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11. 发明申请

US20080161515A1 Succinate-Containing Polymerization Catalyst System Using n-Butylmethyldimethoxysilane for Preparation of Polypropylene Film Grade Resins 失效
标题翻译：使用正丁基甲基二甲氧基硅烷制备聚丙烯薄膜级树脂的含琥珀酸酯聚合催化剂体系
公开(公告)号：US20080161515A1
公开(公告)日：2008-07-03
申请号：US11958874
申请日：2007-12-18
申请人： Kenneth P. Blackmon , Joseph L. Thorman , Shabbir Ahmedbhai Malbari , Michael Wallace
发明人： Kenneth P. Blackmon , Joseph L. Thorman , Shabbir Ahmedbhai Malbari , Michael Wallace
IPC分类号： C08F110/06 , C08F2/00 , B01J31/14 , B01J31/00
CPC分类号： C08F10/06 , C08F110/06 , Y02P20/52 , C08F4/6465 , C08F4/651 , C08F2500/12 , C08F2500/15 , C08F2500/04 , C08F2500/18
摘要： It has been discovered that using n-butylmethyldimethoxysilane (BMDS) as an external electron donor for succinate-containing Ziegler-Natta catalysts can provide a catalyst system that may prepare polypropylene films with improved properties. The catalyst systems of the invention provide for controlled chain defects/defect distribution and thus a regulated microtacticity along with broadened molecular weight distribution.
摘要翻译：已经发现，使用正丁基甲基二甲氧基硅烷（BMDS）作为含琥珀酸的齐格勒 - 纳塔催化剂的外部电子给体可提供可制备具有改进性能的聚丙烯膜的催化剂体系。本发明的催化剂体系提供受控的链缺陷/缺陷分布，从而提供调节的微量活性以及扩大的分子量分布。

12. 发明申请

US20070233202A1 METHOD OF STIMULATION FASTIGIUM NUCLEUS TO TREAT NEUROLOGICAL DISORDERS 有权
标题翻译：刺激核仁治疗神经病变的方法
公开(公告)号：US20070233202A1
公开(公告)日：2007-10-04
申请号：US11761330
申请日：2007-06-11
申请人： Michael Wallace , James Makous
发明人： Michael Wallace , James Makous
IPC分类号： A61N1/04
CPC分类号： A61N1/36082 , A61N1/36103
摘要： A method of treating a neurological disorder comprises introducing an electrical stimulation lead within a patient's head, locating the stimulation lead within the 4th ventricle of the patient's head, and placing the stimulation lead adjacent the fastigium nucleus of the patient's brain. The method may further comprise stimulating the fastigium nucleus with the stimulation lead to treat the neurological disorder, for example, by increasing the flow of blood within the patient's brain.
摘要翻译：治疗神经障碍的方法包括在患者头部内引入电刺激引线，将刺激引线定位在患者头部的第4 脑室内，并将刺激引线放置在邻近于病人的大脑该方法可以进一步包括用刺激引线刺激快镰核，以治疗神经障碍，例如通过增加患者脑内血液的流动。

13. 发明申请

US20070213764A1 Occlusive Cinching Devices and Methods of Use 有权
标题翻译：闭塞切割装置和使用方法
公开(公告)号：US20070213764A1
公开(公告)日：2007-09-13
申请号：US11748221
申请日：2007-05-14
申请人： Tri Tran , Kim Nguyen , Hanh Ho , My Doan , Richard Murphy , Michael Wallace , Clifford Teoh
发明人： Tri Tran , Kim Nguyen , Hanh Ho , My Doan , Richard Murphy , Michael Wallace , Clifford Teoh
IPC分类号： A61M29/00
CPC分类号： A61B17/12113 , A61B17/12022 , A61B17/12172 , A61B17/12186 , A61B17/1219 , A61B2017/1205 , A61B2017/12063
摘要： Methods and devices for blocking orifices and occluding cavities within a patient are provided. The device in one variation comprises first and second tubular members attached to a collapsible sealing element. The device can be placed through an orifice and the collapsible sealing element can be collapsed to seal the orifice. An embolic may be introduced distal to the sealing element to occlude a cavity. The device may incorporate a locking mechanism which can be engaged to lock the sealing element into the collapsed position. The device may incorporate a valve to prevent flow through the tubular members, for example to prevent egress of the embolic from a cavity. The device can be detached to provide a permanent seal of the orifice, and can retain the embolic within the cavity. The device may be used in conjunction with a stent or other retention device to assist the sealing element in maintaining the seal.
摘要翻译：提供了用于阻断患者内的孔和闭塞腔的方法和装置。一个变型中的装置包括附接到可折叠密封元件的第一和第二管状构件。该装置可以通过孔口放置，并且可折叠密封元件可以折叠以密封孔口。可以在密封元件的远侧引入栓塞以封闭空腔。该装置可以包括可以接合以将密封元件锁定到折叠位置的锁定机构。该装置可以包括阀以防止流过管状构件，例如以防止栓塞从空腔排出。该装置可以被拆卸以提供孔口的永久性密封，并且可以将栓塞保持在空腔内。该装置可以与支架或其它保持装置结合使用以帮助密封元件保持密封。

