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11. 发明申请

US20180303781A1 Oral Microbiota Promoting Composition 审中-公开
公开(公告)号：US20180303781A1
公开(公告)日：2018-10-25
申请号：US15706177
申请日：2017-09-15
申请人： Knoze Jr. Corporation
发明人： Shunsheng Han
IPC分类号： A61K31/198 , A61K31/719 , A61K9/00 , A61K31/702 , A61K31/7016 , A61K31/7004 , A61K35/00
CPC分类号： A61K31/198 , A23L33/175 , A61K9/0056 , A61K31/7004 , A61K31/7016 , A61K31/702 , A61K31/719 , A61K35/741 , A61K35/744 , A61K2035/115 , A61K2300/00
摘要： A composition useful for promoting a desired oral microbiota to treat an allergy related respiratory condition in a subject in need of such treatment, the composition including an amino acid containing ingredient including individual molecules of L-arginine; the composition in a configuration to be maintained within the oral cavity for a period of at least about 30 seconds to about an hour, the desired oral microbiota including Veillonella and Streptococcus.

12. 发明授权

US08685943B2 Methods for reducing diarrhea in a companion animal 有权
标题翻译：减少伴侣动物腹泻的方法
公开(公告)号：US08685943B2
公开(公告)日：2014-04-01
申请号：US10942397
申请日：2004-09-16
申请人： Wai Cheuk , Chistina Khoo
发明人： Wai Cheuk , Chistina Khoo
IPC分类号： A61K31/00 , A61K31/715
CPC分类号： A61K31/715 , A23K20/163 , A23K50/40 , A61K31/716 , A61K31/717 , A61K31/719 , A61K31/721 , A61K31/723 , A61K31/734 , A61K31/736 , A61K45/06 , A61K47/36 , H04L25/03834 , H04L27/2017
摘要： Compositions (including pharmaceutical compositions, foods, supplements, toys and treats) comprising a microbial exopolysaccharide are provided as well as methods for preventing or reducing diarrhea in a mammal wherein the method comprises administering a therapeutically amount of a microbial exopolysaccharide to a mammal in need thereof.
摘要翻译：提供了包含微生物外多糖的组合物（包括药物组合物，食品，补充剂，玩具和治疗剂）以及用于预防或减少哺乳动物腹泻的方法，其中所述方法包括向有需要的哺乳动物施用治疗量的微生物外多糖。

13. 发明申请

US20050042260A1 Method and composition 有权
标题翻译：用于预防或治疗腹泻的方法和组合物
公开(公告)号：US20050042260A1
公开(公告)日：2005-02-24
申请号：US10942397
申请日：2004-09-16
申请人： Wai Cheuk , Christina Khoo
发明人： Wai Cheuk , Christina Khoo
IPC分类号： H04L25/03 , H04L27/20 , A61K31/715 , A23K1/165
CPC分类号： A61K31/715 , A23K20/163 , A23K50/40 , A61K31/716 , A61K31/717 , A61K31/719 , A61K31/721 , A61K31/723 , A61K31/734 , A61K31/736 , A61K45/06 , A61K47/36 , H04L25/03834 , H04L27/2017
摘要： Compositions (including pharmaceutical compositions, foods, supplements, toys and treats) comprising a microbial exopolysaccharide are provided as well as methods for preventing or reducing diarrhea in a mammal wherein the method comprises administering a therapeutically amount of a microbial exopolysaccharide to a mammal in need thereof.
摘要翻译：提供了包含微生物外多糖的组合物（包括药物组合物，食品，补充剂，玩具和治疗剂）以及用于预防或减少哺乳动物腹泻的方法，其中所述方法包括向有需要的哺乳动物施用治疗量的微生物外多糖。

