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11. 发明申请

US20090228100A1 Methods and Devices for Heart Valve Repair 审中-公开
标题翻译：心脏瓣膜修复的方法和设备
公开(公告)号：US20090228100A1
公开(公告)日：2009-09-10
申请号：US12471203
申请日：2009-05-22
申请人： Jan Otto Solem , Per Ola Kimblad , Stevan Nielsen , Ib Joergenson , Bodo Quint , Gerd Seibold , Randolf Von Oepen , Suk-Woo Ha , Karl-Ludwig Eckert , Stefan Schreck , Sepehr Fariabi , Tommy Conzelmann
发明人： Jan Otto Solem , Per Ola Kimblad , Stevan Nielsen , Ib Joergenson , Bodo Quint , Gerd Seibold , Randolf Von Oepen , Suk-Woo Ha , Karl-Ludwig Eckert , Stefan Schreck , Sepehr Fariabi , Tommy Conzelmann
IPC分类号： A61F2/24
CPC分类号： A61F2/2451
摘要： An elongate body including a proximal and distal anchor, and a bridge between the proximal and distal anchors. The bridge has an elongated state, having first axial length, and a shortened state, having a second axial length, wherein the second axial length is shorter than the first axial length. A resorbable thread may be woven into the bridge to hold the bridge in the elongated state and to delay the transfer of the bridge to the shortened state. In an additional embodiment, there may be one or more central anchors between the proximal and distal anchors with a bridge connecting adjacent anchors.
摘要翻译：包括近端和远端锚固件的细长主体以及近端和远端锚固件之间的桥梁。桥具有第一轴向长度的细长状态和具有第二轴向长度的缩短状态，其中第二轴向长度短于第一轴向长度。可再吸收的线可以编织到桥中以将桥梁保持在细长状态，并且将桥的传递延迟到缩短状态。在另外的实施例中，在近端和远端锚固件之间可以有一个或多个中心锚固件，其具有连接相邻锚固件的桥。

12. 发明授权

US07258753B2 Superelastic guiding member 失效
公开(公告)号：US07258753B2
公开(公告)日：2007-08-21
申请号：US10688401
申请日：2003-10-16
申请人： Robert M. Abrams , Sepehr Fariabi
发明人： Robert M. Abrams , Sepehr Fariabi
IPC分类号： A61F2/86
CPC分类号： A61L31/14 , A61L31/022 , A61L2400/16 , A61M25/09 , A61M2025/09008 , A61M2025/09083 , A61M2025/09141 , A61M2025/09175 , A61M2205/0266 , C22C14/00 , C22C30/00 , C22F1/006
摘要： An improved guiding member for use within a body lumen having a unique combination of superelastic characteristics. The superelastic alloy material has a composition consisting of about 30% to about 52% (atomic) titanium, and about 38% to 52% nickel and may have one or more elements selected from the group consisting of iron, cobalt, platinum, palladium, vanadium, copper, zirconium, hafnium and niobium. The alloy material is subjected to thermomechanical processing which includes a final cold working of about 10 to about 75% and then a heat treatment at a temperature between about 450° and about 600° C. and preferably about 475° to about 550° C. Before the heat treatment the cold worked alloy material is preferably subjected to mechanical straightening. The alloy material is preferably subjected to stresses equal to about 5 to about 50% of the room temperature ultimate yield stress of the material during the thermal treatment. The guiding member using such improved material exhibits a stress-induced austenite-to-martensite phase transformation at an exceptionally high constant yield strength of over 90 ksi for solid members and over 70 ksi for tubular members with a broad recoverable strain of at least about 4% during the phase transformation. An essentially whip free product is obtained.

