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    • 17. 发明授权
    • Acoustic ejection of fluids using large F-number focusing elements
    • 使用大的F数量聚焦元件的流体声弹射
    • US06416164B1
    • 2002-07-09
    • US09910690
    • 2001-07-20
    • Richard G. StearnsRichard N. Ellson
    • Richard G. StearnsRichard N. Ellson
    • B41J204
    • B41J2/14008
    • The present invention provides a method and device for the acoustic ejection of fluid droplets from fluid-containing reservoirs using focusing means having an F-number greater than approximately 2. The droplets are ejected toward designated sites on a substrate surface for deposition thereon. In one embodiment, the device is comprised of: a plurality of reservoirs each adapted to contain a fluid; an ejector comprising a means for generating acoustic radiation and a large F-numbered means for focusing the acoustic radiation at a focal point near the fluid surface in each of the reservoirs; and a means for positioning the ejector in acoustically coupled relationship to each of the reservoirs. The invention is useful in a number of contexts, particularly in the preparation of biomolecular arrays.
    • 本发明提供一种用于使用具有大于约2的F数的聚焦装置从含有流体的储存器弹出流体液滴的方法和装置。液滴朝向衬底表面上的指定位置喷射以沉积在其上。 在一个实施例中,该装置包括:多个储存器,每个储存器适于容纳流体; 喷射器,其包括用于产生声辐射的装置和用于将声辐射聚焦在每个储存器中的流体表面附近的焦点处的大的F编号装置; 以及用于将喷射器定位成与每个储存器的声耦合关系的装置。 本发明在许多上下文中是有用的,特别是在生物分子阵列的制备中。
    • 19. 发明授权
    • Methods and apparatus for robust decoding of glyph address carpets
    • 用于字形地址地毯的鲁棒解码的方法和装置
    • US06208771B1
    • 2001-03-27
    • US09144518
    • 1998-08-31
    • David A. JaredL. Noah FloresDavid L. HechtRichard G. StearnsKenneth H. P. Chang
    • David A. JaredL. Noah FloresDavid L. HechtRichard G. StearnsKenneth H. P. Chang
    • G06K954
    • G06K19/06037G06K7/14
    • A captured image includes a portion of a set of two-dimensional address codes. The portion of address codes can be decoded to determine a discrete pointer uniquely defining the portion. The captured image is first processed to determine the orientation of the portion, and then decoded based on the orientation to determine the discrete pointer. To determine the orientation of the portion, the portion is first analyzed to determine values at discrete locations within the portion. The values at each location form a matrix of binary data. The values of the matrix are then correlated to determine an orientation of the captured portion of two dimensional address codes. After determining the orientation of the portion, the values can be further analyzed to determine a discrete pointer that identifies the location of the portion within the address space defined by the two-dimensional address codes.
    • 捕获的图像包括一组二维地址码的一部分。 地址码的部分可被解码以确定唯一地限定该部分的离散指示器。 首先处理捕获的图像以确定该部分的取向,然后基于取向解码以确定离散指针。 为了确定部分的方向,首先分析该部分以确定该部分内的离散位置处的值。 每个位置的值形成二进制数据矩阵。 然后将矩阵的值相关以确定二维地址码的捕获部分的取向。 在确定该部分的方向之后,可以进一步分析这些值以确定用于标识由二维地址码定义的地址空间内部分的位置的离散指针。
    • 20. 发明授权
    • Self-clocking glyph code having composite glyphs for distributively
encoding multi-bit digital values
    • 具有用于分布式编码多位数字值的复合字形的自时钟字形码
    • US6000613A
    • 1999-12-14
    • US186212
    • 1994-01-25
    • David L. HechtRichard G. StearnsL. Noah Flores
    • David L. HechtRichard G. StearnsL. Noah Flores
    • G06K1/12G06K9/18G06K19/06G06F7/10
    • G06K7/143G06K1/121G06K19/06037G06K9/18
    • A self-clocking glyph code is provided for encoding n-bit long digital values (where n>1) in a logically ordered sequence of composite glyphs that are written, printed, or otherwise recorded on a hardcopy recording medium in accordance with a predetermined spatial formatting rule. As used herein, a "composite glyph" is a graphical symbol that has a plurality of predefined, substantially orthogonal, graphical characteristics; each of which is capable of assuming any one of a plurality of predefined graphical states. An n-bit long digital value is distributively encoded in a glyph of this type by decomposing its n-bits, prior to or during the encoding, into a plurality of shorter, ordered, non-overlapping bit strings. The digital values of these bit strings, in turn, are encoded in the states of respective graphical characteristics of the composite glyph in a predetermined logical order, thereby preserving the logical ordering of the bit strings.
    • 提供了一种自定时字形码,用于根据预定的空间来编写,打印或以其他方式记录在硬拷贝记录介质上的合成字形的逻辑有序序列中的n位长数字值(其中n> 1) 格式规则。 如本文所使用的,“复合字形”是具有多个预定义的,基本正交的图形特征的图形符号; 其中的每一个都能够呈现多个预定图形状态中的任何一个。 n位长数字值通过在编码之前或期间将其n位分解成多个较短的,有序的,不重叠的位串来分散编码在这种类型的字形中。 这些位串的数字值依次以预定的逻辑顺序被编码在复合字形的相应图形特征的状态中,从而保留位串的逻辑顺序。