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11. 发明申请

US20160070436A1 PLANNING, NAVIGATION AND SIMULATION SYSTEMS AND METHODS FOR MINIMALLY INVASIVE THERAPY 有权
标题翻译：计划，导航和模拟系统以及最小的入侵治疗方法
公开(公告)号：US20160070436A1
公开(公告)日：2016-03-10
申请号：US14769668
申请日：2014-03-14
申请人： Monroe M. THOMAS , Gal SELA , Cameron PIRON , Joshua RICHMOND , Murugathas YUWARAJ , Wes HODGES , Simon ALEXANDER , David GALLOP , William LAU , Sheryl THINGVOLD , Kelly DYER
发明人： Monroe M. Thomas , Gal Sela , Cameron Piron , Joshua Richmond , Murugathas Yuwaraj , Wes Hodges , Simon Alexander , David Gallop , William Lau , Sheryl Thingvold , Kelly Dyer
IPC分类号： G06F3/0481 , G06T1/60 , A61B19/00 , G06T11/20 , G06F3/0484 , G06T7/00 , G06T17/00
CPC分类号： G06T19/003 , A61B5/0042 , A61B5/055 , A61B6/032 , A61B6/037 , A61B6/501 , A61B8/00 , A61B8/0808 , A61B34/10 , A61B34/20 , A61B2034/105 , A61B2034/107 , A61B2034/2051 , A61B2034/2055 , A61B2090/3735 , A61B2090/378 , G06F3/04815 , G06F3/04842 , G06F3/04847 , G06T1/60 , G06T7/0012 , G06T11/20 , G06T17/00 , G06T19/20 , G06T2200/04 , G06T2200/24 , G06T2207/10088 , G06T2207/20101 , G06T2207/30016 , G06T2207/30241 , G06T2210/41 , G06T2219/028
摘要： Disclosed herein are planning, navigation and simulation systems and methods for minimally invasive therapy in which the planning method and system uses patient specific pre-operative images. The planning system allows for multiple paths to be developed from the pre-operative images, and scores the paths depending on desired surgical outcome of the surgery and the navigation systems allow for minimally invasive port based surgical procedures, as well as craniotomies in the particular case of brain surgery.
摘要翻译：这里公开了用于微创治疗的计划，导航和模拟系统和方法，其中规划方法和系统使用患者特定的术前图像。规划系统允许从术前图像开发多条路径，并根据手术的期望手术结果评估路径，并且导航系统允许基于微创端口的外科手术，以及特定情况下的开颅手术的脑部手术。

12. 发明申请

US20160005169A1 SYSTEM AND METHOD FOR DETECTING TISSUE AND FIBER TRACT DEFORMATION 有权
标题翻译：用于检测组织和纤维束变形的系统和方法
公开(公告)号：US20160005169A1
公开(公告)日：2016-01-07
申请号：US14769507
申请日：2014-03-14
申请人： Gal SELA , Simon ALEXANDER , Cameron PIRON , Joshua RICHMOND , Michael WOOD , Murugathas YUWARAJ , David GALLOP , Wes HODGES , Monrore M. THOMAS
发明人： Gal Sela , Simon Alexander , Cameron Piron , Joshua Richmond , Michael Wood , Murugathas Yuwaraj , David Gallop , Wes Hodges , Monroe M. Thomas
IPC分类号： G06T7/00 , A61B5/00
CPC分类号： G06T7/0012 , A61B5/0066 , A61B5/055 , A61B34/10 , A61B90/11 , A61B2034/105 , G06T2207/30012 , G09B23/30
摘要： Disclosed herein is a method for producing an evolvable tissue model of a patient and, using this model, modelling physical transformations of the tissue (e.g. deformation) of the tissue model by interacting the tissue model with influence models which model interactions with the tissue such as surgical instruments, pressure, swelling, temperature changes etc. The model is produced from a set of input data of the tissue which includes directional information of the tissue. The directional information is used to produce an oriented tissue map. A tissue model is then produced from the oriented tissue map such that the tissue model reflects the directionality of the tissue component. When the tissue model is subjected to an influence that causes tissue deformation over a period of time, the tissue model directionally deforms over the period of time in a manner which reflects a trajectory of the influence interacting with the directionality of the tissue component.
摘要翻译：本文公开了一种用于产生患者的可演化组织模型的方法，并且使用该模型通过将组织模型与模型与组织相互作用的影响模型相互作用来模拟组织模型的物理变化（例如变形），例如手术器械，压力，肿胀，温度变化等。该模型由组织的一组输入数据产生，包括组织的方向信息。方向信息用于产生定向组织图。然后从定向组织图生成组织模型，使得组织模型反映组织成分的方向性。当组织模型受到在一段时间内引起组织变形的影响时，组织模型以反映与组织部件的方向性相互作用的影响的轨迹的方式在一段时间内定向变形。

