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11. 发明申请

US20120296348A1 APPARATUS FOR MANIPULATING AND SECURING TISSUE 有权
标题翻译：用于操作和安全组织的装置
公开(公告)号：US20120296348A1
公开(公告)日：2012-11-22
申请号：US13491273
申请日：2012-06-07
申请人： Vahid Saadat , Richard C. Ewers , Cang C. Laduca , Robert A. Vaughan , Chris Rothe , Kenneth J. Michlitsch
发明人： Vahid Saadat , Richard C. Ewers , Cang C. Laduca , Robert A. Vaughan , Chris Rothe , Kenneth J. Michlitsch
IPC分类号： A61B17/04
CPC分类号： A61F5/0086 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0483 , A61B17/0487 , A61B17/06 , A61B17/06066 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/12013 , A61B17/1285 , A61B17/29 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488
摘要： Apparatus for manipulating and securing tissue are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably dispose through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. The stabilizing members can be adapted to become angled relative to longitudinal axis of the elongate tubular member. Moreover, one or all the articulation controls and functions can be integrated into a singular handle assembly connectable to the tissue manipulation assembly via a rigid or flexible tubular body.
摘要翻译：本文描述了用于操纵和固定组织的装置。在组织折叠在患者身体内部时，组织操作组件通常可以具有细长的管状构件，可滑动地配置穿过管状构件的接合构件和适于经由螺旋构件接合组织的远端，组织稳定构件所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。稳定构件可以适于相对于细长管状构件的纵向轴线成角度。此外，一个或所有关节运动控制和功能可以集成到通过刚性或柔性管状体连接到组织操作组件的单个手柄组件中。

12. 发明授权

US09510817B2 Apparatus for manipulating and securing tissue 有权
标题翻译：用于操纵和固定组织的装置
公开(公告)号：US09510817B2
公开(公告)日：2016-12-06
申请号：US13491273
申请日：2012-06-07
申请人： Vahid Saadat , Richard C. Ewers , Cang C. Laduca , Robert A. Vaughan , Chris Rothe , Kenneth J. Michlitsch
发明人： Vahid Saadat , Richard C. Ewers , Cang C. Laduca , Robert A. Vaughan , Chris Rothe , Kenneth J. Michlitsch
IPC分类号： A61B17/04 , A61B17/08 , A61B17/10 , A61B17/06 , A61B17/064 , A61B17/29 , A61B17/00 , A61B17/34
CPC分类号： A61F5/0086 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0483 , A61B17/0487 , A61B17/06 , A61B17/06066 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/12013 , A61B17/1285 , A61B17/29 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488
摘要： Apparatus for manipulating and securing tissue are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably dispose through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. The stabilizing members can be adapted to become angled relative to longitudinal axis of the elongate tubular member. Moreover, one or all the articulation controls and functions can be integrated into a singular handle assembly connectable to the tissue manipulation assembly via a rigid or flexible tubular body.
摘要翻译：本文描述了用于操纵和固定组织的装置。在组织折叠在患者身体内部时，组织操作组件通常可以具有细长的管状构件，可滑动地配置穿过管状构件的接合构件和适于经由螺旋构件接合组织的远端，组织稳定构件所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。稳定构件可以适于相对于细长管状构件的纵向轴线成角度。此外，一个或所有关节运动控制和功能可以集成到通过刚性或柔性管状体连接到组织操作组件的单个手柄组件中。