13. 发明授权

US06878155B2 Method of treating intervertebral disc tissue employing attachment mechanism 失效
标题翻译：使用连接机制治疗椎间盘组织的方法
公开(公告)号：US06878155B2
公开(公告)日：2005-04-12
申请号：US09884859
申请日：2001-06-18
申请人： Hugh R. Sharkey , Sepehr Fariabi , John Ashley , Joel Saal , Jeffrey Saal
发明人： Hugh R. Sharkey , Sepehr Fariabi , John Ashley , Joel Saal , Jeffrey Saal
IPC分类号： A61B18/20 , A61B17/00 , A61B17/16 , A61B17/22 , A61B17/34 , A61B17/56 , A61B18/00 , A61B18/04 , A61B18/12 , A61B18/18 , A61M25/00 , A61M25/01 , A61F7/00 , A61F2/00
CPC分类号： A61B17/1671 , A61B17/3421 , A61B2017/00261 , A61B2017/003 , A61B2017/22044 , A61B2017/22049 , A61B2017/3488 , A61M25/0084 , A61M25/09
摘要： Apparatus and methods are disclosed for accessing the interior of an intervertebral disc to perform a function within the disc. One such apparatus comprises a catheter having a lumen; and a guide wire having a distal portion and a proximal portion, and configured to be positioned within and moved relative to the lumen of the catheter; wherein the guide wire is capable of navigating itself within an intradiscal section of the intervertebral disc to a selected section of the disc and the catheter is capable of being advanced relative to the guide wire such that the catheter follows a path of the guide wire within the intradiscal section of the disc to the selected section. These apparatus and methods may be used for the treatment of intervertebral disc disorders such as sealing fissures of the annulus fibrosus, which may or may not be accompanied with contained or escaped extrusions. These apparatus and methods may also be used, for example, for the removal or addition of material to the intervertebral disc.
摘要翻译：公开了用于访问椎间盘内部以执行椎间盘内的功能的装置和方法。一种这样的装置包括具有内腔的导管; 以及导线，其具有远侧部分和近端部分，并且构造成定位在所述导管的内腔内并相对于所述导管的内腔移动; 其中所述导丝能够在椎间盘的椎间盘内段内自身导航到所述盘的选定部分，并且所述导管能够相对于所述导丝前进，使得所述导管沿着所述导丝的路径盘片的椎间盘内部分到选定的部分。这些装置和方法可以用于治疗椎间盘疾病，例如纤维环纤维的密封裂缝，其可能伴随着包含或逃逸的挤出物，也可能不伴随其中。这些装置和方法也可以用于例如去除或添加到椎间盘的材料。

14. 发明授权

US06827734B2 High strength member for intracorporeal use 失效
标题翻译：用于体内使用的高强度成员
公开(公告)号：US06827734B2
公开(公告)日：2004-12-07
申请号：US10154474
申请日：2002-05-23
申请人： Sepehr Fariabi
发明人： Sepehr Fariabi
IPC分类号： A61F206
CPC分类号： A61M25/0012 , A61F2/958 , A61F2210/0019 , A61M25/0009 , A61M25/09 , A61M2025/09083
摘要： This invention is directed to an intracorporeal device formed of a high strength Co—Ni—Cr alloy and is particularly suitable for forming a composite product with a pseudoelastic member formed of NiTi alloy. Suitable intracorporeal products include guidewires and stents. The high strength alloy consists essentially of about 28 to about 65% cobalt, about 2 to about 40% nickel, about 5 to about 35% chromium, up to about 12% molybdenum, up to about 20% tungsten, up to about 20% iron and the balance inconsequential amounts of impurities and other alloying constituents, with a preferred alloy composition including about 30 to about 45% cobalt, about 25 to about 37% nickel, about 15 to about 25% chromium and about 5 to about 15% molybdenum. Intravascular devices such as guidewires, stents and the like can be formed of this high strength Co—Ni—Cr alloy.
摘要翻译：本发明涉及由高强度Co-Ni-Cr合金形成的体内器件，特别适用于形成具有由NiTi合金形成的假弹性体的复合产品。合适的体内产品包括导线和支架。高强度合金主要由约28至约65％的钴，约2-约40％的镍，约5-35％的铬，至多约十二％的钼，至多约20％的钨，至多约20％铁和余量是无关的量的杂质和其他合金成分，优选的合金组成包括约30至约45％的钴，约25至约37％的镍，约15至约25％的铬和约5至约15％的钼。诸如导线，支架等的血管内装置可以由这种高强度Co-Ni-Cr合金形成。

15. 发明授权

US06482166B1 High strength member for intracorporeal use 失效
标题翻译：用于体内使用的高强度成员
公开(公告)号：US06482166B1
公开(公告)日：2002-11-19
申请号：US08829465
申请日：1997-03-28
申请人： Sepehr Fariabi
发明人： Sepehr Fariabi
IPC分类号： A61B500
CPC分类号： A61M25/0012 , A61F2/958 , A61F2210/0019 , A61M25/0009 , A61M25/09 , A61M2025/09083
摘要： This invention is directed to an intracorporeal device formed of a high strength Co—Ni—Cr alloy and is particularly suitable for forming a composite product with a pseudoelastic member formed of NiTi alloy. Suitable intracorporeal products include guidewires and stents. The high strength alloy consists essentially of about 28 to about 65% cobalt, about 2 to about 40% nickel, about 5 to about 35% chromium, up to about 12% molybdenum, up to about 20% tungsten, up to about 20% iron and the balance inconsequential amounts of impurities and other alloying constituents, with a preferred alloy composition including about 30 to about 45% cobalt, about 25 to about 37% nickel, about 15 to about 25% chromium and about 5 to about 15% molybdenum. Intravascular devices such as guidewires, stents and the like can be formed of this high strength Co—Ni—Cr alloy.
摘要翻译：本发明涉及由高强度Co-Ni-Cr合金形成的体内器件，特别适用于形成具有由NiTi合金形成的假弹性体的复合产品。合适的体内产品包括导线和支架。高强度合金主要由约28至约65％的钴，约2-约40％的镍，约5-35％的铬，至多约十二％的钼，至多约20％的钨，至多约20％铁和余量是无关的量的杂质和其他合金成分，优选的合金组成包括约30至约45％的钴，约25至约37％的镍，约15至约25％的铬和约5至约15％的钼。诸如导线，支架等的血管内装置可以由这种高强度Co-Ni-Cr合金形成。

