专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明授权

US5841914A Molecular detection apparatus and method using optical waveguide detection 失效
标题翻译：使用光波导检测的分子检测装置及方法
公开(公告)号：US5841914A
公开(公告)日：1998-11-24
申请号：US861927
申请日：1997-05-22
申请人： Chan-Long Shieh , Donald E. Ackley , George N. Maracas , Thomas B. Harvey, III
发明人： Chan-Long Shieh , Donald E. Ackley , George N. Maracas , Thomas B. Harvey, III
IPC分类号： G01N21/64 , G01N21/77 , G02B6/00 , G02B6/10 , G01N21/41
CPC分类号： G01N21/6454 , G01N21/7703 , G02B6/10
摘要： A target molecule at a binding site is detected using an optical waveguide having a surface proximate to the binding site, and a waveguide detector coupled to the optical waveguide. An incident light beam is applied to the binding site along an axis transverse to the surface of the optical waveguide. The incident light beam impinges an optical indicator associated with the target molecule to form secondary light which is coupled into the optical waveguide. The secondary light is detected by the waveguide detector to thereby detect the target molecule.
摘要翻译：使用具有接近结合位点的表面的光波导和耦合到光波导的波导检测器来检测结合位点处的靶分子。沿着横向于光波导表面的轴将入射光束施加到结合位点。入射光束照射与靶分子相关联的光学指示器，以形成耦合到光波导中的次级光。二次光被波导检测器检测，从而检测目标分子。

12. 发明申请

US20080167878A1 CONVERSATION OUTCOME ENHANCEMENT METHOD AND APPARATUS 有权
标题翻译：对话成果增强方法和设备
公开(公告)号：US20080167878A1
公开(公告)日：2008-07-10
申请号：US11620965
申请日：2007-01-08
申请人： Leonard C. Hause , Andrew J. Aftelak , George N. Maracas , James Kefeng Zhou , Robert A. Zurek
发明人： Leonard C. Hause , Andrew J. Aftelak , George N. Maracas , James Kefeng Zhou , Robert A. Zurek
IPC分类号： G10L11/00
CPC分类号： G10L15/22
摘要： A system [100] is provided that includes a first set of sensors [140] to sense a set of conditions of at least one participant in a conversation and generate raw data corresponding to the sensed set of conditions. A first aggregation engine [160] aggregates the raw data and outputs a file corresponding to the raw data. A heuristic engine [175] receives the file and compares the raw data with predetermined state data and outputs a state based on a comparison of the raw data and the predetermined state data. A feedback device [180] determines a corrective action to enhance an outcome of the conversation based on the state.
摘要翻译：提供了一种系统[100]，其包括第一传感器组140，用于感测对话中的至少一个参与者的一组条件，并且生成与感测的条件集相对应的原始数据。第一聚合引擎[160]聚合原始数据并输出与原始数据相对应的文件。启发式引擎[175]接收文件并将原始数据与预定状态数据进行比较，并且基于原始数据和预定状态数据的比较来输出状态。反馈装置[180]基于状态确定校正动作以增强对话的结果。

13. 发明申请

US20080140421A1 Speaker Tracking-Based Automated Action Method and Apparatus 审中-公开
标题翻译：基于扬声器跟踪的自动动作方法和装置
公开(公告)号：US20080140421A1
公开(公告)日：2008-06-12
申请号：US11567859
申请日：2006-12-07
申请人： Lawrence J. Marturano , Scott B. Davis , Robert A. Zurek , Andrew J. Aftelak , George N. Maracas
发明人： Lawrence J. Marturano , Scott B. Davis , Robert A. Zurek , Andrew J. Aftelak , George N. Maracas
IPC分类号： G10L21/00
CPC分类号： G10L17/00
摘要： At least some speakers engaged in an oral discourse are identified (101) and their oral contributions during that oral discourse tracked (102). At least one visual indicator provided (103) during the oral discourse serves to provide data regarding these tracked contributions (such as, but not limited to, an aggregate length of time that one or more of the participants has spoken). These teachings also provide, however, for automatically taking (104) at least one other action, during the oral discourse, as a function, at least in part, of this tracked oral contribution information.
摘要翻译：至少有一些在口头话语中发言的人被发现（101），并且在口头话语跟踪（102）期间他们的口头贡献。在口头话语期间提供的至少一个视觉指示（103）用于提供关于这些跟踪的贡献的数据（例如但不限于一个或多个参与者所说的总时间长度）。然而，这些教导还提供了在口头话语期间至少部分地作为该跟踪口头贡献信息的功能自动采取（104）至少一个其他动作。

