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11. 发明授权

US08727993B2 Apparatuses comprising catheter tips, including mechanically scanning ultrasound probe catheter tip 有权
标题翻译：包括导管尖端的装置，包括机械扫描超声探针导管尖端
公开(公告)号：US08727993B2
公开(公告)日：2014-05-20
申请号：US11624344
申请日：2007-01-18
申请人： Warren Lee , Weston Blaine Griffin , Douglas Glenn Wildes
发明人： Warren Lee , Weston Blaine Griffin , Douglas Glenn Wildes
IPC分类号： A61B8/14
CPC分类号： A61B8/4461 , A61B8/12 , A61B8/445 , A61B8/4488 , A61B8/483
摘要： A catheter tip (50, 170, 750) is provided that is adapted for mating attachment to a catheter body (90, 300, 790). In an embodiment, the catheter tip (50, 170, 750) comprises a transducer array (32, 60, 110, 210, 710) in electrical communication with an interconnect (120, 220, 720) and in a mechanical driven relationship with an actuator (80, 730), also in the catheter tip (50, 170, 750), via a drive shaft (38, 82, 732). The transducer array (710) is encapsulated in a potting material body 711 providing a desired ultrasound acoustical transmission, A defined annular space 761 exists between an outer capsule 752 of the catheter tip 750 and the potting material body 711. Oscillating back and forth motion of the transducer array (32, 60, 110, 210, 710) provides ultrasonic imaging functionality that may include real time three-dimensional imaging. Other embodiments of the catheter tip (50, 170, 750) and methods of fabrication also are provided.
摘要翻译：提供了适于与导管主体（90,300,790）配合的导管尖端（50,170,750）。在一个实施例中，导管尖端（50,170,750）包括与互连（120,220,720）电连通并且与机械驱动关系的换能器阵列（32,60,110,210,710）致动器（80,730），也通过驱动轴（38,82,732）在导管尖端（50,170,750）中。传感器阵列（710）被封装在灌封材料主体711中，提供期望的超声波传播。定义的环形空间761存在于导管尖端750的外部胶囊752和灌封材料主体711之间。振荡来回运动换能器阵列（32,60,110,210,710）提供可包括实时三维成像的超声成像功能。还提供了导管尖端（50,170,750）的其它实施例和制造方法。

12. 发明授权

US08360982B2 Method and apparatus for operating a micromotor in a fluid using a moisture barrier 有权
标题翻译：使用湿气屏障来操作流体中的微型马达的方法和装置
公开(公告)号：US08360982B2
公开(公告)日：2013-01-29
申请号：US12315747
申请日：2008-12-05
申请人： Warren Lee , Douglas Glenn Wildes , Weston Blaine Griffin
发明人： Warren Lee , Douglas Glenn Wildes , Weston Blaine Griffin
IPC分类号： A61B8/12 , A61M25/00
CPC分类号： A61M25/0082 , A61B8/12 , A61B8/445 , A61B8/4461 , A61B2090/3784 , A61M25/01 , A61M25/0105 , A61M25/0116 , G01S15/894
摘要： A device and a method for sealing a micromotor with an optional associated gearbox are disclosed where, in one aspect of the present invention, a catheter tip comprises: a micromotor; an ultrasound imaging transducer; a gearbox mechanically coupled to the micromotor, the gearbox having a rotatable portion mechanically coupled to the ultrasound imaging transducer array; and a moisture barrier disposed so as to reduce or prevent acoustic coupling fluid from entering both the gearbox and the micromotor.
摘要翻译：公开了一种用于与可选的相关联的齿轮箱密封微电机的装置和方法，其中在本发明的一个方面，导管尖端包括：微电机; 超声成像传感器; 机械地联接到所述微型马达的齿轮箱，所述齿轮箱具有机械耦合到所述超声波成像换能器阵列的可旋转部分; 以及设置为减少或防止声耦合流体进入齿轮箱和微型马达的防潮屏障。

