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11. 发明授权

US06999166B2 Component, apparatus, and method for analyzing molecules 失效
标题翻译：用于分析分子的组分，装置和方法
公开(公告)号：US06999166B2
公开(公告)日：2006-02-14
申请号：US10614723
申请日：2003-07-07
申请人： Tomohiko Matsushita , Takeo Nishikawa , Shigeru Aoyama
发明人： Tomohiko Matsushita , Takeo Nishikawa , Shigeru Aoyama
IPC分类号： G01N21/01 , G01N21/64
CPC分类号： G01N21/6452 , B01L3/5027 , G01N2021/6439 , G01N2021/6463 , G01N2021/6478 , G02B3/0062 , G02B3/0068 , G02B5/124 , G02B5/13 , G02B21/34
摘要： Components, apparatus, and method for detecting emission signals from target molecules include a substrate having a plurality of pixel locations on a surface, each location including at least one target molecule; a reflecting plate disposed opposite a side of the substrate having the pixel location; and a lens array disposed between the substrate and the reflecting plate, including the first lens array on the substrate side, a medium layer, and the second lens array on the reflecting plate side. Each lens of the second lens array has its focus on each lens of the first lens array, and the first lens array and the second lens array focus into an image of each of the at least one target molecule on the reflecting plate.
摘要翻译：用于检测来自目标分子的发射信号的组件，装置和方法包括：具有表面上的多个像素位置的衬底，每个位置包括至少一个靶分子; 反射板，与具有像素位置的所述基板的一侧相对设置; 以及设置在基板和反射板之间的透镜阵列，其包括在基板侧的第一透镜阵列，介质层和反射板侧上的第二透镜阵列。第二透镜阵列的每个透镜都聚焦在第一透镜阵列的每个透镜上，并且第一透镜阵列和第二透镜阵列聚焦成反射板上的至少一个目标分子中的每一个的图像。

12. 发明申请

US20080037022A1 Surface Plasmon Resonance Sensor 审中-公开
标题翻译：表面等离子体共振传感器
公开(公告)号：US20080037022A1
公开(公告)日：2008-02-14
申请号：US10589044
申请日：2005-02-10
申请人： Takeo Nishikawa , Shigeru Aoyama , Tomohiko Matsushita , Shigemi Norioka , Tetsuichi Wazawa
发明人： Takeo Nishikawa , Shigeru Aoyama , Tomohiko Matsushita , Shigemi Norioka , Tetsuichi Wazawa
IPC分类号： G01N21/55 , B05D5/12 , G02B5/28
CPC分类号： G01N21/554 , Y10T428/31678
摘要： In a surface plasmon resonance sensor including a chip with a substrate 102 and a metal layer 103, a prism 104, an optical system 105 serving as a light source, and a light detector 106, the metal layer 103 is configured by a flat part 109 formed into a thin film, and convex parts formed from metal particles 110 and the like arranged spaced apart from each other. When light enters the metal layer 103 of such configuration, resonance angle arising from the flat part 109 and the convex parts are respectively obtained. The change in index of refraction of a medium contacted by the metal layer is detected from such resonance angle.
摘要翻译：在包括具有基板102和金属层103的芯片的表面等离子体共振传感器，棱镜104，用作光源的光学系统105和光检测器106中，金属层103由平坦部分109 形成为薄膜，并且由彼此间隔开设置的金属颗粒110等形成的凸部。当光进入这种结构的金属层103时，分别获得从平坦部分109和凸起部分产生的共振角度。从这种共振角度检测与金属层接触的介质的折射率的变化。

