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11. 发明授权

US07114520B2 Pressure regulator 有权
公开(公告)号：US07114520B2
公开(公告)日：2006-10-03
申请号：US11217104
申请日：2005-08-31
申请人： Roger Massengale , Stanley E. Fry , Charles J. McPhee
发明人： Roger Massengale , Stanley E. Fry , Charles J. McPhee
IPC分类号： F16K37/00
CPC分类号： G05D16/0647 , Y10S137/903 , Y10T137/0379 , Y10T137/0396 , Y10T137/0497 , Y10T137/7825 , Y10T137/7871 , Y10T137/7922 , Y10T137/8225 , Y10T137/8326
摘要： A variable device for regulating the outlet pressure of a fluid from a valve body, includes a pressure-sensing chamber having a wall formed by a resilient self-restoring diaphragm which is responsive to pressure in the chamber. A valve element connected to the diaphragm controls flow into the chamber. Increased pressure in the chamber decreases the flow into the chamber and decreasing pressure increases flow whereby fluid flow out from the chamber is maintained at a desired pressure. The outlet pressure is adjusted by deflecting the diaphragm in a direction to open the valve while permitting a section of the diaphragm connected to the valve member to remain responsive to the pressure in the chamber. An adjustment cover is provided to adjustably deflect the diaphragm and includes a catch mechanism to allow adjustment of the fluid outlet pressures and also retain the device at a desired value. An indicator arrangement may be provided to visually indicate the fluid outlet pressure.

12. 发明授权

US09084870B2 Catheter for uniform delivery of medication 有权
标题翻译：导管统一服药
公开(公告)号：US09084870B2
公开(公告)日：2015-07-21
申请号：US13238497
申请日：2011-09-21
申请人： Jose Castillo Deniega , Roger Massengale , Kenneth W. Rake
发明人： Jose Castillo Deniega , Roger Massengale , Kenneth W. Rake
IPC分类号： A61M25/14 , A61M25/00
CPC分类号： A61M25/0074 , A61M25/00 , A61M25/0023 , A61M25/0043 , A61M25/0068 , A61M25/0069 , A61M25/007 , A61M2025/0037 , A61M2025/0039 , A61M2025/0057 , A61M2025/0073
摘要： The present invention provides a catheter for the delivery of fluid medication across an anatomical region. In accordance with some embodiments, the catheter includes a tube having a plurality of exit holes in a side wall of the tube and an elongated member positioned within the tube. The exit holes combine to form a flow-restricting orifice of the catheter. Advantageously, fluid within the catheter flows through all of the exit holes, resulting in uniform distribution of fluid within an anatomical region.
摘要翻译：本发明提供一种用于在解剖区域上输送流体药物的导管。根据一些实施例，导管包括在管的侧壁中具有多个出口孔的管和位于管内的细长构件。出口孔结合形成导管的限流孔。有利地，导管内的流体流过所有出口孔，导致流体在解剖区域内的均匀分布。

13. 发明授权

US08343135B2 Anti-microbial catheter 有权
公开(公告)号：US08343135B2
公开(公告)日：2013-01-01
申请号：US12415304
申请日：2009-03-31
申请人： James Dal Porto , Jose Castillo Deniega , Roger Massengale , Kenneth W. Rake , Lois Rake, legal representative , Kevin Forest , Mark Siminuk
发明人： James Dal Porto , Jose Castillo Deniega , Roger Massengale , Kenneth W. Rake , Kevin Forest , Mark Siminuk
IPC分类号： A61M25/00
CPC分类号： A61L27/54 , A61L29/16 , A61L2300/104 , A61L2300/404 , A61M25/0045 , A61M25/0069 , A61M25/007 , A61M25/0071 , A61M2025/0056 , A61M2025/0057
摘要： A catheter having features configured to provide a substantially uniform flow rate of a fluid exiting the catheter and also exhibits anti-microbial properties. The uniform flow rate features may include one or more of a flow restricting membrane or flow restricting component within an infusion section of the catheter. In other arrangements, exit holes defining the infusion section of the catheter may be configured to provide the desired uniform flow rate over the length of the infusion section. Furthermore, the catheter also includes anti-microbial properties to inhibit the growth of microbes on or within the catheter and, preferably, to inhibit microbe growth in an anatomical region surrounding the catheter. The desired anti-microbial properties may be provided by an anti-microbial layer, anti-microbial materials dispersed within the material from which components of the catheters are constructed, or a combination of anti-microbial layers and embedded anti-microbial materials. In some arrangements, one or more portions of the catheter may be bio-absorbable.

