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11. 发明授权

US08298179B2 Catheter assembly with tapered joints and method of manufacture 有权
标题翻译：具有锥形接头的导管组件和制造方法
公开(公告)号：US08298179B2
公开(公告)日：2012-10-30
申请号：US11020540
申请日：2004-12-22
申请人： Thomas J. Holman , Afsar Ali
发明人： Thomas J. Holman , Afsar Ali
IPC分类号： A61M25/10
CPC分类号： A61M25/1034 , A61M25/10 , A61M2025/1093 , Y10T156/10
摘要： A catheter assembly comprises at least one catheter shaft and a balloon. The catheter shaft comprises a substantially cylindrical portion and at least one tapered portion. The tapered portion forms an angle with the cylindrical portion of about 1 degree to about 25 degrees. At least one of the waists of the balloon is sealingly engaged to the tapered portion.
摘要翻译：导管组件包括至少一个导管轴和气囊。导管轴包括基本上圆柱形的部分和至少一个锥形部分。锥形部分与圆柱形部分形成约1度至约25度的角度。球囊的至少一个腰部密封地接合到锥形部分。

12. 发明授权

US07419563B2 Methods of making medical devices 有权
标题翻译：制造医疗器械的方法
公开(公告)号：US07419563B2
公开(公告)日：2008-09-02
申请号：US11166027
申请日：2005-06-23
申请人： Thomas J. Holman , Afsar Ali , Stacie Depner
发明人： Thomas J. Holman , Afsar Ali , Stacie Depner
IPC分类号： B32B37/00
CPC分类号： B29C65/04 , A61M25/005 , A61M25/1036 , A61M25/104 , A61M2025/1031 , A61M2025/1056 , B29C65/14 , B29C65/1406 , B29C65/1409 , B29C65/1412 , B29C65/1496 , B29C65/1606 , B29C65/1612 , B29C65/1619 , B29C65/1629 , B29C65/1632 , B29C65/1674 , B29C65/1696 , B29C65/7802 , B29C66/003 , B29C66/5227 , B29C66/63 , B29C66/71 , B29C66/73921 , B29C66/73941 , B29C66/81267 , B29C66/81423 , B29C66/81425 , B29C66/81431 , B29C66/83221 , B29K2709/02 , B29L2031/753 , B29L2031/7542 , B29K2083/00 , B29K2077/00 , B29K2075/02 , B29K2075/00 , B29K2071/00 , B29K2067/00 , B29K2063/00 , B29K2033/08 , B29K2027/12 , B29K2023/16 , B29K2023/00 , B29K2049/00 , B29K2033/12 , B29K2021/00
摘要： Methods of making medical devices are disclosed. In some embodiments, a method for welding together two components is described. The two components are non-coaxial and contact one another. A fixture holds the two components in a desired configuration. Electromagnetic radiation is directed at an area where the two components are in contact. The radiation causes the two portions to fuse together. The fixture has an open area or a transmissive material in the path of the electromagnetic radiation so that at least a portion of the radiation impinged up on the two components.
摘要翻译：披露了制造医疗器械的方法。在一些实施例中，描述了用于将两个部件焊接在一起的方法。两个部件是非同轴的并且彼此接触。夹具将两个部件保持在所需的配置中。电磁辐射指向两个部件接触的区域。辐射使两部分熔合在一起。固定装置在电磁辐射的路径中具有开放区域或透射材料，使得至少一部分辐射照射在两个部件上。

13. 发明授权

US08795348B2 Medical devices and related methods 有权
标题翻译：医疗器械及相关方法
公开(公告)号：US08795348B2
公开(公告)日：2014-08-05
申请号：US11152555
申请日：2005-06-14
申请人： Jan Weber , Thomas J. Holman , Scott Schewe
发明人： Jan Weber , Thomas J. Holman , Scott Schewe
IPC分类号： A61F2/06 , A61M29/00
CPC分类号： A61F2/95 , A61F2/91 , A61F2/958 , A61F2210/0033 , A61F2220/005 , A61F2220/0058 , A61F2250/0018 , A61F2250/0068 , A61M25/09 , A61M25/1006 , A61M25/10186 , A61M2025/1015 , A61M2025/105 , A61M2025/1056 , A61M2025/1068 , A61M2025/1086 , A61M2025/1093
摘要： A medical system including an elongate member and an elongate element associated with the elongate member so that a shape of the elongate member can be altered upon applying energy to the element.
摘要翻译：一种医疗系统，包括细长构件和与细长构件相关联的细长元件，使得在向元件施加能量时可以改变细长构件的形状。

