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11. 发明申请

US20140348763A1 COMPOSITIONS CONTAINING ISOSORBIDE MONOESTER AND ALCOHOLS THAT CONTAIN AT LEAST ONE AROMATIC GROUP 审中-公开
标题翻译：含有至少一个芳香族基团的异构体单体和醇的组合物
公开(公告)号：US20140348763A1
公开(公告)日：2014-11-27
申请号：US14237028
申请日：2012-07-31
申请人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl , Joerg Grohmann
发明人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl , Joerg Grohmann
IPC分类号： A61K31/343 , A61Q19/00 , A61Q1/14 , A61Q5/02 , A61Q19/10 , A61Q15/00 , A61Q19/02 , A61Q19/08 , A61Q19/04 , A61Q17/04 , A61Q1/00 , A01N43/90 , A61K31/045 , A61K8/34 , A61K8/49 , A01N31/14 , A61Q5/06
CPC分类号： A61K31/343 , A01N31/14 , A01N37/10 , A01N39/00 , A01N43/90 , A61K8/34 , A61K8/4973 , A61K31/045 , A61Q1/00 , A61Q1/02 , A61Q1/14 , A61Q5/02 , A61Q5/06 , A61Q15/00 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/04 , A61Q19/08 , A61Q19/10 , A01N31/04 , A01N2300/00
摘要： Compositions comprising isosorbide monoesters and alcohols comprising at least one aromatic groupWhat are described are compositions comprisinga) one or more compounds of the formula (I) in which R is a straight-chain or branched saturated alkyl group having 5 to 11 carbon atoms or a straight-chain or branched mono- or polyunsaturated alkenyl group having 5 to 11 carbon atoms, and b) one or more alcohols comprising at least one aromatic group. The compositions are distinguished in particular by an advantageous antimicrobial activity.
摘要翻译：包含异山梨醇单酯和包含至少一个芳族基团的醇的组合物描述的组合物包含a）一种或多种式（I）化合物，其中R是具有5至11个碳原子的直链或支链饱和烷基或具有5至11个碳原子的直链或支链单或多不饱和烯基，以及b）一种或多种包含至少一个芳族基团的醇。特别地，组合物通过有利的抗微生物活性来区分。

12. 发明申请

US20140329870A1 COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND ISOTHIAZOLINONES 审中-公开
标题翻译：包含异构体单体和异亮氨酸的组合物
公开(公告)号：US20140329870A1
公开(公告)日：2014-11-06
申请号：US14237027
申请日：2012-07-31
申请人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl , Joerg Grohmann
发明人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl , Joerg Grohmann
IPC分类号： A01N43/90 , A01N43/80
CPC分类号： A01N43/90 , A01N43/80 , A01N2300/00
摘要： What are described are compositions comprising a) one or more compounds of the formula (I) in which R is a straight-chain or branched saturated alkyl group having 5 to 11 carbon atoms or a straight-chain or branched mono- or polyunsaturated alkenyl group having 5 to 11 carbon atoms, and b) one or more substances selected from the group consisting of isothiazolinones. The compositions are distinguished in particular by an advantageous antimicrobial activity.
摘要翻译：描述的组合物包含a）一种或多种式（I）化合物，其中R是具有5至11个碳原子的直链或支链饱和烷基或直链或支链单或多不饱和烯基具有5至11个碳原子，和b）一种或多种选自异噻唑啉酮的物质。特别地，组合物通过有利的抗微生物活性来区分。

