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11. 发明申请

US20120238723A1 PRODUCTION METHOD OF 11-SUGAR SIALYLGLYCOPEPTIDE 有权
标题翻译：十一烷磺酰胆碱的生产方法
公开(公告)号：US20120238723A1
公开(公告)日：2012-09-20
申请号：US13394197
申请日：2010-09-03
申请人： Shuichi Sugawara , Kenji Osumi
发明人： Shuichi Sugawara , Kenji Osumi
IPC分类号： C07K1/30
CPC分类号： C07K7/06 , C07K9/00 , C08B37/0063
摘要： It is an object of the present invention to provide a method for producing an 11-sugar sialylglycopeptide easily and with good yield and a high degree of purity on an industrial scale from defatted bird egg yolks. The present invention provides a production method of an 11-sugar sialylglycopeptide. More specifically, the present invention provides a production method of an 11-sugar sialylglycopeptide comprising: an extraction step of extracting defatted bird egg yolks with water or a salt solution to obtain a liquid extract of a glycopeptide, a precipitation step of adding the liquid extract to a water-soluble organic solvent to precipitate the glycopeptide, and a desalting step of desalting the precipitate.
摘要翻译：本发明的一个目的是提供一种从脱脂鸟蛋黄制成工业规模的11-糖唾液酸糖肽的方法，其制备方法良好，产率高，纯度高。本发明提供了11-糖唾液酸糖肽的制备方法。更具体地说，本发明提供了11-糖唾液酸糖肽的制造方法，包括：提取步骤，用水或盐溶液提取脱脂鸟蛋黄，得到糖肽的液体提取物，添加液体提取物的沉淀步骤向水溶性有机溶剂中沉淀糖肽，以及脱盐脱盐步骤。

12. 发明申请

US20110150410A1 Curable liquid composition, cured layer and coated optical fiber 审中-公开
标题翻译：可固化液体组合物，固化层和涂层光纤
公开(公告)号：US20110150410A1
公开(公告)日：2011-06-23
申请号：US12929834
申请日：2011-02-18
申请人： Shuichi Sugawara , Hiroshi Miyazawa , Masahito Mase , Takeo Shigemoto
发明人： Shuichi Sugawara , Hiroshi Miyazawa , Masahito Mase , Takeo Shigemoto
IPC分类号： G02B6/00 , C09D175/14 , C08F2/46
CPC分类号： C03C25/1065 , C08K5/3435 , C08K5/5415 , C09D4/00 , C09D7/63
摘要： A curable liquid resin optical fiber coating composition comprising 0.1 to 10 wt %, relative to the total weight of the composition, of an alkoxysilane compound (A) which does not contain a radically polymerizable functional group, and 0.01 to 1 wt %, relative to the total weight of the composition, of a hindered amine compound (B). This curable liquid resin composition produces a cured product that ensures a high n-value of the coated optical fiber and an excellent fiber strength after coating removal.
摘要翻译：相对于组合物的总重量为0.1〜10重量％的可固化液晶树脂光纤涂层组合物，相对于不含自由基聚合性官能团的烷氧基硅烷化合物（A）为0.01〜1重量％受体胺化合物（B）的组合物的总重量。该可固化液体树脂组合物产生确保涂层光纤的n值高，并且在除去涂层后具有优异的纤维强度的固化产物。

13. 发明授权

US5851547A Controlled release drug formulation of open end cylindrical rod form 失效
标题翻译：开放式圆柱形杆形控释药物配方
公开(公告)号：US5851547A
公开(公告)日：1998-12-22
申请号：US762847
申请日：1996-12-10
申请人： Keiji Fujioka , Takeshi Hirasawa , Masako Kajihara , Akihiko Sano , Shuichi Sugawara , Yosuke Urabe
发明人： Keiji Fujioka , Takeshi Hirasawa , Masako Kajihara , Akihiko Sano , Shuichi Sugawara , Yosuke Urabe
IPC分类号： A61K9/00 , A61K9/22 , A61K9/24
CPC分类号： A61K9/0092
摘要： A drug formulation for producing sustained therapeutic efficacy, which releases at least one water-soluble drug over a prolonged period of time at a substantially constant rate wherein said drug formulation comprises (a) a nondisintegrating inner layer comprised of a biocompatible material that contains at least one uniformly dispersed water-soluble drug; and (b) an outer layer comprised of a biocompatible material that surrounds the circumference of the said inner layer, is impermeable to water, and is capable of controlling the swelling of the inner layer; wherein the ratio of the axial length of the drug formulation to the cross-sectional diameter of the inner layer is one or more and wherein one or both ends of the inner layer are open so as to come into direct contact with the external environment.
摘要翻译：一种用于产生持续治疗功效的药物制剂，其以基本恒定的速率在长时间内释放至少一种水溶性药物，其中所述药物制剂包含（a）由生物相容性材料组成的非整合内层，所述生物相容性材料至少包含一种均匀分散的水溶性药物; 和（b）由围绕所述内层的圆周的生物相容性材料构成的外层，不透水，并且能够控制内层的膨胀; 其中所述药物制剂的轴向长度与所述内层的横截面直径的比率是一个或多个，并且其中所述内层的一端或两端是敞开的，以便与外部环境直接接触。

14. 发明授权

US5204327A Treatment of cerebral edema with ANP pharmaceutical compositions 失效
标题翻译：用ANP药物组合物治疗小儿EDEMA
公开(公告)号：US5204327A
公开(公告)日：1993-04-20
申请号：US435659
申请日：1989-11-13
申请人： Takao Kiyota , Shuichi Sugawara , Hiroshi Hayashi
发明人： Takao Kiyota , Shuichi Sugawara , Hiroshi Hayashi
IPC分类号： A61K38/00 , C07K14/58
CPC分类号： C07K14/58 , A61K38/00
摘要： A pharmaceutical composition and its use in the treatment of cerebral edema are provided wherein the composition comprises an atrial natriuretic peptide having an amino acid sequence of 28 amino acids and at least one pharmaceutically acceptable carrier, diluent or excipient.

15. 发明授权

US4264431A Oil sand treating system 失效
标题翻译：油砂处理系统
公开(公告)号：US4264431A
公开(公告)日：1981-04-28
申请号：US47081
申请日：1979-06-11
申请人： Chiwane Ishikawa , Shuichi Sugawara
发明人： Chiwane Ishikawa , Shuichi Sugawara
IPC分类号： C10B53/06 , C10G1/00 , C10G9/36
CPC分类号： C10G9/36 , C10G1/006
摘要： Residue of distillation, preferably under reduced pressure of oil sand bitumen is thermally treated in a liquid state at a temperature of 350.degree.-450.degree. C. by blowing thereinto an inert heating medium, preferably a superheated steam at a temperature of not lower than the temperature of the residue in a reaction step for 20 to 90 min to crack the residue for converting the residue to a crude synthetic oil, a combustible pitch and a gas, the resultant pitch being utilized to the steps of recovery of oil sand bitumen from oil sand and of distillation as fuel.
摘要翻译：蒸馏残渣优选在油砂沥青的减压下，在350〜-450℃的温度下以液态进行热处理，吹入惰性加热介质，优选过热蒸汽，温度不低于在反应步骤中将残余物的温度保持20-90分钟，以将残渣转化成粗合成油，可燃沥青和气体的残余物，所得沥青用于从油中回收油砂沥青的步骤砂和蒸馏作为燃料。

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