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11. 发明申请

US20110230840A1 GUIDEWIRE HAVING LINEAR CHANGE IN STIFFNESS 有权
标题翻译：具有线性变化的GUIDEWIRE
公开(公告)号：US20110230840A1
公开(公告)日：2011-09-22
申请号：US13150973
申请日：2011-06-01
申请人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark T. Richardson , Kent C. Stalker , Olin J. Palmer
发明人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark T. Richardson , Kent C. Stalker , Olin J. Palmer
IPC分类号： A61M25/09
CPC分类号： A61B5/6851 , A61M25/09 , A61M2025/09083 , A61M2025/09175
摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.
摘要翻译：本发明涉及一种具有多个具有至少两个相邻的远端锥形芯段的多个远端锥形芯部段的远端部分，其中最远端锥形芯部段优选地具有比近端相邻的锥形芯部分更大的锥度。本发明还涉及一种细长的体内装置，优选的导丝或其一部分，其具有芯构件或类似物，多个相邻的锥形段具有锥形角，该锥形角构造成在纵向截面上产生刚度线性变化的设备。该装置还可以具有连续变化的锥角的芯部分，以产生曲线轮廓，该轮廓优选被配置成在装置的纵向部分上产生芯的刚度的线性变化。

12. 发明授权

US06390993B1 Guidewire having linear change in stiffness 有权
标题翻译：导丝具有刚度线性变化
公开(公告)号：US06390993B1
公开(公告)日：2002-05-21
申请号：US09203140
申请日：1998-12-01
申请人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark Richardson
发明人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark Richardson
IPC分类号： A61B500
CPC分类号： A61B5/6851 , A61M25/09 , A61M2025/09083 , A61M2025/09175
摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.
摘要翻译：本发明涉及一种具有多个具有至少两个相邻的远端锥形芯段的多个远端锥形芯部段的远端部分，其中最远端锥形芯部段优选地具有比近端相邻的锥形芯部分更大的锥度。本发明还涉及一种细长的体内装置，优选的导丝或其一部分，其具有芯构件或类似物，多个相邻的锥形段具有锥形角，该锥形角构造成在纵向截面上产生刚度线性变化的设备。该装置还可以具有连续变化的锥角的芯部分，以产生曲线轮廓，该轮廓优选被配置成在装置的纵向部分上产生芯的刚度的线性变化。

13. 发明授权

US07878985B2 Guidewire having linear change in stiffness 有权
标题翻译：导丝具有刚度线性变化
公开(公告)号：US07878985B2
公开(公告)日：2011-02-01
申请号：US10659930
申请日：2003-09-11
申请人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark T. Richardson , Kent C. Stalker , Olin J. Palmer
发明人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark T. Richardson , Kent C. Stalker , Olin J. Palmer
IPC分类号： A61B5/00
CPC分类号： A61B5/6851 , A61M25/09 , A61M2025/09083 , A61M2025/09175
摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.
摘要翻译：本发明涉及一种具有多个具有至少两个相邻的远端锥形芯段的多个远端锥形芯部段的远端部分，其中最远端锥形芯部段优选地具有比近端相邻的锥形芯部分更大的锥度。本发明还涉及一种细长的体内装置，优选的导丝或其一部分，其具有芯部件，该芯部件具有多个相邻的锥形部分，该锥形部分具有锥形角度，该锥形角度构造成在该装置的纵向部分上产生刚度线性变化。该装置还可以具有连续变化的锥角的芯部分，以产生曲线轮廓，该轮廓优选被配置成在装置的纵向部分上产生芯的刚度的线性变化。

14. 发明授权

US08308660B2 Guidewire having linear change in stiffness 有权
标题翻译：导丝具有刚度线性变化
公开(公告)号：US08308660B2
公开(公告)日：2012-11-13
申请号：US13150973
申请日：2011-06-01
申请人： Wayne E. Cornish , John F. Schreiner , James M. Jacobs , Marc M. Jalisi , Mark T. Richardson , Kent C. B. Stalker , Olin J. Palmer
发明人： Wayne E. Cornish , John F. Schreiner , James M. Jacobs , Marc M. Jalisi , Mark T. Richardson , Kent C. B. Stalker , Olin J. Palmer
IPC分类号： A61B5/00
CPC分类号： A61B5/6851 , A61M25/09 , A61M2025/09083 , A61M2025/09175
摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.
摘要翻译：本发明涉及一种具有多个具有至少两个相邻的远端锥形芯段的多个远端锥形芯部段的远端部分，其中最远端锥形芯部段优选地具有比近端相邻的锥形芯部分更大的锥度。本发明还涉及一种细长的体内装置，优选的导丝或其一部分，其具有芯构件或类似物，多个相邻的锥形段具有锥形角，该锥形角构造成在纵向截面上产生刚度线性变化的设备。该装置还可以具有连续变化的锥角的芯部分，以产生曲线轮廓，该曲线轮廓优选地被配置为在装置的纵向部分上产生芯的刚度的线性变化。