13. 发明申请

US20100256502A1 MATERIALS AND PROCESSES FOR BONDING ACOUSTICALLY NEUTRAL STRUCTURES FOR USE IN ULTRASOUND CATHETERS 审中-公开
标题翻译：用于连接超声波导管中使用的中性结构的材料和方法
公开(公告)号：US20100256502A1
公开(公告)日：2010-10-07
申请号：US12418824
申请日：2009-04-06
申请人： Donald Joseph Buckley , Douglas Glenn Wildes , Warren Lee , Weston Blaine Griffin
发明人： Donald Joseph Buckley , Douglas Glenn Wildes , Warren Lee , Weston Blaine Griffin
IPC分类号： A61B8/14 , B29C45/14
CPC分类号： B32B37/24 , A61B8/12 , A61B8/4281 , A61B8/445 , B29C45/02 , B29C45/462 , B29L2031/7542 , G10K11/355
摘要： Provided herein is an ultrasound probe comprising a probe housing defining a distal end, an ultrasonic transducer array disposed within the probe housing and rotatable within said probe housing, an acoustically neutral structure bonded to a surface of the ultrasonic transducer array by an adhesive, a motor coupled to the ultrasonic transducer array, the motor being configured to rotate the ultrasonic transducer array in order to image a three-dimensional volume; and an acoustic coupling fluid disposed within free volume of the probe housing. Also provided is a method of manufacturing.
摘要翻译：本文提供了一种超声波探头，其包括限定远端的探针壳体，设置在探针壳体内并可在所述探针壳体内旋转的超声波换能器阵列，通过粘合剂结合到超声换能器阵列的表面的声中性结构，马达耦合到所述超声换能器阵列，所述马达被配置为旋转所述超声波换能器阵列，以便对三维体积进行成像; 以及设置在探针壳体的自由体积内的声耦合流体。还提供了一种制造方法。

14. 发明申请

US20100145310A1 Method and apparatus for Operating a Micromotor in a fluid 有权
标题翻译：在流体中操作微电机的方法和装置
公开(公告)号：US20100145310A1
公开(公告)日：2010-06-10
申请号：US12315747
申请日：2008-12-05
申请人： Warren Lee , Douglas Glenn Wildes , Weston Blaine Griffin
发明人： Warren Lee , Douglas Glenn Wildes , Weston Blaine Griffin
IPC分类号： A61M25/01 , A61B8/14
CPC分类号： A61M25/0082 , A61B8/12 , A61B8/445 , A61B8/4461 , A61B2090/3784 , A61M25/01 , A61M25/0105 , A61M25/0116 , G01S15/894
摘要： A device and a method for sealing a micromotor with an optional associated gearbox are disclosed where, in one aspect of the present invention, a catheter tip comprises: a micromotor; an ultrasound imaging transducer; a gearbox mechanically coupled to the micromotor, the gearbox having a rotatable portion mechanically coupled to the ultrasound imaging transducer array; and a moisture barrier disposed so as to reduce or prevent acoustic coupling fluid from entering both the gearbox and the micromotor.
摘要翻译：公开了一种用于与可选的相关联的齿轮箱密封微电机的装置和方法，其中在本发明的一个方面，导管尖端包括：微电机; 超声成像传感器; 机械地联接到所述微型马达的齿轮箱，所述齿轮箱具有机械耦合到所述超声波成像换能器阵列的可旋转部分; 以及设置为减少或防止声耦合流体进入齿轮箱和微型马达的防潮屏障。

15. 发明申请

US20080139893A1 Apparatus And System For Sensing and Analyzing Body Sounds 审中-公开
标题翻译：用于感应和分析身体声音的装置和系统
公开(公告)号：US20080139893A1
公开(公告)日：2008-06-12
申请号：US11608294
申请日：2006-12-08
申请人： Warren Lee , Weston Blaine Griffin , Mirsaid Seyed Bolorforosh , Kai Erik Thomenius
发明人： Warren Lee , Weston Blaine Griffin , Mirsaid Seyed Bolorforosh , Kai Erik Thomenius
IPC分类号： A61B5/00
CPC分类号： A61B7/04 , A61B2562/0204 , A61B2562/046
摘要： An apparatus and system for sensing body sounds of a subject is described. The apparatus includes a flexible sheet for conformally contacting at least a portion of a subject's body surface proximate a body region generating body sounds. The apparatus also includes a plurality of acoustic sensors formed in the sheet for sensing body sounds from the subject and generating respective signals indicative of the sensed body sounds.
摘要翻译：描述了用于感测被摄体的身体声音的装置和系统。该装置包括柔性片，用于在接近生物身体声音的身体区域之间保形接触被摄体的身体表面的至少一部分。该装置还包括形成在片材中的多个声学传感器，用于感测来自被摄体的身体声音，并产生指示感测到的身体声音的各个信号。

