治疗患者脉管系统内的治疗部位的闭塞的方法包括提供超声导管。超声波导管具有远端区域，与远端区域相对的近端区域，具有在远侧区域中的至少一个开口的流体输送腔和位于远侧区域内的超声波辐射构件。该方法还包括将超声波导管定位在治疗部位，使得远侧区域的至少一部分在咬合内。超声波导管还包括使治疗化合物通过流体输送腔，使得治疗化合物被递送至治疗部位。超声波导管还包括从超声波辐射构件发射超声波能量。发射的超声能量具有在低振幅和高振幅之间周期性变化的幅度。

26. 发明授权

US07774933B2 Method of manufacturing ultrasound catheters 有权
标题翻译：制造超声导管的方法
公开(公告)号：US07774933B2
公开(公告)日：2010-08-17
申请号：US11417384
申请日：2006-05-04
申请人： Richard R. Wilson , Tim Abrahamson , Leonard R. Oliver
发明人： Richard R. Wilson , Tim Abrahamson , Leonard R. Oliver
IPC分类号： H01R43/00 , H05K13/00
CPC分类号： A61B17/2202 , A61B8/12 , A61B17/22 , A61B2017/00084 , A61B2017/22021 , A61B2017/22082 , A61B2017/22088 , B29C63/42 , Y10T29/49007 , Y10T29/49117 , Y10T29/49169 , Y10T29/49826
摘要： An ultrasonic catheter is manufactured by providing an inner tube having an inner diameter sufficient to accommodate a guidewire, and mounting a tubular ultrasound radiating member around a distal region of the inner tube. Two electrical conductors are positioned along the inner tube, such that one of the electrical conductors contacts an inner side of the ultrasound radiating member while the other electrical conductor contacts an outer side of the ultrasound radiating member. An outer tube is then concentrically translated over the inner tube and the ultrasound radiating member, and radially shrunken onto the inner tube.
摘要翻译：通过提供具有足以容纳导丝的内径的内管并且围绕内管的远侧区域安装管状超声波辐射构件来制造超声波导管。两个电导体沿着内管定位，使得一个电导体接触超声波辐射构件的内侧，而另一个电导体接触超声波辐射构件的外侧。然后将外管在内管和超声波辐射构件上同心地平移，并且径向缩小到内管上。

27. 发明授权

US07727178B2 Catheter with multiple ultrasound radiating members 有权
公开(公告)号：US07727178B2
公开(公告)日：2010-06-01
申请号：US11643471
申请日：2006-12-21
申请人： Richard R. Wilson , Robert L. Wilcox , Curtis Genstler , Tim Abrahamson , Wm. Gerrit Barrere , Amy Cohen , George Keilman , Leonard R. Oliver , Natalya Peskin
发明人： Richard R. Wilson , Robert L. Wilcox , Curtis Genstler , Tim Abrahamson , Wm. Gerrit Barrere , Amy Cohen , George Keilman , Leonard R. Oliver , Natalya Peskin
IPC分类号： A61B17/20
CPC分类号： A61M37/0092 , A61B17/2202 , A61B2017/22084 , A61B2017/22088 , A61M25/0029 , A61M25/0032 , A61N7/00 , A61N2007/0078
摘要： A catheter for delivering ultrasonic energy and therapeutic compounds to a treatment site within a patient's vasculature comprises a tubular body. The tubular body has a proximal region and a distal region opposite the proximal region. The catheter further comprises a plurality of fluid delivery lumens formed into the tubular body. The catheter further comprises an inner core configured for insertion into the tubular body. The inner core comprises an elongate electrical conductor having a plurality of flattened regions, each flattened region having a first flat side and a second flat side opposite the first flat side. The inner core further comprises a plurality of ultrasound radiating members mounted in pairs to the flattened regions of the elongate electrical conductor. A first ultrasound radiating member is mounted to the first flat side of the elongate electrical conductor, and a second ultrasound radiating member is mounted to the second flat side of the elongate electrical conductor. The catheter further comprises control electronics configured to apply a driving signal to at least two, but fewer than all, of the ultrasound radiating members.