13. 发明授权

US09922417B2 System and method for detecting tissue and fiber tract deformation 有权
公开(公告)号：US09922417B2
公开(公告)日：2018-03-20
申请号：US14769507
申请日：2014-03-14
申请人： Gal Sela , Simon Alexander , Cameron Piron , Joshua Richmond , Michael Wood , Murugathas Yuwaraj , David Gallop , Wes Hodges , Monroe M. Thomas
发明人： Gal Sela , Simon Alexander , Cameron Piron , Joshua Richmond , Michael Wood , Murugathas Yuwaraj , David Gallop , Wes Hodges , Monroe M. Thomas
IPC分类号： A61B34/10 , A61B90/11 , G06T7/00 , A61B5/00 , G09B23/30 , A61B5/055
CPC分类号： G06T7/0012 , A61B5/0066 , A61B5/055 , A61B34/10 , A61B90/11 , A61B2034/105 , G06T2207/30012 , G09B23/30
摘要： Disclosed herein is a method for producing an evolvable tissue model of a patient and, using this model, modelling physical transformations of the tissue (e.g. deformation) of the tissue model by interacting the tissue model with influence models which model interactions with the tissue such as surgical instruments, pressure, swelling, temperature changes etc. The model is produced from a set of input data of the tissue which includes directional information of the tissue. The directional information is used to produce an oriented tissue map. A tissue model is then produced from the oriented tissue map such that the tissue model reflects the directionality of the tissue component. When the tissue model is subjected to an influence that causes tissue deformation over a period of time, the tissue model directionally deforms over the period of time in a manner which reflects a trajectory of the influence interacting with the directionality of the tissue component.

14. 发明授权

US09019262B2 Systems and methods for tracking positions between imaging modalities and transforming a displayed three-dimensional image corresponding to a position and orientation of a probe 有权
标题翻译：用于跟踪成像模态之间的位置并转换对应于探针的位置和取向的显示的三维图像的系统和方法
公开(公告)号：US09019262B2
公开(公告)日：2015-04-28
申请号：US12954663
申请日：2010-11-25
申请人： Kayan Ma , Gal Sela , Cameron Piron
发明人： Kayan Ma , Gal Sela , Cameron Piron
IPC分类号： G06T15/00 , A61B8/00 , A61B8/08 , A61B8/13
CPC分类号： G06T15/20 , A61B8/13 , A61B8/4245 , A61B8/4281 , A61B8/4455 , A61B8/463 , A61B8/465 , A61B8/466 , A61B8/5238 , G06T3/005 , G06T3/60 , G06T7/0012 , G06T7/13 , G06T7/73 , G06T2207/10136
摘要： Systems and methods are provided for transforming a displayed three-dimensional image corresponding to a position and orientation of a field of view of an imaging probe. A three dimensional image of a tissue in a first co-ordinate space can be displayed. A field of view of an imaging probe in a second co-ordinate space can be configured, where the imaging probe has a plurality of transmitters removably connected to it, the transmitters operable to determine the position and orientation of the field of view relative to the positions of the transmitters in the second co-ordinate space. The first and second co-ordinate spaces can be co-registered, and the position and orientation of the field of view in the second co-ordinate space can be transformed to the first co-ordinate space. The three-dimensional image can be displayed to correspond to the transformed position and orientation of the field of view.
摘要翻译：提供了系统和方法，用于变换与成像探针的视场的位置和取向相对应的显示的三维图像。可以显示第一坐标空间中的组织的三维图像。可以配置第二坐标空间中的成像探针的视野，其中成像探针具有可拆卸地连接到其上的多个发射器，所述发射器可操作以确定相对于视场的视野的位置和取向发射机在第二坐标空间中的位置。可以共同注册第一和第二坐标空间，并且可以将第二坐标空间中的视场的位置和方位转换为第一坐标空间。可以显示三维图像以对应于视场的变换位置和取向。