15. 发明授权

US07972283B2 Guidewire having linear change in stiffness 有权
标题翻译：导丝具有刚度线性变化
公开(公告)号：US07972283B2
公开(公告)日：2011-07-05
申请号：US12047008
申请日：2008-03-12
申请人： Wayne E. Cornish , John F. Schreiner , James M. Jacobs , Marc M. Jalisi , Mark T. Richardson , Kent C. B. Stalker , Olin J. Palmer
发明人： Wayne E. Cornish , John F. Schreiner , James M. Jacobs , Marc M. Jalisi , Mark T. Richardson , Kent C. B. Stalker , Olin J. Palmer
IPC分类号： A61B5/00
CPC分类号： A61B5/6851 , A61M25/09 , A61M2025/09083 , A61M2025/09175
摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.
摘要翻译：本发明涉及一种具有多个具有至少两个相邻的远端锥形芯段的多个远端锥形芯部段的远端部分，其中最远端锥形芯部段优选地具有比近端相邻的锥形芯部分更大的锥度。本发明还涉及一种细长的体内装置，优选的导丝或其一部分，其具有芯构件或类似物，多个相邻的锥形段具有锥形角，该锥形角构造成在纵向截面上产生刚度线性变化的设备。该装置还可以具有连续变化的锥角的芯部分，以产生曲线轮廓，该轮廓优选被配置成在装置的纵向部分上产生芯的刚度的线性变化。

16. 发明申请

US20090062773A1 GUIDEWIRE HAVING LINEAR CHANGE IN STIFFNESS 有权
标题翻译：具有线性变化的GUIDEWIRE
公开(公告)号：US20090062773A1
公开(公告)日：2009-03-05
申请号：US12047008
申请日：2008-03-12
申请人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark T. Richardson , Kent C. Stalker , Olin J. Palmer
发明人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark T. Richardson , Kent C. Stalker , Olin J. Palmer
IPC分类号： A61M25/09
CPC分类号： A61B5/6851 , A61M25/09 , A61M2025/09083 , A61M2025/09175
摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.
摘要翻译：本发明涉及一种具有多个具有至少两个相邻的远端锥形芯段的多个远端锥形芯部段的远端部分，其中最远端锥形芯部段优选地具有比近端相邻的锥形芯部分更大的锥度。本发明还涉及一种细长的体内装置，优选的导丝或其一部分，其具有芯构件或类似物，多个相邻的锥形段具有锥形角，该锥形角构造成在纵向截面上产生刚度的线性变化的设备。该装置还可以具有连续变化的锥角的芯部分，以产生曲线轮廓，该曲线轮廓优选地被配置为在装置的纵向部分上产生芯的刚度的线性变化。

17. 发明授权

US06666829B2 Guidewire having linear change in stiffness 有权
公开(公告)号：US06666829B2
公开(公告)日：2003-12-23
申请号：US09881290
申请日：2001-06-12
申请人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark Richardson , Kent C. Stalker , Olin J. Palmer
发明人： Wayne E. Cornish , John Schreiner , James Jacobs , Marc M. Jalisi , Mark Richardson , Kent C. Stalker , Olin J. Palmer
IPC分类号： A61B500
CPC分类号： A61B5/6851 , A61M25/09 , A61M2025/09083 , A61M2025/09175
摘要： The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.