16. 发明授权

US06287292B1 Guidewire with a variable stiffness distal portion 有权
标题翻译：导丝具有可变刚度远端部分
公开(公告)号：US06287292B1
公开(公告)日：2001-09-11
申请号：US09287703
申请日：1999-04-06
申请人： Sepehr Fariabi
发明人： Sepehr Fariabi
IPC分类号： A61M2500
CPC分类号： A61M25/0158 , A61M25/09 , A61M2025/09141 , A61M2025/09175
摘要： A guidewire having a core section formed of a NiTi alloy which is in an austenite phase when being manufactured but which is converted to the martensite phase at operating (body) temperature (37° C.) and can be transformed to an austenite phase by heating to a temperature above body temperature but below 50° C. When in the austenite phase, the core section is at a high strength level which ensures the tracking of a catheter over the guidewire within a patient's body lumen. In one preferred embodiment the core section is heated by electrical resistance or inductance.
摘要翻译：导丝，其具有由NiTi合金形成的芯部，该NiTi合金在制造时处于奥氏体相，但在工作（体）温度（37℃）下转变为马氏体相，并且可以通过加热转变为奥氏体相到超过体温但低于50℃的温度。当在奥氏体相中时，芯部分处于高强度水平，这确保导管在患者体腔内的导丝上的跟踪。在一个优选实施例中，芯部被电阻或电感加热。

17. 发明授权

US07806928B2 Diagnostic kit to assist with heart valve annulus adjustment 有权
标题翻译：诊断套件，以协助心脏瓣膜环调整
公开(公告)号：US07806928B2
公开(公告)日：2010-10-05
申请号：US11689310
申请日：2007-03-21
申请人： Stanton J. Rowe , Henry Bourang , Sepehr Fariabi , Jan Otto Solem
发明人： Stanton J. Rowe , Henry Bourang , Sepehr Fariabi , Jan Otto Solem
IPC分类号： A61F2/24
CPC分类号： A61F2/2451 , A61B1/00082 , A61B5/064 , A61B8/06 , A61B8/12
摘要： A diagnostic device for determining the amount of change required in a coronary sinus to reduce valve regurgitation. The device includes a distal tube having a distal anchor at a distal end portion of the distal tube, a proximal tube having a proximal anchor at a distal end portion of the proximal tube, and an adjustor to move the distal tube relative to the proximal tube. The proximal tube and the distal tube together form a telescoping elongate body adapted to fit within the coronary sinus, and the device includes a scale to measure the movement of the distal anchor relative to the proximal anchor.
摘要翻译：用于确定冠状窦所需的变化量以减少瓣膜反流的诊断装置。该装置包括远端管，远侧管位于远端管的远端部分处，近端管具有位于近端管的远端部分处的近端锚固件，以及用于相对于近端管移动远侧管的调节器。近端管和远端管一起形成适于装配在冠状窦内的伸缩式细长体，并且该装置包括用于测量远端锚固体相对于近端锚的运动的标尺。