16. 发明授权

US07622848B2 Transducer assembly with z-axis interconnect 有权
标题翻译：具有z轴互连的传感器组件
公开(公告)号：US07622848B2
公开(公告)日：2009-11-24
申请号：US11327779
申请日：2006-01-06
申请人： Warren Lee , Charles Edward Baumgartner , Douglas Glenn Wildes , Robert Stephen Lewandowski
发明人： Warren Lee , Charles Edward Baumgartner , Douglas Glenn Wildes , Robert Stephen Lewandowski
IPC分类号： H01L41/08
CPC分类号： G10K11/002 , A61B8/12 , A61B8/445 , B06B1/0629 , G10K11/34
摘要： A composite structure of a z-axis interconnect is presented. The composite structure includes a plurality of layers of backing material alternatingly arranged between a plurality of interconnect layers, where the plurality of interconnect layers is configured to facilitate coupling the composite structure of the z-axis interconnect to a transducer array, where the composite structure of z-axis interconnect is configured for use in an invasive probe.
摘要翻译：介绍了z轴互连的复合结构。复合结构包括交替布置在多个互连层之间的多层背衬材料，其中多个互连层被配置为便于将z轴互连的复合结构耦合到换能器阵列，其中复合结构 z轴互连配置用于侵入性探针。

17. 发明授权

US07766833B2 Ablation array having independently activated ablation elements 有权
标题翻译：消融阵列具有独立激活的消融元件
公开(公告)号：US07766833B2
公开(公告)日：2010-08-03
申请号：US11276259
申请日：2006-02-21
申请人： Warren Lee , Mirsaid Seyed-Bolorforosh , Douglas Glenn Wildes
发明人： Warren Lee , Mirsaid Seyed-Bolorforosh , Douglas Glenn Wildes
IPC分类号： A61B8/00 , A61B8/14 , A61H1/00
CPC分类号： A61N7/022 , A61B8/06 , A61B8/12 , A61B8/4461 , A61B8/4488 , A61B8/483 , A61B8/485 , A61B2017/00243 , A61B2090/3782 , A61N2007/0078 , A61N2007/0082
摘要： A system for imaging and providing therapy to one or more regions of interest is presented. The system includes an imaging and therapy catheter configured to image an anatomical region to facilitate assessing need for therapy in one or more regions within the anatomical region and delivering therapy to the one or more regions of interest within the anatomical region. The catheter includes a therapy device having a plurality of independently controllable therapy elements. The independence of the therapy elements is exploited when multiple regions are to receive therapy simultaneously or at a given catheter position within a subject.
摘要翻译：提出了一种用于对一个或多个感兴趣区域进行成像和提供治疗的系统。该系统包括成像和治疗导管，其构造成对解剖区域进行成像，以便于评估在解剖区域内的一个或多个区域中的治疗需要，并将解决方案区域内的一个或多个感兴趣区域递送治疗。导管包括具有多个可独立控制的治疗元件的治疗装置。当多个区域同时接收治疗或在受试者内的给定导管位置时，治疗元件的独立性被利用。

18. 发明申请

US20110255249A1 HIGH DENSITY FLEXIBLE FOLDABLE INTERCONNECT 审中-公开
标题翻译：高密度柔性可折叠互连
公开(公告)号：US20110255249A1
公开(公告)日：2011-10-20
申请号：US12763391
申请日：2010-04-20
申请人： Warren Lee , Douglas Glenn Wildes , Svein Bergstoel
发明人： Warren Lee , Douglas Glenn Wildes , Svein Bergstoel
IPC分类号： H05K1/02
CPC分类号： H05K1/028 , A61B1/00114 , H05K1/0218 , H05K2201/055 , H05K2201/09063
摘要： A flexible interconnect circuit includes a plurality of substantially flat flex circuits. Each flex circuit has a length substantially greater than its corresponding width. The plurality of flex circuits are folded parallel to their long axes and configured together to provide a layered flex interconnect circuit structure in which at least one ground flex circuit is interposed with one or more signal flex circuits.
摘要翻译：柔性互连电路包括多个基本平坦的柔性电路。每个柔性电路的长度显着大于其对应的宽度。多个柔性电路平行于它们的长轴折叠并配置在一起以提供分层柔性互连电路结构，其中至少一个接地柔性电路插入有一个或多个信号柔性电路。