14. 发明授权

US6060023A Molecular sensing apparatus 失效
标题翻译：分子感测装置
公开(公告)号：US6060023A
公开(公告)日：2000-05-09
申请号：US52559
申请日：1998-03-31
申请人： George N. Maracas
发明人： George N. Maracas
IPC分类号： G01N33/50 , A61K38/00 , C12M1/00 , C40B40/06 , G01N1/14 , G01N15/06 , G01N25/18 , G01N27/00 , G01N27/12 , G01N27/327 , G01N33/53 , G01N37/00
CPC分类号： G01N27/3276 , B01J2219/00605 , B01J2219/00626 , B01J2219/00637 , B01J2219/00653 , B01J2219/00722 , C40B40/06 , Y10S436/806 , Y10S436/807
摘要： A molecular sensing apparatus comprises a first electrode (10), a second electrode (12), a first molecule (20), a second molecule (22), and a third molecule (34). The first molecule (20) has a first chain of nucleic bases (30) and a first group (24). The first group (24) is bound to the first electrode (10). The second molecule (22) has a second chain of nucleic bases (32) and a second group (26). The second group (26) is bound to the second electrode (12). The third molecule (34) is bound to the first molecule (20) and the second molecule (22). A method which uses the molecular sensing apparatus is disclosed.
摘要翻译：分子感测装置包括第一电极（10），第二电极（12），第一分子（20），第二分子（22）和第三分子（34）。第一分子（20）具有第一核酸基（30）和第一组（24）。第一组（24）与第一电极（10）结合。第二分子（22）具有第二链核酸基（32）和第二组（26）。第二组（26）与第二电极（12）结合。第三分子（34）与第一分子（20）和第二分子（22）结合。公开了一种使用分子感测装置的方法。

15. 发明授权

US5671303A Molecular detection apparatus and method using optical waveguide detection 失效
标题翻译：使用光波导检测的分子检测装置及方法
公开(公告)号：US5671303A
公开(公告)日：1997-09-23
申请号：US634103
申请日：1996-04-17
申请人： Chan-Long Shieh , Donald E. Ackley , George N. Maracas , Thomas B. Harvey, III
发明人： Chan-Long Shieh , Donald E. Ackley , George N. Maracas , Thomas B. Harvey, III
IPC分类号： G01N21/64 , G01N21/77 , G02B6/00 , G02B6/10 , G01N21/41
CPC分类号： G01N21/6454 , G01N21/7703 , G02B6/10
摘要： A target molecule at a binding site is detected using an optical waveguide having a surface proximate to the binding site, and a waveguide detector coupled to the optical waveguide. An incident light beam is applied to the binding site along an axis transverse to the surface of the optical waveguide. The incident light beam impinges an optical indicator associated with the target molecule to form secondary light which is coupled into the optical waveguide. The secondary light is detected by the waveguide detector to thereby detect the target molecule.
摘要翻译：使用具有接近结合位点的表面的光波导和耦合到光波导的波导检测器来检测结合位点处的靶分子。沿着横向于光波导表面的轴将入射光束施加到结合位点。入射光束照射与靶分子相关联的光学指示器，以形成耦合到光波导中的次级光。二次光被波导检测器检测，从而检测目标分子。

16. 发明授权

US5669303A Apparatus and method for stamping a surface 失效
标题翻译：用于冲压表面的装置和方法
公开(公告)号：US5669303A
公开(公告)日：1997-09-23
申请号：US610776
申请日：1996-03-04
申请人： George N. Maracas , Lawrence N. Dworsky , Kathleen Tobin
发明人： George N. Maracas , Lawrence N. Dworsky , Kathleen Tobin
IPC分类号： B41K3/02 , B05C1/02 , B05D1/18 , B05D1/28 , C40B60/14 , G03F7/00 , H01L21/027 , B41F31/00
CPC分类号： B82Y30/00 , B05C1/027 , B05D1/185 , B05D1/28 , B05D1/283 , B82Y10/00 , B82Y40/00 , G03F7/0002 , B01J2219/00382 , C40B60/14
摘要： An apparatus (100) including a support structure (104), a flexible stamp (106) having a stamping surface (110) including a predetermined pattern disposed opposite the support structure (104), a pressure controlled chamber (112) disposed above the support structure (104), and a mechanical attachment (114) affixed to the flexible stamp (106). A method is provided for stamping the surface (101) of an article (102) including the steps of i) placing the article (102) on the support structure (104) within the pressure-controlled chamber (112), ii) wetting the stamping surface (110) with a solution containing a self-assembled monolayer-forming molecular species, iii) aligning alignment patterns (118) on the flexible stamp (106) with alignment patterns (124) on the surface (101) of the article (102), iv) controllably contacting the wetted stamping surface (110) with the surface (101) of the article (102) by changing the pressure differential across the flexible stamp (106) so that contact commences at the center of the flexible stamp (106) and proceeds outwardly in a controlled manner, and v) removing the stamping surface (110) from the surface (101) of the article so that a self-assembled monolayer (134) having the predetermined pattern is formed on the surface (101) of the article (102).
摘要翻译：一种包括支撑结构（104）的装置（100），具有包括与所述支撑结构（104）相对设置的预定图案的冲压表面的柔性印模（106），设置在所述支撑结构（104）上方的压力控制室结构（104）和固定到柔性印模（106）上的机械附件（114）。提供了一种用于冲压制品（102）的表面（101）的方法，包括以下步骤：i）将制品（102）放置在压力控制室（112）内的支撑结构（104）上，ii）润湿用包含自组装单层形成分子种类的溶液冲压表面（110），iii）将柔性印模（106）上的对准图案（118）与制品的表面（101）上的对准图案（124）对准（ 102），iv）通过改变柔性印章（106）上的压差来可控地将湿润的冲压表面（110）与制品（102）的表面（101）接触，使得在柔性印模的中心开始接触 106），并且以受控的方式向外移动，以及v）从制品的表面（101）移除冲压表面（110），使得在表面（101）上形成具有预定图案的自组装单层（134））的物品（102）。

