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11. 发明授权

US08009885B2 Image processing device and method for blood flow imaging 有权
标题翻译：血流成像图像处理装置及方法
公开(公告)号：US08009885B2
公开(公告)日：2011-08-30
申请号：US11910477
申请日：2006-04-03
申请人： Michael Grass , Holger Schmitt
发明人： Michael Grass , Holger Schmitt
IPC分类号： G06K9/00 , A61B5/05
CPC分类号： G06T11/008 , G06T2211/404 , G06T2211/412
摘要： An image processing device is proposed and includes a reconstruction unit (51) for reconstruction of a 3D volume image of said object from said first series of X-ray projection images (D), a segmentation unit (52) for segmentation of the vessel tree from said 3D volume image, a forward projection unit (54) for forward projection of the segmented vessel tree onto said first and projection plane (R1, R2), respectively, and a mapping unit (55) for mapping of the image values of pixels of the vessel tree in said second and third, respectively, series of X-ray projection images onto corresponding voxels of said 3D volume image to obtain said time series of 3D volume images showing the blood flow in the vascular tree of the object.
摘要翻译：提出一种图像处理装置，包括：重建单元（51），用于从所述第一系列X射线投影图像（D）重建所述对象的3D体积图像;分割单元（52），用于分割血管树从所述3D体积图像中分别将分段血管树向前投影到所述第一和投影平面（R1，R2）上的前向投影单元（54）和用于映射像素的图像值的映射单元（55）分别将所述第二和第三的容器树的一系列X射线投影图像输送到所述3D体积图像的相应体素上，以获得所述时间序列的3D体积图像，其显示所述对象的血管树中的血流。

12. 发明授权

US06823204B2 Method of imaging the blood flow in a vascular tree 失效
标题翻译：在血管树中血流成像的方法
公开(公告)号：US06823204B2
公开(公告)日：2004-11-23
申请号：US10221240
申请日：2002-09-09
申请人： Michael Grass , Holger Schmitt , Volker Rasche
发明人： Michael Grass , Holger Schmitt , Volker Rasche
IPC分类号： A61B505
CPC分类号： A61B6/481 , A61B6/4014 , A61B6/504 , A61B6/507 , G06T17/00
摘要： The invention relates to a method of imaging a vascular tree that yields additional information concerning the vascular tree. To this end, a sequence of clusters is determined from spatially coherent voxels in the three-dimensional image of the vascular tree, the sequence of said clusters corresponding to the flow direction of the blood or the contrast medium in said vascular tree.
摘要翻译：本发明涉及一种对血管树进行成像的方法，其产生关于血管树的附加信息。为此，从血管树的三维图像中的空间相干体素确定簇序列，所述簇的序列对应于所述血管树中的血液或造影剂的流动方向。

13. 发明授权

US09597042B2 Perfusion imaging 有权
公开(公告)号：US09597042B2
公开(公告)日：2017-03-21
申请号：US13266556
申请日：2010-04-09
申请人： Roland Proksa , Michael Grass
发明人： Roland Proksa , Michael Grass
IPC分类号： G06K9/00 , A61B6/03 , A61B6/00
CPC分类号： A61B6/032 , A61B6/481 , A61B6/482 , A61B6/486 , A61B6/504 , A61B6/507
摘要： A method is disclosed that includes decomposing, with a decomposer, agent-based time series projection data for an object or a subject into at least an agent based component. A projection data decomposer includes a time series decomposer that determines agent-based projection data based on agent-based time series projection data based on at least two energy dependent components. A computer readable storage medium containing instructions which, when executed by a computer, cause the computer to perform the act of determining an agent-based component of agent-based time series projection data utilizing at least two components of the agent-based time series projection is provided.

14. 发明申请

US20160009898A1 ISONONYL ESTERS BASED ON FATTY ACIDS OR FATTY ACID MIXTURES FROM TALL OIL OR LINSEED OIL 审中-公开
标题翻译：基于脂肪酸或脂肪酸混合物的来自石油或林油的异烟肼
公开(公告)号：US20160009898A1
公开(公告)日：2016-01-14
申请号：US14773649
申请日：2014-02-14
申请人： Benjamin Woldt , Michael Grass , Andreas Gevers
发明人： Benjamin Woldt , Michael Grass , Andreas Gevers
IPC分类号： C08K5/1515 , C07D303/16 , C07D407/06
CPC分类号： C08K5/1515 , C07D303/16 , C07D407/06 , C08K5/101 , C08L27/06
摘要： The invention relates to an isononyl ester or isononyl ester mixture of an epoxidized fatty acid or an epoxidized fatty acid mixture, the fatty acid or fatty acid mixture being extracted from tall oil or linseed oil and the average number of epoxide groups per fatty acid being greater than 1.00.
摘要翻译：本发明涉及环氧化脂肪酸或环氧化脂肪酸混合物的异壬酯或异壬基酯混合物，脂肪酸或脂肪酸混合物由妥尔油或亚麻子油提取，每个脂肪酸的平均环氧基数大于超过1.00。