14. 发明申请

US20180256615A1 COMPOSITION FOR MAINTAINING LACTOBACILLUS DOMINANCE 审中-公开
公开(公告)号：US20180256615A1
公开(公告)日：2018-09-13
申请号：US15758548
申请日：2015-09-29
申请人： KIMBERLY-CLARK WORLDWIDE, INC.
发明人： Jingru LI , Lindsay Adrienne PEED , Cheryce Francina JOYNER , Rebecca Ann VONGSA , David William KOENIG , Ryan Daniel BARTELL
IPC分类号： A61K31/702 , A61K31/7004 , A61K31/7016 , A61K31/719 , A61K47/12 , A61K9/00
CPC分类号： A61K31/702 , A61K9/0034 , A61K31/19 , A61K31/191 , A61K31/192 , A61K31/194 , A61K31/7004 , A61K31/7016 , A61K31/719 , A61K47/12 , A61P15/02 , Y02A50/473 , A61K2300/00
摘要： The present invention provides compositions and formulations capable of maintaining or promoting the growth of certain strains of Lactobacilli spp. The compositions and formulations generally comprise only a single therapeutic agent selected from the group consisting of isomaltulose, maltitol, pullulan, maltotriose, 2-deoxy-D-ribose, 1-kestose and erlose. The single therapeutic agent is the sole source of carbon for bacterium when administered to a user. Despite comprising only a single therapeutic agent the compositions have been shown to promote the growth and maintenance of beneficial lactobacilli and to effectively inhibit the growth of pathogens associated with urogenital infections. As such administration of the compositions maintain a healthy microflora balance in the urogenital area.

15. 发明申请

US20170189444A1 POLYMERIC COMPOSITIONS AND RELATED SYSTEMS AND METHODS FOR REGULATING BIOLOGICAL HYDROGELS 审中-公开
公开(公告)号：US20170189444A1
公开(公告)日：2017-07-06
申请号：US15399711
申请日：2017-01-05
申请人： CALIFORNIA INSTITUTE OF TECHNOLOGY
发明人： Rustem F. ISMAGILOV , Sujit S. DATTA , Asher Preska STEINBERG , Said R. BOGATYREV
IPC分类号： A61K31/765
CPC分类号： A61K31/765 , A61K9/0031 , A61K9/0036 , A61K31/716 , A61K31/719 , A61K31/732 , A61K31/77 , A61K35/747 , A61K45/06 , A61K2300/00
摘要： Polymeric composition and related methods and systems for regulating the structure of hydrogels are described. In particular, by varying the physiochemical properties of the polymeric composition, the structure of the hydrogels can be reversibly compressed or decompressed.

16. 发明申请

US20140171386A1 Method and Composition to Reduce Diarrhea in a Companion Animal 审中-公开
标题翻译：减少伴侣动物腹泻的方法和组成
公开(公告)号：US20140171386A1
公开(公告)日：2014-06-19
申请号：US14188054
申请日：2014-02-24
申请人： Hill's Pet Nutrition, Inc.
发明人： Wai Lun Cheuk , Christina Khoo
IPC分类号： A61K31/715
CPC分类号： A61K31/715 , A23K20/163 , A23K50/40 , A61K31/716 , A61K31/717 , A61K31/719 , A61K31/721 , A61K31/723 , A61K31/734 , A61K31/736 , A61K45/06 , A61K47/36 , H04L25/03834 , H04L27/2017
摘要： Compositions (including pharmaceutical compositions, foods, supplements, toys and treats) comprising a microbial exopolysaccharide are provided as well as methods for preventing or reducing diarrhea in a mammal wherein the method comprises administering a therapeutically amount of a microbial exopolysaccharide to a mammal in need thereof.
摘要翻译：提供了包含微生物外多糖的组合物（包括药物组合物，食品，补充剂，玩具和治疗剂）以及用于预防或减少哺乳动物腹泻的方法，其中所述方法包括向有需要的哺乳动物施用治疗量的微生物外多糖。

17. 发明申请

US20090274636A1 TOOTH ENAMEL DISSOLUTION INHIBITOR 审中-公开
标题翻译：牙科ENAMEL溶解抑制剂
公开(公告)号：US20090274636A1
公开(公告)日：2009-11-05
申请号：US12306644
申请日：2007-06-27
申请人： Shigeo Shinohara , Sachiyo Igarashi
发明人： Shigeo Shinohara , Sachiyo Igarashi
IPC分类号： A61K8/73 , A61P1/02
CPC分类号： A61K31/736 , A61K8/73 , A61K8/735 , A61K8/737 , A61K31/719 , A61K31/723 , A61K31/724 , A61K31/731 , A61K31/732 , A61Q11/00
摘要： An object of the present invention is to provide a tooth enamel dissolution (decalcification) inhibitor that can inhibit the dissolution of tooth enamel to keep teeth healthy.The tooth enamel dissolution inhibitor contains at least one member selected from the group consisting of guar gum, glucomannan, β-cyclodextrin, tragacanth gum, carrageenan, locust bean gum, hyaluronic acid, pullulan, pectin, and xanthan gum.
摘要翻译：本发明的目的是提供一种能够抑制牙釉质溶解以保持牙齿健康的牙釉质溶解（脱钙）抑制剂。牙釉质溶解抑制剂含有选自瓜尔胶，葡甘聚糖，β-环糊精，黄蓍胶，角叉菜胶，刺槐豆胶，透明质酸，支链淀粉，果胶和黄原胶中的至少一种。