14. 发明申请

US20110054394A1 BONDING SLEEVE FOR A MEDICAL DEVICE 有权
标题翻译：用于医疗设备的连接套管
公开(公告)号：US20110054394A1
公开(公告)日：2011-03-03
申请号：US12872882
申请日：2010-08-31
申请人： Matthew C. Heidner , Thomas J. Holman
发明人： Matthew C. Heidner , Thomas J. Holman
IPC分类号： A61M29/00 , B29C65/02
CPC分类号： A61F2/958 , A61F2002/9583
摘要： A medical device delivery system comprises an inner tube, a medical device disposed about a portion of the distal region of the inner tube, a medical device sheath disposed about the medical device, a medical device sheath retraction device extending proximally from the medical device sheath and an outer sheath disposed about a portion of the medical device sheath retraction device. The distal end of the outer sheath terminates at least one medical device length proximal of the medical device. The medical device sheath is movable relative to the outer sheath and relative to the inner tube.
摘要翻译：医疗装置输送系统包括内管，围绕内管的远端区域的一部分设置的医疗装置，围绕医疗装置设置的医疗装置护套，从医疗装置护套向近侧延伸的医疗装置护套收回装置，设置在所述医疗装置鞘缩回装置的一部分周围的外护套。外护套的远端终止医疗装置近端的至少一个医疗装置长度。医疗器械护套可相对于外护套和相对于内管移动。

15. 发明授权

US07691082B2 Medical devices 有权
标题翻译：医疗设备
公开(公告)号：US07691082B2
公开(公告)日：2010-04-06
申请号：US11174258
申请日：2005-07-01
申请人： James Lee Shippy, III , Thomas J. Holman
发明人： James Lee Shippy, III , Thomas J. Holman
IPC分类号： A61M31/00
CPC分类号： A61M25/1002 , A61M25/1029 , A61M25/1038 , A61M2025/1004 , A61M2025/1031 , A61M2025/1075 , A61M2025/1086 , Y10T428/139
摘要： Medical devices, for example, those that have balloons, and methods of making the devices are described. For example, in some embodiments, a medical device includes an elongated shaft, and an inflatable balloon carried by the shaft. The balloon includes a first recessed channel, a second recessed channel, a third recessed channel, and a fourth recessed channel, wherein the first recessed channel is spaced from the second recessed channel by a first distance, the third recessed channel is spaced from the fourth recessed channel by the first distance, and the second recessed channel is spaced from the third recessed channel by a second distance different than the first distance.
摘要翻译：描述了医疗设备，例如具有气球的设备，以及制造设备的方法。例如，在一些实施例中，医疗装置包括细长轴和由轴承载的可膨胀气囊。气球包括第一凹槽，第二凹槽，第三凹槽和第四凹槽，其中第一凹槽与第二凹槽相隔第一距离，第三凹槽与第四凹槽相隔，并且所述第二凹陷通道与所述第三凹陷通道间隔不同于所述第一距离的第二距离。

16. 发明申请

US20090125786A1 Mechanism for Adjacent-Symbol Error Correction and Detection 有权
标题翻译：相邻符号误差校正和检测机制
公开(公告)号：US20090125786A1
公开(公告)日：2009-05-14
申请号：US12354037
申请日：2009-01-15
申请人： James W. Alexander , Thomas J. Holman , Mark A. Heap , Stanley S. Kulick
发明人： James W. Alexander , Thomas J. Holman , Mark A. Heap , Stanley S. Kulick
IPC分类号： G11C29/04 , G06F11/07 , G06F11/22
CPC分类号： G11C29/42 , G11C11/401 , G11C2029/0409
摘要： According to one embodiment a computer system is disclosed. The computer system includes memory. The memory includes two or more rows, where each row has a plurality of memory devices. The computer system also includes a chipset. The chipset includes a detection/correction circuit to detect single and double symbol errors and correct single symbol errors for each memory row, and markers to maintain a log of errors within each memory row.
摘要翻译：根据一个实施例，公开了一种计算机系统。计算机系统包括内存。存储器包括两行或更多行，其中每行具有多个存储器件。计算机系统还包括芯片组。该芯片组包括一个检测/校正电路，用于检测单个和双重符号错误，并纠正每个存储器行的单个符号错误，以及标记以维护每个存储器行内的错误日志。

17. 发明授权

US07491188B2 Reinforced and drug-eluting balloon catheters and methods for making same 有权
标题翻译：加强和药物洗脱球囊导管及其制作方法
公开(公告)号：US07491188B2
公开(公告)日：2009-02-17
申请号：US10963272
申请日：2004-10-12
申请人： Thomas J. Holman , Jan Weber , Scott Schewe
发明人： Thomas J. Holman , Jan Weber , Scott Schewe
IPC分类号： A61M29/00
CPC分类号： A61M25/1029 , A61M25/10 , A61M25/1002 , A61M25/1034 , A61M25/1038 , A61M2025/0058 , A61M2025/1031 , A61M2025/105 , A61M2025/1084
摘要： The present invention generally relates to the field of intravascular medical devices, and more specifically to the field of balloon catheters and other similar diagnostic or therapeutic catheters within the body for treatment and diagnosis of diseases. In particular, the present invention relates to reinforced balloon catheters and drug-eluting balloon catheters and corresponding methods for producing same.
摘要翻译：本发明一般涉及血管内医疗装置的领域，更具体地涉及用于治疗和诊断疾病的体内气囊导管和其它类似的诊断或治疗导管领域。特别地，本发明涉及增强气囊导管和药物洗脱球囊导管及其相应的制造方法。

