专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明授权

US07321831B2 Nucleic acid fragment-fixed electrode and its use 有权
标题翻译：核酸片段固定电极及其用途
公开(公告)号：US07321831B2
公开(公告)日：2008-01-22
申请号：US10231242
申请日：2002-08-30
申请人： Yoshihiko Makino , Yoshihiko Abe
发明人： Yoshihiko Makino , Yoshihiko Abe
IPC分类号： G01N33/48 , C12Q1/00 , C12Q1/68 , G01N33/00 , G06F19/00
CPC分类号： C07H21/00 , B82Y15/00 , B82Y30/00
摘要： It is an object of the present invention to provide a nucleic acid fragment-fixed electrode wherein a probe nucleic acid fragment is fixed on the electrode stably and in an amount-controlled manner. The present invention provides a nucleic acid fragment-fixed electrode wherein a nucleic acid fragment is fixed on the surface of a multi-component self-assembled monolayer of two or more different components which is formed on the electrode, by a covalent bond via a bifunctional linking molecule.
摘要翻译：本发明的目的是提供一种核酸片段固定电极，其中探针核酸片段稳定地并以量控制的方式固定在电极上。本发明提供了一种核酸片段固定电极，其中核酸片段固定在多组分自组装单层的两个或多个不同组分的表面上，该组分形成在电极上，通过共价键通过双功能连接分子。

12. 发明授权

US07132266B2 Method and kit for analyzing target nucleic acid fragment 有权
公开(公告)号：US07132266B2
公开(公告)日：2006-11-07
申请号：US10292725
申请日：2002-11-12
申请人： Yoshihiko Makino , Yoshihiko Abe
发明人： Yoshihiko Makino , Yoshihiko Abe
IPC分类号： C12P19/34 , C12Q1/68 , C07H21/00 , C07H21/02 , C07H21/04
CPC分类号： C12Q1/6825
摘要： A method of analyzing a target nucleic acid fragment is provided that is capable of being performed simply and promptly, by anyone, using a compact device without requirement of specific technique or complex operation. The method comprises timely detection of a double-stranded nucleic acid fragment formed during the polymerase extension reaction due to a specific base sequence of the target nucleic acid fragment as increase of an electrochemical response under the existence of an electrochemically active intercalator; and the kit utilizes the method.

13. 发明授权

US06864055B2 Method for detecting nucleic acids 有权
标题翻译：检测核酸的方法
公开(公告)号：US06864055B2
公开(公告)日：2005-03-08
申请号：US09887625
申请日：2001-06-22
申请人： Yoshihiko Makino , Yoshihiko Abe , Masashi Ogawa , Makoto Takagi , Shigeori Takenaka , Kenichi Yamashita
发明人： Yoshihiko Makino , Yoshihiko Abe , Masashi Ogawa , Makoto Takagi , Shigeori Takenaka , Kenichi Yamashita
IPC分类号： G01N33/53 , C07B61/00 , C07K14/00 , C12M1/00 , C12N15/09 , C12Q1/68 , G01N27/416 , G01N33/566 , B01D57/02 , C12P19/34 , G01N30/02
CPC分类号： C12Q1/6825 , C07K14/003 , C12Q1/6837 , C40B40/00 , C12Q2565/501 , C12Q2565/102 , C12Q2565/607
摘要： A method of detecting nucleic acid fragments in plural samples is performed by the steps of: attaching an electroconductive label to nucleic acid fragments in one sample and attaching a different electroconductive label to nucleic acid fragments in another sample; preparing a mixture of these samples; spotting the mixture on an electroconductive microarray having plural electrodes onto which probe molecules complementary to the nucleic acid fragments are fixed, so that hybridization between the nucleic acid fragments and the probe molecules on the electroconductive microarray can proceed to form hybrid structures; applying to the electrode an electric potential corresponding to the oxidation-reduction potential of the former label and detecting on the electrode an electric current; applying to the electrode an electric potential corresponding to the oxidation-reduction potential of the latter label and detecting on the electrode an electric current; and comparing the electric current detected in the former detecting procedure and that detected in the latter detecting procedure.
摘要翻译：通过以下步骤进行检测多个样品中的核酸片段的方法：将导电标记物附着在一个样品中的核酸片段上，并将不同的导电标记连接到另一个样品中的核酸片段; 准备这些样品的混合物; 在具有多个电极的导电微阵列上将该混合物点样，在该导电微阵列上固定有与核酸片段互补的探针分子，使得导电微阵列上的核酸片段和探针分子之间的杂交可以进行以形成杂化结构; 向所述电极施加与所述前标签的氧化还原电位相对应的电位，并在所述电极上检测电流; 向所述电极施加与后一标签的氧化还原电位相对应的电位，并在所述电极上检测电流; 并比较前一检测程序检测的电流和后一检测程序中检测的电流。