13. 发明申请

US20140308224A1 COSMETIC, DERMATOLOGICAL OR PHARMACEUTICAL COMPOSITIONS COMPRISING ISOSORBIDE DIESTERS AND UV FILTERS 审中-公开
标题翻译：化妆品，包含异烟碱和紫外线过滤器的化学或药物组合物
公开(公告)号：US20140308224A1
公开(公告)日：2014-10-16
申请号：US14237076
申请日：2012-07-31
申请人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl
发明人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl
IPC分类号： A61K8/49 , A61K8/37 , A61Q17/04 , A61K8/34
CPC分类号： A61K8/4973 , A61K8/345 , A61K8/37 , A61Q17/04
摘要： Cosmetic, dermatological or pharmaceutical compositions comprising isosorbide diesters and UV filtersWhat are described are cosmetic, dermatological or pharmaceutical compositions comprising a) one or more compounds of the formula (I) in which R is a straight-chain or branched saturated alkyl group having 5 to 11 carbon atoms or a straight-chain or branched mono- or polyunsaturated alkenyl group having 5 to 11 carbon atoms, and b) one or more organic or inorganic UV filters.
摘要翻译：包含异山梨醇二酯和紫外线过滤器的化妆品，皮肤病学或药物组合物描述的是化妆品，皮肤病学或药物组合物，其包含a）一种或多种式（I）化合物，其中R是具有5个的直链或支链饱和烷基至11个碳原子或具有5至11个碳原子的直链或支链单或多不饱和链烯基，以及b）一种或多种有机或无机UV滤膜。

14. 发明申请

US20140213665A1 Process For Preparing Acylglycinates And Compositions Comprising Such Compounds 有权
标题翻译：制备包含这些化合物的酰基甘氨酸盐和组合物的方法
公开(公告)号：US20140213665A1
公开(公告)日：2014-07-31
申请号：US14232844
申请日：2012-07-11
申请人： Peter Klug , Franz-Xaver Scherl
发明人： Peter Klug , Franz-Xaver Scherl
IPC分类号： A61K8/42 , C07C233/47 , A61Q19/00 , C07C233/49 , A61Q19/10
CPC分类号： C07C231/02 , A61K8/046 , A61K8/42 , A61K8/44 , A61K8/442 , A61K2800/10 , A61Q19/00 , A61Q19/10 , C07C233/47 , C07C233/49 , C07C233/02
摘要： A process is described for preparing acylglycinates of the formula (I) wherein R1 is a linear or branched, saturated alkanoyl group having 6 to 30 carbon atoms, or is a linear or branched, singly or multiply unsaturated alkenoyl group having 6 to 30 carbon atoms, and Q+ is a cation selected from the alkali metals Na+ and K+, the process being characterized in that glycine is reacted with fatty acid chloride R1Cl, wherein R1 possesses the definition stated in formula (I), in water and in the presence of a basic alkali metal compound which yields cations Q+ selected from Na+ and K+, but in the absence of organic solvents, at 25-50° C., and the fraction of fatty acid chloride R1Cl containing unsaturated acyl groups R1 having 18 carbon atoms, based on the total amount of fatty acid chloride used, is greater than or equal to 2.0% by weight, and at the same time the fraction of fatty acid chloride containing saturated acyl groups having 8 and 10 carbon atoms, based on the total amount of fatty acid chloride used, is greater than, or equal to in each case 3.0% by weight. Also described are compositions comprising acylglycinates of the formula (I).
摘要翻译：描述了制备式（I）的酰基甘氨酸的方法，其中R 1是具有6至30个碳原子的直链或支链饱和烷酰基，或者是具有6至30个碳原子的直链或支链，单或多不饱和链烯酰基，Q +是选自碱金属Na +和K +的阳离子，该方法的特征在于甘氨酸与脂肪酰氯R1Cl反应，其中R1具有式（I）中定义的定义，在水中和在碱性碱金属化合物，其在25-50℃下产生选自Na +和K +，但不存在有机溶剂的阳离子Q +，并且基于具有18个碳原子的不饱和酰基R1的脂肪酰氯R1Cl的级分基于使用的脂肪酰氯的总量大于或等于2.0重量％，同时含有碳原子数为8和10的饱和酰基的脂肪酰氯的分数，基于fa的总量使用tty酰氯，大于或等于每种情况下为3.0重量％。还描述了包含式（I）的酰基甘氨酸盐的组合物。

