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    • 11. 发明授权
    • Focused stimulation in a medical stimulation device
    • 在医疗刺激装置中聚焦刺激
    • US09566433B2
    • 2017-02-14
    • US12979676
    • 2010-12-28
    • Christopher van den Honert
    • Christopher van den Honert
    • A61N1/00A61N1/36H04R25/00A61N1/05A61N1/32
    • A61N1/36036A61N1/0541A61N1/323H04R25/305H04R25/606
    • A medical stimulation device such as a cochlear implant configured to provide stimulation of one or more spatially-restricted contiguous portion(s) of the spiral array of auditory nerve fibers in the cochlear (“discrete stimulation regions”). Each discrete stimulation region is defined by the constructive and/or destructive interference of stimulating and limiting signals simultaneously applied to electrode channels of an implanted electrode array, the stimulating and limiting signals being determined based upon transimpedance measurements of intracochlear electrode channels of the implanted electrode array representing specific spread functions of an individual recipient. The stimulating signal is preferably applied through a targeted electrode channel; that is, one or more successive electrodes which is/are adjacent to the discrete stimulation region. The targeted electrode channel is selected to represent a sound based on the outputs of a sound processor to stimulate neural activity in the discrete stimulation region to thereby cause a percept of the represented sound. The size of the discrete stimulation region is defined by the limiting signal(s) applied to electrode channel(s) other than the targeted electrode channel, and which negate(s) current spread which would otherwise occur in response to the stimulating signal.
    • 医疗刺激装置,例如耳蜗植入物,被配置成在耳蜗(“离散刺激区域”)中提供听觉神经纤维螺旋阵列的一个或多个空间受限的连续部分的刺激。 每个离散刺激区域由同时施加到植入电极阵列的电极通道的刺激和限制信号的结构性和/或相消干扰限定,刺激和限制信号基于植入电极阵列的耳内电极通道的跨阻抗测量来确定 代表个人收件人的具体传播功能。 刺激信号优选通过目标电极通道施加; 即与离散刺激区域相邻的一个或多个连续电极。 选择目标电极通道以基于声音处理器的输出来表示声音,以刺激离散刺激区域中的神经活动,从而引起对所示声音的感知。 离散刺激区域的大小由施加到目标电极通道之外的电极通道的限制信号定义,并且否定当前的扩展,否则这些电流扩展响应于刺激信号而发生。
    • 12. 发明申请
    • MULTI-ELECTRODE CHANNEL CONFIGURATIONS
    • 多电极通道配置
    • US20110288613A1
    • 2011-11-24
    • US12782604
    • 2010-05-18
    • Zachary M. SmithChristopher van den Honert
    • Zachary M. SmithChristopher van den Honert
    • A61N1/05
    • A61N1/36032A61N1/0541A61N1/36036A61N1/37264H03G9/005H04R25/70
    • An apparatus and method for determining stimulation channels for a stimulating device is provided. This method and apparatus may involve computing a set of weights for the plurality of stimulation channels of the stimulating hearing prosthesis. These weights may be determined by determining a transimpedance matrix for the stimulating hearing prosthesis where a diagonal of the transimpedance matrix is determined by extrapolation. A transadmittance matrix may then be computed for this transimpedance matrix. An error may then be computed base on positive off-diagonal terms of the transadmittance matrix. The apparatus and method may determine the weights for the stimulation channels by determining an adjustment to the diagonal of the transimpedance matrix that results in a computed error that does not exceed a specified criterion level.