13. 发明授权

US07906344B2 Localized plasmon resonance sensor and examining device 有权
标题翻译：局部等离子体共振传感器和检查装置
公开(公告)号：US07906344B2
公开(公告)日：2011-03-15
申请号：US10594698
申请日：2005-03-30
申请人： Tomohiko Matsushita , Shigeru Aoyama , Takeo Nishikawa , Shingo Nagaoka , Tetsuichi Wazawa
发明人： Tomohiko Matsushita , Shigeru Aoyama , Takeo Nishikawa , Shingo Nagaoka , Tetsuichi Wazawa
IPC分类号： G01N33/553
CPC分类号： G01N21/648 , Y10S435/808 , Y10S436/805
摘要： The metal fine particles 33 are sparsely fixed on the surface of the transparent substrate 32, and the acceptor 35 for attaching the specific ligand is immobilized on the transparent substrate 32 or the metal fine particles 33. The prism 36 is closely attached to the lower surface of the transparent substrate 32, and the excitation light enters the transparent substrate 32 through the prism 36. The incident light is totally reflected at the surface of the transparent substrate 32, and the evanescent light generated at the surface and the metal fine particles 33 locally plasmon resonate. As the evanescent light and the metal fine particles locally plasmon resonate, a strong electric field is enclosed in the vicinity of the metal fine particles. When the surface arranged with the metal fine particles 33 and the acceptor 35 is contacted to the analysis sample solution containing ligand modified with light emitting molecules, only the light emitting molecule modifying a specific ligand attached to the acceptor emits light.
摘要翻译：金属微粒33被稀疏地固定在透明基板32的表面上，用于附着特定配体的受主35被固定在透明基板32或金属微粒33上。棱镜36紧密地附着在下表面并且激发光通过棱镜36进入透明基板32.入射光在透明基板32的表面全反射，并且在表面产生的ev逝光和金属微粒33局部地反射等离子体共振。当瞬间光和金属微粒局部等离子体共振时，强电场被包围在金属微粒附近。当配置有金属微粒33和受体35的表面与含有用发光分子改性的配体的分析样品溶液接触时，只有修饰与受体相连的特定配体的发光分子发光。

14. 发明申请

US20050046758A1 Method of transcribing biomolecular patterns, method of manufacturing chip boards, and method of manufacturing biochips 失效
标题翻译：转录生物分子模式的方法，制造芯片板的方法以及制造生物芯片的方法
公开(公告)号：US20050046758A1
公开(公告)日：2005-03-03
申请号：US10902495
申请日：2004-07-29
申请人： Tomohiko Matsushita , Shigeru Aoyama , Takeo Nishikawa , Yuko Tsuda , Shigemi Norioka , Tetsuichi Wazawa
发明人： Tomohiko Matsushita , Shigeru Aoyama , Takeo Nishikawa , Yuko Tsuda , Shigemi Norioka , Tetsuichi Wazawa
IPC分类号： G01N33/53 , B81C1/00 , B81C99/00 , G01N33/48 , G01N33/50 , G01N35/00 , G01N37/00 , G02F1/017 , G02F1/13 , H01S5/34
CPC分类号： B82Y20/00 , B01J2219/00382 , B01J2219/00385 , B01J2219/00436 , B01J2219/00527 , B01J2219/00576 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00617 , B01J2219/00619 , B01J2219/00621 , B81B2201/0214 , B81B2201/06 , B81C1/00206 , B81C99/009 , B82Y5/00 , B82Y10/00 , G02F2001/01791 , G02F2202/32 , H01S5/3412
摘要： A method of mass-producing minute structures such as biochips, protein chips, quantum dots, and quantum chips involves arranging an antigen two-dimensionally on a board and arranging probes two-dimensionally facing the same direction so that the binding sites of the probes may bind to the antigen. An inorganic substance such as Ni is deposited on the board from the upper side of the probes by sputtering or evaporation to form a thin film layer and on the top surface of the flatly formed thin film layer, a supporting layer is formed by separating out the same inorganic substance using electrotyping. Then, by peeling the thin film layer and the supporting layer off of the board together, the mother stamper having cavities for the patterns of biomolecules is obtained.
摘要翻译：大规模生产生物芯片，蛋白质芯片，量子点和量子芯片的微小结构的方法包括将二维布置在板上，并将探针二维排列成相同的方向，使得探针的结合位点结合抗原。无机物质如Ni通过溅射或蒸发从探针的上侧沉积在板上以形成薄膜层，并且在平坦形成的薄膜层的顶表面上，通过分离出使用电化学的相同无机物质。然后，通过将薄膜层和支撑层从板上剥离在一起，获得具有用于生物分子图案的空腔的母模。

