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11. 发明授权

US08501681B2 Macrocyclic hepatitis C virus serine protease inhibitors 有权
标题翻译：大环丙型肝炎病毒丝氨酸蛋白酶抑制剂
公开(公告)号：US08501681B2
公开(公告)日：2013-08-06
申请号：US11768712
申请日：2007-06-26
申请人： Deqiang Niu , Dong Liu , Joel D. Moore , Guoyou Xu , Ying Sun , Yonghua Gai , Datong Tang , Yat Sun Or , Zhe Wang
发明人： Deqiang Niu , Dong Liu , Joel D. Moore , Guoyou Xu , Ying Sun , Yonghua Gai , Datong Tang , Yat Sun Or , Zhe Wang
IPC分类号： A61K30/00 , A01N37/18
CPC分类号： C07D245/04 , A61K38/212 , A61K38/215 , C07D403/12 , A61K2300/00
摘要： The present invention relates to compounds, including compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
摘要翻译：本发明涉及包括式I化合物或其药学上可接受的盐，酯或前药的化合物，其抑制丝氨酸蛋白酶活性，特别是丙型肝炎病毒（HCV）NS3-NS4A蛋白酶的活性。因此，本发明的化合物干扰丙型肝炎病毒的生命周期，也可用作抗病毒剂。本发明还涉及药物组合物，其包含用于给患有HCV感染的受试者施用的上述化合物。本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的HCV感染的方法。

12. 发明申请

US20130185359A1 METHOD AND APPARATUS FOR CONTEXT-BASED GROUPING 有权
标题翻译：基于上下文分组的方法与装置
公开(公告)号：US20130185359A1
公开(公告)日：2013-07-18
申请号：US13812110
申请日：2010-06-29
申请人： Dong Liu , Wenwei Xue , Zhan-jiang Song
发明人： Dong Liu , Wenwei Xue , Zhan-jiang Song
IPC分类号： H04L29/08
CPC分类号： H04L67/24 , G06F17/30035
摘要： An approach is provided for determining context-based groups based on context information. An input from a device specifying one or more criteria to determine a context-based group from among a plurality of other devices is received. The context information associated with the plurality of other devices is determined. The context-based group is determined based, at least in part, on the context information and the criteria.
摘要翻译：提供了一种基于上下文信息来确定基于上下文的组的方法。接收来自指定用于从多个其他设备中确定基于上下文的组的一个或多个准则的设备的输入。确定与多个其他设备相关联的上下文信息。基于上下文的组是至少部分地基于上下文信息和标准来确定的。

13. 发明授权

US08396312B2 Vision-based compression 有权
标题翻译：基于视觉的压缩
公开(公告)号：US08396312B2
公开(公告)日：2013-03-12
申请号：US13177434
申请日：2011-07-06
申请人： Xiaoyan Sun , Feng Wu , Shipeng Li , Dong Liu
发明人： Xiaoyan Sun , Feng Wu , Shipeng Li , Dong Liu
IPC分类号： G06K9/36
CPC分类号： H04N19/12 , G06T7/12 , H04N19/17 , H04N19/61
摘要： Systems and methods provide vision-based image compression. In one implementation, inpainting is the vision-based technique selected to augment a conventional signal-processing-based technique. For some regions of a source image, an exemplary system efficiently extracts and organizes structural edge information instead of compressing the regions. In one implementation, the system applies binary curve fitting to capture the edge information. A structure-aware inpainter in the decoder can then restore the regions via the edge information, which occupies very little data space or minimal bandwidth in a bitstream that is transmitted from encoder to decoder. Key visual components of the image can still be conventionally compressed. Extracting edge information for some regions instead of compressing them considerably increases overall image compression.
摘要翻译：系统和方法提供基于视觉的图像压缩。在一个实现中，修复是基于视觉的技术，其被选择用于增加常规的基于信号处理的技术。对于源图像的一些区域，示例性系统有效地提取并组织结构边缘信息，而不是压缩该区域。在一个实现中，系统应用二进制曲线拟合来捕获边缘信息。然后，解码器中的结构感知输入器可以经由边缘信息来恢复区域，该边缘信息在从编码器传送到解码器的比特流中占据非常小的数据空间或最小带宽。图像的主要视觉部件仍然可以被传统地压缩。为某些区域提取边缘信息而不是压缩边缘信息显着增加了整体图像压缩。

14. 发明申请

US20120230427A1 MULTI-FORMAT VIDEO DECODER WITH FILTER VECTOR PROCESSING AND METHODS FOR USE THEREWITH 有权
标题翻译：具有滤波器矢量处理的多格式视频解码器及其使用方法
公开(公告)号：US20120230427A1
公开(公告)日：2012-09-13
申请号：US13076568
申请日：2011-03-31
申请人： Edward Hong , Dong Liu , Hongri Wang , Kai Yang
发明人： Edward Hong , Dong Liu , Hongri Wang , Kai Yang
IPC分类号： H04N7/26
CPC分类号： H04N19/103 , H04N19/136 , H04N19/436 , H04N19/44 , H04N19/61 , H04N19/91
摘要： A video decoder includes an entropy decoding device that generates entropy decoded (EDC) data from an encoded video signal. A multi-format video decoding device includes a plurality of vector processor units that generate a decoded video signal from the EDC data. The plurality of vector processing units includes at least one filter vector processor that operates in conjunction with a plurality of programmable filter parameters.
摘要翻译：视频解码器包括从编码视频信号产生熵解码（EDC）数据的熵解码装置。多格式视频解码装置包括从EDC数据生成解码视频信号的多个矢量处理器单元。多个矢量处理单元包括至少一个与多个可编程滤波器参数相结合的滤波器矢量处理器。