13. 发明授权

US08926634B2 Apparatus and methods for manipulating and securing tissue 有权
标题翻译：用于操纵和固定组织的装置和方法
公开(公告)号：US08926634B2
公开(公告)日：2015-01-06
申请号：US11951188
申请日：2007-12-05
申请人： Chris A. Rothe , Richard C. Ewers , Cang C. Lam , Vahid Saadat , Kenneth J. Michlitsch
发明人： Chris A. Rothe , Richard C. Ewers , Cang C. Lam , Vahid Saadat , Kenneth J. Michlitsch
IPC分类号： A61B17/00 , A61B17/10 , A61B17/08 , A61B1/00 , A61B17/06 , A61B17/295 , A61B19/00 , A61B17/04 , A61B17/34 , A61B17/29
CPC分类号： A61B1/0014 , A61B17/0401 , A61B17/06066 , A61B17/29 , A61B17/295 , A61B2017/00867 , A61B2017/00876 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0496 , A61B2017/06052 , A61B2017/06076 , A61B2017/3488 , A61B2090/037
摘要： Apparatus and methods for manipulating and securing tissue are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. The stabilizing members can be adapted to become angled relative to a longitudinal axis of the elongate tubular member. Moreover, one or all the articulation controls and functions can be integrated into a singular handle assembly connectable to the tissue manipulation assembly via a rigid or flexible tubular body.
摘要翻译：本文描述了用于操纵和固定组织的装置和方法。在组织折叠在患者体内产生时，组织操作组件通常可以具有细长的管状构件，可滑动地设置穿过管状构件的接合构件和适于通过螺旋构件接合组织的远端，位于所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。稳定构件可以适于相对于细长管状构件的纵向轴线成角度。此外，一个或所有关节运动控制和功能可以集成到通过刚性或柔性管状体连接到组织操作组件的单个手柄组件中。

14. 发明授权

US08343175B2 Apparatus and methods for forming and securing gastrointestinal tissue folds 有权
公开(公告)号：US08343175B2
公开(公告)日：2013-01-01
申请号：US12767731
申请日：2010-04-26
申请人： Richard C. Ewers , Vahid Saadat , Kenneth J. Michlitsch , Chris A. Rothe , Rodney C. Brenneman , Cang C. Lam , Eugene G. Chen
发明人： Richard C. Ewers , Vahid Saadat , Kenneth J. Michlitsch , Chris A. Rothe , Rodney C. Brenneman , Cang C. Lam , Eugene G. Chen
IPC分类号： A61B17/08
CPC分类号： A61B1/0055 , A61B1/00135 , A61B1/018 , A61B1/2736 , A61B1/31 , A61B17/00234 , A61B17/0218 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0487 , A61B17/062 , A61B17/0625 , A61B17/0644 , A61B17/29 , A61B17/295 , A61B17/3421 , A61B17/3468 , A61B17/3478 , A61B2017/00269 , A61B2017/003 , A61B2017/00353 , A61B2017/00827 , A61B2017/0404 , A61B2017/0417 , A61B2017/0419 , A61B2017/0443 , A61B2017/0451 , A61B2017/0454 , A61B2017/0458 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/061 , A61B2017/06176 , A61B2017/0649 , A61B2017/2905 , A61B2017/2927 , A61B2017/2943 , A61B2017/3445 , A61B2017/3488 , A61B2090/3614 , A61F5/0086
摘要： Apparatus and methods are provided for forming a gastrointestinal tissue fold by engaging tissue at a first tissue contact point and moving the first tissue contact point from a position initially distal to, or in line with, a second tissue contact point to a position proximal of the second contact point, thereby forming the tissue fold, and extending an anchor assembly through the tissue fold from a vicinity of the second tissue contact point. Adjustable anchor assemblies; as well as anchor delivery systems, shape-lockable guides and methods for endoluminally performing medical procedures, such as gastric reduction, treatment of gastroesophageal reflux disease, resection of lesions, and treatment of bleeding sites; are also provided.