15. 发明授权

US07154576B2 LCD reflector with repetition pitch 失效
标题翻译：液晶反射器，重复间距
公开(公告)号：US07154576B2
公开(公告)日：2006-12-26
申请号：US10789394
申请日：2004-02-27
申请人： Tomohiko Matsushita , Shigeru Aoyama , Makoto Ohhira , Motohiko Matsushita , Yasuhiro Kawabata
发明人： Tomohiko Matsushita , Shigeru Aoyama , Makoto Ohhira , Motohiko Matsushita , Yasuhiro Kawabata
IPC分类号： G02F1/1335
CPC分类号： G02F1/133553
摘要： A reflector used for a display device has a plurality of unit reflecting portions. The unit reflecting portions are arranged by repeating arrangement patterns of unit regions. The unit regions have a repetition pitch that is integral times the pitch of pixels of a liquid crystal display and more than 5000 μm. More preferably, the repetition pitch of unit regions is integral times the pitch of pixels of a liquid crystal display and more than 10000 μm.
摘要翻译：用于显示装置的反射器具有多个单元反射部分。单元反射部分通过重复单元区域的布置图案来布置。单位区域具有与液晶显示器的像素间距成比例的重复间距，并且超过5000μm。更优选地，单位区域的重复间距是液晶显示器的像素的间距和超过10000μm的整数倍。

16. 发明授权

US6151166A Color separation element and image display device using same 失效
标题翻译：色分离元件和使用其的图像显示装置
公开(公告)号：US6151166A
公开(公告)日：2000-11-21
申请号：US81629
申请日：1998-05-19
申请人： Tomohiko Matsushita , Masayuki Shinohara , Shigeru Aoyama
发明人： Tomohiko Matsushita , Masayuki Shinohara , Shigeru Aoyama
IPC分类号： G02B5/04 , F21V8/00 , G02B5/18 , G02F1/1335 , G02F1/13357 , G02B27/44 , F21V7/04
CPC分类号： G02B6/0053 , G02B5/1814 , G02F1/133621 , G02F1/133504 , G02F1/133526 , G02F2201/305
摘要： A color image display device has a light source which emits an approximately parallel beam of light, a color separation element for separating this parallel beam into beams of light of different colors, a liquid crystal display panel having picture elements and a lens array for focusing the separated beams at corresponding ones of these picture elements. The color separation element is formed with a prism array having two diffraction gratings on both sides of it such that a beam of white light passing through it will be separated into beams of different colors and the angles between the optical axes of these beams of different colors will be greater as they leave the separation element than if this beam of white light passed through only one of these diffraction gratings. Either one or both of these diffraction gratings may be integrally formed respectively on one or both of the surfaces of the prism array.
摘要翻译：彩色图像显示装置具有发射大致平行光束的光源，用于将该平行光束分离成不同颜色的光束的分色元件，具有像素的液晶显示面板和用于聚焦的透镜阵列在这些图像元素的相应的那些分离的光束。该分色元件形成有棱镜阵列，其棱镜阵列在其两侧具有两个衍射光栅，使得通过它的白光束将被分离成不同颜色的光束，并且不同颜色的这些光束的光轴之间的角度当离开分离元件时会比通过这些衍射光栅中的一个的白色光束更大。这些衍射光栅中的一个或两个可以分别一体地形成在棱镜阵列的一个或两个表面上。