18. 发明申请

US20080255581A1 SHORT SLEEVE STENT DELIVERY CATHETER AND METHODS 审中-公开
标题翻译：短袖运输导管和方法
公开(公告)号：US20080255581A1
公开(公告)日：2008-10-16
申请号：US12140900
申请日：2008-06-17
申请人： Henry Bourang , Gil M. Vardi , Eric Williams , Sepehr Fariabi , Udayan Patel , Javier Sagastegui
发明人： Henry Bourang , Gil M. Vardi , Eric Williams , Sepehr Fariabi , Udayan Patel , Javier Sagastegui
IPC分类号： A61F2/84
CPC分类号： A61F2/958 , A61F2/856 , A61F2/954
摘要： A stent delivery catheter comprises a catheter body having a proximal end, a distal end, and a guidewire lumen extending from the distal end to at least part way between the proximal end and the distal end. A balloon is disposed over the catheter body near the distal end, and a stent is positioned over the balloon. The stent has a proximal end, a distal end, and a side opening between the proximal end and the distal end. A side sheath is coupled to the catheter body and has a proximal end, a distal end, and a guidewire lumen extending between the proximal end and the distal end. The proximal end of the side sheath is located between the proximal end of the catheter body and the balloon, and the side sheath exits out of the side opening of the stent.
摘要翻译：支架输送导管包括具有近端，远端和从远端延伸到近端和远端之间至少部分方向的导丝管的导管主体。气囊在远端附近设置在导管主体上方，支架位于气囊上方。支架具有近端，远端和在近端和远端之间的侧开口。侧护套耦合到导管主体并且具有近端，远端和在近端和远端之间延伸的导丝管腔。侧护套的近端位于导管主体的近端和气囊之间，侧鞘从支架的侧开口离开。

19. 发明申请

US20080097591A1 DRUG-DELIVERY ENDOVASCULAR STENT AND METHOD OF USE 审中-公开
标题翻译：药物递送内支架及其使用方法
公开(公告)号：US20080097591A1
公开(公告)日：2008-04-24
申请号：US11751268
申请日：2007-05-21
申请人： Douglas R. Savage , John E. Shulze , Ronald E. Betts , Sepehr Fariabi , Shih-Horng Su
发明人： Douglas R. Savage , John E. Shulze , Ronald E. Betts , Sepehr Fariabi , Shih-Horng Su
IPC分类号： A61F2/06
CPC分类号： A61L31/16 , A61F2/82 , A61F2/848 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91541 , A61F2002/91566 , A61F2210/0004 , A61F2210/0014 , A61F2220/0025 , A61F2230/0013 , A61F2240/001 , A61F2250/0023 , A61F2250/0025 , A61F2250/0026 , A61F2250/0036 , A61F2250/0037 , A61F2250/0051 , A61F2250/0067 , A61F2250/0068 , A61F2250/0096 , A61L31/022 , A61L31/10 , A61L2300/416 , A61L2300/606 , A61L2420/02
摘要： An improvement in drug-eluting stents, and method of their making are disclosed. The surface of a metal stent is roughened to have a surface roughness of at least about 20 μin (0.5 μm) and a surface roughness range of between about 300-700 μin (7.5-17.5 μm). The roughened stent surface is covered with a polymer-free coating of a limus drug, to a coating thickness greater than the range of surface roughness of the roughened stent surface.
摘要翻译：披露了药物洗脱支架的改进及其制作方法。金属支架的表面被粗糙化以具有至少约20微米（0.5μm）的表面粗糙度和约300-700μ（7.5-17.5μm）之间的表面粗糙度范围。粗糙化的支架表面覆盖有无聚合物的斜肌药物涂层，涂层厚度大于粗糙化支架表面的表面粗糙度范围。

20. 发明授权

US07211110B2 Diagnostic kit to assist with heart valve annulus adjustment 有权
标题翻译：诊断套件，以协助心脏瓣膜环调整
公开(公告)号：US07211110B2
公开(公告)日：2007-05-01
申请号：US11008055
申请日：2004-12-09
申请人： Stanton J. Rowe , Henry Bourang , Sepehr Fariabi , Jan Otto Solem
发明人： Stanton J. Rowe , Henry Bourang , Sepehr Fariabi , Jan Otto Solem
IPC分类号： A61F2/24
CPC分类号： A61F2/2451 , A61B1/00082 , A61B5/064 , A61B8/06 , A61B8/12
摘要： A diagnostic device for determining the amount of change required in a coronary sinus to reduce valve regurgitation. The device includes a distal tube having a distal anchor at a distal end portion of the distal tube, a proximal tube having a proximal anchor at a distal end portion of the proximal tube, and an adjustor to move the distal tube relative to the proximal tube. The proximal tube and the distal tube together form a telescoping elongate body adapted to fit within the coronary sinus, and the device includes a scale to measure the movement of the distal anchor relative to the proximal anchor.
摘要翻译：用于确定冠状窦所需的变化量以减少瓣膜反流的诊断装置。该装置包括远端管，远侧管位于远端管的远端部分处，近端管具有位于近端管的远端部分处的近端锚固件，以及用于相对于近端管移动远侧管的调节器。近端管和远端管一起形成适于装配在冠状窦内的伸缩式细长体，并且该装置包括用于测量远端锚固体相对于近端锚的运动的标尺。

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