17. 发明授权

US5073230A Means and methods of lifting and relocating an epitaxial device layer 失效
标题翻译：提升和重新定位外延器件层的方法和方法
公开(公告)号：US5073230A
公开(公告)日：1991-12-17
申请号：US510276
申请日：1990-04-17
申请人： George N. Maracas , Ronald A. Ruechner , Donald S. Gerber
发明人： George N. Maracas , Ronald A. Ruechner , Donald S. Gerber
IPC分类号： H01L21/20
CPC分类号： H01L21/02546 , H01L21/6835 , H01L21/7813 , H01L2221/6835 , H01L2221/68368 , H01L2221/68381 , Y10S117/915
摘要： Means and methods for obtaining the separation of large area semiconductorpitaxial device layers from the substrates on which they are grown, the transfer of the grown epi layers to a new host substrate for mounted alignment with features of the new host, and reuse of the original substrate.
摘要翻译：用于获得大面积半导体外延器件层从其生长的衬底上分离的方法和方法，将生长的epi层转移到新的主体衬底以与新主体的特征进行安装对准，以及重新使用原始基质。

18. 发明授权

US07894511B2 Multi-device coordinated audio playback 有权
标题翻译：多设备协调音频播放
公开(公告)号：US07894511B2
公开(公告)日：2011-02-22
申请号：US11459064
申请日：2006-07-21
申请人： Robert A. Zurek , Andrew J. Aftelak , George N. Maracas
发明人： Robert A. Zurek , Andrew J. Aftelak , George N. Maracas
IPC分类号： H04L5/16
CPC分类号： H04L29/06027 , H04L65/4076 , H04L65/4092 , H04L65/604 , H04L65/607
摘要： A wireless device (100) provides coordinated audio playback. The device (100) includes a network interface (112) that receives a signal from a sending or originating device (401) and sends a reply to the signal. A network delay value is then calculated based on the reply to the signal. The wireless device (100) then receives a location of the originating device (401) and at least a portion of an audio file. The wireless device (100) generates audio from the audio file, with the generation being coordinated with audio generation by the originating device (401) based upon the network delay value and the distance between the wireless device (100) and the originating device (401).
摘要翻译：无线设备（100）提供协调的音频回放。设备（100）包括从发送或发起设备（401）接收信号并向该信号发送回复的网络接口（112）。然后基于对信号的回复来计算网络延迟值。无线设备（100）然后接收始发设备（401）的位置和音频文件的至少一部分。无线设备（100）根据网络延迟值和无线设备（100）与始发设备（401）之间的距离，从音频文件生成音频，其中生成与发起设备（401）的音频生成协调，）。