15. 发明授权

US07361180B2 Apparatus for manipulating and securing tissue 有权
标题翻译：用于操纵和固定组织的装置
公开(公告)号：US07361180B2
公开(公告)日：2008-04-22
申请号：US10954666
申请日：2004-09-29
申请人： Vahid Saadat , Richard C. Ewers , Cang C. Lam , Robert A. Vaughan , Chris Rothe , Kenneth J. Michlitsch
发明人： Vahid Saadat , Richard C. Ewers , Cang C. Lam , Robert A. Vaughan , Chris Rothe , Kenneth J. Michlitsch
IPC分类号： A61B17/00 , A61B17/10 , A61B17/08
CPC分类号： A61F5/0086 , A61B17/0401 , A61B17/0469 , A61B17/0482 , A61B17/0483 , A61B17/0487 , A61B17/06 , A61B17/06066 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/12013 , A61B17/1285 , A61B17/29 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488
摘要： Apparatus for manipulating and securing tissue are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. The stabilizing members can be adapted to become angled relative to a longitudinal axis of the elongate tubular member. Moreover, one or all the articulation controls and functions can be integrated into a singular handle assembly connectable to the tissue manipulation assembly via a rigid or flexible tubular body.
摘要翻译：本文描述了用于操纵和固定组织的装置。在组织折叠在患者体内产生时，组织操作组件通常可以具有细长的管状构件，可滑动地设置穿过管状构件的接合构件和适于通过螺旋构件接合组织的远端，组织稳定构件所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。稳定构件可以适于相对于细长管状构件的纵向轴线成角度。此外，一个或所有关节运动控制和功能可以集成到通过刚性或柔性管状体连接到组织操作组件的单个手柄组件中。

16. 发明申请

US20110190772A1 POWERED TISSUE MODIFICATION DEVICES AND METHODS 审中-公开
标题翻译：动力组织修改装置和方法
公开(公告)号：US20110190772A1
公开(公告)日：2011-08-04
申请号：US13078376
申请日：2011-04-01
申请人： Vahid Saadat , Jeffery L. Bleich , Kenneth J. Michlitsch , John E. Ashley
发明人： Vahid Saadat , Jeffery L. Bleich , Kenneth J. Michlitsch , John E. Ashley
IPC分类号： A61B17/56
CPC分类号： A61B17/1659 , A61B17/1671
摘要： A device for modifying tissue in a spine may include: a shah having a proximal portion and a distal portion, the distal portion having dimensions which allow h to be passed into an epidural space of the spine and between target and non-target tissues at least one distal force application member extending from the distal portion of the shall and configured to facilitate application of at least one of anchoring force and tensioning force to the shaft; at least one movable tissue modifying member coupled with the shaft at or near its distal portion; at least one drive member coupled with the at least one tissue modifying member to activate the at least one tissue modifying member; and at least one power transmission member coupled with the at least one drive member to deliver power to the at least one drive member.
摘要翻译：用于修改脊柱中的组织的装置可以包括：具有近端部分和远端部分的髋部，所述远端部分具有允许h至少进入脊柱的硬膜外腔和靶和非靶组织之间的尺寸从远端部分延伸的一个远端力施加构件应构造成便于将锚固力和张紧力中的至少一个施加到轴上; 至少一个可动组织修改构件，其在远端部分处或其附近与所述轴联接; 至少一个驱动构件与所述至少一个组织修改构件联接以激活所述至少一个组织修改构件; 以及与所述至少一个驱动构件联接的至少一个动力传递构件，以向所述至少一个驱动构件输送动力。

