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11. 发明申请

US20130210048A1 METHOD OF DETECTING A BIOLOGICAL ACTIVITY 审中-公开
标题翻译：检测生物活性的方法
公开(公告)号：US20130210048A1
公开(公告)日：2013-08-15
申请号：US13825143
申请日：2011-10-28
申请人： Sailaja Chandrapati , Heather M. Webb , Jeffrey C. Pederson , Brian J. Engel
发明人： Sailaja Chandrapati , Heather M. Webb , Jeffrey C. Pederson , Brian J. Engel
IPC分类号： C12Q1/22 , C12Q1/04
CPC分类号： C12Q1/22 , C12Q1/04
摘要： A method of detecting a biological activity is provided. The method includes contacting; in a liquid medium selected to facilitate a predetermined biological activity; a sample, an indicator reagent, and a substrate that receives and concentrates a biological derivative of the indicator reagent. The method further includes observing a portion of the substrate to detect the biological derivative. The method can be used to detect the presence or absence of a target cell.
摘要翻译：提供了检测生物活性的方法。该方法包括接触; 在选择用于促进预定生物活性的液体介质中; 样品，指示剂试剂和接收并浓缩指示剂试剂的生物衍生物的底物。该方法还包括观察基底的一部分以检测生物衍生物。该方法可用于检测靶细胞的存在或不存在。

12. 发明授权

US08980622B2 Biological sterilization indicator and method of using same 有权
标题翻译：生物灭菌指标及其使用方法
公开(公告)号：US08980622B2
公开(公告)日：2015-03-17
申请号：US13384886
申请日：2010-07-06
申请人： Jeffrey D. Smith , Jeffrey C. Pederson , Sailaja Chandrapati
发明人： Jeffrey D. Smith , Jeffrey C. Pederson , Sailaja Chandrapati
IPC分类号： C12M1/34 , A61L2/28 , C12Q1/22
CPC分类号： C12Q1/22 , A61L2/28
摘要： A biological sterilization indicator (BI) and a method of using same for assaying the lethality of a sterilization process. The BI can include a housing, which can include a first portion, and a second portion, which can be movable with respect to the first portion between a first and second position. The BI can further include a frangible container comprising a liquid. The BI can further include a spore reservoir and a projection positioned in the housing. The projection can be configured to fracture the container when the second portion of the housing is moved from the first position to the second position. The method can include maintaining a minimal cross-sectional area of space around the container when the second portion of the housing is in the first position, and fracturing the container in response to moving the second portion between the first and second positions.
摘要翻译：生物灭菌指示剂（BI）及其用于测定灭菌过程的致死性的方法。 BI可以包括可以包括第一部分的壳体和可以在第一和第二位置之间相对于第一部分移动的第二部分。 BI可进一步包括包含液体的易碎容器。 BI还可以包括孢子贮存器和位于壳体中的突起。当壳体的第二部分从第一位置移动到第二位置时，突起可被构造成使容器破裂。该方法可以包括当壳体的第二部分处于第一位置时保持围绕容器的最小的空间横截面面积，并响应于在第一和第二位置之间移动第二部分而破裂容器。

13. 发明申请

US20120149094A1 Biological Sterilization Indicator and Method of Using Same 有权
标题翻译：生物灭菌指标及其使用方法
公开(公告)号：US20120149094A1
公开(公告)日：2012-06-14
申请号：US13384886
申请日：2010-07-06
申请人： Jeffrey D. Smith , Jeffrey C. Pederson , Sailaja Chandrapati
发明人： Jeffrey D. Smith , Jeffrey C. Pederson , Sailaja Chandrapati
IPC分类号： C12M1/34 , C12M1/40
CPC分类号： C12Q1/22 , A61L2/28
摘要： A biological sterilization indicator (BI) and a method of using same for assaying the lethality of a sterilization process. The BI can include a housing, which can include a first portion, and a second portion, which can be movable with respect to the first portion between a first and second position. The BI can further include a frangible container comprising a liquid. The BI can further include a spore reservoir and a projection positioned in the housing. The projection can be configured to fracture the container when the second portion of the housing is moved from the first position to the second position. The method can include maintaining a minimal cross-sectional area of space around the container when the second portion of the housing is in the first position, and fracturing the container in response to moving the second portion between the first and second positions.
摘要翻译：生物灭菌指示剂（BI）及其用于测定灭菌过程的致死性的方法。 BI可以包括可以包括第一部分的壳体和可以在第一和第二位置之间相对于第一部分移动的第二部分。 BI可进一步包括包含液体的易碎容器。 BI还可以包括孢子贮存器和位于壳体中的突起。当壳体的第二部分从第一位置移动到第二位置时，突出部可以构造成使容器破裂。该方法可以包括当壳体的第二部分处于第一位置时保持围绕容器的最小的空间横截面面积，并且响应于在第一和第二位置之间移动第二部分来压裂容器。

14. 外观设计

USD665509S1 Sterility indicator vial 有权
标题翻译：无菌指示剂小瓶
公开(公告)号：USD665509S1
公开(公告)日：2012-08-14
申请号：US29378224
申请日：2010-11-01
申请人： Jeffrey D. Smith , Jeffrey C. Pederson , Sailaja Chandrapati
设计人： Jeffrey D. Smith , Jeffrey C. Pederson , Sailaja Chandrapati