15. 发明申请

US20110034796A1 APPARATUS AND METHOD FOR SUBSTANTIALLY IMMOBILIZING A BREAST FOR MEDICAL IMAGING PROCEDURE 有权
标题翻译：用于医学成像程序的大豆固定化装置和方法
公开(公告)号：US20110034796A1
公开(公告)日：2011-02-10
申请号：US12851988
申请日：2010-08-06
申请人： Kayan Ma , Gal Sela , Cameron Piron
发明人： Kayan Ma , Gal Sela , Cameron Piron
IPC分类号： A61B5/05
CPC分类号： A61B5/4312 , A61B5/064 , A61B8/0825 , A61B8/0841 , A61B8/4416
摘要： Apparatus and methods are described for substantially immobilizing a breast for use in medical imaging. In an exemplary embodiment, an apparatus for substantially immobilizing a breast is provided, including a first support member connected to a first and second base, the bases capable of engagement with the torso of a patient, the first support member defining an inner area substantially covered by a first membrane. A corresponding second support member, defining a second inner area substantially covered by a second membrane, is engageable to the first support member such that the inner areas are substantially aligned to substantially immobilize a breast, the membranes defining a pocket to receive a breast.
摘要翻译：描述了用于基本上固定乳房以用于医学成像的装置和方法。在一个示例性实施例中，提供了用于基本上固定乳房的装置，包括连接到第一和第二基座的第一支撑构件，能够与患者的躯干接合的基座，第一支撑构件限定内部区域，通过第一膜。限定基本上由第二膜覆盖的第二内部区域的相应的第二支撑构件可接合到第一支撑构件，使得内部区域基本上对准以基本上固定乳房，膜限定了口袋以接收乳房。

16. 发明授权

US08452374B2 Apparatus and method for substantially immobilizing a breast for medical imaging procedure 有权
标题翻译：用于医疗成像程序的用于基本上固定乳房的装置和方法
公开(公告)号：US08452374B2
公开(公告)日：2013-05-28
申请号：US12851988
申请日：2010-08-06
申请人： Kayan Ma , Gal Sela , Cameron Piron
发明人： Kayan Ma , Gal Sela , Cameron Piron
IPC分类号： A61B5/055 , H05G1/00
CPC分类号： A61B5/4312 , A61B5/064 , A61B8/0825 , A61B8/0841 , A61B8/4416
摘要： Apparatus and methods are described for substantially immobilizing a breast for use in medical imaging. In an exemplary embodiment, an apparatus for substantially immobilizing a breast is provided, including a first support member connected to a first and second base, the bases capable of engagement with the torso of a patient, the first support member defining an inner area substantially covered by a first membrane. A corresponding second support member, defining a second inner area substantially covered by a second membrane, is engageable to the first support member such that the inner areas are substantially aligned to substantially immobilize a breast, the membranes defining a pocket to receive a breast.
摘要翻译：描述了用于基本上固定乳房以用于医学成像的装置和方法。在一个示例性实施例中，提供了用于基本上固定乳房的装置，包括连接到第一和第二基座的第一支撑构件，能够与患者的躯干接合的基座，第一支撑构件限定内部区域，通过第一膜。限定基本上由第二膜覆盖的第二内部区域的相应的第二支撑构件可接合到第一支撑构件，使得内部区域基本上对准以基本上固定乳房，膜限定了口袋以接收乳房。

