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11. 发明申请

US20080125674A1 Catheter Guide Wire, in Particular for Cardiovascular interventions 审中-公开
标题翻译：导管指南，特别是心血管介入治疗
公开(公告)号：US20080125674A1
公开(公告)日：2008-05-29
申请号：US11570182
申请日：2005-05-19
申请人： Deniz Bilecen , Eugen Hofmann , Wladimir Ostheim-Dzerowycz
发明人： Deniz Bilecen , Eugen Hofmann , Wladimir Ostheim-Dzerowycz
IPC分类号： A61M25/09
CPC分类号： A61M25/09 , A61L31/06 , A61L31/18 , A61M2025/09091 , A61M2025/09166 , C08L71/00
摘要： The invention relates to a catheter guide wire comprising a PEEK core (e) that is provided with a coating (6). The core (4) extends in one piece from the proximal end to the distal end (3, 2) of the guide wire 81) and tapers towards the distal end (2). The coating (6) is provided with a contrast medium (7).
摘要翻译：本发明涉及一种导管导丝，其包括设置有涂层（6）的PEEK芯（e）。芯部（4）从导丝81的近端延伸到远端（3,2）并且朝着远端（2）逐渐变细。涂层（6）设置有造影剂（7）。

12. 发明授权

US5919204A Apparatus for releasing a self-expanding endoprosthesis 失效
标题翻译：用于释放自膨胀内置假体的装置
公开(公告)号：US5919204A
公开(公告)日：1999-07-06
申请号：US249821
申请日：1994-05-26
申请人： Goran Lukic , Eugen Hofmann
发明人： Goran Lukic , Eugen Hofmann
IPC分类号： A61B17/00 , A61F2/06 , A61F2/84 , A61M29/00
CPC分类号： A61F2/95 , A61F2/966
摘要： When installed in the device, the endoprosthesis is compressed radially and located in a cylindrical chamber (14), one proximal area (A) of this endoprosthesis lies within a first outer catheter (3) and a second distal area (B) is in a second outer catheter (30). In order to release the endoprosthesis (1) in a vessel (11), for example, the second outer catheter (30) is first retracted. The endoprosthesis (1) is then held in the first outer catheter (3) by friction and can be re-folded and thus repositioned by advancing the second outer catheter (30). Finally, the endoprosthesis (1) is released by retracting the first outer catheter (3). Because the friction is distributed over at least two outer catheters (3, 30), even endoprostheses (1) that generate a high level of friction on the outer catheter, for example because of a coating, of greater expansion force, or because of great length, can be released.
摘要翻译：当安装在装置中时，内假体被径向地压缩并且位于圆柱形腔室（14）中，该内用假体的一个近侧区域（A）位于第一外导管（3）内，第二远端区域（B）处于第二外导管（30）。为了在容器（11）中释放内用假体（1），例如，第一外导管（30）首先缩回。内置假体（1）然后通过摩擦保持在第一外导管（3）中，并且可以通过前进第二外导管（30）被重新折叠并因此重新定位。最后，通过缩回第一外导管（3）来释放内假体（1）。因为摩擦分布在至少两个外部导管（3,30）上，甚至是在外部导管上产生高水平摩擦的假体内（1），例如由于涂层而具有较大的膨胀力，或者由于较大的膨胀力长度，可以释放。

13. 发明授权

US08337548B2 Implant and system of an implant and an excitation device 有权
标题翻译：植入物和植入物和激发装置的系统
公开(公告)号：US08337548B2
公开(公告)日：2012-12-25
申请号：US12171566
申请日：2008-07-11
申请人： Bjoern Klocke , Matthias Fringes , Eugen Hofmann
发明人： Bjoern Klocke , Matthias Fringes , Eugen Hofmann
IPC分类号： A61F2/06 , A61F2/48 , A61K9/22
CPC分类号： A61M31/002 , A61F2/82 , A61F2/91 , A61F2210/0071 , A61F2250/0001 , A61F2250/0068
摘要： An implant comprising a body (1), at least one active pharmaceutical substance (4) and an element (5, 15, 35, 45, 55) deflectable in relation to the body, serving to release the at least one active pharmaceutical substance (4) during or after an external excitation of the deflection. Also disclosed is a system of such an implant and an excitation device (30, 70).
摘要翻译：包括主体（1），至少一种活性药物物质（4）和相对于身体可偏转的元件（5,15,35,45,55）的植入体，其用于释放所述至少一种活性药物物质（ 4）在外部激发偏转期间或之后。还公开了这种植入物和激励装置（30,70）的系统。

