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    • 193. 发明申请
    • THERMAL CYCLING USING PHASE CHANGING FLUIDS
    • 使用相变流体的热循环
    • US20130137105A1
    • 2013-05-30
    • US13687768
    • 2012-11-28
    • Rui Zhang
    • Rui Zhang
    • C12P19/34B01L7/00
    • C12P19/34B01L7/52B01L2300/0829B01L2300/1855C12Q1/68F28D20/028G01N21/75
    • The invention provides systems, devices, and methods for heating and cooling chemical or biological samples, such as genetic materials during Polymerase Chain Reaction (“PCR”). The systems, devices, and methods comprise use of a fluid that performs repeated heating and cooling cycles, e.g., ‘thermal cycling’, on sample reactants with a phase changing fluid during evaporation and condensation. The systems, devices, and methods eliminate the need for a heating block as a means to obtain fast and uniform thermal cycling. The disclosure also describes the use of an optical system in conjunction with the thermodynamic cycler for real-time detection. Ultimately, uniformity and speed of the thermodynamic cycler provides for higher sensitivity and throughput of gene replication and detection.
    • 本发明提供用于在聚合酶链式反应(“PCR”)期间加热和冷却化学或生物样品例如遗传物质的系统,装置和方法。 系统,装置和方法包括使用在蒸发和冷凝期间用相变流体对样品反应物进行反复加热和冷却循环(例如“热循环”)的流体。 系统,装置和方法不需要加热块作为获得快速和均匀的热循环的手段。 本公开还描述了与热力学循环仪结合使用光学系统用于实时检测。 最终,热力学循环仪的均匀性和速度提供了基因复制和检测的更高灵敏度和通量。
    • 194. 发明申请
    • Heated food sachet
    • 加热食品香囊
    • US20130037016A1
    • 2013-02-14
    • US13136732
    • 2011-08-10
    • Mark Munguia
    • Mark Munguia
    • A47J36/28F24J1/00
    • B65D81/3484F28D20/028Y02E60/145
    • A heated food sachet (10), sealed on all sides, that may be filled with one or more condiments or other edible substances (11), that contains a heat pack (12), which may be filled with a supercooled solution (13) and that contains a trigger (14). This trigger comprises two parts. First, the trigger may be one or more breakable hollow capsules (FIG. 3) or one or more air pockets (FIG. 4) that may be attached or unattached to the heat pack. Secondly, the inner part of the capsule or air pocket may contain crystals or any other substance (15) that will start the solidification process of the supercooled solution when coming into contact with each other. The heat emitted by the reaction warms the condiments or other edible substances contained in the sachet.
    • 一种加热的食品袋(10),其可以填充有可以填充有过冷溶液(13)的一个或多个调味品或其它可食用物质(11),其包含热包装(12) 并包含触发器(14)。 该触发器包括两部分。 首先,触发器可以是一个或多个可破裂的中空胶囊(图3)或一个或多个气囊(图4),其可附接或未附接到热包。 其次,胶囊或气袋的内部可能含有晶体或任何其他物质(15),当物质接触时,其将开始过冷溶液的凝固过程。 反应产生的热量加热了香囊中含有的调味品或其他可食用物质。