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11. 发明授权

US6107158A Method of manufacturing a trench structure in a semiconductor substrate 失效
标题翻译：在半导体衬底中制造沟槽结构的方法
公开(公告)号：US6107158A
公开(公告)日：2000-08-22
申请号：US47959
申请日：1998-03-25
申请人： Jie Zheng , Calvin Todd Gabriel , Suzanne Monsees
发明人： Jie Zheng , Calvin Todd Gabriel , Suzanne Monsees
IPC分类号： H01L21/762 , H01L21/306
CPC分类号： H01L21/76232 , Y10S438/978
摘要： A shallow trench isolation structure and method for forming such structure. In one embodiment, the semiconductor device isolating structure of the present invention includes a trench formed into a semiconductor substrate. A cross-section of the trench has a first sidewall sloping inwardly towards the center of a substantially planar bottom surface, and a second sidewall sloping inwardly towards the center of the substantially planar bottom surface. Additionally, a cross section of the trench has a first rounded bottom trench corner at an interface of the first sidewall and the substantially planar bottom surface, and a second rounded bottom trench corner at an interface of the second sidewall and the substantially planar bottom surface. Furthermore, the trench of the present invention has a first rounded upper trench corner at the interface of the first sidewall and the top surface of the semiconductor substrate, and a second rounded upper trench corner at the interface of the second sidewall and the top surface of the semiconductor substrate. Thus, the trench of the present invention does not have micro-trenches formed into the bottom surface thereof. Additionally, the present invention does not have the sharp upper and bottom corners found in conventional trenches formed using a shallow trench isolation method. The present invention also provides a method to eliminate deleterious micromasking and spike formation.
摘要翻译：浅沟槽隔离结构及其形成方法。在一个实施例中，本发明的半导体器件隔离结构包括形成半导体衬底的沟槽。沟槽的横截面具有朝向基本上平坦的底表面的中心向内倾斜的第一侧壁和朝向基本平坦的底表面的中心向内倾斜的第二侧壁。此外，沟槽的横截面具有在第一侧壁和基本上平坦的底表面的界面处的第一圆形底部沟槽角以及在第二侧壁和基本上平坦的底表面的界面处的第二圆形底部沟槽拐角。此外，本发明的沟槽在第一侧壁和半导体衬底的顶表面的界面处具有第一圆形上沟槽角，以及在第二侧壁和第二侧壁的顶表面的界面处的第二圆形上沟槽角半导体衬底。因此，本发明的沟槽不具有形成在其底表面中的微沟槽。此外，本发明不具有使用浅沟槽隔离方法形成的常规沟槽中发现的尖锐的上部和下部角落。本发明还提供消除有害的微掩模和尖峰形成的方法。

12. 发明授权

US09695549B2 Detoxifying and recycling of washing solution used in pretreatment of lignocellulose-containing materials 有权
公开(公告)号：US09695549B2
公开(公告)日：2017-07-04
申请号：US12203511
申请日：2008-09-03
申请人： Haiyu Ren , Hong Zhi Huang , Jie Zheng
发明人： Haiyu Ren , Hong Zhi Huang , Jie Zheng
IPC分类号： D21C11/00 , D21C5/00 , C12P19/02 , C12P7/10 , D21C1/00 , D21C9/02
CPC分类号： D21C11/005 , C12P7/10 , C12P19/02 , C12P2201/00 , D21C1/00 , D21C5/005 , D21C9/02 , D21C11/0007 , D21C11/0042 , Y02E50/16
摘要： The invention relates to a process of detoxifying pretreated lignocellulose-containing material comprising washing the pretreated lignocellulose-containing material in a washing solution and treating the used washing solution to remove an enzyme inhibitor and/or an inhibitor of a fermenting organism before recycling the used washing solution.