17. 发明申请

US20140209170A1 LAMINATED SHEET AND METHOD FOR PRODUCING THE SAME 审中-公开
标题翻译：层压片及其制造方法
公开(公告)号：US20140209170A1
公开(公告)日：2014-07-31
申请号：US14237699
申请日：2012-07-31
申请人： Ayako Shimazu , Atsushi Shiomi , Shigeru Aoyama , Kozo Takahashi
发明人： Ayako Shimazu , Atsushi Shiomi , Shigeru Aoyama , Kozo Takahashi
IPC分类号： H01L31/048 , B32B37/04 , B32B27/08
CPC分类号： B32B37/04 , B32B7/12 , B32B25/08 , B32B25/14 , B32B27/08 , B32B27/20 , B32B27/32 , B32B27/36 , B32B38/0012 , B32B2037/243 , B32B2038/0028 , B32B2255/10 , B32B2255/26 , B32B2270/00 , B32B2307/516 , B32B2307/734 , B32B2457/12 , H01L31/049 , Y02E10/50 , Y10T428/2495 , Y10T428/24967
摘要： A laminate sheet including a layer containing a polyester resin as a main component (P1 layer), an adhesive resin layer (P2 layer), and a layer containing a polyolefin resin as a main component (P3 layer), wherein the laminate sheet has a total thickness of at least 30 μm and up to 500 μm, the P2 layer has a thickness of at least 0.1 μm and up to 3 μm, and a ratio of the thickness of the P1 layer (P1) to the thickness of the P3 layer (P3) (ratio P1/P3) is at least 0.2 and up to 5.
摘要翻译：包含以聚酯树脂为主要成分（P1层）的层，粘合树脂层（P2层）和含有聚烯烃树脂作为主要成分的层（P3层）的层压片材，其中层压片材具有总厚度为30μm以上至500μm以下，P2层的厚度为0.1μm以上且3μm以下，P1层（P1）的厚度与P3层的厚度的比例（P3）（比率P1 / P3）为0.2以上，5以下。

18. 发明申请

US20100307570A1 POLYESTER FILM AND A PRODUCTION PROCESS THEREOF, AND A SURFACE LIGHT SOURCE, SOLAR BATTERY BACKSHEET AND SOLAR BATTERY RESPECTIVELY OBTAINED BY USING THE SAME 有权
标题翻译：聚酯薄膜及其生产工艺，以及表面光源，太阳能电池背板和使用相应方法获得的太阳能电池
公开(公告)号：US20100307570A1
公开(公告)日：2010-12-09
申请号：US12745028
申请日：2008-11-28
申请人： Shigeru Aoyama , Akikazu Kikuchi , Kozo Takahashi
发明人： Shigeru Aoyama , Akikazu Kikuchi , Kozo Takahashi
IPC分类号： B32B27/36 , C08J5/18 , B29C55/02 , H01L31/04 , F21V11/00
CPC分类号： C08J5/18 , B32B2367/00 , C08J2367/02 , C08L23/02 , C08L23/12 , C08L23/20 , C08L51/06 , C08L67/02 , C08L2205/03 , H01L31/049 , Y02E10/50 , Y10T428/254 , C08L2666/24
摘要： A polyester film includes a polyester layer (W layer) containing an aromatic polyester resin (A) and a component (B) incompatible with the polyester resin (A), wherein the incompatible component (B) contains an acid-denaturated polyolefin resin (b2) and is dispersed as dispersion pieces with a flatness of 10 or higher in the polyester layer (W layer), and wherein volume occupancy of the dispersion pieces in the polyester layer (W layer) is 3 vol % to less than 50 vol %, and volume occupancy of voids in the polyester layer (W layer) is less than 3 vol %.
摘要翻译：聚酯膜包括含有芳香族聚酯树脂（A）的聚酯层（W层）和与聚酯树脂（A）不相容的成分（B），其中不相容成分（B）含有酸变性聚烯烃树脂（b2 ），在聚酯层（W层）中分散为10以上的分散体，其中聚酯层（W层）中的分散体的体积占有率为3体积％〜小于50体积％并且聚酯层（W层）中空隙的体积占有率小于3体积％。