    • 提供了一种用于确定刺激装置的刺激通道的装置和方法。 该方法和装置可以包括计算刺激性听觉假体的多个刺激通道的一组权重。 这些权重可以通过确定用于刺激性听力假体的跨阻抗矩阵来确定,其中跨阻抗矩阵的对角线通过外推来确定。 然后可以为该跨阻抗矩阵计算交纳导纳矩阵。 然后可以基于导纳矩阵的正偏离对角项来计算误差。 该装置和方法可以通过确定导致计算出的误差不超过指定标准水平的跨阻抗矩阵的对角线来确定刺激通道的权重。
    • 13. 发明授权
    • Array of bipolar electrodes
    • 双极电极阵列
    • US5000194A
    • 1991-03-19
    • US236516
    • 1988-08-25
    • Christopher van den HonertDavid C. Michow
    • Christopher van den HonertDavid C. Michow
    • A61F11/04A61N1/05
    • A61N1/0541A61F11/04
    • The invention provides an array of electrodes suitable for use as an auditory prosthesis. The array comprises a carrier member formed from electrically insulating flexible material, having a surface and a core, the carrier member including at least a pair of electrodes molded therein, the electrodes comprising a length of contact material formed in a semi-circular shape, having a convex contact surface and a locking portion defining an internal space. The electrode is molded in the carriers so that the convex contact surface of the electrode is preferably flush with the carrier member surface. The locking portion of the electrode is molded into the core of the carrier member in the electrode connected to a lead wire which is molded in the core of the carrier member. The invention further provides a method for fabricating such an array of bipolar electrodes.
    • 本发明提供了适合用作听觉假体的电极阵列。 阵列包括由电绝缘的柔性材料形成的载体部件,具有表面和芯部,所述载体部件至少包括一对模制在其中的电极,所述电极包括形成为半圆形的一定长度的接触材料, 凸接触表面和限定内部空间的锁定部分。 电极被模制在载体中,使得电极的凸形接触表面优选地与载体构件表面齐平。 电极的锁定部分被模制到与形成在承载部件的芯部中的引线相连接的电极中的载体部件的芯部中。 本发明还提供了制造这种双极电极阵列的方法。
    • 14. 发明授权
    • Method for determining absolute current density through an implanted
electrode
    • 通过植入电极确定绝对电流密度的方法
    • US4944301A
    • 1990-07-31
    • US207774
    • 1988-06-16
    • Gregory P. WidinChristopher van den Honert
    • Gregory P. WidinChristopher van den Honert
    • A61N1/05A61N1/36
    • A61N1/36032A61N1/05
    • A method for determining absolute current density through an implanted electrode measures the fundamental and harmonic components of an electrical current passing through the electrode and estimates the absolute current density from the ratio between the magnitude of the electrical current measured at one of the harmonics on the fundamental frequency. Another method of the invention applies a wideband noise input voltage to the electrode under investigation and measures the spectrum of the input voltage and output current to determine a first transfer function. A second transfer function representing an increase magnitude of wideband noise input voltage is also obtained. A difference transfer function is computed and used to determine absolute current density through the electrode. The methods may be practiced non-invasively.
    • 用于通过注入电极确定绝对电流密度的方法测量通过电极的电流的基波和谐波分量,并根据在基波的一个谐波上测量的电流的大小之间的比率来估计绝对电流密度 频率。 本发明的另一种方法是对正在研究的电极施加宽带噪声输入电压,并测量输入电压和输出电流的频谱以确定第一传递函数。 还获得了表示宽带噪声输入电压的增加幅度的第二传递函数。 计算差分传递函数并用于确定通过电极的绝对电流密度。 这些方法可以非侵入式地实施。
    • 16. 发明授权
    • Independent and concurrent processing multiple audio input signals in a prosthetic hearing implant
    • 在辅助听力植入物中独立并且处理多个音频输入信号
    • US08369958B2
    • 2013-02-05
    • US11335563
    • 2006-01-20
    • Bomjun KwonChristopher van den Honert
    • Bomjun KwonChristopher van den Honert
    • A61N1/00A61N5/04
    • A61N1/36036
    • A prosthetic hearing implant capable of independently and concurrently processing multiple audio input signals such that each audio input signal is separately utilized to stimulate the basilar membrane of the implant recipient. A prosthetic hearing implant of the present invention simultaneously receives discrete audio signals from each of one or more audio sources, generates a separate set of one or more stimulations signals for each audio signal, and concurrently applies the stimulation signals to the cochlear. Different channels of stimulation may be allocated to each audio input signal. Alternatively, different modes of stimulation may be used for each input signal. Or, in yet another example, the audio input signals may be time-multiplexed such that the input signals are applied in alternating timeslots. Or, in yet other examples, the input signals may be applied using a combination of stimulation channels, modes of stimulation, and alternating time slots. The stimulation signals may be delivered to the same or different electrodes depending on the quantity and frequency component of the received audio input signals, the quantity of available stimulation channels, and other factors.
