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    • 12. 发明申请
    • System and method for patterning a master disk for nanoimprinting patterned magnetic recording disks
    • 用于图案化用于纳米压印图案化磁记录盘的母盘的系统和方法
    • US20070069429A1
    • 2007-03-29
    • US11241284
    • 2005-09-29
    • Thomas AlbrechtDennis McKeanGurinder SinghHenry Yang
    • Thomas AlbrechtDennis McKeanGurinder SinghHenry Yang
    • B29C35/08B29C67/00G02B1/12
    • G11B5/855
    • A system and method for patterning a master disk or “stamper” to be used for nanoimprinting magnetic recording disks uses an air-bearing slider that supports an aperture structure within the optical near-field of a resist layer on a rotating master disk substrate. Laser pulses directed to the input side of the aperture are output to the resist layer. The aperture structure includes a metal film reflective to the laser radiation with the aperture formed in it. The aperture has a size less than the wavelength of the incident laser radiation and is maintained by the air-bearing slider near the resist layer to within the radiation wavelength. The timing of the laser pulses is controlled to form a pattern of exposed regions in the resist layer, with this pattern ultimately resulting in the desired pattern of data islands and nondata islands in the magnetic recording disks when they are nanoimprinted by the master disk.
    • 用于图形化用于纳米压印磁记录盘的母盘或“压模”的系统和方法使用支撑旋转母盘衬底上的抗蚀剂层的光学近场内的孔结构的空气轴承滑块。 指向孔径输入侧的激光脉冲输出到抗蚀剂层。 孔结构包括反射激光辐射的金属膜,其中形成有孔。 孔径的尺寸小于入射激光辐射的波长,并且由抗蚀剂层附近的空气轴承滑块维持在辐射波长内。 控制激光脉冲的定时以形成抗蚀剂层中的暴露区域的图案,当这些图案被母盘纳米压印时,该图案最终导致磁记录盘中的数据岛和非数据岛的期望图案。
    • 13. 发明申请
    • Magnetic recording disk with patterned nondata islands of alternating polarity
    • 具有交替极性的图案化非磁性岛的磁记录盘
    • US20060280975A1
    • 2006-12-14
    • US11148918
    • 2005-06-09
    • Thomas AlbrechtZvonimir Bandic
    • Thomas AlbrechtZvonimir Bandic
    • G11B5/09B32B3/02G11B5/706
    • B82Y10/00G11B5/1278G11B5/59655G11B5/743G11B5/855
    • A magnetic recording disk has patterned nondata regions that are used for read/write head positioning and data synchronization. The nondata regions contain nondata islands of magnetizable material separated by nonmagnetic spaces with the nondata islands having alternating magnetization polarity in the along-the-track direction. In each nondata region, every other nondata island in the along-the track direction has the same magnetization direction, with adjacent nondata islands having antiparallel magnetization directions. The disk may be either a horizontal magnetic recording disk, wherein the antiparallel magnetization directions are in the plane of the recording layer and parallel to the along-the-track direction, or a perpendicular magnetic recording disk, wherein the antiparallel the magnetization directions are “into” and “out of” the recording layer.
    • 磁记录盘具有用于读/写头定位和数据同步的非图形区域。 非磁性区域包含由非磁性空间分离的可磁化材料的非磁性岛,其中沿着磁道方向具有交变磁化极性的非磁性岛。 在每个非数据区域中,沿轨道方向的每隔一个非数据岛具有相同的磁化方向,相邻的非数据岛具有反平行的磁化方向。 盘可以是水平磁记录盘,其中反平行磁化方向在记录层的平面中并且平行于轨道方向,或垂直磁记录盘,其中反并联的磁化方向为“ 进入“和”离开“记录层。
    • 15. 发明申请
    • Writing and reading of data in probe-based data storage devices
    • 在基于探测的数据存储设备中写入和读取数据
    • US20060072420A1
    • 2006-04-06
    • US10945224
    • 2004-09-20
    • Thomas AlbrechtTheodore AntonakopoulosGiovanni CherubiniAjay DholakiaEvangelos EleftheriouCharalampos Pozidis
    • Thomas AlbrechtTheodore AntonakopoulosGiovanni CherubiniAjay DholakiaEvangelos EleftheriouCharalampos Pozidis
    • G11B7/00
    • B82Y10/00G11B9/14G11B9/1436
    • Methods and apparatus are provided for controlling writing and reading of data in an array of A storage fields of a probe-based data storage device in which data is written to and read from the array of storage fields by a corresponding array of probes. One method uses the concept of sub-arrays to provide variable-rate read/write operation. Input data blocks are received for writing to the A-field array, each input data block being writable in A/k0 storage fields where k0 is an integer ≧2. For successive groups of k0 blocks, the k0 blocks are written to respective sub-arrays, each of A/k0 storage fields, of the storage field array by selectively writing at one of a series of rates, ranging from 1 block at a time to k0 blocks at a time, in dependence on a desired data write-rate. The blocks can also be read from the sub-arrays by selectively reading at one of a series of rates, ranging from 1 sub-array at a time to k0 sub-arrays at a time, in dependence on a desired data read-rate.