17. 发明申请

US20110134113A1 SYSTEMS AND METHODS FOR TRACKING POSITIONS BETWEEN IMAGING MODALITIES AND TRANSFORMING A DISPLAYED THREE-DIMENSIONAL IMAGE CORRESPONDING TO A POSITION AND ORIENTATION OF A PROBE 有权
标题翻译：用于跟踪成像模式之间的位置的系统和方法，并且与相对于位置和位置的探测器相关的显示的三维图像进行变换
公开(公告)号：US20110134113A1
公开(公告)日：2011-06-09
申请号：US12954663
申请日：2010-11-25
申请人： Kayan Ma , Gal Sela , Cameron Piron
发明人： Kayan Ma , Gal Sela , Cameron Piron
IPC分类号： G06T15/00
CPC分类号： G06T15/20 , A61B8/13 , A61B8/4245 , A61B8/4281 , A61B8/4455 , A61B8/463 , A61B8/465 , A61B8/466 , A61B8/5238 , G06T3/005 , G06T3/60 , G06T7/0012 , G06T7/13 , G06T7/73 , G06T2207/10136
摘要： Systems and methods are provided for transforming a displayed three-dimensional image corresponding to a position and orientation of a field of view of an imaging probe. A three dimensional image of a tissue in a first co-ordinate space can be displayed. A field of view of an imaging probe in a second co-ordinate space can be configured, where the imaging probe has a plurality of transmitters removably connected to it, the transmitters operable to determine the position and orientation of the field of view relative to the positions of the transmitters in the second co-ordinate space. The first and second co-ordinate spaces can be co-registered, and the position and orientation of the field of view in the second co-ordinate space can be transformed to the first co-ordinate space. The three-dimensional image can be displayed to correspond to the transformed position and orientation of the field of view.
摘要翻译：提供了系统和方法，用于变换与成像探针的视场的位置和取向相对应的显示的三维图像。可以显示第一坐标空间中的组织的三维图像。可以配置第二坐标空间中的成像探针的视野，其中成像探针具有可拆卸地连接到其上的多个发射器，所述发射器可操作以确定相对于视场的视野的位置和取向发射机在第二坐标空间中的位置。可以共同注册第一和第二坐标空间，并且可以将第二坐标空间中的视场的位置和方位转换为第一坐标空间。可以显示三维图像以对应于视场的变换位置和取向。

18. 发明申请

US20160000515A1 SYSTEM AND METHOD FOR DYNAMIC VALIDATION, CORRECTION OF REGISTRATION FOR SURGICAL NAVIGATION 审中-公开
标题翻译：用于动态鉴定的系统和方法，用于手术导航的注册更正
公开(公告)号：US20160000515A1
公开(公告)日：2016-01-07
申请号：US14775759
申请日：2014-03-14
申请人： Gal Sels , Cameron Piron , Michael Wood , Joshua Richmond , Murugathas Yuwaraj , Stephen McFadyen , Monroe M. Thomas , Wes Hodges , Simon Alexander
发明人： Gal Sela , Cameron Piron , Michael Wood , Joshua Richmond , Murugathas Yuwaraj , Stephen McFadyen , Monroe M. Thomas , Wes Hodges , Simon Alexander , David Gallop
IPC分类号： A61B19/00
摘要： Disclosed herein is a system and method for dynamic validation, correction of registration for surgical navigation during medical procedures on a patient which involves confirmation of registration between one or more previously registered virtual objects, such as surgical tools etc. in a common coordinate frame of a surgical navigation system and an operating room, and intra-operatively acquired imaging during the medical procedure in the common coordinate frame. The method includes displaying intra-operatively acquired imaging of the surgical field containing the one or more real objects corresponding to the one or more previously registered virtual objects, with the real objects being tracked by a tracking system. The method overlaying a virtual image containing the previously registered virtual objects onto the intra-operatively acquired imaging, from the point of view of the intra-operatively acquired imaging, and detecting for any misalignment between any one of the one or more previously registered virtual objects contained in the virtual image and its corresponding real object contained in the intra-operatively acquired imaging.
摘要翻译：本文公开了一种用于动态验证的系统和方法，用于在患者的医疗过程期间对外科导航的注册进行校正，其涉及确认一个或多个先前登记的虚拟对象之间的注册，诸如外科手术工具等手术导航系统和手术室，以及在公共坐标系中的医疗过程期间的手术内获取的成像。该方法包括显示手术区域的操作中获取的成像，所述成像包含与一个或多个先前注册的虚拟对象相对应的一个或多个实际对象，其中所述实际对象由跟踪系统跟踪。从操作中获取的成像的角度，将包含先前登记的虚拟对象的虚拟图像重叠到操作中获取的成像上的方法，以及检测一个或多个先前注册的虚拟对象中的任何一个之间的任何未对准包含在虚拟图像中及其对应的实际对象中，包含在操作中获取的成像中。