15. 发明申请

US20120100085A1 COMPOSITION CONTAINING SORBITAN MONOCAPRYLATE AND ALCOHOL 有权
标题翻译：含有SORBITAN MONOCAPRYLATE和ALCOHOL的组合物
公开(公告)号：US20120100085A1
公开(公告)日：2012-04-26
申请号：US13321199
申请日：2010-05-11
申请人： Peter Klug , Sonja Gehm , Guiseppina Kluth , Franz-Xaver Scherl , Maurice Frederic Pilz
发明人： Peter Klug , Sonja Gehm , Guiseppina Kluth , Franz-Xaver Scherl , Maurice Frederic Pilz
IPC分类号： A61K8/92 , A01P1/00 , A61Q5/02 , A61Q17/04 , A61Q19/10 , A01N43/08 , A61Q15/00
CPC分类号： A01N31/14 , A01N31/04 , A01N43/08 , A01N43/16 , A61K8/34 , A61K8/345 , A61K8/4973 , A61K2800/524 , A61Q1/04 , A61Q1/14 , A61Q5/02 , A61Q5/06 , A61Q5/12 , A61Q15/00 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A61Q19/10 , A01N31/02 , A01N25/30 , A01N2300/00
摘要： The invention relates to liquid compositions which contain a) from 5 to 95% by weight of sorbitan monocaprylate and b) from 5 to 95% by weight of one or more alcohols of formula (1) R—OH (1), wherein R is a group consisting of carbon, hydrogen and optionally oxygen atoms with 5 to 12, preferably 6 to 11, carbon atoms, and the carbon atoms can be interlinked in, a linear, branched and/or cyclic fashion via saturated, unsaturated and/or aromatic carbon-carbon bonds and the groups can also contain ether units and hydrogen atoms and/or hydroxyl groups can be bound to the individual carbon atoms. The liquid compositions are suitable for the production of cosmetic, dermatological or pharmaceutical products.
摘要翻译：本发明涉及液体组合物，其含有a）5至95重量％的脱水山梨糖醇单辛酸酯和b）5至95重量％的一种或多种式（1）R-OH（1）的醇，其中R为由碳，氢和任选的具有5至12个，优选6至11个碳原子的氧原子组成的基团，并且碳原子可以通过饱和，不饱和和/或芳族以直链，支链和/或环状的方式互连碳 - 碳键，并且基团也可以含有醚单元，氢原子和/或羟基可以结合到各个碳原子上。液体组合物适用于生产化妆品，皮肤病学或药物产品。

16. 发明申请

US20100305358A1 Method For The Production Of Acyl Glycinates By Means Of Direct Oxidation 有权
标题翻译：通过直接氧化生产酰基甘氨酸的方法
公开(公告)号：US20100305358A1
公开(公告)日：2010-12-02
申请号：US12812011
申请日：2009-01-07
申请人： Peter Klug , Achim Stankowiak , Oliver Franke , Franz-Xaver Scherl , Ulf Pruesse , Nadine Decker , Klaus-Dieter Vorlop
发明人： Peter Klug , Achim Stankowiak , Oliver Franke , Franz-Xaver Scherl , Ulf Pruesse , Nadine Decker , Klaus-Dieter Vorlop
IPC分类号： C07C51/235
CPC分类号： C07C231/12 , C07C233/47
摘要： A method is described for producing acyl glycinate salts of formula (II) in which R1 represents a saturated linear or branched alkyl radical comprising 1 to 21 carbon atoms or a monounsaturated or polyunsaturated linear or branched alkenyl radical comprising 2 to 21 carbon atoms, and B represents a cation, and/or the corresponding protonated acyl glycinic acid. Said method is characterized in that one or more fatty acid monoethanol amides of formula (I) in which R1 has the meaning indicated above is/are oxidized with oxygen in the presence of an optionally supported bimetallic catalyst consisting of gold and a metal from group VIII of the periodic table in the alkaline medium in order to obtain one or more acyl glycinate salts of formula (II). In order to produce the protonated acyl glycinic acids, the acyl glycinate salt/s of formula (II) is/are additionally reacted with an acid.
摘要翻译：描述了制备式（II）的酰基甘氨酸盐的方法，其中R 1表示包含1至21个碳原子的饱和直链或支链烷基或包含2至21个碳原子的单不饱和或多不饱和直链或支链烯基，B 表示阳离子，和/或相应的质子化酰基甘氨酸。所述方法的特征在于，其中R1具有上述含义的一种或多种式（I）的一种或多种脂肪酸单乙醇酰胺在由金和金属组成的任选负载的双金属催化剂存在下用氧氧化的碱性介质中的周期表，以获得一种或多种式（II）的酰基甘氨酸盐。为了产生质子化的酰基乙二酸，式（II）的酰基甘氨酸盐/另外与酸反应。