15. 发明授权

US08840837B2 Biological sterilization indicator and method of using same 有权
标题翻译：生物灭菌指标及其使用方法
公开(公告)号：US08840837B2
公开(公告)日：2014-09-23
申请号：US13881154
申请日：2011-10-28
申请人： Jeffrey D. Smith , Jeffrey C. Pederson , Sailaja Chandrapati , RuthAnn R. Duda
发明人： Jeffrey D. Smith , Jeffrey C. Pederson , Sailaja Chandrapati , RuthAnn R. Duda
IPC分类号： C12Q1/22 , C12Q1/02
CPC分类号： C12Q1/22
摘要： A biological sterilization indicator (BI) and method of using same. The BI can include a housing, and a container positioned in the housing. The container can contain a liquid and at least a portion of the container can be frangible. The BI can further include a first chamber and a second chamber. The second chamber can include at least one source of biological activity. The BI can further include a first fluid path positioned to fluidly couple the first chamber and the second chamber, and a second fluid path positioned to allow displaced gas to move out of the second chamber. The method can include moving displaced gas out of the second chamber via the second fluid path as a sterilant is moved into the second chamber via the first fluid path and/or as the liquid is moved into the second chamber via the first fluid path.
摘要翻译：生物灭菌指示剂（BI）及其使用方法。 BI可以包括壳体和位于壳体中的容器。容器可以容纳液体，容器的至少一部分可以是易碎的。 BI还可以包括第一室和第二室。第二室可以包括至少一种生物活性来源。 BI还可以包括定位成流体耦合第一室和第二室的第一流体路径，以及定位成允许排出的气体移出第二室的第二流体路径。该方法可以包括当消毒剂经由第一流体路径移动到第二室中时和/或当液体经由第一流体路径移动到第二室中时，通过第二流体路径将移动的气体移出第二室。

16. 发明申请

US20130302849A1 BIOLOGICAL STERILIZATION INDICATOR AND METHOD OF USING SAME 有权
公开(公告)号：US20130302849A1
公开(公告)日：2013-11-14
申请号：US13881154
申请日：2011-10-28
申请人： Jeffrey D. Smith , Jeffrey C. Pederson , Sailaja Chandrapati , RuthAnn R. Duda
发明人： Jeffrey D. Smith , Jeffrey C. Pederson , Sailaja Chandrapati , RuthAnn R. Duda
IPC分类号： C12Q1/22
CPC分类号： C12Q1/22
摘要： A biological sterilization indicator (BI) and method of using same. The BI can include a housing, and a container positioned in the housing. The container can contain a liquid and at least a portion of the container can be frangible. The BI can further include a first chamber and a second chamber. The second chamber can include at least one source of biological activity. The BI can further include a first fluid path positioned to fluidly couple the first chamber and the second chamber, and a second fluid path positioned to allow displaced gas to move out of the second chamber. The method can include moving displaced gas out of the second chamber via the second fluid path as a sterilant is moved into the second chamber via the first fluid path and/or as the liquid is moved into the second chamber via the first fluid path.

17. 外观设计

USD638951S1 Sample processing disk cover 有权
公开(公告)号：USD638951S1
公开(公告)日：2011-05-31
申请号：US29350264
申请日：2009-11-13
申请人： William Bedingham , Peter D. Ludowise , Jeffrey C. Pederson , Barry W. Robole
设计人： William Bedingham , Peter D. Ludowise , Jeffrey C. Pederson , Barry W. Robole

18. 发明授权

US08834792B2 Systems for processing sample processing devices 有权
标题翻译：样品处理装置处理系统
公开(公告)号：US08834792B2
公开(公告)日：2014-09-16
申请号：US12617921
申请日：2009-11-13
申请人： Barry W. Robole , William Bedingham , Peter D. Ludowise , Jeffrey C. Pederson
发明人： Barry W. Robole , William Bedingham , Peter D. Ludowise , Jeffrey C. Pederson
IPC分类号： G01N9/30 , G01N21/00 , B01L3/00 , B01L7/00
CPC分类号： B01L3/5027 , B01L7/52 , B01L2300/046 , B01L2300/0803 , B01L2300/0861 , B01L2300/1883 , Y10T436/11
摘要： A system and method for processing sample processing devices. The system can include a base plate adapted to rotate about a rotation axis. The system can further include a cover including a first projection, and a housing. A portion of the housing can be movable with respect to the base plate between an open position and a closed position, and can include a second projection. The first projection and the second projection can be adapted to be coupled together when the portion is in the open position and decoupled when the portion is in the closed position. The method can include coupling the cover to the portion of the housing, moving the portion of the housing from the open position to the closed position, and rotating the base plate about the rotation axis.
摘要翻译：一种处理样品处理装置的系统和方法。该系统可以包括适于围绕旋转轴线旋转的基板。该系统还可以包括包括第一突起和壳体的盖。壳体的一部分可以相对于基板在打开位置和关闭位置之间移动，并且可以包括第二突起。当该部分处于打开位置时，第一突起和第二突出部可以适于联接在一起，并且当该部分处于关闭位置时该第一突出部和第二突出部分被解耦。该方法可以包括将盖连接到壳体的部分，将壳体的部分从打开位置移动到关闭位置，并且使基板围绕旋转轴线旋转。

19. 外观设计

USD638550S1 Sample processing disk cover 有权
标题翻译：样品处理盘盖
公开(公告)号：USD638550S1
公开(公告)日：2011-05-24
申请号：US29350262
申请日：2009-11-13
申请人： William Bedingham , Peter D. Ludowise , Jeffrey C. Pederson , Barry W. Robole
设计人： William Bedingham , Peter D. Ludowise , Jeffrey C. Pederson , Barry W. Robole

20. 外观设计

USD667561S1 Sample processing disk cover 有权
标题翻译：样品处理盘盖
公开(公告)号：USD667561S1
公开(公告)日：2012-09-18
申请号：US29384821
申请日：2011-02-04
申请人： William Bedingham , Peter D. Ludowise , Jeffrey C. Pederson , Barry W. Robole
设计人： William Bedingham , Peter D. Ludowise , Jeffrey C. Pederson , Barry W. Robole

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