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11. 发明授权

US07632919B2 Polystyrene binding peptides and methods of use 有权
标题翻译：聚苯乙烯结合肽及其使用方法
公开(公告)号：US07632919B2
公开(公告)日：2009-12-15
申请号：US11607673
申请日：2006-12-01
申请人： Scott D. Cunningham , David J. Lowe , John P. O'Brien , Hong Wang , Antoinette E. Wilkins
发明人： Scott D. Cunningham , David J. Lowe , John P. O'Brien , Hong Wang , Antoinette E. Wilkins
IPC分类号： A61K38/10 , A61K8/64 , C07K5/04
CPC分类号： C07K7/08 , C07K7/06 , C07K14/001 , C07K14/47 , Y10T156/10
摘要： Combinatorially generated peptides are provided that have binding affinity for polystyrene (PS). The peptides may be used to deliver benefit agents to various PS surfaces.
摘要翻译：提供了对聚苯乙烯（PS）具有结合亲和力的组合产生的肽。肽可以用于将有益剂递送到各种PS表面。

12. 发明申请

US20080182307A1 METHOD FOR PREPARING PARA-HYDROXYSTYRENE BY BIOCATALYTIC DECARBOXYLATION OF PARA-HYDROXYCINNAMIC ACID IN A BIPHASIC REACTION MEDIUM 审中-公开
标题翻译：通过生物反应脱羧反应在双相反应介质中制备对羟基苯乙烯的方法
公开(公告)号：US20080182307A1
公开(公告)日：2008-07-31
申请号：US12058986
申请日：2008-03-31
申请人： ARIE BEN-BASSAT , Sharon L. Haynie , David J. Lowe , Lisa L. Huang
发明人： ARIE BEN-BASSAT , Sharon L. Haynie , David J. Lowe , Lisa L. Huang
IPC分类号： C12P7/22
CPC分类号： C12P7/22 , C12P7/42
摘要： A biocatalytic method for preparing para-hydroxystyrene from para-hydroxycinnamic acid is described. The method uses an enzyme source having para-hydroxycinnamic acid decarboxylase activity to catalyze the decarboxylation of para-hydroxycinnamic acid in a biphasic reaction medium to produce para-hydroxystyrene, which is extracted into the organic phase of the biphasic reaction medium. The method results in a high yield of para-hydroxystyrene due to the decreased exposure of the enzyme source to the inhibitory product. The product is readily recovered from the extractant, or may be chemically derivatized directly in the extractant before recovery.
摘要翻译：描述了由对羟基肉桂酸制备对羟基苯乙烯的生物催化方法。该方法使用具有对羟基肉桂酸脱羧酶活性的酶源来催化双相反应介质中对羟基肉桂酸的脱羧作用，产生对羟基苯乙烯，将其提取到双相反应介质的有机相中。该方法由于酶源暴露于抑制产物而导致对羟基苯乙烯的高产率。该产物容易从萃取剂中回收，或者可以在回收之前在萃取剂中直接化学衍生化。

13. 发明授权

US07166460B2 Product removal process for use in a biofermentation system 失效
标题翻译：用于生物发酵系统的产品去除过程
公开(公告)号：US07166460B2
公开(公告)日：2007-01-23
申请号：US10860221
申请日：2004-06-03
申请人： Antoinette E. Wilkins , David J. Lowe
发明人： Antoinette E. Wilkins , David J. Lowe
IPC分类号： C12M3/00 , B01D15/08
CPC分类号： C12M47/12 , B01D15/1814 , B01D15/426 , C12M29/02 , C12M33/14 , C12M47/10 , C12N1/38 , C12P7/18
摘要： This invention relates to a bioprocess engineering solution for a product removal process for use in a biofermentation. The invention discloses a process for withdrawing an aliquot of broth from a biofermentation vessel during at least a portion of the biofermentation, removing biocatalyst and water, chromatographically separating biofermentation products from the withdrawn broth using water as an eluent, and returning the remaining components of the broth back to the biofermentation vessel. Process chromatography permits highly selective separation of the target molecule, preventing feedback inhibition of the biofermentation.
摘要翻译：本发明涉及用于生物发酵的产品去除方法的生物工艺工程解决方案。本发明公开了一种在至少一部分生物发酵过程中从生物发酵容器中取出等份的肉汤的方法，除去生物催化剂和水，使用水作为洗脱剂，使生物发酵产物与取出的肉汤色谱分离，并返回剩余组分肉汤回到生物发酵罐。过程色谱法允许目标分子的高度选择性分离，防止反应抑制生物发酵。