17. 发明授权

US09504636B2 Surfactant solutions containing N-methyl-N-oleylglucamines and N-methyl-N-C12-C14-acylglucamines 有权
标题翻译：含有N-甲基-N-油酰基葡萄糖胺和N-甲基-N-C12-C14-酰基葡糖胺的表面活性剂溶液
公开(公告)号：US09504636B2
公开(公告)日：2016-11-29
申请号：US14401796
申请日：2013-05-29
申请人： Peter Klug , Franz-Xaver Scherl , Carina Mildner , Eva-Maria Keitzl
发明人： Peter Klug , Franz-Xaver Scherl , Carina Mildner , Eva-Maria Keitzl
IPC分类号： C11D3/30 , C11D3/32 , C11D3/43 , A61K8/41 , A61K8/34 , A61K8/42 , A61Q5/02 , A61Q19/10
CPC分类号： A61K8/41 , A61K8/34 , A61K8/345 , A61K8/42 , A61K2800/596 , A61Q5/02 , A61Q19/10
摘要： The invention relates to a surfactant solution containing: (a) 28 to 65 wt.-% of a mixture of (a1) 5 to 20 wt.-% of N-methyl-N-oleylglucamine, (a2) 50 to 93 wt.-% of N-methyl-N—C12-C14-acylglucamines, (a3) 0 to 30 wt.-% of other N-methyl-N-acylglucamines, components (a1), (a2) and (a3) adding up to 100 wt.-%, (b) 0 to 20 wt.-% of one or more alcohols, (c) 20 to 72 wt.-% of water, and (d) 0 to 5 wt.-% of additives, components (a), (b), (c) and (d) adding up to 100 wt.-%.
摘要翻译：本发明涉及一种表面活性剂溶液，它含有：（a）28至65重量％的（a1）5-20重量％的N-甲基-N-油基葡糖胺的混合物，（a2）50-93重量％ - N-甲基-N-C12-C14-酰基葡糖胺的百分比，（a3）0-30重量％的其它N-甲基-N-酰基葡糖胺，组分（a1），（a2）和（a3） 100重量％，（b）0至20重量％的一种或多种醇，（c）20至72重量％的水，和（d）0至5重量％的添加剂，组分（a），（b），（c）和（d）加到100重量％。

18. 发明申请

US20150030553A1 USE OF ISOSORBIDE MONOESTERS AS THICKENERS 有权
标题翻译：异硫氰酸酯单体作为增稠剂使用
公开(公告)号：US20150030553A1
公开(公告)日：2015-01-29
申请号：US14237042
申请日：2012-07-31
申请人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl
发明人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl
IPC分类号： A61K47/22 , A01N25/00 , C09D7/12 , A61Q19/10 , C11D3/20 , A61K8/49 , A61Q5/02
CPC分类号： A61K47/22 , A01N25/00 , A01N43/90 , A61K8/042 , A61K8/4973 , A61K2800/10 , A61K2800/48 , A61Q5/02 , A61Q19/10 , C09D7/43 , C09D7/63 , C11D3/2096 , C11D3/221 , C11D17/003
摘要： The use of one or more compounds of the formula (I) in which R is a straight-chain or branched saturated alkyl group having 5 to 11 carbon atoms or a straight-chain or branched mono- or polyunsaturated alkenyl group having 5 to 11 carbon atoms as thickeners is described. The use is preferably in cosmetic, dermatological or pharmaceutical compositions, in crop protection formulations, in washing or cleaning compositions or in paints or coatings.
摘要翻译：使用一种或多种式（I）化合物，其中R是具有5至11个碳原子的直链或支链饱和烷基或具有5至11个碳原子的直链或支链单或多不饱和链烯基描述了作为增稠剂的原子。优选使用化妆品，皮肤病学或药物组合物，作物保护制剂，洗涤或清洁组合物或油漆或涂料中。

