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11. 发明授权

US09610380B2 Vertebral body augmentation systems comprising microbubbles 有权
公开(公告)号：US09610380B2
公开(公告)日：2017-04-04
申请号：US14316135
申请日：2014-06-26
申请人： DePuy Synthes Products, Inc.
发明人： Thomas M DiMauro
IPC分类号： A61F2/46 , A61L24/06 , A61L24/00 , A61M25/10 , A61L29/14
CPC分类号： A61F2/46 , A61B17/8816 , A61B17/8855 , A61B90/39 , A61B2090/3929 , A61F2/4601 , A61L24/001 , A61L24/06 , A61L29/14 , A61L2400/06 , A61L2430/02 , A61L2430/38 , A61M25/1002 , A61M25/1006 , A61M2025/1061 , A61M2210/02 , C08L33/12
摘要： Adding gas-filled microbubbles to both the saline solution of either a kyphoplasty balloon or a vertebroplasty cement allows the clinician to assess via ultrasound both the location and expansion of the balloon and the location of the cement during vertebral body augmentation procedures without the use of fluoroscopy.

12. 发明申请

US20170069073A1 SYSTEM AND METHOD DETECTING AND ADJUSTING FOR REFERENCE MARKER ERRORS IN SURGICAL NAVIGATION SYSTEMS 审中-公开
标题翻译：系统和方法检测和调整外科导航系统中的参考标记错误
公开(公告)号：US20170069073A1
公开(公告)日：2017-03-09
申请号：US15125245
申请日：2014-09-15
申请人： Gal SELA , Arun Victor JAGGA
发明人： Gal SELA , Arun Victor JAGGA
IPC分类号： G06T7/00 , A61B90/00 , A61B34/20
CPC分类号： A61B90/39 , A61B34/10 , A61B34/20 , A61B90/50 , A61B2034/104 , A61B2034/107 , A61B2034/2048 , A61B2034/2051 , A61B2034/2055 , A61B2090/364 , A61B2090/373 , A61B2090/3929 , A61B2090/3937 , A61B2090/3983 , G06T7/248 , G06T7/33 , G06T7/337 , G06T7/74 , G06T2207/10021 , G06T2207/10048 , G06T2207/10076 , G06T2207/10081 , G06T2207/10088 , G06T2207/10104 , G06T2207/10136 , G06T2207/30016 , G06T2207/30096 , G06T2207/30101 , G06T2207/30204
摘要： Systems, and methods are provided for computer based method for determining a source of a registration error in a surgical navigation system, by registering at least two patient reference markers in a common coordinate space, positioning at least one reference marker in a known position with respect to at least one of two patient reference markers. A relative position of the at least two patient reference markers with respect to each other in the common coordinate space is monitored, as well as a position of said at least one reference marker with respect to a first of the at least two patient reference markers. Upon detecting a change in relative position of the least at least two patient reference markers with respect to each other, determining if the position of said at least one reference marker with respect to the first of the at least two patient reference markers has changed, and if yes, designating that the first patient reference marker has moved, and if not, designating that the second of the at least two patient reference markers has moved.
摘要翻译：提供了用于基于计算机的方法的系统和方法，用于通过在公共坐标空间中登记至少两个患者参考标记来确定手术导航系统中的登记误差的来源，将至少一个参考标记定位在已知位置上至两个患者参考标记中的至少一个。监测在公共坐标空间中相对于彼此的至少两个患者参考标记的相对位置以及所述至少一个参考标记相对于至少两个患者参考标记中的第一个的位置。在检测到所述至少两个患者参考标记相对于彼此的相对位置的变化时，确定所述至少一个参考标记相对于所述至少两个患者参考标记中的第一个的位置是否已改变，以及如果是，则指定第一患者参考标记已经移动，如果不是则指定至少两个患者参考标记中的第二个已经移动。