14. 发明申请

US20070135809A1 Precision ablating device 有权
标题翻译：精密烧蚀装置
公开(公告)号：US20070135809A1
公开(公告)日：2007-06-14
申请号：US11286257
申请日：2005-11-23
申请人： David Utley , Robert Garabedian , Michael Wallace
发明人： David Utley , Robert Garabedian , Michael Wallace
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B18/18 , A61B2018/00214 , A61B2018/0022 , A61B2018/00577 , A61B2018/1495 , A61B2018/1807
摘要： Apparatus for treating abnormal mucosa in an alimentary tract are provided. The apparatus include an ablation structure configured to be removably coupled to an endoscope and a deflection mechanism adapted to move the ablation structure with respect to the endoscope and toward a tissue surface.
摘要翻译：提供了用于治疗消化道异常粘膜的装置。该装置包括被配置为可移除地联接到内窥镜的消融结构和适于使消融结构相对于内窥镜移动并朝向组织表面的偏转机构。

15. 发明申请

US20060271097A1 Electrolytically detachable implantable devices 审中-公开
标题翻译：电解离子可植入装置
公开(公告)号：US20060271097A1
公开(公告)日：2006-11-30
申请号：US11140690
申请日：2005-05-31
申请人： Kamal Ramzipoor , Scott McGill , Michael Wallace , Sarah Young , Russell Ford
发明人： Kamal Ramzipoor , Scott McGill , Michael Wallace , Sarah Young , Russell Ford
IPC分类号： A61M29/00
CPC分类号： A61B17/12145 , A61B17/12022 , A61B17/12113 , A61B2017/12063
摘要： Described herein are electrolytically detachable implantable devices and assemblies. In particular, implantable devices and assemblies that are flexible in or near the electrolytically erodable junction region are provided. Also provided are methods of using the devices and assemblies.
摘要翻译：这里描述的是电解可拆卸的可植入装置和组件。特别地，提供了在电解可腐蚀的接合区域中或其附近柔性的可植入装置和组件。还提供了使用装置和组件的方法。

16. 发明申请

US20050251238A1 Intravascular self-anchoring integrated tubular electrode body 失效
标题翻译：血管内自我锚定一体化管状电极体
公开(公告)号：US20050251238A1
公开(公告)日：2005-11-10
申请号：US10841069
申请日：2004-05-06
申请人： Michael Wallace , Robert Garabedian , John Peckham
发明人： Michael Wallace , Robert Garabedian , John Peckham
IPC分类号： A61N1/05 , A61N1/378
CPC分类号： A61N1/057 , A61N1/3787 , A61N2001/0585
摘要： An expandable intravascular medical device is provided. The medical device comprises an expandable tubular body that includes an integrated resilient support structure that forms a plurality of electrically conductive regions to which the lead(s) is coupled. The tubular body further includes at least one electrically insulative element disposed between the conductive regions. In one embodiment, the support structure is skeletal in nature, e.g., it can be formed of a mesh, braid, or coil. The conductive regions can be variously formed by the support structure. For example, the support structure may comprise electrically conductive sub-structures that form the conductive regions. In this case, the sub-structures may be mechanically linked together by the insulative element(s), or they can be directly linked together, and the insulative element(s) can take the form of insulative layer(s) disposed on one or more of the conductive sub-structures. As another example, the support structure can have a conductive core and insulative material disposed over portions of the conductive core. In this case, the exposed core portions form the conductive regions, and the unexposed core portions form the insulative element(s).
摘要翻译：提供可扩张血管内医疗装置。医疗装置包括可扩张的管状体，其包括形成多个导电区域的集成的弹性支撑结构，引线与该多个导电区域相连。管状体还包括设置在导电区域之间的至少一个电绝缘元件。在一个实施例中，支撑结构本质上是骨架的，例如，其可以由网，编织物或线圈形成。导电区域可以由支撑结构各种形成。例如，支撑结构可以包括形成导电区域的导电子结构。在这种情况下，子结构可以通过绝缘元件机械地连接在一起，或者它们可以直接连接在一起，并且绝缘元件可以采取设置在一个或多个绝缘元件上的绝缘层的形式，更多的导电子结构。作为另一示例，支撑结构可以具有设置在导电芯的部分上方的导电芯和绝缘材料。在这种情况下，露出的芯部形成导电区域，未曝光的芯部形成绝缘元件。