15. 发明授权

US09087404B2 Reconstruction for cone-beam computed tomography imaging with off-center flat panel detector 有权
标题翻译：用偏心平板检测器进行锥束计算机断层扫描成像的重建
公开(公告)号：US09087404B2
公开(公告)日：2015-07-21
申请号：US13697445
申请日：2011-04-25
申请人： Eberhard S. Hansis , Dirk Schaefer , Michael Grass
发明人： Eberhard S. Hansis , Dirk Schaefer , Michael Grass
IPC分类号： G01N23/04 , G06T1/00 , G06T11/00
CPC分类号： G06T11/008 , G06T11/006 , G06T2211/432
摘要： Computed tomography (CT) reconstruction includes reconstructing an axially extended reconstructed image from a measured cone beam x-ray projection data set (Pm), optionally having an off-center geometry. The reconstructing is performed for an extended volume (eFOV) comprising a reconstructable volume (rFOV) of the measured cone beam x ray data set that is extended along the axial direction. The projection data set may be weighted in the volume domain. Iterative reconstruction may be used, including initializing a constant volume and performing one or more iterations employing a first iterative update followed by one or more iterations employing a second, different iterative update. Alternatively, backprojection filtration (BPF) reconstruction may be used, including transforming the projection data set to a new geometry including finite differences between neighboring projection views and performing BPF using Hilbert filtering along a plurality of different directions and averaging the resultant reconstructed images to generate the final reconstructed image.
摘要翻译：计算机断层摄影（CT）重建包括从测量的锥形束X射线投影数据集（Pm）重建轴向延伸的重建图像，可选地具有偏心几何。对包括沿轴向延伸的测量的锥形束x射线数据集的可重建体积（rFOV）的扩展体积（eFOV）进行重建。投影数据集可以在体积域中加权。可以使用迭代重建，包括初始化恒定体积并且使用第一迭代更新执行一个或多个迭代，随后使用第二，不同迭代更新的一个或多个迭代。或者，可以使用反投影过滤（BPF）重建，包括将投影数据集变换为包括相邻投影视图之间的有限差异的新几何，并且使用沿着多个不同方向的希尔伯特滤波来执行BPF，并平均所得到的重建图像以产生最终重建图像。

16. 发明授权

US09002089B2 Image data registration for dynamic perfusion CT 有权
标题翻译：用于动态灌注CT的图像数据注册
公开(公告)号：US09002089B2
公开(公告)日：2015-04-07
申请号：US13643167
申请日：2011-04-12
申请人： Michael Grass , Alfonso Agatino Isola
发明人： Michael Grass , Alfonso Agatino Isola
IPC分类号： G06K9/00 , G06T7/00 , A61B6/00
CPC分类号： G06T7/0026 , A61B6/507 , G06T7/32 , G06T2207/10076 , G06T2207/30104
摘要： A method of registering a 4D contrast enhanced image data set, wherein the 4D contrast enhanced image data set includes image data of the same volume of interest acquired at different timeframes with changing contrast enhancement, the volume of interest includes moving structure, and the different timeframes correspond to a predetermined motion phase of interest in different motion cycles of the moving structure, the method, comprising: registering image data corresponding to a plurality of the different timeframes with reference image from one of the timeframes.
摘要翻译：一种注册4D对比度增强图像数据集的方法，其中所述4D对比度增强图像数据集包括在改变对比度增强的不同时间帧处获取的相同感兴趣体积的图像数据，所述感兴趣的体积包括移动结构和不同的时间帧对应于移动结构的不同运动周期中的感兴趣的预定运动相位，该方法包括：将与多个不同时间帧对应的图像数据与来自其中一个时间帧的参考图像进行对应。