14. 发明授权

US07780638B1 Catheter for uniform delivery of medication 有权
标题翻译：导管统一服药
公开(公告)号：US07780638B1
公开(公告)日：2010-08-24
申请号：US10031913
申请日：2000-07-19
申请人： Jose Castillo Deniega , Roger Massengale , Kenneth W. Rake
发明人： Jose Castillo Deniega , Roger Massengale , Kenneth W. Rake
IPC分类号： A61M5/00 , A61M25/00
CPC分类号： A61M25/0074 , A61M25/00 , A61M25/0023 , A61M25/0043 , A61M25/0068 , A61M25/0069 , A61M25/007 , A61M2025/0037 , A61M2025/0039 , A61M2025/0057 , A61M2025/0073
摘要： The present invention provides a catheter for the delivery of fluid medication across an anatomical region. In accordance with one embodiment, the catheter comprises an elongated tube with a plurality of exit holes along an infusion section of the catheter, and an elongated flexible porous member residing within the tube and forming an annular space between the tube and the member. In accordance with other embodiments, the catheter includes a tube having a plurality of exit holes in a side wall of the tube. The exit holes may combine to form a flow-restricting orifice of the catheter. Advantageously, fluid within the catheter flows through all of the exit holes, resulting in uniform distribution of fluid within an anatomical region. In one particular embodiment, the catheter comprises a tube having elongated exit slots therein. In accordance with other embodiments, the catheter includes an elongated tubular member made of a porous membrane. The porous membrane is configured so that a fluid introduced into an open end of the tubular member will flow through side walls of the tubular member at a substantially uniform rate along a length of the tubular member. In accordance with other embodiments, the catheter includes an elongated “weeping” tubular coil spring attached to an end of, or enclosed within, a tube. Fluid within the spring and greater than or equal to a threshold pressure advantageously flows radially outward between the spring coils. Advantageously, the fluid is dispensed substantially uniformly throughout a length of the spring.
摘要翻译：本发明提供一种用于在解剖区域上输送流体药物的导管。根据一个实施例，导管包括细长管，其具有沿着导管的输注部分的多个出口孔，以及驻留在管内并在管与构件之间形成环形空间的细长柔性多孔构件。根据其他实施例，导管包括管，其在管的侧壁中具有多个出口孔。出口孔可以组合形成导管的限流孔。有利地，导管内的流体流过所有出口孔，导致流体在解剖区域内的均匀分布。在一个具体实施例中，导管包括其中具有细长出口槽的管。根据其他实施例，导管包括由多孔膜制成的细长管状构件。多孔膜被构造成使得引入到管状构件的开口端的流体将沿着管状构件的长度以基本均匀的速率流过管状构件的侧壁。根据其他实施例，导管包括连接到管的端部或封闭在管内的细长的“哭泣”管状螺旋弹簧。弹簧内的流体大于或等于阈值压力有利地在弹簧圈之间径向向外流动。有利地，流体在弹簧的整个长度上基本均匀地分配。

15. 发明申请

US20090250124A1 PRESSURE REGULATOR 有权
标题翻译：压力调节器
公开(公告)号：US20090250124A1
公开(公告)日：2009-10-08
申请号：US12484988
申请日：2009-06-15
申请人： Roger Massengale , Stanley E. Fry , Charles J. McPhee
发明人： Roger Massengale , Stanley E. Fry , Charles J. McPhee
IPC分类号： F16K1/00
CPC分类号： G05D16/0647 , Y10S137/903 , Y10T137/0379 , Y10T137/0396 , Y10T137/0497 , Y10T137/7825 , Y10T137/7871 , Y10T137/7922 , Y10T137/8225 , Y10T137/8326
摘要： A variable device for regulating the outlet pressure of a fluid from a valve body, includes a pressure-sensing chamber having a wall formed by a resilient self-restoring diaphragm which is responsive to pressure in the chamber. A valve element connected to the diaphragm controls flow into the chamber. Increased pressure in the chamber decreases the flow into the chamber and decreasing pressure increases flow whereby fluid flow out from the chamber is maintained at a desired pressure. The outlet pressure is adjusted by deflecting the diaphragm in a direction to open the valve while permitting a section of the diaphragm connected to the valve member to remain responsive to the pressure in the chamber. An adjustment cover is provided to adjustably deflect the diaphragm and includes a catch mechanism to allow adjustment of the fluid outlet pressures and also retain the device at a desired value. An indicator arrangement may be provided to visually indicate the fluid outlet pressure.
摘要翻译：用于调节来自阀体的流体的出口压力的可变装置包括压力感测室，该压力感测室具有由响应腔室中的压力的弹性自恢复隔膜形成的壁。连接到隔膜的阀元件控制流入腔室。室中增加的压力降低了进入室的流量，并且减小的压力增加了流量，从而从腔室流出的流体保持在期望的压力。出口压力通过使膜片沿打开阀的方向偏转来调节，同时允许连接到阀构件的隔膜的一部分保持对腔室中的压力的响应。提供调节盖以可调节地偏转隔膜并且包括捕获机构以允许调节流体出口压力并且还将装置保持在期望值。可以提供指示器布置以在视觉上指示流体出口压力。