14. 发明申请

US20050267385A1 Catheter guide wire especially for percutaneous transluminal coronary angioplasty 有权
标题翻译：导管导丝专用于经皮腔内冠状动脉成形术
公开(公告)号：US20050267385A1
公开(公告)日：2005-12-01
申请号：US11125309
申请日：2005-05-10
申请人： Eugen Hofmann , Christoph Wintsch
发明人： Eugen Hofmann , Christoph Wintsch
IPC分类号： A61B5/00 , A61M25/01 , A61M25/09 , A61M25/095
CPC分类号： A61M25/09 , A61M25/0108 , A61M2025/09166
摘要： A catheter guide wire, especially for percutaneous transluminal coronary angioplasty, comprises an elongated wire shaft of a flexible material having a proximal and a distal end and disposed on the wire shaft at least one radiopaque, sleeve-like marker adjacent to the distal end. The at least one marker is disposed on a core section of the wire shaft, said core section being widened in its diameter relative to the diameter of the adjoining shaft sections.
摘要翻译：特别是用于经皮腔内冠状动脉血管成形术的导管导丝包括具有近端和远端的柔性材料的细长线轴，并且在线轴上设置有与远端相邻的至少一个不透射线的套筒状标记。所述至少一个标记设置在所述线轴的芯部上，所述芯部相对于邻接的轴部的直径在其直径上变宽。

15. 发明授权

US06295714B1 Process for fabricating a prosthesis 有权
标题翻译：制造假体的方法
公开(公告)号：US06295714B1
公开(公告)日：2001-10-02
申请号：US09510209
申请日：2000-02-22
申请人： Suranjan Roychowdhury , Leonard Pinchuk , Eugen Hofmann , Susanne Hankh , Michael G. O'Connor , Jennifer E. Raeder-Devens , Jeannine B. Baden , Daniel J. Klima
发明人： Suranjan Roychowdhury , Leonard Pinchuk , Eugen Hofmann , Susanne Hankh , Michael G. O'Connor , Jennifer E. Raeder-Devens , Jeannine B. Baden , Daniel J. Klima
IPC分类号： B21D3900
CPC分类号： A61F2/90 , A61F2/958 , A61F2002/30451 , A61F2002/9522 , A61F2220/0058 , A61F2240/001 , Y10T29/49798 , Y10T29/49927
摘要： A body implantable stent is formed of a plurality of strands arranged in two sets of coaxial helices, wound in opposite directions to form multiple crossings. At selected crossings, the adjacent strands are welded to one another, while at the remaining crossings the strands are free for limited movement relative to one another. The welds are formed in patterns that preferably enhance radial strength and rigidity, while having a minimal impact on axial bending flexibility. Preferred weld patterns in this regard include rings or circumferential rows, and helices, particularly with a steeper pitch than that of the strands. Stent fabrication preferably involves resistance welding at the crossings, and use of a tool to reuniformly compress the stent around and against the distal end region of a balloon catheter used later to deliver the stent to a treatment site.
摘要翻译：身体可植入支架由多个绞合线构成，所述股线布置成两组同轴螺旋，沿相反方向缠绕以形成多个交叉。在所选的交叉处，相邻的线条彼此焊接，而在剩余的交叉处，线条相对于彼此有限的移动是自由的。焊缝以优选增强径向强度和刚度的图案形成，同时对轴向弯曲柔性具有最小的影响。在这方面，优选的焊接图案包括环或周向排和螺旋，特别是具有比线的陡峭的间距。支架制造优选地涉及在交叉点处的电阻焊接，以及使用工具将支架均匀地压缩在球囊导管的远端区域周围并抵靠以后用于将支架输送到治疗部位的远端区域。