15. 发明授权

US08211891B2 Difluoromethyl-containing macrocyclic compounds as hepatitis C virus inhibitors 有权
标题翻译：含二氟甲基的大环化合物作为丙型肝炎病毒抑制剂
公开(公告)号：US08211891B2
公开(公告)日：2012-07-03
申请号：US12433191
申请日：2009-04-30
申请人： Yonghua Gai , Dong Liu , Joel D. Moore , Yat Sun Or , Zhe Wang
发明人： Yonghua Gai , Dong Liu , Joel D. Moore , Yat Sun Or , Zhe Wang
IPC分类号： C07D225/00 , C07D295/00 , A61K31/495 , A61P31/22
CPC分类号： C07D513/22 , C07D498/22 , C07D515/22
摘要： The present invention discloses compounds of formula I or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
摘要翻译：本发明公开了式I化合物或其药学上可接受的盐，酯或前药：其抑制丝氨酸蛋白酶活性，特别是丙型肝炎病毒（HCV）NS3-NS4A蛋白酶的活性。因此，本发明的化合物干扰丙型肝炎病毒的生命周期，也可用作抗病毒剂。本发明还涉及药物组合物，其包含用于给患有HCV感染的受试者施用的上述化合物。本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的HCV感染的方法。

16. 发明申请

US20120158686A1 Image Tag Refinement 审中-公开
标题翻译：图像标签细化
公开(公告)号：US20120158686A1
公开(公告)日：2012-06-21
申请号：US12971880
申请日：2010-12-17
申请人： Xian-Sheng Hua , Dong Liu , Meng Wang , Hong-Jiang Zhang
发明人： Xian-Sheng Hua , Dong Liu , Meng Wang , Hong-Jiang Zhang
IPC分类号： G06F17/30
CPC分类号： G06F16/5866
摘要： A computing device configured to determine a subset of the tags associated with at least one image of a plurality of received, tagged images is described herein. The computing device performs the determining based on one or more measures of consistency of visual similarity between ones of the images with semantic similarity between tags of the ones of the images.
摘要翻译：被配置为确定与多个接收到的标记图像中的至少一个图像相关联的标签的子集的计算设备在此被描述。计算装置基于图像中的一个图像之间的视觉相似性的一致性的测量来执行确定，其中图像的标签之间具有语义相似性。

17. 发明申请

US20120055735A1 Acoustic Attenuation Method Based on Acoustic Ray Deflection Theory and a Muffler 有权
标题翻译：基于声光偏转理论和消声器的声衰减方法
公开(公告)号：US20120055735A1
公开(公告)日：2012-03-08
申请号：US13203699
申请日：2010-02-26
申请人： Yadong Lu , Dong Liu , Qiang Wang
发明人： Yadong Lu , Dong Liu , Qiang Wang
IPC分类号： F01N1/10
CPC分类号： G10K11/16 , B64D33/06 , F01N1/24 , F01N2240/02 , F01N2240/04 , F01N2260/02 , F01N2510/04 , G10K11/26
摘要： A noise elimination method based on sound ray refraction theory and the muffler thereby are disclosed. The method use s low temperature refrigeration system (2) to form a temperature gradient inside and outside the chamber of the muffler, and the temperature inside the pipe wall of the chamber is higher than the outside. The temperature gradient may force sound ray to reflect towards the low temperature direction, so the noise of the system may be captured and reduced. The muffler comprises a housing (1) whose inner wall is laid with a sound absorbing structure (4), and on the outer wall of the housing (1) is provide a low temperature refrigerating system (2). The system covers at least of the area of the outer wail of muffler housing (1) and combines with a temperature control system (3) to realize quantitative control of the temperature gradient. The muffler improves the noise-absorbing effect of the existing muffler effectively.
摘要翻译：公开了基于声线折射理论和消声器的噪声消除方法。该方法使用低温制冷系统（2）在消声器室内外形成温度梯度，室内管壁内部温度高于外部。温度梯度可能迫使声线向低温方向反射，因此可以捕获和减少系统的噪声。所述消音器包括：内壁铺设有吸声结构（4）的壳体（1），并且在所述壳体（1）的外壁上设置有低温制冷系统（2）。该系统至少覆盖消音器外壳（1）的外围区域，并与温度控制系统（3）组合，实现温度梯度的定量控制。消声器可有效提高现有消声器的噪音吸收效果。