19. 发明授权

US07613488B1 Apparatus and methods for compensation of blood volume effects on NIR spectroscopic measurements of blood analytes 有权
标题翻译：血液分析物对近红外光谱测量血容量影响的装置和方法
公开(公告)号：US07613488B1
公开(公告)日：2009-11-03
申请号：US10745234
申请日：2003-12-22
申请人： George N. Maracas , Romuald Pawluczyk , Duncan MacIntyre , Bronislaw Bednarz , Darin L. Farrelly , Chris Sterne , Ash Kaushal , Mang Li , Kenneth Anthony Morand
发明人： George N. Maracas , Romuald Pawluczyk , Duncan MacIntyre , Bronislaw Bednarz , Darin L. Farrelly , Chris Sterne , Ash Kaushal , Mang Li , Kenneth Anthony Morand
IPC分类号： A61B5/1455
CPC分类号： A61B5/14546 , A61B5/0053 , A61B5/0055 , A61B5/14532 , A61B2560/0252
摘要： The present invention provides a method for measuring a blood analyte concentration of a body part comprising removing a portion or all of the blood from the body part to produce a modified body part, and recording a first absorbance value of the modified body part. This is followed by filling the body part with blood to produce a filled body part, and recording a second absorbance value of the filled body part. A difference spectrum is obtained by subtracting the first absorbance values from the second absorbance values, and a calibration algorithm for the blood analyte is applied to the difference spectrum, thereby measuring the concentration of the blood analyte. Also provided is an apparatus for determining the concentration of a blood analyte of a body part. The apparatus comprising a chamber of a size and shape to receive the body part, where the chamber comprises an element for withdrawing and reintroducing blood from the body part, when the body part is inserted within the chamber. The chamber also comprising one or more than one port for introducing electromagnetic radiation into the chamber and onto that body part, and collecting remaining electromagnetic radiation following interaction with the body part.
摘要翻译：本发明提供一种用于测量身体部位的血液分析物浓度的方法，包括从身体部位除去一部分或全部血液以产生修饰体部，并记录修饰体部的第一吸光度值。随后用血液填充身体部分以产生填充体部分，并记录填充体部分的第二吸光度值。通过从第二吸光度值减去第一吸光度值获得差分光谱，并且将血液分析物的校准算法应用于差分光谱，从而测量血液分析物的浓度。还提供了一种用于确定身体部位的血液分析物的浓度的装置。所述装置包括容纳身体部分的尺寸和形状的腔室，其中当所述身体部分插入所述腔室内时，所述腔室包括用于从所述身体部分抽出并再次引入血液的元件。所述腔室还包括一个或多于一个端口，用于将电磁辐射引入所述腔室并且到达所述身体部分，并且在与身体部位相互作用之后收集剩余的电磁辐射。

20. 发明申请

US20080179191A1 TWO-STEP MOLECULAR SURFACE IMPRINTING METHOD FOR MAKING A SENSOR 审中-公开
标题翻译：用于制造传感器的两步分子表面印刷方法
公开(公告)号：US20080179191A1
公开(公告)日：2008-07-31
申请号：US11668639
申请日：2007-01-30
申请人： Yanxiu Zhou , George N. Maracas
发明人： Yanxiu Zhou , George N. Maracas
IPC分类号： C25D5/00 , B05D3/10
CPC分类号： G01N27/4035 , G01N27/333
摘要： A method is provided for detecting target molecules (60) using a surface-molecularly imprinted sensor (52) and more particularly for detecting hydroxyl containing molecules, heavy metal ions, or thiol- or dialkylamine containing molecules by integrating molecular recognition and sensor transduction. The method includes soaking a support surface (14) in a solution containing a ligand molecule with headgroups that could adsorb on the surface of a substrate, or monomer to create a monolayer, a monolayer of polymerized organosiloxane groups (16), or a conducting film on the support surface (14). Template molecules (18) are then added to the imprinting solution so as to be positioned within the sparsely formed film, wherein the template molecules (18) comprise hydroxyl containing molecules, heavy metal ions, or thiol and dialkylamine containing molecules which prevents the interaction between monomer/ligand molecules and template molecules (18). In this case, there is a competitive reaction between the hydroxyl group on the surface of substrate and hydroxyl in ethanol molecule with monomer, e.g. OTS. The template molecules (18) are removed to define cavities in the imprinted film (16).
摘要翻译：提供一种使用表面分子印迹传感器（52）检测目标分子（60）的方法，更具体地，通过整合分子识别和传感器转导来检测含羟基的分子，重金属离子或含巯基或二烷基胺的分子。该方法包括将支撑表面（14）浸泡在含有配体分子的溶液中，所述溶液具有可吸附在基材表面上的头基，或单体以形成单层，单层聚合的有机硅氧烷基团（16）或导电膜在支撑表面（14）上。然后将模板分子（18）加入到印迹溶液中以便定位在稀疏形成的膜中，其中模板分子（18）包含含羟基的分子，重金属离子或含硫醇和二烷基胺的分子，其阻止了单体/配体分子和模板分子（18）。在这种情况下，底物表面的羟基与乙醇分子中的羟基与单体之间存在竞争性反应，例如。 OTS。去除模板分子（18）以限定印刷膜（16）中的空腔。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式