13. 发明授权

US08716243B2 Methods of effecting Wnt signaling through Dkk structural analysis 有权
标题翻译：通过Dkk结构分析实现Wnt信号传导的方法
公开(公告)号：US08716243B2
公开(公告)日：2014-05-06
申请号：US12454758
申请日：2009-05-22
申请人： Jie Zheng
发明人： Jie Zheng
IPC分类号： A61K38/16 , A61K38/00 , A61P19/08 , A61P19/10
CPC分类号： C07K14/705 , A61K31/00 , A61K38/00 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K16/32 , G01N33/5041 , G01N33/68 , G01N2333/495 , G01N2333/705 , A61K2300/00
摘要： Compositions and methods related to Wnt signaling regulation by Dickkopf (Dkk) polypeptides and Wnt-related diseases are disclosed. For example, compounds that bind a Dkk or LRP polypeptide are disclosed. Compounds that disrupt binding of a Dkk polypeptide to an LRP polypeptide are also disclosed. Methods for using the described compounds and compositions are also disclosed.
摘要翻译：公开了与Dickkopf（Dkk）多肽和Wnt相关疾病的Wnt信号调节有关的组合物和方法。例如，公开了结合Dkk或LRP多肽的化合物。还公开了破坏Dkk多肽与LRP多肽的结合的化合物。还公开了使用所述化合物和组合物的方法。

14. 发明授权

US08429651B2 Enablement and acceleration of live and near-live migration of virtual machines and their associated storage across networks 有权
标题翻译：启用和加速虚拟机及其相关存储跨网络的实时和近实时迁移
公开(公告)号：US08429651B2
公开(公告)日：2013-04-23
申请号：US12690552
申请日：2010-01-20
申请人： Sean Donnellan , Chitra Dorai , Anees A. Shaikh , Kunwadee Sripanidkulchai , Jie Zheng
发明人： Sean Donnellan , Chitra Dorai , Anees A. Shaikh , Kunwadee Sripanidkulchai , Jie Zheng
IPC分类号： G06F9/455 , G06F9/46
CPC分类号： G06F9/45558 , G06F2009/4557
摘要： A virtual machine is migrated between a source cloud and a destination cloud. A temporary storage is mounted to a partition management firmware of the source cloud and to a partition management firmware of the destination cloud. A first storage location migration migrates the virtual machine from the source cloud to the at least one temporary storage. A second storage location migration migrates the virtual machine from the at least one temporary storage to final destination storage of the destination cloud. The temporary storage is then unmounted from the partition management firmware of the source cloud and from the partition management firmware of the destination cloud.
摘要翻译：虚拟机在源云和目标云之间迁移。临时存储装载到源云的分区管理固件和目的地云的分区管理固件。第一个存储位置迁移将虚拟机从源云迁移到至少一个临时存储。第二个存储位置迁移将虚拟机从至少一个临时存储迁移到目标云的最终目标存储。然后从源云的分区管理固件和目标云的分区管理固件卸载临时存储。

15. 发明申请

US20120221744A1 Migrating Virtual Machines with Adaptive Compression 有权
标题翻译：使用自适应压缩迁移虚拟机
公开(公告)号：US20120221744A1
公开(公告)日：2012-08-30
申请号：US13035365
申请日：2011-02-25
申请人： Patrick B. Heywood , Sambit Sahu , Kunwadee Sripanidkulchai , Jie Zheng
发明人： Patrick B. Heywood , Sambit Sahu , Kunwadee Sripanidkulchai , Jie Zheng
IPC分类号： G06F15/16
CPC分类号： G06F9/4862
摘要： A method, data processing system, and computer program product for managing images. A processor unit divides an image for a virtual machine into blocks. The processor unit determines whether to compress the blocks prior to transmitting the blocks to a destination for the image. In response to a determination to compress the blocks, the processor unit compresses the blocks to form a compressed set of blocks. The processor unit sends the compressed set of blocks and any uncompressed blocks remaining in the blocks to the destination for the image.
摘要翻译：一种用于管理图像的方法，数据处理系统和计算机程序产品。处理器单元将虚拟机的图像划分为块。处理器单元在将块发送到图像的目的地之前确定是否压缩块。响应于压缩块的确定，处理器单元压缩块以形成压缩的块集合。处理器单元将压缩的块集合和块中剩余的任何未压缩块发送到图像的目的地。