17. 发明申请

US20050209609A1 Foreign body retrieval devices 审中-公开
标题翻译：异物检索装置
公开(公告)号：US20050209609A1
公开(公告)日：2005-09-22
申请号：US11064062
申请日：2005-02-23
申请人： Michael Wallace
发明人： Michael Wallace
IPC分类号： A61B17/00 , A61B17/22 , A61B17/24 , A61B17/50
CPC分类号： A61B17/50 , A61B17/221 , A61B2017/00349 , A61B2017/22035 , A61B2017/2212 , A61B2017/2215
摘要： Foreign body retrieval devices suited for initially engaging a foreign body at any location along the length of the foreign body. In one embodiment, a foreign body retrieval device that includes a retriever having a hook at one end; and a snare having an element that is configured to substantially surround, and that substantially surrounds, a portion of the hook when the snare and the retriever are used together to capture a foreign body. In another embodiment, a foreign body retrieval device that includes a retriever having a closed-arm hook at one end; and a snare having an element that is configured to engage the closed-arm hook. Other embodiments are included.
摘要翻译：异物检索装置适合于在异物长度的任何位置最初啮合异物。在一个实施例中，一种异物检索装置，其包括在一端具有钩的检索器; 以及圈套，其具有构造成当所述圈套和所述猎犬一起用于捕获异物时基本上围绕所述钩的一部分并且基本上围绕所述钩的一部分。在另一实施例中，一种异物检索装置，其包括在一端具有闭合臂钩的猎犬; 以及具有构造成接合闭合臂钩的元件的圈套。包括其他实施例。

18. 发明申请

US20050203599A1 Modular stimulation lead network 失效
标题翻译：模块化刺激引线网络
公开(公告)号：US20050203599A1
公开(公告)日：2005-09-15
申请号：US10799271
申请日：2004-03-12
申请人： Robert Garabedian , Michael Wallace
发明人： Robert Garabedian , Michael Wallace
IPC分类号： A61N1/04 , A61N1/05 , A61N1/34 , A61N1/36
CPC分类号： A61N1/36071 , A61N1/0551 , A61N1/36017 , A61N1/36021
摘要： A medical kit and method for treating an ailment, such as chronic pain is provided. The kit comprises first and second medical leads, e.g., stimulation leads. Each lead comprises an elongated body and at least one operative element. The first medical lead comprises a coupling mechanism, such as a slot, and the second medical lead comprises a complementary mechanism, such as a rail, that slidably engages the coupling mechanism of the first medical lead. The method may comprise delivering the first medical lead into a patient's body, e.g., into the epidural space of the patient, and delivering the second medical lead into the patient's body by sliding the complementary coupling mechanism of the second medical lead along the coupling mechanism of the first medical lead.
摘要翻译：提供了用于治疗诸如慢性疼痛之类的疾病的医疗用具和方法。该试剂盒包括第一和第二医疗引线，例如刺激引线。每个引线包括细长主体和至少一个操作元件。第一医疗引线包括诸如槽的联接机构，并且第二医疗引线包括可滑动地接合第一医疗引线的联接机构的互补机构，例如轨道。该方法可以包括将第一医疗引线输送到患者体内，例如进入患者的硬膜外腔，并且通过沿第二医疗引线的联接机构滑动第二医疗引线的互补联接机构，将第二医疗引线输送到患者体内第一个医疗领导。

19. 发明申请

US20050065145A1 Dipeptidyl peptidase inhibitors 有权
公开(公告)号：US20050065145A1
公开(公告)日：2005-03-24
申请号：US10934326
申请日：2004-09-02
申请人： Sheldon Cao , Jun Feng , Stephen Gwaltney , Stephen Kaldor , Jeffrey Stafford , Michael Wallace , Xiao-Yi Xiao , Zhiyuan Zhang
发明人： Sheldon Cao , Jun Feng , Stephen Gwaltney , Stephen Kaldor , Jeffrey Stafford , Michael Wallace , Xiao-Yi Xiao , Zhiyuan Zhang
IPC分类号： C07D401/04 , A61K31/549 , A61K31/513
CPC分类号： C07D401/04
摘要： Compounds, pharmaceuticals, kits and methods are provided for use with DPP-IV inhibitors comprising Formula I: wherein the substituents are as described herein.

20. 发明申请

US20130218153A1 CLEANING DEVICE AND METHODS 有权
公开(公告)号：US20130218153A1
公开(公告)日：2013-08-22
申请号：US13591991
申请日：2012-08-22
申请人： Michael Wallace , David S. Utley , Brent Gerberding , Robert Garabedian
发明人： Michael Wallace , David S. Utley , Brent Gerberding , Robert Garabedian
IPC分类号： A61B18/00
CPC分类号： A61B18/00 , A61B17/00234 , A61B18/04 , A61B2017/320008 , A61B2017/320012
摘要： An apparatus for treating tissue within a lumen may include a therapeutic or diagnostic instrument. A cleaning device may also be supported by the instrument. The cleaning device has a portion of a cleaning surface positioned proximal to the distal end of the cleaning device.

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