    • 能够独立并且同时处理多个音频输入信号的假体听力植入物,使得每个音频输入信号被分开地用于刺激植入物接受者的基底膜。 本发明的假体听力植入物同时从一个或多个音频源中的每一个接收离散音频信号,为每个音频信号产生一个或多个刺激信号的单独集合,并且同时将刺激信号施加到耳蜗。 可以将不同的刺激通道分配给每个音频输入信号。 或者,可以对每个输入信号使用不同的刺激模式。 或者,在另一示例中,音频输入信号可以被时分复用,使得输入信号以交替的时隙被应用。 或者,在其他示例中,可以使用刺激通道,刺激模式和交替时隙的组合来应用输入信号。 刺激信号可以根据所接收的音频输入信号的数量和频率分量,可用刺激通道的数量和其他因素而传送到相同或不同的电极。
    • 19. 发明授权
    • Multi-electrode channel configurations for a hearing prosthesis
    • 用于听觉假体的多电极通道配置
    • US09031661B2
    • 2015-05-12
    • US12782604
    • 2010-05-18
    • Zachary M. SmithChristopher van den Honert
    • Zachary M. SmithChristopher van den Honert
    • A61N1/05A61N1/36H04R25/00H03G9/00
    • A61N1/36032A61N1/0541A61N1/36036A61N1/37264H03G9/005H04R25/70
    • An apparatus and method for determining stimulation channels for a stimulating device is provided. This method and apparatus may involve computing a set of weights for the plurality of stimulation channels of the stimulating hearing prosthesis. These weights may be determined by determining a transimpedance matrix for the stimulating hearing prosthesis where a diagonal of the transimpedance matrix is determined by extrapolation. A transadmittance matrix may then be computed for this transimpedance matrix. An error may then be computed base on positive off-diagonal terms of the transadmittance matrix. The apparatus and method may determine the weights for the stimulation channels by determining an adjustment to the diagonal of the transimpedance matrix that results in a computed error that does not exceed a specified criterion level.
    • 提供了一种用于确定刺激装置的刺激通道的装置和方法。 该方法和装置可以包括计算刺激性听觉假体的多个刺激通道的一组权重。 这些权重可以通过确定用于刺激性听力假体的跨阻抗矩阵来确定,其中跨阻抗矩阵的对角线通过外推来确定。 然后可以为该跨阻抗矩阵计算交纳导纳矩阵。 然后可以基于导纳矩阵的正偏离对角项来计算误差。 该装置和方法可以通过确定导致计算出的误差不超过指定标准水平的跨阻抗矩阵的对角线来确定刺激通道的权重。
    • 20. 发明授权
    • Active electrode state control system
    • 有源电极状态控制系统
    • US09008787B2
    • 2015-04-14
    • US12771917
    • 2010-04-30
    • Paul M. CarterTorsten LehmannChristopher van den HonertIbrahim IbrahimTony M. Nygard
    • Paul M. CarterTorsten LehmannChristopher van den HonertIbrahim IbrahimTony M. Nygard
    • A61N1/36
    • A61N1/36032A61N1/36036
    • A method and system for charge imbalance compensation in a stimulating medical device is provided. The stimulating medical device includes at least one electrode contact configured for providing stimulation to a recipient. A charge imbalance compensation system in the stimulating medical device measures any residual charge remaining on the electrode contact that may result from an imbalance in the applied stimulation. If the measured residual charge exceeds a threshold, the charge imbalance compensation system causes a compensator current to be applied to reduce the residual charge. This residual charge may be measured by measuring a potential difference between the electrode contact and a reference electrode; or, by measuring a potential difference across a capacitor in-series with the electrode contact.
    • 提供了一种刺激性医疗装置中的电荷不平衡补偿的方法和系统。 刺激性医疗装置包括至少一个被配置用于向接受者提供刺激的电极接触件。 刺激性医疗装置中的电荷不平衡补偿系统测量可能由所施加的刺激的不平衡引起的电极接触上残留的剩余电荷。 如果测量的剩余电量超过阈值,则电荷不平衡补偿系统会引起补偿电流以减少剩余电荷。 可以通过测量电极接触和参考电极之间的电位差来测量该剩余电荷; 或者通过测量与电极接触件串联的电容器的电位差来测量。