16. 发明申请

US20120178697A9 Compositions and methods for the inhibition of dishevelled proteins 审中-公开
标题翻译：用于抑制杂乱蛋白质的组合物和方法
公开(公告)号：US20120178697A9
公开(公告)日：2012-07-12
申请号：US11097518
申请日：2005-04-01
申请人： Jie Zheng , Jufang Shan , Dianqing Wu
发明人： Jie Zheng , Jufang Shan , Dianqing Wu
IPC分类号： A61K31/16 , A61K31/195 , A61K31/20 , A61K31/235 , A61K31/351 , A61K31/381 , A61K31/4025 , A61K31/41 , A61K31/415 , A61K31/50 , A61K31/505 , A61K31/519 , A61K31/53 , A61K31/5377 , A61K31/70 , A61K38/02 , A61K38/16 , A61P3/00 , A61P35/00 , A61P5/00 , C40B20/08 , C40B30/02 , C40B30/04 , A61K31/165
CPC分类号： A61K31/00 , A61K31/164 , C07K1/00 , C40B30/02
摘要： The Wnt signaling pathways are involved in embryo development as well as in tumorigenesis. Dishevelled (Dvl) tranduces Wnt signals from the receptor Frizzled (Fz) to downstream components in canonical and non-canonical Wnt signaling pathways, and the Dvl PDZ domain plays an essential role in both pathways, and the Dvl PDZ domain binds directly to Fz receptors. In the present invention using NMR-assisted virtual ligand screening, several compounds were identified and were found to bind to the Dvl PDZ domain. Molecular dynamics simulation was used to analyze the binding between the PDZ domain and these compounds in detail. These compounds provide a basis for rational design of high-affinity inhibitors of the PDZ domain, which can block Wnt signaling by interrupting the Fz-Dvl interaction.
摘要翻译： Wnt信号通路参与胚胎发育以及肿瘤发生。不规则（Dvl）将来自受体卷曲（Fz）的Wnt信号转导到规范和非规范Wnt信号通路中的下游组分，并且Dv1 PDZ结构域在两个途径中起重要作用，并且Dv1 PDZ结构域直接结合Fz受体。在使用NMR-辅助虚拟配体筛选的本发明中，鉴定了几种化合物，并且发现它们与Dvl PDZ结构域结合。分子动力学模拟用于详细分析PDZ结构域与这些化合物的结合。这些化合物为PDZ结构域的高亲和力抑制剂的合理设计提供了基础，可以通过中断Fz-Dv1相互作用来阻断Wnt信号。

17. 发明授权

US08105847B2 Nano-sized optical fluorescence labels and uses thereof 有权
标题翻译：纳米尺寸的光学荧光标记及其用途
公开(公告)号：US08105847B2
公开(公告)日：2012-01-31
申请号：US12571865
申请日：2009-10-01
申请人： Robert Martin Dickson , Jie Zheng
发明人： Robert Martin Dickson , Jie Zheng
IPC分类号： G01N33/553
CPC分类号： B82Y15/00 , G01N33/582 , G01N33/588 , Y10S436/805
摘要： A composition is disclosed which is capable of being used for detection, comprising an encapsulated noble metal nanocluster. Methods for preparing the encapsulated noble metal nanoclusters, and methods of using the encapsulated noble metal nanoclusters are also disclosed. The noble metal nanoclusters are preferably encapsulated by a dendrimer or a peptide. The encapsulated noble metal nanoclusters have a characteristic spectral emission, wherein said spectral emission is varied by controlling the nature of the encapsulating material, such as by controlling the size of the nanocluster and/or the generation of the dendrimer, and wherein said emission is used to provide information about a biological state.
摘要翻译：公开了能够用于检测的组合物，其包含包封的贵金属纳米簇。还公开了制备包封的贵金属纳米簇的方法，以及使用包封的贵金属纳米团簇的方法。贵金属纳米团簇优选被树枝状聚合物或肽包封。封装的贵金属纳米团簇具有特征光谱发射，其中所述光谱发射通过控制封装材料的性质而变化，例如通过控制纳米簇的尺寸和/或树枝状聚合物的产生，并且其中使用所述发射提供有关生物状态的信息。