14. 发明授权

US06713255B1 DNA chip, PNA chip, and their preparation methods 有权
标题翻译： DNA芯片，PNA芯片及其制备方法
公开(公告)号：US06713255B1
公开(公告)日：2004-03-30
申请号：US09589221
申请日：2000-06-07
申请人： Yoshihiko Makino , Yoshihiko Abe , Makoto Takagi , Shigeori Takenaka , Kenichi Yamashita , Masashi Ogawa
发明人： Yoshihiko Makino , Yoshihiko Abe , Makoto Takagi , Shigeori Takenaka , Kenichi Yamashita , Masashi Ogawa
IPC分类号： C12Q168
CPC分类号： C07K14/003 , B01J19/0046 , B01J2219/00529 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/00637 , B01J2219/00641 , B01J2219/00659 , B01J2219/00722 , B01J2219/00729 , C07B2200/11 , C07H21/00 , C12Q1/6837 , C40B40/06 , C12Q2565/607
摘要： A DNA chip (or PNA chip) composed of a solid carrier and plural DNA fragments (or PNA fragments) fixed onto is the solid carrier at each one end, wherein a plurality of short chain spacer molecules having a hydrophilic moiety at each one end are fixed at each another end onto a surface of the solid carrier having no DNA fragments (or no PNA fragments) on its surface is effective for high sensitive quantitative analysis of a nucleic acid fragment complementary to the DNA fragment (or PNA fragment).
摘要翻译：由固体载体和固定在其上的多个DNA片段（或PNA片段）组成的DNA芯片（或PNA芯片）是每一端的固体载体，其中在每一端具有亲水部分的多个短链间隔基分子是固定在其表面上没有DNA片段（或没有PNA片段）的固体载体的表面上对于与DNA片段（或PNA片段）互补的核酸片段的高敏感性定量分析是有效的。

15. 发明授权

US07737214B2 Adhesion preventive material 有权
标题翻译：防粘连材料
公开(公告)号：US07737214B2
公开(公告)日：2010-06-15
申请号：US10592956
申请日：2005-03-11
申请人： Yoshihiko Abe , Yutaro Sonoda , Jun Konishi , Takao Anzai , Miyuki Shimizu
发明人： Yoshihiko Abe , Yutaro Sonoda , Jun Konishi , Takao Anzai , Miyuki Shimizu
IPC分类号： C08B31/00 , C08B37/00 , A01N43/04 , A61K31/715
CPC分类号： A61L31/042 , A61K31/715 , C08B31/02 , C08B37/0012 , C08B37/0018 , C08B37/0021
摘要： An adhesion preventive material including a cross-linking polysaccharide derivative containing at least one active ester group introduced in a polysaccharide side chain, which is capable of reacting with an active hydrogen-containing group, and being capable of forming a crosslinked material due to covalent binding among the active ester group and an active hydrogen-containing group upon contact with water under an alkaline condition, is disclosed. The adhesion preventive material is able to reduce preparation works to be carried out while previously estimating the time of application and does not require a special device.
摘要翻译：一种防粘连材料，包括含有至少一种引入多糖侧链的活性酯基的交联多糖衍生物，其能够与含活性氢基团反应，并且能够由于共价结合而形成交联材料在碱性条件下与水接触时，活性酯基和活性含氢基团中。防粘连材料能够在以前估计施用时间的情况下减少要进行的准备工作，并且不需要特殊装置。