14. 发明授权

US07157256B2 Method for producing para-hydroxystyrene and other multifunctional aromatic compounds using two-phase extractive fermentation 失效
标题翻译：使用两相萃取发酵生产对羟基苯乙烯和其他多官能芳族化合物的方法
公开(公告)号：US07157256B2
公开(公告)日：2007-01-02
申请号：US10824237
申请日：2004-04-14
申请人： Arie Ben-Bassat , David J. Lowe
发明人： Arie Ben-Bassat , David J. Lowe
IPC分类号： C12P7/22 , C12P7/40 , C12P7/42
CPC分类号： C12P7/22 , C12P7/28 , Y02E50/17
摘要： Methods are provided for the production and recovery of multifunctional aromatic compounds from a fermentation medium. Preferred multifunctional aromatic compounds include para-hydroxycinnamic acid (pHCA), cinnamic acid (CA), and para-hydroxystyrene (pHS). The multifunctional aromatic compounds may be produced in a biphasic growth medium comprising a fermentation medium having a specified volume of an extractant. The multifunctional aromatic compounds are extracted into the extractant and recovered by standard means.
摘要翻译：提供了用于从发酵培养基生产和回收多官能芳族化合物的方法。优选的多官能芳族化合物包括对羟基肉桂酸（pHCA），肉桂酸（CA）和对羟基苯乙烯（pHS）。多官能芳族化合物可以在包含具有指定体积的提取剂的发酵培养基的双相生长培养基中生产。将多官能芳族化合物提取到萃取剂中，并通过标准方法回收。

15. 发明授权

US5237755A Rapid drying of polyamide resins using high frequency electric fields 失效
标题翻译：使用高频电场快速干燥聚酰胺树脂
公开(公告)号：US5237755A
公开(公告)日：1993-08-24
申请号：US805148
申请日：1991-12-11
申请人： David J. Lowe
发明人： David J. Lowe
IPC分类号： B29B13/06 , B29B13/08 , F26B3/347
CPC分类号： B29B13/065 , F26B3/347
摘要： A process for quickly drying thermoplastic polyamide resin by the use of a high frequency electric field. The process comprises placing the polyamide between at least two electrodes, applying a high frequency voltage to the electrodes to produce a heating rate of the polyamide between 0.5.degree. C. and 50.degree. C./min, and then removing the water evolved from the polyamide.
摘要翻译：一种通过使用高频电场快速干燥热塑性聚酰胺树脂的方法。该方法包括将聚酰胺放置在至少两个电极之间，向电极施加高频电压以产生0.5℃至50℃/分钟之间聚酰胺的加热速率，然后除去聚酰胺放出的水。