17. 发明授权

US08216252B2 Tissue manipulation and securement system 有权
标题翻译：组织操纵和固定系统
公开(公告)号：US08216252B2
公开(公告)日：2012-07-10
申请号：US11070863
申请日：2005-03-01
申请人： Robert A. Vaughan , Cang C. Lam , Richard C. Ewers , Vahid Saadat
发明人： Robert A. Vaughan , Cang C. Lam , Richard C. Ewers , Vahid Saadat
IPC分类号： A61B17/08
CPC分类号： A61B17/0401 , A61B17/0487 , A61B17/06066 , A61B17/29 , A61B2017/00278 , A61B2017/0409 , A61B2017/0419 , A61B2017/0464 , A61B2017/0496 , A61B2017/06052 , A61B2017/06076 , A61B2017/2923 , A61B2017/2927 , A61B2017/3488
摘要： Tissue manipulation and securement systems are described herein. A tissue manipulation assembly is pivotably coupled to the distal end of a tubular member and has a lower jaw member and an upper jaw member pivotably coupled to the lower jaw member. A reconfigurable launch tube is also pivotably coupled to the upper jaw member and is used to urge the jaw members from a low-profile configuration to an open configuration for receiving tissue. The tissue manipulation assembly may be advanced through a shape-lockable endoscopic device, a conventional endoscope, or directly by itself into a patient. A second tool can be used in combination with the tissue manipulation assembly to engage tissue and manipulate the tissue in conjunction with the tissue manipulation assembly.
摘要翻译：本文描述了组织操纵和固定系统。组织操作组件可枢转地联接到管状构件的远端，并且具有下颚构件和可枢转地联接到下颚构件的上颚构件。可重构的发射管也可枢转地联接到上钳口构件，并且用于将钳口构件从小轮廓构造推动到用于接收组织的打开构型。组织操作组件可以通过形状可锁定内窥镜装置，常规内窥镜，或者直接自身进入患者。第二工具可以与组织操作组件组合使用以接合组织并且与组织操作组件一起操作组织。

18. 发明申请

US20100042115A1 NEEDLE ASSEMBLY FOR TISSUE MANIPULATION 有权
标题翻译：用于组织操作的针组件
公开(公告)号：US20100042115A1
公开(公告)日：2010-02-18
申请号：US12579295
申请日：2009-10-14
申请人： Vahid Saadat , Chris Rothe , Richard C. Ewers
发明人： Vahid Saadat , Chris Rothe , Richard C. Ewers
IPC分类号： A61B17/10
CPC分类号： A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/06066 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/29 , A61B2017/00349 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488
摘要： Needle assemblies for tissue manipulation are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably disposed through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. A needle deployment assembly is deployable through the tissue manipulation assembly via a handle assembly, through the tubular member, and into or through tissue. An elongate pusher is translationally disposed within a sheath of the needle deployment assembly and can be urged distally for deploying an anchor assembly from the sheath distal end. The anchor assembly is positioned distally of the pusher within the sheath.
摘要翻译：用于组织操作的针组件在本文中描述。在组织折叠在患者体内产生时，组织操作组件通常可以具有细长的管状构件，可滑动地设置穿过管状构件的接合构件和适于通过螺旋构件接合组织的远端，组织稳定构件所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。针部署组件可经由手柄组件穿过组织操纵组件展开，穿过管状构件，并且进入或穿过组织。细长的推动器平移地设置在针展开组件的护套内，并且可以向远侧推动以从护套远端展开锚固组件。锚固组件位于鞘内的推动器的远侧。