19. 发明申请

US20090076390A1 INTEGRATED ULTRASOUND IMAGING AND ABLATION PROBE 审中-公开
标题翻译：一体化超声成像和排除探针
公开(公告)号：US20090076390A1
公开(公告)日：2009-03-19
申请号：US12327171
申请日：2008-12-03
申请人： Warren Lee , Mirsaid Seyed-Bolorforosh , Douglas Glenn Wildes
发明人： Warren Lee , Mirsaid Seyed-Bolorforosh , Douglas Glenn Wildes
IPC分类号： A61B8/00 , A61N7/00
CPC分类号： A61N7/022 , A61B8/06 , A61B8/12 , A61B8/4461 , A61B8/4488 , A61B8/483 , A61B8/485 , A61B2017/00243 , A61B2090/3782 , A61N2007/0078 , A61N2007/0082
摘要： A system for imaging and providing therapy to one or more regions of interest is presented. The system includes an imaging and therapy catheter configured to image an anatomical region to facilitate assessing need for therapy in one or more regions within the anatomical region and delivering therapy to the one or more regions of interest within the anatomical region. In addition, the system includes a medical imaging system operationally coupled to the catheter and having a display area and a user interface area, wherein the medical imaging system is configured to facilitate defining a therapy pathway to facilitate delivering therapy to the one or more regions of interest.
摘要翻译：提出了一种用于对一个或多个感兴趣区域进行成像和提供治疗的系统。该系统包括成像和治疗导管，其构造成对解剖区域进行成像，以便于评估在解剖区域内的一个或多个区域中的治疗需要，并将解决方案区域内的一个或多个感兴趣区域递送治疗。此外，该系统包括可操作地耦合到导管并具有显示区域和用户界面区域的医学成像系统，其中医学成像系统被配置为有助于限定治疗路径，以促进将治疗递送到一个或多个区域利益。

20. 发明申请

US20100249598A1 ULTRASOUND PROBE WITH REPLACEABLE HEAD PORTION 审中-公开
标题翻译：超声波探头与可更换头部
公开(公告)号：US20100249598A1
公开(公告)日：2010-09-30
申请号：US12410525
申请日：2009-03-25
申请人： Lowell Scott Smith , Charles Edward Baumgartner , Charles Gerard Woychik , Warren Lee , Reinhold Bruestle , Ferdinand Puttinger
发明人： Lowell Scott Smith , Charles Edward Baumgartner , Charles Gerard Woychik , Warren Lee , Reinhold Bruestle , Ferdinand Puttinger
IPC分类号： A61B8/13 , H04R31/00
CPC分类号： B06B1/0622 , A61B8/00 , A61B8/0883 , A61B8/12 , A61B8/4411 , A61B8/4427 , A61B8/445 , A61B8/4455 , A61B8/483 , G01S7/52079 , G01S7/5208 , G01S7/52082 , Y10T29/49005
摘要： An ultrasound probe includes a transducer comprising an array of transducer elements removably disposed in a head portion. At least one or more stages of electronic circuit units is removably coupled to the transducer and configured to excite the transducer. A handle portion is detachably coupled to the head portion. The head portion and the handle portion are disposed enclosing the at least one or more stages of electronic circuit units. The ultrasound probe is used for one dimensional applications, two dimensional applications, and volumetric applications.
摘要翻译：超声波探头包括换能器，其包括可拆卸地设置在头部中的换能器元件阵列。电子电路单元的至少一个或多个级可移除地耦合到换能器并且被配置为激励换能器。手柄部分可拆卸地联接到头部。头部和把手部分被设置成包围至少一个或多个电子电路单元的阶段。超声波探头用于一维应用，二维应用和体积应用。

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