    • 提供了用于控制在基于探针的数据存储设备的A个存储区域阵列中的数据的写入和读取的方法和装置,其中通过相应的探针阵列将数据写入存储区阵列并从存储区域读取数据。 一种方法使用子阵列的概念来提供可变速率的读/写操作。 接收用于写入A字阵列的输入数据块,每个输入数据块可在A / k 0存储区域中写入,其中k <0>是整数> = 2 。 对于k个块的连续组,将k个0个块写入相应的子阵列,每个A / k 0个存储场, 根据期望的数据写入速率,通过以一系列速率中的一个选择性地写入,每次从一个块到每个块块一次块。 也可以通过选择性地以一系列速率中的一种读取从子阵列中读出的块,从一个子阵列一次一个子阵列到一个子阵列,依次 以期望的数据读取速率。
    • 18. 发明授权
    • Magnetic tape cartridge having brake with skirt portion thereof contacting reel hub continous wall portion
    • 具有制动器的磁带盒,裙带部分接触卷盘连续壁部分
    • US06563671B2
    • 2003-05-13
    • US10086245
    • 2002-03-04
    • Kiyoo MoritaHideaki ShigaDaisuke TakahashiYusuke IshiharaSeiji TsuyukiJeffrey S. McAllisterThomas AlbrechtRobert Ralph Heinze
    • Kiyoo MoritaHideaki ShigaDaisuke TakahashiYusuke IshiharaSeiji TsuyukiJeffrey S. McAllisterThomas AlbrechtRobert Ralph Heinze
    • G11B23107
    • G11B23/043G11B23/107
    • A magnetic tape cartridge includes a cartridge casing and a single reel which is contained in the cartridge casing for rotation. The reel has a reel hub in the form of a cylindrical member which has a bottom wall and is provided with an opening and a stopper gear formed on the bottom wall. A brake member is provided with a brake gear and is movable up and down between an operative position where the brake gear is brought into engagement with the stopper gear to prevent rotation of the reel and a retracted position where the brake gear is disengaged from the stopper gear to permit rotation of the reel. The brake member is normally urged toward the operative position and moved to the retracted position by a pusher member of a tape drive system which acts on the brake member through the opening in the reel hub when the magnetic tape cartridge is loaded in the tape drive system. A continuous wall portion is erected around the opening in the reel hub, and the brake member includes a horizontal portion and a continuous skirt portion which extends downward from the horizontal portion and is in contact with the continuous wall portion of the reel hub to close the opening together with the horizontal portion. The brake member is moved between the operative position and the retracted position with the skirt portion kept in cotact with the continuous wall portion of the reel hub.
    • 磁带盒包括盒壳体和容纳在盒壳体中用于旋转的单个卷轴。 卷轴具有圆筒形构件的形式的卷轴毂,其具有底壁,并且设置有形成在底壁上的开口和止动齿轮。 制动构件设置有制动器齿轮,并且可以在制动齿轮与止动齿轮啮合的操作位置之间上下移动,以防止卷轴旋转和制动器与止动器脱离的缩回位置 齿轮以允许卷轴旋转。 制动构件通常被推向操作位置,并且当磁带驱动系统的推动构件通过卷带盘毂中的开口作用在制动构件上时被推动到缩回位置,当磁带盒装入磁带驱动系统 。 连续的壁部分围绕卷轴轮毂中的开口竖立,并且制动部件包括从水平部分向下延伸并且与卷轴轮毂的连续壁部分接触的水平部分和连续的裙部,以闭合 与水平部分一起打开。 制动构件在操作位置和缩回位置之间移动,裙部保持与卷轴毂的连续壁部共同配合。
    • 19. 发明授权
    • Methods and compositions for treating viral infections
    • 用于治疗病毒感染的方法和组合物
    • US4849412A
    • 1989-07-18
    • US944301
    • 1986-12-19
    • Thomas AlbrechtChan H. LeeOdd S. Steinsland
    • Thomas AlbrechtChan H. LeeOdd S. Steinsland
    • A61K31/485A61K31/52A61K38/21A61K45/06
    • A61K45/06A61K31/485A61K31/52A61K38/212Y10S514/934
    • The disclosure demonstrates the inhibition of replication of human cytomegalovirus (HCMV) in cultured human embryo skin muscle cells by two separate subclasses of direct-acting smooth muscle relaxing agents alone or in combination with each other. These two subclasses are characterized mechanistically as calcium influx blockers (or calcium channel blockers) and cyclic nucleotide modulators. More specifically, the class of calcium influx blockers is exemplified by the drugs verapamil (and methoxyverapamil), nifedipine (the prototype drug of 1,4 dihydropyridines), and diltiazem. The class of cyclic nucleotide modulators is exemplified by the drugs isobutylmethylxanthine, papaverine (and its synthetic analog dioxyline), forskolin, and sodium nitroprusside. In addition, the present disclosure demonstrates that agents from one class, e.g., a calcium influx blocker, act synergistically when used in combination with agents from the other class, e.g., cyclic nucleotide modulators. The calcium influx blockers are shown to act synergistically when used in combination with alpha inThe government may own rights in the present invention pursuant to NIH contract NO1-AI42557.