16. 发明授权

US5012257A Ink jet color graphics printing 失效
标题翻译：喷墨彩色图形打印
公开(公告)号：US5012257A
公开(公告)日：1991-04-30
申请号：US495011
申请日：1990-03-16
申请人： David J. Lowe , Thomas B. Pritchard
发明人： David J. Lowe , Thomas B. Pritchard
IPC分类号： B41J2/21 , H04N1/23 , H04N1/52
CPC分类号： H04N1/52 , B41J2/2132
摘要： In a color ink jet printing system, an image superpixel (84, 86, 88) consists of a 2 by 2 array of cells (1-4), each cell corresponding to a pixel area on the substrate (80). Each pixel (55) of graphics data is processed to form a 2 by 2 array of bit image data (40), for printing a corresponding superpixel image (68). A superpixel configuration (86), indicating cell location and color of drops of ink for forming a superpixel image, is defined for each desired image color. Superpixel configurations control printing so that drops of ink (Y,M,C) are deposited only an a diagonally adjacent pair of cells (1,4), with no more than two drops of ink per cell, and no more than three drops of ink per superpixel. This superpixel strategy provides for printed images (62,64) perceivable as having the desired image color and having good color saturation, while minimizing bleed across color field boundaries (66).
摘要翻译：在彩色喷墨打印系统中，图像超像素（84,86,88）由2×2的单元阵列（1-4）组成，每个单元对应于基板（80）上的像素区域。图形数据的每个像素（55）被处理以形成2×2的位图数据阵列（40），用于打印对应的超像素图像（68）。为每个期望的图像颜色定义指示单元格位置和用于形成超像素图像的墨的墨滴的颜色的超像素配置（86）。超像素配置控制打印，使得墨滴（Y，M，C）仅沉积在对角相邻的一对单元（1,4）上，每个单元不超过两滴墨水，并且不超过三滴每个超级像素的墨水。该超像素策略提供可感知为具有所需图像颜色并且具有良好色彩饱和度的打印图像（62,64），同时最小化穿过色域边界（66）的渗色。

17. 发明授权

US4215351A Chart recorders 失效
标题翻译：图表记录器
公开(公告)号：US4215351A
公开(公告)日：1980-07-29
申请号：US944559
申请日：1978-09-21
申请人： David J. Lowe
发明人： David J. Lowe
IPC分类号： G01D9/14 , G01R19/12 , G01D15/24 , G01D9/00 , G01D15/16
CPC分类号： G01D9/14 , G01R19/12
摘要： In a potentiometric chart recorder, the speed of the chart motor 22 is, in one mode of operation (AUTO) selected by a switch 32, varied between two values in dependence upon the rate of change or slope of the input signal at 10 as detected in a detector 30. The slow speed is obtained by intermittent operation at the fast speed, and during the non-operative periods power-consuming circuitry e.g. 16, 18, 26 is switched off by a switch 40.
摘要翻译：在电位计图表记录器中，在由开关32选择的一种操作模式（AUTO）中，图表电机22的速度在两个值之间根据检测到的输入信号在10处的变化率或斜率而变化在检测器30中。慢速通过以快速的间歇操作获得，并且在非操作时段期间功耗电路例如 16,18,26由开关40断开。

18. 发明授权

US08557540B2 Methods and systems for removing undissolved solids prior to extractive fermentation in the production of butanol 有权
标题翻译：在生产丁醇中萃取发酵之前去除未溶解固体的方法和系统
公开(公告)号：US08557540B2
公开(公告)日：2013-10-15
申请号：US13163243
申请日：2011-06-17
申请人： Keith H. Burlew , Michael Charles Grady , John W. Hallam , David J. Lowe , Brian Michael Roesch , Joseph J. Zaher
发明人： Keith H. Burlew , Michael Charles Grady , John W. Hallam , David J. Lowe , Brian Michael Roesch , Joseph J. Zaher
IPC分类号： C12P7/16 , C12P7/04 , C12P7/06 , C12P1/00 , C12M1/00 , C12M3/00 , A23J1/14
CPC分类号： C12P7/16 , A23K10/38 , B01D3/002 , B01D11/0492 , B01D21/26 , B01D21/262 , C07C29/86 , C11B1/025 , C11B13/00 , C12F3/10 , C12M1/00 , C12M21/12 , C12M45/04 , C12M45/09 , C12N1/14 , C12N15/00 , C12P7/18 , C12P7/6418 , Y02E50/10 , Y02E50/16 , Y02E50/17 , Y02W30/74
摘要： A method and system for efficiently producing a fermentative product alcohol such as butanol utilizing in situ product extraction are provided. The efficiency is obtained through separating undissolved solids after liquefying a given feedstock to create a feedstock and prior to fermentation, for example, through centrifugation. Removal of the undissolved solids avoids problems associated with having the undissolved solids present during in situ production extraction, and thereby increases the efficiency of the alcohol production.
摘要翻译：提供了利用原位产物提取有效地生产发酵产物醇如丁醇的方法和系统。通过在液化给定原料以产生原料并且在发酵之前，例如通过离心分离未溶解的固体，获得效率。去除未溶解的固体避免了在原位生产提取期间存在未溶解固体的问题，从而提高了醇生产的效率。