18. 发明授权

US07736301B1 Rotatable ferrules and interfaces for use with an optical guidewire 失效
标题翻译：可旋转套圈和与光导线一起使用的接口
公开(公告)号：US07736301B1
公开(公告)日：2010-06-15
申请号：US10025515
申请日：2001-12-18
申请人： William E. Webler , Andrej M. Chudy , Marc M. Jalisi , Kevin M. Phillips , Michael D. Whitt , Susan Norton
发明人： William E. Webler , Andrej M. Chudy , Marc M. Jalisi , Kevin M. Phillips , Michael D. Whitt , Susan Norton
IPC分类号： A61B1/07 , G02B6/36
CPC分类号： G02B6/3826 , A61B1/00126 , A61B5/0062 , A61B5/0084 , G02B6/4219 , G02B6/4292
摘要： Devices and methods for passing optical radiation into and out of a body lumen which can include a rotatable ferrule for use in an optical guidewire and methods for using a rotation ferrule. The rotatable ferrule may be either rotatably captured by and free to rotate within a guidewire, or may rotate upon release from a releasable, mechanically stable friction-fit engagement with a guidewire. Sterile interfaces for readily connecting and disconnecting an optical guidewire with and from other optical instrumentation while maintaining the sterility of the guidewire are provided as well as methods for using a sterile interface device. Interface devices can provide either direct or indirect optical and mechanical connection between an optical guidewire and peripheral instrumentation.
摘要翻译：用于将光学辐射传入和流出体腔的装置和方法，所述体腔可以包括用于光导线中的可旋转套圈以及使用旋转套圈的方法。可旋转套圈可以被可旋转地捕获并且在导丝内自由旋转，或者可以在与导丝的可释放的机械稳定的摩擦配合接合释放时旋转。提供用于在保持导丝的无菌性的同时轻松连接和断开与其它光学仪器的光导线的无菌接口以及使用无菌接口装置的方法。接口设备可以在光导线和外围设备之间提供直接或间接的光学和机械连接。

19. 发明授权

US08845519B2 Rotatable ferrules and interfaces for use with an optical guidewire 有权
标题翻译：可旋转套圈和与光导线一起使用的接口
公开(公告)号：US08845519B2
公开(公告)日：2014-09-30
申请号：US12541444
申请日：2009-08-14
申请人： William E. Webler , Andrej M. Chudy , Marc M. Jalisi , Kevin M. Phillips , Michael D. Whitt , Susan Norton
发明人： William E. Webler , Andrej M. Chudy , Marc M. Jalisi , Kevin M. Phillips , Michael D. Whitt , Susan Norton
IPC分类号： A61B1/07 , G02B6/36 , A61B5/00
CPC分类号： G02B6/3826 , A61B1/00126 , A61B5/0062 , A61B5/0084 , G02B6/4219 , G02B6/4292
摘要： Devices and methods for passing optical radiation into and out of a body lumen may include a rotatable ferrule for use in an optical guidewire and methods for using a rotatable ferrule. The rotatable ferrule may be either rotatably captured by and free to rotate within a guidewire, or may rotate upon release from a releasable, mechanically stable friction-fit engagement with a guidewire. Sterile interfaces for readily connecting and disconnecting an optical guidewire with and from other optical instrumentation while maintaining the sterility of the guidewire, and methods for using a sterile interface device are disclosed. Interface devices can be used to provide either direct or indirect optical and mechanical connection between an optical guidewire and peripheral instrumentation.
摘要翻译：用于将光学辐射传入和流出体腔的装置和方法可包括用于光导线的可旋转套圈以及使用可旋转套圈的方法。可旋转套圈可以被可旋转地捕获并且在导丝内自由旋转，或者可以在与导丝的可释放的机械稳定的摩擦配合接合释放时旋转。公开了用于在保持导线的无菌性的同时轻松地连接和断开与其他光学仪器的光导线的无菌接口，以及使用无菌接口装置的方法。接口设备可用于在光导线和外围设备之间提供直接或间接的光学和机械连接。

20. 发明授权

US06623520B2 Multilayer stent 有权
公开(公告)号：US06623520B2
公开(公告)日：2003-09-23
申请号：US10132925
申请日：2002-04-26
申请人： Marc M. Jalisi
发明人： Marc M. Jalisi
IPC分类号： A61F206
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2210/0076 , A61F2230/0013
摘要： A composite stent having a substrate tube made of stainless steel, a nickel-cobalt-chromium-molybdenum alloy, or chonichrome with at least one metal cladding tube is disclosed. Specifically, the substrate tube is placed within a metal cladding tube made of platinum, gold, tantalum, tungsten, platinum-iridium, palladium, or nickel-titanium, preferably with an interference fit therebetween. The composite, laminate tube then undergoes a series of rolling or cold drawing processes interspersed with heat treating to release built up stresses. When the final diameter of the laminate tube is reached, the cladding has been laminated to the exterior of the substrate tube by a bond generated from the rolling and/or cold drawing operations. The finished laminate tube is then cut by laser cutting or chemical etching to form a suitable stent pattern.

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