18. 发明授权

US07755645B2 Object-based image inpainting 有权
标题翻译：基于对象的图像修复
公开(公告)号：US07755645B2
公开(公告)日：2010-07-13
申请号：US11615537
申请日：2007-03-29
申请人： Xiaoyan Sun , Dong Liu , Feng Wu , Shipeng Li
发明人： Xiaoyan Sun , Dong Liu , Feng Wu , Shipeng Li
IPC分类号： G09G5/00
CPC分类号： G06T11/60 , G06T5/005
摘要： Systems and methods provide object-based image inpainting. The object-based inpainting can recover part of a missing object or can synthesize visual objects that are entirely missing. In one implementation, an exemplary system generates a target visual object to be inpainted into an image, by geometrically matching key features with a model visual object that can be selected from the same or another image. Borders of the target object are refined through pixel-based contour deformation and textures for the target object are obtained either by pixel interpolation or by patch-based modeling of pre-existing texture in the image. Graph-cut segmentation rectifies image overlap as the target object is embedded in the image. Poisson editing filters visual seams, and edge filling completes visual gaps around the border of the target object.
摘要翻译：系统和方法提供基于对象的图像修复。基于对象的修复可以恢复缺少对象的一部分，或者可以合成完全缺失的可视对象。在一个实现中，示例性系统通过将关键特征与可以从相同图像或另一图像中选择的模型视觉对象几何匹配来生成要修饰成图像的目标视觉对象。通过基于像素的轮廓变形来改进目标对象的边界，通过像素插值或通过图像中预先存在的纹理的基于块的建模来获得目标对象的纹理。当目标物体嵌入在图像中时，图形分割会整理图像重叠。泊松编辑过滤视觉接缝，边缘填充完成目标物体边界周围的视觉间隙。

19. 发明授权

US07725504B2 Method and apparatus for helping user form structured diagram from unstructured information source 有权
标题翻译：帮助用户从非结构化信息源形成结构图的方法和装置
公开(公告)号：US07725504B2
公开(公告)日：2010-05-25
申请号：US11390924
申请日：2006-03-28
申请人： Zhao Ming Qiu , Guo Tong Xie , Dong Liu , Gang Hu
发明人： Zhao Ming Qiu , Guo Tong Xie , Dong Liu , Gang Hu
IPC分类号： G06F7/00 , G06F9/45 , G06F17/00
CPC分类号： G06F17/30731 , G06F17/3002 , G06F2217/74
摘要： The present invention provides a method and apparatus for helping a user form a structured diagram from an unstructured information source. Starting with one or more key information elements such as some special words, the requests of a customer contained in the information source can be obtained by performing interactive and iterative searching in the unstructured information source such as text, audio, video and etc., the artifacts representing them are drawn in the diagram, and linkages are established between the artifacts and the corresponding contents in the information source. The present invention also proposes that the distribution of established linkages can be used to check whether all the requests in the information source have been extracted in the diagram. Further, various levels of warnings can be shown according to the density of linkage distribution. Therefore the user can draw a structured diagram more conveniently and quickly, and can perform checking and reusing more easily.
摘要翻译：本发明提供了一种帮助用户从非结构化信息源形成结构化图的方法和装置。从一个或多个关键信息元素（例如一些特殊字）开始，可以通过在非结构化信息源（例如文本，音频，视频等）中执行交互式和迭代搜索来获得信息源中包含的客户的请求，在图中绘制代表它们的工件，并且在工件和信息源中的相应内容之间建立联系。本发明还提出，所建立的链接的分布可以用于检查信息源中的所有请求是否已经在图中被提取。此外，可以根据联动分配的密度显示各种警告级别。因此，用户可以更方便快捷地绘制结构化图表，并可以更轻松地执行检查和重用。

20. 发明授权

US07605126B2 Acylaminoheteroaryl hepatitis C virus protease inhibitors 有权
标题翻译：酰氨基杂芳基丙型肝炎病毒蛋白酶抑制剂
公开(公告)号：US07605126B2
公开(公告)日：2009-10-20
申请号：US11503502
申请日：2006-08-11
申请人： Deqiang Niu , Joel D. Moore , Dong Liu , Yonghua Gai , Zhigang Chen , Yat Sun Or , Zhe Wang
发明人： Deqiang Niu , Joel D. Moore , Dong Liu , Yonghua Gai , Zhigang Chen , Yat Sun Or , Zhe Wang
IPC分类号： A61K38/12 , C07K5/12 , A61K38/06 , C07K5/08
CPC分类号： C07D487/04 , C07D403/14 , C07D409/14 , C07D417/14
摘要： The present invention discloses compounds of formulae I and II, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
摘要翻译：本发明公开了式I和II的化合物或其药学上可接受的盐，酯或前药：其抑制丝氨酸蛋白酶活性，特别是丙型肝炎病毒（HCV）NS3-NS4A蛋白酶的活性。因此，本发明的化合物干扰丙型肝炎病毒的生命周期，也可用作抗病毒剂。本发明还涉及药物组合物，其包含用于给患有HCV感染的受试者施用的上述化合物。本发明还涉及通过施用包含本发明化合物的药物组合物来治疗受试者的HCV感染的方法。

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