18. 发明申请

US20080160164A1 Method and Composition 失效
标题翻译：用于预防或治疗腹泻的方法和组合物
公开(公告)号：US20080160164A1
公开(公告)日：2008-07-03
申请号：US12049546
申请日：2008-03-17
申请人： Wai Cheuk , Christina Khoo
发明人： Wai Cheuk , Christina Khoo
IPC分类号： A23K1/16
CPC分类号： A61K31/715 , A23K20/163 , A23K50/40 , A61K31/716 , A61K31/717 , A61K31/719 , A61K31/721 , A61K31/723 , A61K31/734 , A61K31/736 , A61K45/06 , A61K47/36 , H04L25/03834 , H04L27/2017
摘要： Compositions (including pharmaceutical compositions, foods, supplements, toys and treats) comprising a microbial exopolysaccharide are provided as well as methods for preventing or reducing diarrhea in a mammal wherein the method comprises administering a therapeutically amount of a microbial exopolysaccharide to a mammal in need thereof.
摘要翻译：提供了包含微生物外多糖的组合物（包括药物组合物，食品，补充剂，玩具和治疗剂）以及用于预防或减少哺乳动物腹泻的方法，其中所述方法包括向有需要的哺乳动物施用治疗量的微生物外多糖。

19. 发明授权

US07297687B2 Method of treating infectious diseases with polysaccharide derivatives 失效
标题翻译：用多糖衍生物治疗感染性疾病的方法
公开(公告)号：US07297687B2
公开(公告)日：2007-11-20
申请号：US10500807
申请日：2003-01-10
申请人： Vera Haack , Thomas Heinze , Michaela Schmidtke , Ute Möllmann , Hans-Martin Dahse , Albert Härtl
发明人： Vera Haack , Thomas Heinze , Michaela Schmidtke , Ute Möllmann , Hans-Martin Dahse , Albert Härtl
IPC分类号： A61K31/718 , A61K31/715 , C08B31/00
CPC分类号： A61K31/717 , A61K31/715 , A61K31/716 , A61K31/718 , A61K31/719 , A61K31/721
摘要： The present invention relates to a method of treating infectious diseases, that involves: (a) providing an alpha-glycosidically linked starch polysaccharide derivative; and (b) inhibiting the growth of an infectious disease by administering a composition comprising the alpha-glycosidically linked starch polysaccharide derivative. The alpha-glycosidically linked starch polysaccharide derivative represented by the following general formula I, in which: the alpha-glycosidically linked starch polysaccharide derivative has a degree of quaternary ammonium group substitution of from 0.4 to 2.0; n is 2-4; R1 is selected from the group consisting of C1-4 alkyl, benzyl and benzyl substituted with a member selected from the group consisting of C1-3 alkyl, halogen, alcoxy, carbamoyl, alkoxycarbonyl, cyano, dialkylamino and hydrogen; R2 and R3 are each independently selected from the group consisting of C1-4 alkyl, benzyl and benzyl substituted with a member selected from the group consisting of C1-3 alkyl, halogen, alcoxy, carbamoyl, alkoxycarbonyl, cyano and dialkylamino; and X is an anion selected from the group consisting of halide, hydroxide, sulfate, hydrogen sulfate and carboxylate.
摘要翻译：本发明涉及一种治疗感染性疾病的方法，其涉及：（a）提供α-糖苷连接的淀粉多糖衍生物; 和（b）通过施用包含α-糖苷连接的淀粉多糖衍生物的组合物来抑制感染性疾病的生长。由以下通式I表示的α-糖苷连接的淀粉多糖衍生物，其中：α-糖苷连接的淀粉多糖衍生物的季铵基取代度为0.4〜2.0; n为2-4; R 1选自C 1-4烷基，苄基和被选自C 1-3烷基的成员取代的苄基，烷基，卤素，烷氧基，氨基甲酰基，烷氧基羰基，氰基，二烷基氨基和氢; R 2和R 3各自独立地选自C 1-4烷基，苄基和被选自以下的成员取代的苄基：由C 1-3烷基，卤素，烷氧基，氨基甲酰基，烷氧基羰基，氰基和二烷基氨基组成的组; X是选自卤化物，氢氧化物，硫酸盐，硫酸氢盐和羧酸盐的阴离子。

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