16. 发明授权

US5725571A Catheter with a stent 失效
标题翻译：导管与支架
公开(公告)号：US5725571A
公开(公告)日：1998-03-10
申请号：US752273
申请日：1996-11-20
申请人： Christian Imbert , Eugen Hofmann , Marc Gianotti
发明人： Christian Imbert , Eugen Hofmann , Marc Gianotti
IPC分类号： A61M25/00 , A61F2/90 , A61M27/00 , A61F2/06 , A61M29/00
CPC分类号： A61F2/95 , A61F2/90 , A61F2/966
摘要： A catheter with a self-expanding stent of a permeable mesh of stiff intersecting fibers is provided. A tubular outer catheter shaft holds the stent under tension at its distal end and from which the stent can be released for placement. A displaceable inner catheter inside the tubular outer catheter shaft supports the stent axially at its proximal end. In order to release the stent, the outer catheter shaft is retracted with respect to the inner catheter. A process for producing this catheter is also described. The stent is secured by gripping it at its proximal end in such a way that it forms a permeable mesh cone that expands automatically together with the stent and has a radius that increases gradually to the radius of the relaxed stent. The stent is securely anchored on the inner catheter with the help of the mesh cone.
摘要翻译：提供了具有刚性交叉纤维的可渗透网的自膨胀支架的导管。管状外导管轴将支架保持在其远端处的张力处，并且支架可以从该导管释放以放置。管状外导管轴内的位移内导管在其近端轴向支撑支架。为了释放支架，外导管轴相对于内导管缩回。还描述了用于生产该导管的方法。通过在其近端处夹持支架来固定支架，使得其形成与支架一起自动扩张的可渗透的网孔，并且具有逐渐增加到松弛支架的半径的半径。借助于网孔，支架可靠地固定在内导管上。

17. 发明授权

US5607466A Catheter with a stent 失效
标题翻译：导管与支架
公开(公告)号：US5607466A
公开(公告)日：1997-03-04
申请号：US433281
申请日：1995-04-28
申请人： Christian Imbert , Eugen Hofmann , Marc Gianotti
发明人： Christian Imbert , Eugen Hofmann , Marc Gianotti
IPC分类号： A61M25/00 , A61F2/90 , A61M27/00 , A61F2/06 , A61M5/178 , A61M29/00
CPC分类号： A61F2/95 , A61F2/90 , A61F2/966
摘要： A catheter with a self-expanding stent of a permeable mesh of stiff intersecting fibers is provided. A tubular outer catheter shaft holds the stent under tension at its distal end and from which the stent can be released for placement. A displaceable inner catheter inside the tubular outer catheter shaft supports the stent axially at its proximal end. In order to release the stent, the outer catheter shaft is retracted with respect to the inner catheter. A process for producing this catheter is also described. The stent is secured by gripping it at its proximal end in such a way that it forms a permeable mesh cone that expands automatically together with the stent and has a radius that increases gradually to the radius of the relaxed stent. The stent is securely anchored on the inner catheter with the help of the mesh cone.
摘要翻译：提供了具有刚性交叉纤维的可渗透网的自膨胀支架的导管。管状外导管轴将支架保持在其远端处的张力处，并且支架可以从该导管释放以放置。管状外导管轴内部的位移内导管在其近端轴向支撑支架。为了释放支架，外导管轴相对于内导管缩回。还描述了用于生产该导管的方法。通过在其近端处夹持支架来固定支架，使得其形成与支架一起自动扩张的可渗透的网孔，并且具有逐渐增加到松弛支架的半径的半径。借助于网孔，支架可靠地固定在内导管上。