19. 发明申请

US20120164302A1 METHODS AND SYSTEMS FOR REMOVING UNDISSOLVED SOLIDS PRIOR TO EXTRACTIVE FERMENTATION IN THE PRODUCTION OF BUTANOL 有权
标题翻译：在丁醇生产中提取发酵前除去未溶解固体的方法和系统
公开(公告)号：US20120164302A1
公开(公告)日：2012-06-28
申请号：US13163243
申请日：2011-06-17
申请人： BRIAN MICHAEL ROESCH , Keith H. Burlew , John W. Hallam , David J. Lowe , Joseph J. Zaher
发明人： BRIAN MICHAEL ROESCH , Keith H. Burlew , John W. Hallam , David J. Lowe , Joseph J. Zaher
IPC分类号： C12P7/16 , A23D9/00 , C12M1/00 , A23K1/00 , C12P7/04 , C12P7/06
CPC分类号： C12P7/16 , A23K10/38 , B01D3/002 , B01D11/0492 , B01D21/26 , B01D21/262 , C07C29/86 , C11B1/025 , C11B13/00 , C12F3/10 , C12M1/00 , C12M21/12 , C12M45/04 , C12M45/09 , C12N1/14 , C12N15/00 , C12P7/18 , C12P7/6418 , Y02E50/10 , Y02E50/16 , Y02E50/17 , Y02W30/74
摘要： A method and system for efficiently producing a fermentative product alcohol such as butanol utilizing in situ product extraction are provided. The efficiency is obtained through separating undissolved solids after liquefying a given feedstock to create a feedstock and prior to fermentation, for example, through centrifugation. Removal of the undissolved solids avoids problems associated with having the undissolved solids present during in situ production extraction, and thereby increases the efficiency of the alcohol production.
摘要翻译：提供了利用原位产物提取有效地生产发酵产物醇如丁醇的方法和系统。通过在液化给定原料以产生原料并且在发酵之前，例如通过离心分离未溶解的固体，获得效率。去除未溶解的固体避免了在原位生产提取期间存在未溶解固体的问题，从而提高了醇生产的效率。

20. 发明授权

US07906617B2 Polyethylene binding peptides and methods of use 有权
标题翻译：聚乙烯结合肽及其使用方法
公开(公告)号：US07906617B2
公开(公告)日：2011-03-15
申请号：US11607672
申请日：2006-12-01
申请人： Scott D. Cunningham , David J. Lowe , John P. O'Brien , Hong Wang , Antoinette E. Wilkins
发明人： Scott D. Cunningham , David J. Lowe , John P. O'Brien , Hong Wang , Antoinette E. Wilkins
IPC分类号： C40B3/06
CPC分类号： G01N33/54353 , C07K7/06 , C07K7/08 , C07K14/001
摘要： Combinatorially generated peptides are provided that have binding affinity for polyethylene (PE). The peptides may be used to deliver benefit agents to various PE surfaces.
摘要翻译：提供了对聚乙烯（PE）具有结合亲和力的组合产生的肽。肽可以用于将有益剂递送到各种PE表面。

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