18. 发明授权

US07255711B2 Endovascular apparatus 失效
标题翻译：血管内装置
公开(公告)号：US07255711B2
公开(公告)日：2007-08-14
申请号：US10842754
申请日：2004-05-11
申请人： Thomas J. Holman , Fertac Bilge , Darlene A. Thometz , Paul J. Buscemi , David H. Donabedian
发明人： Thomas J. Holman , Fertac Bilge , Darlene A. Thometz , Paul J. Buscemi , David H. Donabedian
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61B17/12045 , A61B17/12118 , A61B2017/00004 , A61B2017/00535 , A61B2017/1205 , A61B2017/12127 , A61F2/89 , A61F2/94 , A61F2/95 , A61F2/954 , A61F2002/065 , A61F2002/072 , A61F2002/075 , A61F2250/0003
摘要： Percutaneous treatment of aortic aneurysms and like vascular anomalies by an apparatus and method wherein the apparatus is delivered via catheter and comprises a sleeve with at least one peripheral conduit which is caused to assume an expanded, rigid configuration by the introduction of a chemical or mechanical hardening means, whereby the sleeve is caused to assume an open cylindrical configuration for fluid flow therethrough.
摘要翻译：通过一种装置和方法经皮治疗主动脉瘤和类似的血管异常，其中该装置通过导管输送并且包括具有至少一个周边导管的套筒，其通过引入化学或机械硬化而被引入膨胀的刚性构型意味着使套筒呈现开口的圆柱形结构，用于流过其中的流体。

19. 发明授权

US06953470B2 Catheter support 有权
标题翻译：导管支持
公开(公告)号：US06953470B2
公开(公告)日：2005-10-11
申请号：US10241138
申请日：2002-09-11
申请人： Thomas J. Holman , Richard Dunn , Jan Seppala
发明人： Thomas J. Holman , Richard Dunn , Jan Seppala
IPC分类号： A61M25/00 , A61M29/02 , A61M29/00
CPC分类号： A61M25/104 , A61M25/0043 , A61M25/0054 , A61M25/0069 , A61M2025/1063
摘要： A balloon catheter comprises a balloon, an inner shaft, an outer shaft and a transition shaft. The transition shaft has a proximal portion and a distal portion joined by a tapered portion. The proximal portion has a diameter greater than the distal portion. The proximal portion has a first end portion engaged to at least a portion of the outer shaft at a first engagement site. At least a portion of the proximal waist is engaged to the proximal portion of the transition shaft at a second engagement site. At least a portion of the end region of the inner shaft is engaged to the distal portion of the transition shaft at a third engagement site. The distal portion extends through the balloon wherein at least a portion of the distal waist of the balloon is engaged to the distal portion of the transition shaft at a forth engagement site.
摘要翻译：球囊导管包括球囊，内轴，外轴和过渡轴。过渡轴具有通过锥形部分连接的近端部分和远端部分。近端部分的直径大于远端部分。近端部分具有在第一接合位置处接合到外轴的至少一部分的第一端部。近端腰部的至少一部分在第二接合位置处接合到过渡轴的近侧部分。内轴的端部区域的至少一部分在第三配合位置处接合到过渡轴的远端部分。远端部分延伸穿过球囊，其中球囊的远端腰部的至少一部分在第四接合位置处接合到过渡轴的远侧部分。

20. 发明授权

US06633947B1 Memory expansion channel for propagation of control and request packets 失效
标题翻译：用于传播控制和请求数据包的内存扩展通道
公开(公告)号：US06633947B1
公开(公告)日：2003-10-14
申请号：US09154063
申请日：1998-09-16
申请人： Thomas J. Holman , Peter D. MacWilliams
发明人： Thomas J. Holman , Peter D. MacWilliams
IPC分类号： G06F1200
CPC分类号： G06F13/1684 , G06F13/4243
摘要： A memory system comprising an expansion buffer and a memory expansion channel for connecting a large array of memory devices, such as Direct RDRAMs, to a memory controller. The memory devices are partitioned into subsets of memory devices so that each subset is connected to a unique memory channel for sending and receiving data. The expansion buffer and memory expansion channel provide communication with the memory devices via control packets on the expansion bus, where each control packet has a channel identification field to store a channel identifier; and via request packets on the expansion bus, where each request packet is associated with a control packet. The expansion buffer routes a request packet to a unique channel based upon the channel identifier stored in the associated control packet.
摘要翻译：一种存储器系统，包括扩展缓冲器和用于将诸如Direct RDRAM的大量存储器件连接到存储器控制器的存储器扩展通道。存储器件被划分为存储器件的子集，使得每个子集连接到用于发送和接收数据的唯一存储器通道。扩展缓冲器和存储器扩展通道通过扩展总线上的控制分组提供与存储器件的通信，其中每个控制分组具有用于存储信道标识符的信道标识字段; 并且经由扩展总线上的请求分组，其中每个请求分组与控制分组相关联。扩展缓冲器基于存储在相关联的控制分组中的信道标识符将请求分组路由到唯一信道。

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