28. 发明申请

US20080171965A1 POWER PARAMETERS FOR ULTRASONIC CATHETER 审中-公开
标题翻译：超声波电源的功率参数
公开(公告)号：US20080171965A1
公开(公告)日：2008-07-17
申请号：US11971172
申请日：2008-01-08
申请人： Azita Soltani , Kim R. Volz
发明人： Azita Soltani , Kim R. Volz
IPC分类号： A61N7/00 , A61B17/22
CPC分类号： A61B17/2202 , A61B2017/00181 , A61B2017/00185 , A61B2017/0019 , A61B2017/00194
摘要： In one embodiment of the present invention, a method of applying ultrasonic energy to a treatment site within a patient's vasculature comprises positioning an ultrasound radiating member at a treatment site within a patient's vasculature. The method further comprises activating the ultrasound radiating member to produce pulses of ultrasonic energy at a cycle period T≦1 second. The acoustic parameters such as peak power, pulse width, pulse repetition frequency and frequency or any combination of them can be varied non-linearly.
摘要翻译：在本发明的一个实施例中，将超声能量施加到患者脉管系统内的治疗部位的方法包括将超声波辐射构件定位在患者脉管系统内的治疗部位。该方法还包括激活超声波辐射构件以在循环周期T 1 = 1秒产生超声能量的脉冲。诸如峰值功率，脉冲宽度，脉冲重复频率和频率的声学参数或它们的任何组合可以非线性地改变。

29. 发明申请

US20070265560A1 Ultrasound Therapy System 审中-公开
标题翻译：超声治疗系统
公开(公告)号：US20070265560A1
公开(公告)日：2007-11-15
申请号：US11739629
申请日：2007-04-24
申请人： Azita Soltani , Adrian Prokop
发明人： Azita Soltani , Adrian Prokop
IPC分类号： A61N7/00
CPC分类号： A61N7/022 , A61B17/2202 , A61B2017/22088 , A61B2017/22089 , A61M25/003 , A61M25/0032 , A61M37/0092 , Y10T29/49826
摘要： In one embodiment of the present invention, a system for treating an occlusion within a patient's vasculature with ultrasonic energy comprises a catheter configured to be passed through the patient's vasculature such that a portion of the catheter is positioned at an intravascular treatment site. The system further comprises an ultrasound radiating member, an ultrasound signal generator configured to supply a drive signal to the ultrasound radiating member, an infusion pump configured to pump a therapeutic compound into the fluid delivery lumen so as to cause the therapeutic compound to be delivered to the treatment site and a controller configured to control the ultrasound signal generator and the infusion pump.
摘要翻译：在本发明的一个实施例中，用超声能量治疗患者脉管系统内的闭塞的系统包括构造成穿过患者脉管系统的导管，使得导管的一部分位于血管内治疗部位。该系统还包括超声波辐射构件，被配置为向超声波辐射构件提供驱动信号的超声波信号发生器，配置成将治疗化合物泵送到流体输送腔中的输液泵，以使治疗化合物被输送到所述治疗部位和配置成控制所述超声信号发生器和所述输液泵的控制器。

30. 发明授权

US07201737B2 Treatment of vascular occlusions using elevated temperatures 有权
标题翻译：使用升高的温度治疗血管闭塞
公开(公告)号：US07201737B2
公开(公告)日：2007-04-10
申请号：US11046209
申请日：2005-01-28
申请人： Douglas R. Hansmann , Peter R. Rule
发明人： Douglas R. Hansmann , Peter R. Rule
IPC分类号： A61F7/12
CPC分类号： A61B17/2202 , A61B2018/046
摘要： A method for providing a therapeutic effect to a treatment site within a patient's vasculature comprises positioning a catheter at the treatment site. The catheter includes a heating element and a fluid delivery lumen that is coupled to an exit port within a distal region of the catheter. The method further comprises passing the therapeutic compound through the delivery lumen and the exit port at a flow rate. The heated therapeutic compound is provided to the treatment site. The method further comprises exposing at least a portion of the treatment site and at least a portion of the delivered heated therapeutic compound to ultrasonic energy generated by the ultrasound radiating member.
摘要翻译：用于向患者的脉管系统内的治疗部位提供治疗效果的方法包括将导管定位在治疗部位。导管包括加热元件和流体输送腔，其与导管的远侧区域内的出口连接。该方法还包括以流速使治疗化合物通过输送腔和出口。将加热的治疗化合物提供给治疗部位。所述方法还包括将所述处理部位的至少一部分和所递送的加热治疗化合物的至少一部分暴露于由所述超声波辐射部件产生的超声波能量。

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