17. 发明申请

US20150018576A1 METHOD AND DEVICE FOR THE HYDROFORMYLATION OF ISOBUTENE AND FOR THE SEPARATION OF THE PRODUCT MIXTURE 有权
标题翻译：用于分离产品混合物的方法和装置
公开(公告)号：US20150018576A1
公开(公告)日：2015-01-15
申请号：US14380647
申请日：2013-02-11
申请人： Goetz Baumgarten , Michael Grass , Alfred Kaizik , Markus Winterberg , Hans-Gerd Lueken , Bart Hamers , Markus Priske , Dirk Fridag , Robert Franke , Dieter Hess
发明人： Goetz Baumgarten , Michael Grass , Alfred Kaizik , Markus Winterberg , Hans-Gerd Lueken , Bart Hamers , Markus Priske , Dirk Fridag , Robert Franke , Dieter Hess
IPC分类号： C07C51/43 , C07C51/235 , C07C45/78 , C07C45/50
CPC分类号： C07C51/43 , B01D61/027 , C07C45/50 , C07C45/505 , C07C45/786 , C07C45/82 , C07C51/235 , C07C47/02
摘要： The invention relates to a method for producing a product mixture (2) by means of the technical hydroformylation of a hydrocarbon stream (1) that contains isobutene, and for separating the product mixture (2) that is obtained, as well as to a device for the claimed method and to the use of a claimed device. The problem addressed thereby is that of providing a method and an associated device that allow the amount of high-boiling substances in the product mixture (2) to be kept as low as possible and thus the yield of the reaction to be increased. The problem is solved by the use of a nano-filtration device (M) for separating the catalyst from the product mixture (2), said device having especially high permeability to 3-methylbutanoic acid.
摘要翻译：本发明涉及一种通过含有异丁烯的烃流（1）的技术加氢甲酰化以及用于分离获得的产物混合物（2）以及制备产物混合物（2）的方法，用于所要求保护的方法和所要求保护的装置的使用。由此提出的问题是提供一种方法和相关联的装置，其允许将产物混合物（2）中的高沸点物质的量保持尽可能低，从而提高反应的产率。通过使用纳米过滤装置（M）从产物混合物（2）中分离催化剂来解决该问题，所述装置对3-甲基丁酸具有特别高的渗透性。

18. 发明申请

US20140088226A1 DIANHYDROHEXITOL DIESTERS OF 2-ETHYLHEPTANOIC ACID 审中-公开
标题翻译：二乙二醇酸的二氢呋喃糖醇
公开(公告)号：US20140088226A1
公开(公告)日：2014-03-27
申请号：US14119994
申请日：2012-04-26
申请人： Andreas Gevers , Hinnerk Becker , Michael Grass , Markus Winterberg , Dietrich Maschmeyer , Christian Boeing
发明人： Andreas Gevers , Hinnerk Becker , Michael Grass , Markus Winterberg , Dietrich Maschmeyer , Christian Boeing
IPC分类号： C08K5/1535
CPC分类号： C08K5/1535 , C07D493/04 , C08K5/0016 , C08L27/06
摘要： Dianhydrohexitol diesters of 2-ethylheptanoic acid
摘要翻译： 2-乙基庚酸的二氢己糖二酯

19. 发明申请

US20130317153A1 DIISONONYL TEREPHTHALATE (DINT) AS SOFTENER FOR THERMOPLASTIC APPLICATIONS 审中-公开
标题翻译：作为热塑性应用的辅助剂的二硝基苯乙烯（DITONONYL TEREPHTHALATE（DINT）
公开(公告)号：US20130317153A1
公开(公告)日：2013-11-28
申请号：US13989422
申请日：2011-10-31
申请人： Michael Grass , Hinnerk Gordon Becker
发明人： Michael Grass , Hinnerk Gordon Becker
IPC分类号： C08K5/12 , C08K3/26
CPC分类号： C08K3/26 , C08K5/12
摘要： The present invention relates to the use of diisononyl terephthalate (DINT) as plasticizer for enhancing the low-temperature flexibilization and/or for enhancing the permanence in polymer compositions for thermoplastic applications.
摘要翻译：本发明涉及对苯二甲酸二异壬酯（DINT）作为增塑剂用于增强低温柔韧性和/或提高热塑性应用的聚合物组合物的耐久性的用途。

20. 发明授权

US08586784B2 Method for continuous catalytic hydrogenation 有权
标题翻译：连续催化氢化方法
公开(公告)号：US08586784B2
公开(公告)日：2013-11-19
申请号：US11320409
申请日：2005-12-29
申请人： Michael Grass , Burkhard Reeken , Axel Tuchlenski , Alfred Kaizik
发明人： Michael Grass , Burkhard Reeken , Axel Tuchlenski , Alfred Kaizik
IPC分类号： C07C61/00
CPC分类号： C07C67/303 , Y02P20/582 , C07C69/75
摘要： The invention relates to the preparation of alicyclic carboxylic acids or their derivatives by selective hydrogenation of the corresponding aromatic carboxylic acid (derivatives) in at least two series-connected reactors, at least one reactor being operated in loop operating mode. The catalyst volumes in the method are set in such a manner that the catalyst volume required, based on the conversion rate, is as low as possible.
摘要翻译：本发明涉及通过在至少两个串联连接的反应器中选择性氢化相应的芳族羧酸（衍生物）来制备脂环族羧酸或其衍生物，至少一个反应器以循环操作模式操作。该方法中的催化剂体积设定为使得基于转化率所需的催化剂体积尽可能低。

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