16. 发明授权

US07386486B2 Systems and computer readable recording medium for obtaining software via a network for a multifunction image forming apparatus 失效
标题翻译：用于通过多功能图像形成装置的网络获得软件的系统和计算机可读记录介质
公开(公告)号：US07386486B2
公开(公告)日：2008-06-10
申请号：US10900096
申请日：2004-07-28
申请人： Takezo Fujishige , Yoshihiko Abe
发明人： Takezo Fujishige , Yoshihiko Abe
IPC分类号： G06Q30/00 , G06F17/30
CPC分类号： G06Q30/06 , G06F21/572 , G06Q30/0609 , G06Q30/0613 , G06Q30/0633 , G06Q30/0641 , H04N1/00 , H04N1/00962
摘要： A multifunction image forming apparatus accepts voice input of a software name by an order applicant, carries out voice recognizing processing concerning the voice data of the software name that is voice input, and stores the software name recognized by the voice recognizing processing. Then, the multifunction image forming apparatus checks whether the order applicant is a person who has the authority to order the software. In a case where it is determined that the order applicant is a person who has the authority to order, order data including the recognized software name is sent to a software management server via a network. The multifunction image forming apparatus receives data of the software from the software management server, temporarily stores it, and thereafter, reads the data of the stored software, and carries out installing of the software.
摘要翻译：多功能图像形成装置接受订购申请人的软件名称的语音输入，对与语音输入的软件名称的语音数据进行语音识别处理，并存储通过语音识别处理识别的软件名称。然后，多功能图像形成装置检查订购申请者是否具有订购软件的权力的人。在确定订单申请人是具有订购权限的人的情况下，将包括所识别的软件名称的订单数据经由网络发送到软件管理服务器。多功能图像形成装置从软件管理服务器接收软件的数据，暂时存储软件，然后读取存储的软件的数据，并进行软件的安装。

17. 发明申请

US20060095436A1 Networked document partially printing system and method 审中-公开
标题翻译：网络文件部分打印系统和方法
公开(公告)号：US20060095436A1
公开(公告)日：2006-05-04
申请号：US11258893
申请日：2005-10-27
申请人： Yoshihiko Abe
发明人： Yoshihiko Abe
IPC分类号： G06F17/30
CPC分类号： G06F16/95 , G06F2216/17
摘要： A networked printing system includes an electronic document server having a database that stores a plurality of electronic documents of books, which are uniquely identified by a plurality of identification codes, respectively. The electronic document server specifies and allows downloading of a prescribed electronic document matched with an identification code received. A transmitting device is provided to transmit a request for a prescribed electronic document and a corresponding identification code to the electronic document server via a network. A printing device connected to the electronic server document prints a portion of the electronic document in accordance with designation of pages.
摘要翻译：网络打印系统包括具有数据库的电子文档服务器，该数据库分别存储由多个识别代码唯一标识的多本书籍的电子文档。电子文件服务器指定并允许下载与所接收的识别码相匹配的规定的电子文档。提供发送装置，经由网络向电子文档服务器发送规定的电子文档的请求和对应的识别码。连接到电子服务器文档的打印设备根据页面的指定打印电子文档的一部分。

18. 发明授权

US05998158A Glucose free, stable dry analytical element for quantitative analysis of creatine kinase MB isozyme 失效
标题翻译：不含葡萄糖，稳定的干燥分析元素用于定量分析肌酸激酶MB同功酶
公开(公告)号：US05998158A
公开(公告)日：1999-12-07
申请号：US158484
申请日：1998-09-22
申请人： Hideaki Tanaka , Yoshihiko Abe , Kaoru Terashima
发明人： Hideaki Tanaka , Yoshihiko Abe , Kaoru Terashima
IPC分类号： C12Q1/50
CPC分类号： C12Q1/50
摘要： A dry analytical element for quantitatively analyzing creatine kinase MB isozyme is composed of a support and a creatine kinase MB isozyme-detecting agent layer. The detecting layer contains an antibody which specifically inhibits activity of M sub-unit of creatine kinase, creatine phosphate and adenosine diphosphate which react with each other to give adenosine triphosphate in the presence of creatine kinase MB isozyme, a buffer compound which keeps the layer in the range of pH 5.5 to pH 8.5 for the formation of adenosine triphosphate, and an indicator composition which reacts with the formed adenosine triphosphate to give a spectroscopically detectable compound, said indicator composition having hexokinase, nicotinamide-adenine dinucleotide or its phosphate in an oxidized form, and glucose-6-phosphate dehydrogenase but not containing glucose in such amount as to give the spectroscopically detectable compound.
摘要翻译：用于定量分析肌酸激酶MB同功酶的干燥分析元件由载体和肌酸激酶MB同工酶检测剂层组成。检测层含有特异性抑制肌酸激酶，亚磷酸肌酸和磷酸腺苷的M亚单位的活性的抗体，其在肌酸激酶MB同功酶（一种保持该层的缓冲化合物）存在下相互反应，产生三磷酸腺苷用于形成三磷酸腺苷的pH 5.5至pH 8.5的范围，以及与形成的三磷酸腺苷反应以产生光谱可检测化合物的指示剂组合物，所述指示剂组合物具有己糖激酶，烟酰胺 - 腺嘌呤二核苷酸或其氧化形式的磷酸酯和葡萄糖-6-磷酸脱氢酶，但不含葡萄糖，其量使得可得到光谱可检测的化合物。