    • 本公开内容显示了通过直接作用的平滑肌松弛剂单独或彼此组合的两个独立的亚类,抑制人巨细胞病毒(HCMV)在培养的人类胚胎皮肤细胞中的复制。 这两个亚类机械地表征为钙流入阻断剂(或钙通道阻滞剂)和环状核苷酸调节剂。 更具体地,钙流入阻断剂的类别是药物维拉帕米(和甲氧威韦帕米),硝苯地平(1,4二氢吡啶类的原型药物)和地尔硫卓。 环状核苷酸调节剂的类别由药物异丁基甲基黄嘌呤,罂粟碱(及其合成的模拟二恶草毒素),福斯高林和硝普钠钠来举例说明。 此外,本公开内容表明,当与来自另一类的试剂(例如环状核苷酸调节剂)组合使用时,来自一类的药剂,例如钙流入阻断剂,协同作用。 当与α-干扰素组合使用时,钙流出阻断剂显示出协同作用。 在另外的实施方案中,罂粟碱家族成员被证明与抗病毒核苷类似物协同地发挥抗病毒活性。
    • 20. 发明授权
    • Methods and compositions for treating viral infections
    • 用于治疗病毒感染的方法和组合物
    • US4800081A
    • 1989-01-24
    • US871120
    • 1986-06-05
    • Thomas AlbrechtChan H. Lee
    • Thomas AlbrechtChan H. Lee
    • A61K31/275A61K31/35A61K31/44A61K31/485A61K31/52A61K31/55A61K33/26A61K38/21A61K45/06A61K33/00A61K31/47
    • A61K45/06A61K31/275A61K31/35A61K31/44A61K31/485A61K31/52A61K31/55A61K33/26A61K38/212
    • The disclosure demonstrates the inhibition of replication of human cytomegalovirus (HCMV) in cultured human embryo skin muscle cells by two separate subclasses of direct-acting smooth muscle relaxing agents alone or in combination with each other. These two subclasses are characterized mechanistically as calcium influx blockers (or calcium channel blockers) and cyclic nucleotide modulators. More specifically, the class of calcium influx blockers is exemplified by the drugs verapamil (and methoxyverapamil), nifedipine (the prototype drug of 1,4 dihydropyridines), and diltiazem. The class of cyclic nucleotide modulators is exemplified by the drugs isobutylmethlyxanthine, papaverine (and its synthetic analog dioxyline), forskolin, and sodium nitroprusside. In addition, the present disclosure demonstrates that agents from one class, e.g., a calcium influx blocker, act synergistically when used in combination with agents from the other class, e.g., cyclic nucleotide modulators. Moreover, the calcium influx blockers are shown to act synergistically when used in combination with alpha interferon.
    • 本公开内容显示了通过直接作用的平滑肌松弛剂单独或彼此组合的两个独立的亚类,抑制人巨细胞病毒(HCMV)在培养的人类胚胎皮肤细胞中的复制。 这两个亚类机械地表征为钙流入阻断剂(或钙通道阻滞剂)和环状核苷酸调节剂。 更具体地,钙流入阻断剂的类别是药物维拉帕米(和甲氧威韦帕米),硝苯地平(1,4二氢吡啶类的原型药物)和地尔硫卓。 环状核苷酸调节剂的类别由药物异丁基甲基黄嘌呤,罂粟碱(及其合成的模拟二恶英),福斯高林和硝普钠等示例。 此外,本公开内容表明,当与来自另一类的试剂(例如环状核苷酸调节剂)组合使用时,来自一类的药剂,例如钙流入阻断剂,协同作用。 此外,当与α-干扰素组合使用时,显示出钙流入阻断剂的协同作用。