19. 发明授权

US07434976B2 Double-side display device with surface light source device having deflection patterns 失效
标题翻译：具有表面光源装置的双面显示装置具有偏转图案
公开(公告)号：US07434976B2
公开(公告)日：2008-10-14
申请号：US11376875
申请日：2006-03-16
申请人： Kenji Sakurai , Makoto Ohhira , Gouo Kurata , Akihiro Funamoto , Shigeru Aoyama
发明人： Kenji Sakurai , Makoto Ohhira , Gouo Kurata , Akihiro Funamoto , Shigeru Aoyama
IPC分类号： F21V7/04
CPC分类号： G02B6/0038 , G02B6/005
摘要： A double-side LCD having a surface light source device including a light guide plate and a light source facing one end face of the light guide plate. A plurality of deflection patterns are formed in a surface facing a light outgoing plane of the light guide plate, the deflection pattern includes an inclined plane facing the light source side and a re-incident plane substantially perpendicular to the light outgoing plane. Light from the light source is reflected by the inclined plane and outputted from the light outgoing plane to the LCD. A tilt angle (α) of the inclined plane satisfies: 45°−[Sin−1(Sin θ/n)]/2≦α≦45°+[Sin−1(Sin θ/n)]/2, wherein θ is an angle between a direction of peak brightness of outputted light and a direction perpendicular to the light outgoing plane, n is a refractive index of the light guide plate, and θ is within 6-15°.
摘要翻译：一种双面LCD，其具有包括导光板和面向光导板的一个端面的光源的表面光源装置。在面向导光板的光出射面的表面上形成多个偏转图案，偏转图案包括面向光源侧的倾斜平面和基本上垂直于光出射平面的再入射面。来自光源的光被倾斜平面反射并从光输出平面输出到LCD。倾斜面的倾斜角（α）满足：45° - [Sin ^{（Sinθ/ n）] / 2 <=α<= 45°+ [SIN < （Sinθ/ n）] / 2，其中θ是输出光的峰值亮度方向与垂直于光出射面的方向之间的角度，n是导光板的折射率， θ在6-15°以内。}

20. 发明授权

US07419770B2 Manufacturing method of optical device provided with resin thin film having micro-asperity pattern 有权
标题翻译：提供具有微凹凸图案的树脂薄膜的光学装置的制造方法
公开(公告)号：US07419770B2
公开(公告)日：2008-09-02
申请号：US10930728
申请日：2004-08-31
申请人： Masaaki Ikeda , Shigeru Aoyama
发明人： Masaaki Ikeda , Shigeru Aoyama
IPC分类号： G02B5/08
CPC分类号： G02B5/021 , B29C43/021 , B29C43/222 , B29C43/226 , B29C43/3697 , B29C59/026 , B29C59/046 , B29C2043/463 , B29C2059/023 , B29D11/00 , B29L2011/00 , B29L2011/0016 , G02B5/0215 , G02B5/0268 , G02B5/0284 , G02F1/133553 , G02F2203/03 , G03F7/38 , Y10T428/24917
摘要： A manufacturing method of an optical device having a micro-asperity pattern that has various kinds of accurate three-dimensional shapes and is realized as thin films includes: a first step of coating a substrate with a resin thin film made of a photosensitive resin; a second step of forming a material-property-changed part at a part of the resin thin film by photolithography; a third step of controlling a temperature of the resin thin film to be a temperature that is lower than a photosensitivity extinction temperature or a hardening reaction starting temperature of the resin thin film; a fourth step of pressing a die having a micro-asperity pattern against the surface of the resin thin film to form a first micro-asperity pattern in a state in which the resin thin film has been softened or melted; and a fifth step of forming a second micro-asperity pattern at a part of the resin thin film by removing the material-property-changed part.
摘要翻译：具有具有各种精确三维形状并实现为薄膜的微凹凸图案的光学装置的制造方法包括：第一步骤，用由感光树脂制成的树脂薄膜涂覆基板; 通过光刻法在树脂薄膜的一部分上形成材料性质变化部分的第二步骤; 将树脂薄膜的温度控制为低于树脂薄膜的光敏消光温度或硬化反应开始温度的温度的第三步骤; 在树脂薄膜软化或熔化的状态下，将具有微凹凸图案的模具压在树脂薄膜的表面上以形成第一微凹凸图案的第四步骤; 以及通过去除材料性质改变部分在树脂薄膜的一部分上形成第二微凹凸图案的第五步骤。

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