16. 发明申请

US20070017580A1 Pressure regulator 有权
公开(公告)号：US20070017580A1
公开(公告)日：2007-01-25
申请号：US11527848
申请日：2006-09-27
申请人： Roger Massengale , Stanley Fry , Charles McPhee
发明人： Roger Massengale , Stanley Fry , Charles McPhee
IPC分类号： F16K37/00
CPC分类号： G05D16/0647 , Y10S137/903 , Y10T137/0379 , Y10T137/0396 , Y10T137/0497 , Y10T137/7825 , Y10T137/7871 , Y10T137/7922 , Y10T137/8225 , Y10T137/8326
摘要： A variable device for regulating the outlet pressure of a fluid from a valve body, includes a pressure-sensing chamber having a wall formed by a resilient self-restoring diaphragm which is responsive to pressure in the chamber. A valve element connected to the diaphragm controls flow into the chamber. Increased pressure in the chamber decreases the flow into the chamber and decreasing pressure increases flow whereby fluid flow out from the chamber is maintained at a desired pressure. The outlet pressure is adjusted by deflecting the diaphragm in a direction to open the valve while permitting a section of the diaphragm connected to the valve member to remain responsive to the pressure in the chamber. An adjustment cover is provided to adjustably deflect the diaphragm and includes a catch mechanism to allow adjustment of the fluid outlet pressures and also retain the device at a desired value. An indicator arrangement may be provided to visually indicate the fluid outlet pressure.

17. 发明申请

US20060149192A1 Catheter for uniform delivery of medication 有权
标题翻译：导管统一服药
公开(公告)号：US20060149192A1
公开(公告)日：2006-07-06
申请号：US11364767
申请日：2006-02-28
申请人： Jose Deniega , Roger Massengale , Kenneth Rake
发明人： Jose Deniega , Roger Massengale , Kenneth Rake
IPC分类号： A61M25/00
CPC分类号： A61M25/0074 , A61M25/00 , A61M25/0023 , A61M25/0043 , A61M25/0068 , A61M25/0069 , A61M25/007 , A61M2025/0037 , A61M2025/0039 , A61M2025/0057 , A61M2025/0073
摘要： The present invention provides a catheter for the delivery of fluid medication across an anatomical region. In accordance with one embodiment, the catheter comprises an elongated tube with a plurality of exit holes along an infusion section of the catheter, and an elongated flexible porous member residing within the tube and forming an annular space between the tube and the member. In accordance with other embodiments, the catheter includes a tube having a plurality of exit holes in a side wall of the tube. The exit holes may combine to form a flow-restricting orifice of the catheter. In one particular embodiment, the catheter comprises a tube having elongated exit slots therein. In accordance with other embodiments, the catheter includes an elongated tubular member made of a porous membrane. In accordance with other embodiments, the catheter includes an elongated “weeping” tubular coil spring attached to an end of, or enclosed within, a tube.
摘要翻译：本发明提供一种用于在解剖区域上输送流体药物的导管。根据一个实施例，导管包括细长管，其具有沿着导管的输注部分的多个出口孔，以及驻留在管内并在管与构件之间形成环形空间的细长柔性多孔构件。根据其他实施例，导管包括管，其在管的侧壁中具有多个出口孔。出口孔可以组合形成导管的限流孔。在一个具体实施例中，导管包括其中具有细长出口槽的管。根据其他实施例，导管包括由多孔膜制成的细长管状构件。根据其他实施例，导管包括连接到管的端部或封闭在管内的细长的“哭泣”管状螺旋弹簧。