18. 发明申请

US20100121312A1 Catheter Shaft 审中-公开
标题翻译：导管轴
公开(公告)号：US20100121312A1
公开(公告)日：2010-05-13
申请号：US12613469
申请日：2009-11-05
申请人： Gerhard Gielenz , Eugen Hofmann
发明人： Gerhard Gielenz , Eugen Hofmann
IPC分类号： A61M25/00 , B29C53/58
CPC分类号： A61M25/0009 , A61M25/0043 , A61M25/005
摘要： The invention relates to a method for the production of at least one longitudinal section of a catheter, wherein the method comprises the winding of film, and the film is provided in the form of strips, the film strip is wound in the manner of a screw such that the side edges of the film strip extending in the manner of a thread overlap the film strip, and further a bonded connection is created in the overlapping region such that the longitudinal section has a closed and at least fluid-tight surface. The invention further relates to a catheter produced according to the method, and a device for carrying out the method.
摘要翻译：本发明涉及一种用于生产导管的至少一个纵向截面的方法，其中该方法包括卷绕薄膜，薄膜以带状的形式提供，薄膜条以螺钉的方式缠绕使得以线的方式延伸的膜条的侧边缘与膜条重叠，并且在重叠区域中还形成粘合连接，使得纵向部分具有封闭且至少是流体密封的表面。本发明还涉及根据该方法制造的导管和用于执行该方法的装置。

19. 发明申请

US20100010615A1 INSERTION SYSTEM FOR A MEDICAL DEVICE HAVING A SHEATH AND SHEATH FOR AN INSERTION SYSTEM FOR A MEDICAL DEVICE 审中-公开
标题翻译：具有用于医疗装置的插入系统的护理和护理的医疗装置的插入系统
公开(公告)号：US20100010615A1
公开(公告)日：2010-01-14
申请号：US12495927
申请日：2009-07-01
申请人： Eugen Hofmann , Daniel Lootz
发明人： Eugen Hofmann , Daniel Lootz
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2/88 , A61F2002/30024 , A61F2250/0021
摘要： An insertion system (100) for a medical device (10), which is situated in an outer sheath (20) upon insertion, the outer sheath (20) at least regionally encompassing an inner shaft. The outer sheath (20) at least regionally has, at least on its inner side (29) facing toward the medical device (10), a structure (22, 32) which is complementary with an external-peripheral segmented structure (12) of the medical device (10) like a bolt-nut connection.
摘要翻译：一种用于医疗装置（10）的插入系统（100），其在插入时位于外护套（20）中，所述外护套（20）至少在区域上包围内轴。至少在至少在其内侧（29）面向医疗装置（10）的区域上，外护套（20）至少具有与外周分段结构（12）互补的结构（22,32）该医疗装置（10）类似螺栓 - 螺母连接。

20. 发明申请

US20090227901A1 CATHETER GUIDEWIRE AND METHOD FOR MANUFACTURING SAME 审中-公开
标题翻译：导管指南及其制造方法
公开(公告)号：US20090227901A1
公开(公告)日：2009-09-10
申请号：US12398732
申请日：2009-03-05
申请人： Eugen Hofmann
发明人： Eugen Hofmann
IPC分类号： A61M25/01
CPC分类号： A61M25/09 , A61M25/0045 , A61M25/0127 , A61M2025/09075 , A61M2025/09108 , A61M2025/09191
摘要： A catheter guidewire (1), preferably for cardiovascular procedures, having a distal end (2) and a proximal end (3) and a one-piece core (10) extending essentially from the distal end to the proximal end. The one-piece core has twisted fibers, preferably glass fibers, which are embedded in the basic material of the core. Also disclosed is a method for manufacturing a catheter guidewire.
摘要翻译：导管导丝（1），优选用于心血管程序，具有远端（2）和近端（3）以及基本上从远端延伸到近端延伸的一体式芯（10）。一体式芯具有嵌入在芯的基本材料中的扭曲纤维，优选玻璃纤维。还公开了一种制造导管导丝的方法。

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