13. 发明申请

US20170027605A1 SIGNAL VERSUS NOISE DISCRIMINATION NEEDLE WITH PIEZOELECTRIC POLYMER SENSORS 审中-公开
标题翻译：带压电聚合物传感器的信号噪声识别针
公开(公告)号：US20170027605A1
公开(公告)日：2017-02-02
申请号：US15302176
申请日：2015-04-02
申请人： KONINKLIJKE PHILIPS N.V.
发明人： RAMON QUIDO ERKAMP , AMEET KUMAR JAIN , FRANCOIS GUY GERARD MARIE VIGNON , SHYAM BHARAT
IPC分类号： A61B17/34 , A61B8/08
CPC分类号： A61B17/3403 , A61B8/0841 , A61B8/4494 , A61B8/5269 , A61B17/3417 , A61B2017/3413 , A61B2018/00529 , A61B2018/1425 , A61B2090/3925 , A61B2090/3929 , A61M25/0108
摘要： A medical device includes a device body (14), a first sensor (10) formed on the device body and including a piezoelectric polymer as a sensor element, the piezoelectric polymer configured to receive ultrasonic energy and a first electrical trace (24) connecting to the first sensor and extending along the device body. A dummy sensor (11) is formed on the device body in proximity of the first sensor and includes a dummy sensor element. A second electrical trace (25) connects to the dummy sensor and extends along the device body in a configuration relative to the first electrical trace, wherein a signal event is discriminated between a signal and noise using a response measured on one or more of the first sensor, the dummy sensor or the second electrical trace.
摘要翻译：医疗装置包括装置主体（14），形成在装置主体上的第一传感器（10），其包括作为传感器元件的压电聚合物，所述压电聚合物构造成接收超声能量和第一电迹线（24），其连接到第一传感器并沿设备主体延伸。在第一传感器附近的器件主体上形成虚拟传感器（11），并且包括虚拟传感器元件。第二电迹线（25）连接到虚拟传感器并且以相对于第一电迹线的配置沿着器件本体延伸，其中使用在第一和第二电极上的一个或多个上测量的响应来在信号和噪声之间区分信号事件传感器，虚拟传感器或第二电迹线。

14. 发明申请

US20160310760A1 REAL-TIME FUSION OF ANATOMICAL ULTRASOUND INFORMATION AND RADIATION DELIVERY INFORMATION FOR RADIATION THERAPIES 审中-公开
标题翻译：解剖学信息的实时融合和辐射治疗的辐射传递信息
公开(公告)号：US20160310760A1
公开(公告)日：2016-10-27
申请号：US15102333
申请日：2014-12-05
申请人： KONINKLIJKE PHILIPS N.V
发明人： SHYAM BHARAT , EHSAN DEHGHAN MARVAST , AMEET KUMAR JAIN , AMIR MOHAMMAD TAHMASEBI MARAGHOOSH , FRANCOIS GUY GERARD MARIE VIGNON
IPC分类号： A61N5/10 , A61B8/08 , A61B6/03 , A61B8/00
CPC分类号： A61N5/1039 , A61B6/032 , A61B8/0833 , A61B8/4483 , A61B8/483 , A61B2090/3929 , A61N5/1038 , A61N5/1067 , A61N2005/1051 , A61N2005/1058 , A61N2005/1061
摘要： A radiation therapy delivery system (10) includes an ultrasound imaging unit (26), a radiation therapy delivery mechanism (12, 56, 70, 88), a plurality of fiducials (22, 90) located internal to the subject, an image fusion unit (40), and a delivery evaluation unit (38). The ultrasound imaging unit (26) includes a transducer (30) that emits ultrasonic sound waves to image in real-time an anatomic portion of a subject (16) in a first coordinate system. The radiation therapy delivery mechanism (12, 56, 70, 88) delivers amounts of therapeutic radiation in the anatomic portion of the subject in a second coordinate system. The fiducials (22, 90) include implants or a trans-rectal ultrasound probe (80). The image fusion unit (40) registers locations of the plurality of fiducials to at least one of the first and the second coordinate system and tracks the locations of the fiducials in real-time. The delivery evaluation unit (38) identifies locations and the amounts of delivered therapeutic radiation relative to the imaged real-time anatomic portion of the subject.
摘要翻译：放射治疗递送系统（10）包括超声成像单元（26），放射线治疗递送机构（12,56,70,88），位于对象内部的多个基准点（22,90），图像融合单元（40）和传送评估单元（38）。超声波成像单元（26）包括发射超声波以实时成像第一坐标系中的被摄体（16）的解剖部分的换能器（30）。辐射治疗递送机构（12,56,70,88）在第二坐标系统中在受试者的解剖部分中传送治疗辐射量。基准（22,90）包括植入物或经直肠超声探头（80）。图像融合单元（40）将多个基准的位置记录到第一和第二坐标系中的至少一个，并且实时地跟踪基准的位置。递送评估单元（38）识别相对于被摄体的被成像的实时解剖部分递送的治疗辐射的位置和量。