19. 发明申请

US20140315996A1 USE OF ISOSORBIDE MONOESTERS AS ANTIMICROBIAL ACTIVE SUBSTANCES 有权
标题翻译：异硫氰酸酯单体作为抗微生物活性物质的使用
公开(公告)号：US20140315996A1
公开(公告)日：2014-10-23
申请号：US14237039
申请日：2012-07-31
申请人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl , Joerg Grohmann
发明人： Maurice Frederic Pilz , Peter Klug , Franz-Xaver Scherl , Joerg Grohmann
IPC分类号： A01N43/90 , A61K31/34 , A61Q19/00 , A61K8/49
CPC分类号： A01N43/90 , A61K8/4973 , A61K31/047 , A61K31/34 , A61K31/341 , A61K45/06 , A61Q17/005 , A61Q19/00 , A61Q19/007 , A61K2300/00
摘要： The use of one or more compounds of the formula (I) in which R is a straight-chain or branched saturated alkyl group having 5 to 11 carbon atoms or a straight-chain or branched mono- or polyunsaturated alkenyl group having 5 to 11 carbon atoms as antimicrobially active compound is described. The use is preferably in cosmetic, dermatological or pharmaceutical compositions, in crop protection formulations, in washing or cleaning compositions or in paints or coatings.
摘要翻译：使用一种或多种式（I）化合物，其中R是具有5至11个碳原子的直链或支链饱和烷基或具有5至11个碳原子的直链或支链单或多不饱和链烯基描述了作为抗微生物活性化合物的原子。优选使用化妆品，皮肤病学或药物组合物，作物保护制剂，洗涤或清洁组合物或油漆或涂料中。

20. 发明授权

US08389756B2 Method for producing alkoxylated phosphoric acid triesters 失效
标题翻译：烷氧基化磷酸三酯的制备方法
公开(公告)号：US08389756B2
公开(公告)日：2013-03-05
申请号：US12671809
申请日：2008-07-29
申请人： Peter Klug , Franz-Xaver Scherl , Waltraud Simsch , Adelgunde Oberhauser
发明人： Peter Klug , Franz-Xaver Scherl , Waltraud Simsch , Adelgunde Oberhauser
IPC分类号： C07F9/09
CPC分类号： C07F9/113 , A61K8/556 , A61K2800/48 , C08G65/327
摘要： The invention relates to a method for producing phosphoric acid triesters of formula (I). According to said method, phosphoric acid or a phosphoric acid derivative selected from orthophosphoric acid, tetraphosphoric decaoxide and polyphosphoric acid is reacted with alkoxylated alcohols of formulae (II) R1—(OA1)x-OH, (III) R2—(OA2)y-OH, and (IV) R3—(OA3)Z-OH, in the molar ratio phosphoric acid or phosphoric acid derivative to alkoxylated alcohol of 1:2.5 to 1:3.3, at between 200 and 240° C.
摘要翻译：本发明涉及一种制备式（I）的磷酸三酯的方法。根据所述方法，将磷酸或选自正磷酸，四磷酸十四烷和多磷酸的磷酸衍生物与式（II）R1-（OA1）x-OH，（Ⅲ）R2-（OA2）y的烷氧基化醇反应 -OH和（IV）R3-（OA3）Z-OH，以磷酸或磷酸衍生物与烷氧基化醇的摩尔比为1:2.5至1:3.3，在200和240℃之间。

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