19. 发明授权

US10828104B2 Surgical navigation system using image segmentation 有权
公开(公告)号：US10828104B2
公开(公告)日：2020-11-10
申请号：US15510572
申请日：2014-09-15
申请人： Arun Victor Jagga , Cameron Piron
发明人： Arun Victor Jagga , Cameron Piron
IPC分类号： A61B34/20 , A61B34/00 , A61B90/10 , A61B90/00
摘要： A system for tracking a piece of medical equipment intraoperatively using a collinear array of fiducial markers positioned at known fixed distances relative to each other on the medical equipment and a camera capturing an image on a single image plane. Representations of the fiducial markers are segmented from a captured image, 3D orientation and position of the medical equipment are calculated using the segmented representations, and the orientation and position of the medical equipment are tracked relative to the camera. The orientation and position of the medical equipment may be registered within a 3D virtual space. The system may be used as part of a surgical navigation system.

20. 发明授权

US09913733B2 Intra-operative determination of dimensions for fabrication of artificial bone flap 有权
公开(公告)号：US09913733B2
公开(公告)日：2018-03-13
申请号：US15110161
申请日：2014-08-20
申请人： Cameron Piron , Murugathas Yuwaraj
发明人： Cameron Piron , Murugathas Yuwaraj
IPC分类号： A61F2/46 , A61F2/28 , A61B6/03 , A61B5/00 , A61B5/055 , A61B5/06 , A61B5/107 , A61B34/00 , A61B34/20 , G05B19/4097 , A61F2/30
CPC分类号： A61F2/4601 , A61B5/0035 , A61B5/0037 , A61B5/0042 , A61B5/0066 , A61B5/055 , A61B5/064 , A61B5/1072 , A61B5/1079 , A61B6/03 , A61B6/032 , A61B6/037 , A61B6/505 , A61B6/5229 , A61B8/0841 , A61B17/00491 , A61B17/0642 , A61B17/86 , A61B34/00 , A61B34/10 , A61B34/20 , A61B2034/104 , A61B2034/105 , A61B2034/107 , A61B2034/108 , A61B2034/2051 , A61B2034/2055 , A61B2034/2065 , A61B2034/2068 , A61B2090/363 , A61B2090/365 , A61B2090/3735 , A61F2/28 , A61F2/2875 , A61F2/30942 , A61F2/46 , A61F2002/2835 , A61F2002/30948 , A61F2002/4632 , G05B19/4097 , G05B2219/35134 , G05B2219/49007
摘要： Methods and systems for calculating dimensions for fabricating an artificial bone flap. Intra-operative data indicating dimensions of an opening in a portion of the patient's skull are obtained. 3D dimensions of the opening are calculated using the intra-operative data, registered to a reference image. The calculated 3D dimensions are provided for fabricating the artificial bone flap by a fabrication system.

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