18. 发明申请

US20110179415A1 ENABLEMENT AND ACCELERATION OF LIVE AND NEAR-LIVE MIGRATION OF VIRTUAL MACHINES AND THEIR ASSOCIATED STORAGE ACROSS NETWORKS 有权
标题翻译：虚拟机的活动和近期移动的促成和加速及其相关网络的相关存储
公开(公告)号：US20110179415A1
公开(公告)日：2011-07-21
申请号：US12690552
申请日：2010-01-20
申请人： Sean Donnellan , Chitra Dorai , Anees A. Shaikh , Kunwadee Sripanidkulchai , Jie Zheng
发明人： Sean Donnellan , Chitra Dorai , Anees A. Shaikh , Kunwadee Sripanidkulchai , Jie Zheng
IPC分类号： G06F9/455 , G06F15/16 , G06F12/02 , G06F21/20
CPC分类号： G06F9/45558 , G06F2009/4557
摘要： A virtual machine is migrated between a source cloud and a destination cloud. A temporary storage is mounted to a partition management firmware of the source cloud and to a partition management firmware of the destination cloud. A first storage location migration migrates the virtual machine from the source cloud to the at least one temporary storage. A second storage location migration migrates the virtual machine from the at least one temporary storage to final destination storage of the destination cloud. The temporary storage is then unmounted from the partition management firmware of the source cloud and from the partition management firmware of the destination cloud.
摘要翻译：虚拟机在源云和目标云之间迁移。临时存储装载到源云的分区管理固件和目的地云的分区管理固件。第一个存储位置迁移将虚拟机从源云迁移到至少一个临时存储。第二个存储位置迁移将虚拟机从至少一个临时存储迁移到目标云的最终目标存储。然后从源云的分区管理固件和目标云的分区管理固件卸载临时存储。

19. 发明授权

US06602742B2 Supercapacitor and a method of manufacturing such a supercapacitor 失效
公开(公告)号：US06602742B2
公开(公告)日：2003-08-05
申请号：US09986569
申请日：2001-11-09
申请人： Yurii Maletin , Natalie Strizhakova , Sergey Kozachkov , Antonina Mironova , Sergey Podmogilny , Valerii Danilin , Julia Kolotilova , Volodymyz Izotov , Jan Cederström , Sergey Gordeev Konstantinovich , Julia Kukushkina Aleksandrovna , Vasilii Sokolov Vasilevitj , Alexander Kravehik Efimovitj , Anti Perkson , Mati Arulepp , Jaan Leis , Clarence L. Wallace , Jie Zheng
发明人： Yurii Maletin , Natalie Strizhakova , Sergey Kozachkov , Antonina Mironova , Sergey Podmogilny , Valerii Danilin , Julia Kolotilova , Volodymyz Izotov , Jan Cederström , Sergey Gordeev Konstantinovich , Julia Kukushkina Aleksandrovna , Vasilii Sokolov Vasilevitj , Alexander Kravehik Efimovitj , Anti Perkson , Mati Arulepp , Jaan Leis , Clarence L. Wallace , Jie Zheng
IPC分类号： H01L21335
CPC分类号： H01G11/34 , H01G11/24 , H01G11/86 , H01M2/1606 , H01M4/583 , H01M4/623 , Y02E60/13 , Y10T29/417
摘要： An electric double layer capacitor including at least one pair of polarizable electrodes connected to current collectors, a separator made of ion-permeable but electron-insulating material interposed between the electrodes in each pair of electrodes, and a liquid electrolyte. According to the invention the electrodes include a layer of carbon particles having a narrow distribution of nanopores therein, the pore sizes of the nanopores being adapted to fit the ion sizes of the electrolyte. The invention also relates to a method of manufacturing such a supercapacitor.

20. 发明授权

US6044030A FIFO unit with single pointer 失效
标题翻译：具有单指针的FIFO单元
公开(公告)号：US6044030A
公开(公告)日：2000-03-28
申请号：US217428
申请日：1998-12-21
申请人： Jie Zheng , William Webster Kolb , Hartmut Karl Habben
发明人： Jie Zheng , William Webster Kolb , Hartmut Karl Habben
IPC分类号： G11C7/00 , G06F5/06 , G06F5/10 , H04L13/08
CPC分类号： G06F5/10
摘要： A FIFO unit for buffering serial communications includes a register and a unit for maintaining a single pointer. The single pointer functions as an IN pointer during writes and an OUT pointer during reads. The same circuitry maintains the pointer for both reads and writes to the FIFO. This circuitry preferably includes a single counter. If an error occurs during reading, the single pointer can be reinitialized and reading restarted, without loss of data. The register is not erased until reading is complete.
摘要翻译：用于缓冲串行通信的FIFO单元包括寄存器和用于维持单个指针的单元。单个指针在写入期间用作IN指针，在读取期间用作OUT指针。相同的电路保持用于读取和写入FIFO的指针。该电路优选地包括单个计数器。如果在读取期间发生错误，则可以重新初始化单个指针并重新启动读取，而不会丢失数据。读取完成之前，寄存器不会被清除。

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