15. 发明授权

US09261596B2 Method for monitoring of medical treatment using pulse-echo ultrasound 有权
标题翻译：使用脉冲回波超声检查治疗方法
公开(公告)号：US09261596B2
公开(公告)日：2016-02-16
申请号：US12915358
申请日：2010-10-29
申请人： T. Douglas Mast , Waseem Faidi , Inder Raj S. Makin , Peter G. Barthe , Michael H. Slayton
发明人： T. Douglas Mast , Waseem Faidi , Inder Raj S. Makin , Peter G. Barthe , Michael H. Slayton
IPC分类号： A61B8/00 , G01S15/89 , A61B8/08 , A61B8/12 , A61B17/32 , A61N7/02 , A61B10/02 , A61B17/22 , A61B17/29 , A61B19/00 , A61N7/00
CPC分类号： A61B8/08 , A61B8/12 , A61B8/14 , A61B8/4488 , A61B8/5207 , A61B8/5238 , A61B8/5276 , A61B10/0233 , A61B17/22012 , A61B17/2202 , A61B17/29 , A61B17/320092 , A61B2090/378 , A61B2090/3784 , A61B2090/3929 , A61B2090/3975 , A61N7/022 , A61N2007/0078 , G01S15/899
摘要： A method for ultrasound imaging of anatomical tissue. A first signal is received from a first imaging ultrasound wave which has been reflected from a location in the anatomical tissue during a first time period. A second signal is received from a second imaging ultrasound wave which has been reflected from the location in the anatomical tissue during a later second time period, following a discrete medical treatment. The second signal is subtracted from the first signal to form a difference signal. The difference signal may be scaled, spatially filtered, then used to generate an indication, the indication showing the effect of the medical treatment in the location in the anatomical tissue.
摘要翻译：解剖组织超声成像的方法。从第一时间段内从解剖组织中的位置反射的第一成像超声波接收第一信号。在离散的医疗处理之后，在稍后的第二时间段内已经从解剖组织中的位置反射的第二成像超声波接收第二信号。从第一信号中减去第二信号以形成差分信号。差分信号可以被缩放，空间过滤，然后用于产生指示，该指示表示在解剖组织中的位置处的医疗的影响。

16. 发明申请

US20150374879A1 Vertebral Body Augmentation Systems Comprising Microbubbles 有权
标题翻译：包括微泡的椎体增强系统
公开(公告)号：US20150374879A1
公开(公告)日：2015-12-31
申请号：US14316135
申请日：2014-06-26
申请人： DEPUY SYNTHES PRODUCTS, LLC
发明人： Thomas M DiMauro
IPC分类号： A61L24/06 , A61L24/00 , A61M25/10
CPC分类号： A61F2/46 , A61B17/8816 , A61B17/8855 , A61B90/39 , A61B2090/3929 , A61F2/4601 , A61L24/001 , A61L24/06 , A61L29/14 , A61L2400/06 , A61L2430/02 , A61L2430/38 , A61M25/1002 , A61M25/1006 , A61M2025/1061 , A61M2210/02 , C08L33/12
摘要： Adding gas-filled microbubbles to both the saline solution of either a kyphoplasty balloon or a vertebroplasty cement allows the clinician to assess via ultrasound both the location and expansion of the balloon and the location of the cement during vertebral body augmentation procedures without the use of fluoroscopy.
摘要翻译：将气体填充的微泡加入到椎体后凸成形术球囊或椎体成形术水泥的盐水溶液中允许临床医生通过超声波来评估球囊的位置和扩张以及在椎体增大过程中水泥的位置，而不使用荧光透视。