19. 发明授权

US5928951A Frameless chemical analysis film clip 失效
标题翻译：无框化学分析胶片夹
公开(公告)号：US5928951A
公开(公告)日：1999-07-27
申请号：US883265
申请日：1997-06-26
申请人： Osamu Seshimoto , Yoshihiko Abe , Yasushi Fujisaki
发明人： Osamu Seshimoto , Yoshihiko Abe , Yasushi Fujisaki
IPC分类号： G01N31/22 , G01N33/52 , G01N35/00 , G01N35/10 , G01N21/77
CPC分类号： G01N35/00029 , G01N33/525 , G01N2035/00089 , G01N2035/00108 , Y10T436/11 , Y10T436/112499
摘要： A chemical analysis film chip is prepared by integrally laminating a reagent layer and a spreading layer on a support sheet in this order, or by integrally laminating a water absorbing layer having a hydrophilic polymer as a major component and a porous outermost layer containing therein a reagent on a support sheet in this order, or by superposing a porous layer containing therein a reagent on a support sheet.
摘要翻译：通过依次将支撑片上的试剂层和扩散层整体层叠在一起，或通过将亲水性高分子作为主要成分的吸水层和含有试剂的多孔最外层整体层叠而制备化学分析膜芯片或者通过将含有试剂的多孔层叠置在支撑片上。

20. 发明授权

US08859221B2 Method for measuring high density lipoprotein cholesterol 有权
标题翻译：高密度脂蛋白胆固醇测定方法
公开(公告)号：US08859221B2
公开(公告)日：2014-10-14
申请号：US11798141
申请日：2007-05-10
申请人： Yoshihiko Abe , Nobuhito Masuda , Hiroko Inomata
发明人： Yoshihiko Abe , Nobuhito Masuda , Hiroko Inomata
IPC分类号： C12Q1/60 , G01N33/92
CPC分类号： C12Q1/60 , G01N33/92
摘要： An object to be attained by the present invention is to provide a method for conveniently, rapidly, and specifically measuring HDL-C in a specimen by use of inexpensive materials, and to provide a reagent kit for HDL-C detection and a dry analytical element for HDL-C detection. The present invention provides a method for measuring high density lipoprotein cholesterol (HDL-C) in a body fluid test sample, wherein cholesterol esterase derived from Schizophyllum commune or Pseudomonas sp. and cholesterol oxidase derived from Pseudomonas sp. are used to generate hydrogen peroxide from HDL-C, and thereby HDL-C is selectively measured.
摘要翻译：本发明要达到的目的是提供一种通过使用便宜的材料方便，快速，具体地测量样品中的HDL-C的方法，并提供用于HDL-C检测的试剂盒和干燥分析元件用于HDL-C检测。本发明提供了一种测定体液测试样品中的高密度脂蛋白胆固醇（HDL-C）的方法，其中来源于裂殖酵母（Schizophyllum commune）或假单胞菌属（Pseudomonas sp。）的胆固醇酯酶。和来源于假单胞菌属的胆固醇氧化酶。用于从HDL-C产生过氧化氢，从而选择性地测量HDL-C。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式