18. 发明申请

US20060135941A1 Anti-microbial catheter 有权
公开(公告)号：US20060135941A1
公开(公告)日：2006-06-22
申请号：US11216534
申请日：2005-08-31
申请人： James Porto , Jose Deniega , Roger Massengale , Kenneth Rake , Kevin Forrest , Mark Siminuk , Lois Rake
发明人： James Porto , Jose Deniega , Roger Massengale , Kenneth Rake , Kevin Forrest , Mark Siminuk , Lois Rake
IPC分类号： A61M31/00
CPC分类号： A61L27/54 , A61L29/16 , A61L2300/104 , A61L2300/404 , A61M25/0045 , A61M25/0069 , A61M25/007 , A61M25/0071 , A61M2025/0056 , A61M2025/0057
摘要： A catheter having features configured to provide a substantially uniform flow rate of a fluid exiting the catheter and also exhibits anti-microbial properties. The uniform flow rate features may include one or more of a flow restricting membrane or flow restricting component within an infusion section of the catheter. In other arrangements, exit holes defining the infusion section of the catheter may be configured to provide the desired uniform flow rate over the length of the infusion section. Furthermore, the catheter also includes anti-microbial properties to inhibit the growth of microbes on or within the catheter and, preferably, to inhibit microbe growth in an anatomical region surrounding the catheter. The desired anti-microbial properties may be provided by an anti-microbial layer, anti-microbial materials dispersed within the material from which components of the catheters are constructed, or a combination of anti-microbial layers and embedded anti-microbial materials. In some arrangements, one or more portions of the catheter may be bio-absorbable.

19. 发明申请

US20060048822A1 Pressure regulator 有权
公开(公告)号：US20060048822A1
公开(公告)日：2006-03-09
申请号：US11217104
申请日：2005-08-31
申请人： Roger Massengale , Stanley Fry , Charles McPhee
发明人： Roger Massengale , Stanley Fry , Charles McPhee
IPC分类号： F16K37/00
CPC分类号： G05D16/0647 , Y10S137/903 , Y10T137/0379 , Y10T137/0396 , Y10T137/0497 , Y10T137/7825 , Y10T137/7871 , Y10T137/7922 , Y10T137/8225 , Y10T137/8326
摘要： A variable device for regulating the outlet pressure of a fluid from a valve body, includes a pressure-sensing chamber having a wall formed by a resilient self-restoring diaphragm which is responsive to pressure in the chamber. A valve element connected to the diaphragm controls flow into the chamber. Increased pressure in the chamber decreases the flow into the chamber and decreasing pressure increases flow whereby fluid flow out from the chamber is maintained at a desired pressure. The outlet pressure is adjusted by deflecting the diaphragm in a direction to open the valve while permitting a section of the diaphragm connected to the valve member to remain responsive to the pressure in the chamber. An adjustment cover is provided to adjustably deflect the diaphragm and includes a catch mechanism to allow adjustment of the fluid outlet pressures and also retain the device at a desired value. An indicator arrangement may be provided to visually indicate the fluid outlet pressure.

20. 发明申请

US20050106225A1 Fluid medication delivery device 有权
标题翻译：流体药物输送装置
公开(公告)号：US20050106225A1
公开(公告)日：2005-05-19
申请号：US10942735
申请日：2004-09-16
申请人： Roger Massengale , Kevin Forrest , Bill Porter , Donald Earhart , Alan Dine
发明人： Roger Massengale , Kevin Forrest , Bill Porter , Donald Earhart , Alan Dine
IPC分类号： A61F13/00 , A61K9/22 , A61K9/70 , A61K31/00 , A61L15/00 , A61L15/22 , A61L15/42 , A61M35/00 , A61L15/16
CPC分类号： A61M35/00 , A61F2013/00651 , A61L15/22 , A61L15/42
摘要： A fluid delivery device for transdermal delivery of a fluid to a patient. The device comprises an envelope that may be applied to a patient's skin. The envelope comprises at least one diffusion layer coupled to at least one impermeable layer such that at least a chamber is defined therebetween. Other embodiments include internal diffusion layers, and thus possess additional chambers, as well. In one arrangement, an adhesive boundary layer permits the device to be removably secured to a patient and inhibits radial migration of fluid beyond the periphery of the device. In another arrangement, preferably, an anti-microbial layer is provided to inhibit the growth of microorganisms.
摘要翻译：用于将流体透皮递送至患者的流体递送装置。该装置包括可应用于患者皮肤的信封。该包络线包括至少一个与至少一个不可渗透层相连的扩散层，使得至少一个室被限定在其间。其他实施方案也包括内部扩散层，因此也具有另外的室。在一种布置中，粘合剂边界层允许该装置可移除地固定到患者身上并且抑制流体径向迁移超出该装置的周边。在另一种布置中，优选地，提供抗微生物层以抑制微生物的生长。

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