17. 发明申请

US20150282892A1 Simulated Bone or Tissue Manipulation 审中-公开
标题翻译：模拟骨或组织手术
公开(公告)号：US20150282892A1
公开(公告)日：2015-10-08
申请号：US14743895
申请日：2015-06-18
申请人： DePuy Synthes Products, Inc.
发明人： Robert FRIGG , Stuart WEIKEL , Stefan SCHWER , Geoffrey FLEXNER , Ross Jonathan HAMEL
IPC分类号： A61B19/00
CPC分类号： G01R33/285 , A61B5/055 , A61B5/4836 , A61B5/7405 , A61B6/032 , A61B6/52 , A61B8/0841 , A61B8/52 , A61B17/88 , A61B34/10 , A61B34/20 , A61B90/36 , A61B90/39 , A61B2034/2063 , A61B2090/374 , A61B2090/3762 , A61B2090/3912 , A61B2090/3929 , A61B2090/3958 , A61B2090/3966 , A61B2090/3983 , A61B2090/3987 , A61C19/04 , G01R33/5608 , G06F19/00 , G16H50/50
摘要： The present invention is directed to a system and method for performing tissue, preferably bone tissue manipulation. The system and method may include implanting markers on opposite sides of a bone, fractured bone or tissue to facilitate bone or tissue manipulation, preferably in-situ closed fracture reduction. The markers are preferably configured to be detected by one or more devices, such as, for example, a detection device so that the detection device can determine the relative relationship of the markers. The markers may also be capable of transmitting and receiving signals. An image may be captured of the bone or tissue and the attached markers. From the captured image, the orientation of each marker relative to the bone fragment may be determined. Next, the captured image may be manipulated in a virtual or simulated environment until a desired restored orientation has been achieved. The orientation of the markers in the desired restored orientation may then be determined. The desired relationship between markers may then be programmed into, for example, the detection device. Next, actual physical reduction and/or manipulation of the bone may begin. During the manipulation procedure, the orientation of the markers may be continuously monitored and when the markers substantially align with the virtual or simulated orientation of the markers in the desired restored orientation, an indicator signal is transmitted.
摘要翻译：本发明涉及用于进行组织，优选骨组织操作的系统和方法。该系统和方法可以包括在骨，骨折骨或组织的相对侧上植入标记物以便于骨或组织操作，优选原位闭合骨折的减少。标记优选地被配置为由一个或多个装置（例如检测装置）检测，使得检测装置可以确定标记的相对关系。标记还可能能够发送和接收信号。可以捕获骨骼或组织以及附着标记物的图像。从捕获的图像可以确定每个标记物相对于骨片段的取向。接下来，可以在虚拟或模拟环境中操纵拍摄的图像，直到达到期望的恢复取向。然后可以确定所需恢复取向中的标记的取向。然后可以将标记之间的期望关系编程到例如检测装置中。接下来，可以开始骨的实际物理减少和/或操纵。在操作过程中，可以连续地监视标记的取向，并且当标记基本上与标记的虚拟或模拟定向在所需的恢复方向对准时，发送指示符信号。

18. 发明授权

US09066681B2 Methods and systems for enhancing ultrasonic visibility of energy-delivery devices within tissue 有权
标题翻译：提高组织内能量输送装置超声能见度的方法和系统
公开(公告)号：US09066681B2
公开(公告)日：2015-06-30
申请号：US13836353
申请日：2013-03-15
申请人： Covidien LP
发明人： Gene H. Arts , Darion R. Peterson , Joseph D. Brannan , John R. Vantuno , Eric W. Larson
IPC分类号： A61B18/04 , A61B8/08 , A61B18/14 , A61B18/18 , A61B18/00 , A61B19/00 , A61B17/34 , A61B17/00
CPC分类号： A61B18/1815 , A61B8/0841 , A61B8/481 , A61B18/1477 , A61B18/1482 , A61B18/1492 , A61B2017/00084 , A61B2017/00398 , A61B2017/00539 , A61B2017/3413 , A61B2018/00023 , A61B2018/00577 , A61B2018/00642 , A61B2018/00994 , A61B2018/1861 , A61B2018/1869 , A61B2090/378 , A61B2090/3929 , A61B2217/007 , A61B2562/0219
摘要： In accordance with aspects of the present disclosure, electrosurgical systems are provided generally including at least one energy-delivery device for delivering energy to tissue when inserted or embedded within tissue. The energy-delivery device can be a tissue ablation device, such as an ablation probe, needle, etc. for ablating tissue as commonly known in the art. The electrosurgical systems include at least one structure and/or operational characteristic for enhancing ultrasonic visibility of the energy-delivery devices within tissue during ultrasonography.
摘要翻译：根据本公开的方面，通常提供电外科系统，其包括至少一个能量输送装置，用于在插入或嵌入组织内时将能量递送至组织。能量输送装置可以是组织消融装置，例如用于烧蚀组织的消融探针，针等，这是本领域公知的。电外科系统包括至少一个结构和/或操作特征，用于在超声检查期间增强组织内的能量输送装置的超声波可见性。