19. 发明授权

US06960162B2 Shape lockable apparatus and method for advancing an instrument through unsupported anatomy 有权
标题翻译：形状可锁定装置和方法，用于通过不支持的解剖结构推进器械
公开(公告)号：US06960162B2
公开(公告)日：2005-11-01
申请号：US10281426
申请日：2002-10-25
申请人： Vahid Saadat , Richard C. Ewers
发明人： Vahid Saadat , Richard C. Ewers
IPC分类号： A61B1/005 , A61B1/008 , A61B1/01 , A61B1/31 , A61B1/32 , A61B1/00
CPC分类号： A61B1/00154 , A61B1/00078 , A61B1/0008 , A61B1/00082 , A61B1/00105 , A61B1/00135 , A61B1/0052 , A61B1/0055 , A61B1/0058 , A61B1/008 , A61B1/31 , A61B1/32
摘要： Apparatus and methods are provided for placing and advancing a diagnostic or therapeutic instrument in a hollow body organ of a tortuous or unsupported anatomy, comprising a handle, an overtube disposed within a hydrophilic sheath, and a distal region having an atraumatic tip. The overtube may be removable from the handle, and have a longitudinal axis disposed at an angle relative to the handle. The sheath may be disposable to permit reuse of the overtube. Fail-safe tensioning mechanisms may be provided to selectively stiffen the overtube to reduce distension of the organ caused by advancement of the diagnostic or therapeutic instrument. The fail-safe tensioning mechanisms reduce the risk of reconfiguration of the overtube in the event that the tension system fails, and, in one embodiment, rigidizes the overtube without substantial proximal movement of the distal region. The distal region permits passive steering of the overtube caused by deflection of the diagnostic or therapeutic instrument, while the atraumatic tip prevents the wall of the organ from becoming caught or pinched during manipulation of the diagnostic or therapeutic instrument.
摘要翻译：提供了设备和方法，用于将诊断或治疗仪器放置在曲折或无支撑的解剖结构的空心体器官中，包括手柄，设置在亲水护套内的外套管，以及具有无创尖端的远侧区域。外套管可以从手柄移除，并且具有相对于把手以一定角度设置的纵向轴线。护套可以是一次性的，以允许外套管的再次使用。可以提供故障安全的张紧机构以选择性地加固外套管，以减少由诊断或治疗仪器的前进引起的器官的膨胀。在张力系统失效的情况下，故障安全张紧机构降低了外套管的重新配置的风险，并且在一个实施例中，使外套管刚性化，而远端区域没有实质的近端运动。远侧区域允许由诊断或治疗仪器的偏转引起的外套管的被动转向，而无创伤尖端防止器官的壁在操纵诊断或治疗仪器期间被卡住或夹住。

20. 发明申请

US20050277981A1 Apparatus and methods for optimizing anchoring force 有权
标题翻译：用于优化锚固力的装置和方法
公开(公告)号：US20050277981A1
公开(公告)日：2005-12-15
申请号：US10865243
申请日：2004-06-09
申请人： Tracy Maahs , Richard Ewers , Vahid Saadat , Alex Khairkhahan , Kenneth Michlitsch
发明人： Tracy Maahs , Richard Ewers , Vahid Saadat , Alex Khairkhahan , Kenneth Michlitsch
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/08 , A61B19/00
CPC分类号： A61B17/0482 , A61B17/0401 , A61B17/0469 , A61B17/0644 , A61B2017/00867 , A61B2017/0454 , A61B2017/0464 , A61B2017/0496 , A61B2017/06052 , A61B2090/037
摘要： Apparatus and methods for optimizing anchoring force are described herein. In securing tissue folds, over-compression of the tissue directly underlying the anchors is avoided by utilizing tissue anchors having expandable arms configured to minimize contact area between the anchor and tissue. When the anchor is in its expanded configuration, a load is applied to the anchor until it is optimally configured to accommodate a range of deflections while the anchor itself exerts a substantially constant force against the tissue. Various devices, e.g., stops, spring members, fuses, strain gauges, etc., can be used to indicate when the anchor has been deflected to a predetermined level within the optimal range. Moreover, other factors to affect the anchor characteristics include, e.g., varying the number of arms or struts of the anchor, positioning of the arms, configuration of the arms, the length of the collars, etc.
摘要翻译：本文描述了用于优化锚固力的装置和方法。在固定组织褶皱时，通过利用具有可扩张臂的组织锚来避免直接位于锚固件正下方的组织的过度压缩，所述组织锚构造成使锚和组织之间的接触面积最小化。当锚固件处于其膨胀构型时，将负载施加到锚固件，直到其被最佳地构造成适应一定范围的偏转，同时锚固件本身对组织施加基本恒定的力。可以使用各种装置，例如止动件，弹簧构件，保险丝，应变计等来指示锚固件何时被偏转到最佳范围内的预定水平。此外，影响锚固特征的其他因素包括例如改变锚的臂或支柱的数量，臂的定位，臂的构型，套环的长度等。

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