19. 发明授权

US09005144B2 Tissue-retaining systems for ultrasound medical treatment 有权
标题翻译：用于超声医疗的组织保持系统
公开(公告)号：US09005144B2
公开(公告)日：2015-04-14
申请号：US13719172
申请日：2012-12-18
申请人： Michael H. Slayton , Inder Raj Makin , Robert Dunki-Jacobs , Richard C. Pellegrino
发明人： Michael H. Slayton , Inder Raj Makin , Robert Dunki-Jacobs , Richard C. Pellegrino
IPC分类号： A61N7/00 , A61B8/12 , A61B8/00 , A61B17/32 , A61N7/02 , A61B10/02 , A61B17/22 , A61B17/29 , A61B19/00
CPC分类号： A61N7/00 , A61B8/12 , A61B8/445 , A61B8/4488 , A61B10/0233 , A61B17/22012 , A61B17/2202 , A61B17/29 , A61B17/320092 , A61B2090/378 , A61B2090/3784 , A61B2090/3929 , A61B2090/3975 , A61N7/022 , A61N2007/0078
摘要： An ultrasound medical treatment system includes an end effector insertable into a patient. The end effector includes a tissue-retaining device. The tissue-retaining device includes a first tissue-retaining member having an ultrasound medical-treatment transducer and includes a second tissue-retaining member. The first and second tissue-retaining members are operatively connected together to retain patient tissue between the first and second tissue-retaining members and to release patient tissue so retained. In one example, the second tissue-retaining member has an ultrasound reflector. In the same or a different example, the ultrasound medical-treatment transducer is an ultrasound imaging and medical-treatment transducer.
摘要翻译：超声医疗系统包括可插入病人的末端执行器。末端执行器包括组织保持装置。组织保持装置包括具有超声波医疗换能器的第一组织保持构件，并且包括第二组织保持构件。第一和第二组织保持构件可操作地连接在一起以将患者组织保持在第一和第二组织保持构件之间并且释放如此保留的患者组织。在一个示例中，第二组织保持构件具有超声波反射器。在相同或不同的示例中，超声医疗换能器是超声成像和医疗换能器。

20. 发明申请

US20140250674A1 DISTRACTION DEVICES AND METHOD OF ASSEMBLING THE SAME 有权
标题翻译：分离装置及其装配方法
公开(公告)号：US20140250674A1
公开(公告)日：2014-09-11
申请号：US13791430
申请日：2013-03-08
申请人： ELLIPSE TECHNOLOGIES, INC.
发明人： Scott Pool , Arvin Chang
IPC分类号： A61B17/68
CPC分类号： A61B17/68 , A61B17/7008 , A61B17/7016 , A61B17/702 , A61B17/7068 , A61B17/7216 , A61B90/06 , A61B2017/681 , A61B2090/061 , A61B2090/3925 , A61B2090/3929 , Y10T29/49963 , Y10T29/49966
摘要： A method of assembling a system for manipulating the skeletal system includes obtaining a monolithic member having opposing ends, one end including a housing having an axially extending cavity. A distraction rod is obtained that has opposing ends, a first end having an inner threaded cavity. A rotatable, radially poled magnet is rotationally coupled to a lead screw having threads. The threads of the lead screw are engaged with the threaded cavity of the distraction rod. The magnet and at least a portion of the first end of the distraction rod are inserted into the axially extending cavity such that the distraction rod and the monolithic member are in coaxial relation to one another. The magnet is axially locked in relation to the monolithic member, wherein the axially locked magnet is capable of rotation. The distraction rod is rotationally locked in relation to the monolithic member.
摘要翻译：组装用于操纵骨骼系统的系统的方法包括获得具有相对端部的整体构件，一端包括具有轴向延伸空腔的壳体。获得具有相对端的牵引杆，第一端具有内螺纹腔。可旋转的，径向极化的磁体旋转地联接到具有螺纹的导螺杆。导螺杆的螺纹与牵引杆的螺纹腔接合。磁体和牵引杆的第一端的至少一部分被插入到轴向延伸的空腔中，使得牵引杆和整体构件彼此同轴。磁体相对于整体构件轴向锁定，其中轴向锁定的磁体能够旋转。牵引杆相对于整体构件旋转锁定。

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