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11. 发明授权

US5312454A Apparatus and method of automatically adjusting a sensor signal comparator threshold for an oxygen sensing pacemaker 失效
标题翻译：自动调节氧气感应起搏器的传感器信号比较器阈值的装置和方法
公开(公告)号：US5312454A
公开(公告)日：1994-05-17
申请号：US947859
申请日：1992-12-14
申请人： Glenn M. Roline , Dennis A. Brumwell
发明人： Glenn M. Roline , Dennis A. Brumwell
IPC分类号： A61N1/365 , A61N1/36
CPC分类号： A61N1/36557
摘要： A monitoring system for an oxygen sensing, dual-wavelength, reflectance oximetry based, rate responsive cardiac pacemaker, is capable of automatically and continually adjusting an oxygen sensor signal comparator threshold such that the effects of noise, sensitivity and drift on oximeter output signals sent to the pacemaker are minimized. A comparator and related circuitry are configured to sample and compare supply excitations for multiple oxygen sensor light sources. The comparator threshold is adjusted as a function of supply excitation for each light source independently of one another, thereby providing an oxygen sensing pacemaker with optimal noise immunity since one of the more vulnerable portions of the pacing system is the transfer of the light source signals which are susceptible to noise.
摘要翻译：一种用于氧气感测双波长，基于反射率血糖测定法的速率响应心脏起搏器的监测系统能够自动和连续地调节氧传感器信号比较器阈值，使得噪声，灵敏度和漂移对血氧计输出信号的影响被发送到起搏器最小化。比较器和相关电路被配置为对多个氧传感器光源的电源激励进行采样和比较。比较器阈值作为每个光源的供应激励的函数被彼此独立地调整，从而提供具有最佳抗噪声能力的氧感应起搏器，因为起搏系统的较脆弱部分之一是光源信号的传送，容易受到噪音的影响。

12. 发明授权

US5129393A Dual chamber rate responsive pacemaker with variable refractory period 失效
$Dual chamber rate responsive pacemaker with variable refractory period$
标题翻译：具有可变耐用期的双层反应堆
公开(公告)号：US5129393A
公开(公告)日：1992-07-14
申请号：US567433
申请日：1990-08-14
申请人： Dennis A. Brumwell
发明人： Dennis A. Brumwell
IPC分类号： A61N1/362 , A61N1/365
CPC分类号： A61N1/365 , A61N1/3622
摘要： An improved atrial synchronous, dual chamber pacemaker provided with a variable refractory period during which the pacemaker is not responsive to the sensed atrial contractions. The atrial refractory period is varied as a function of measured atrial and ventricular rates, and corresponds to a predetermined proportion of the lesser of the average interval separating the ventricular contractions and the average interval separating atrial contractions. The invention is particularly beneficial in the context of a VDD type pacemaker.
摘要翻译：改进的心房同步双室心脏起搏器，其具有可变不应期，在此期间起搏器不能对感觉到的心房收缩作出反应。心房不应期作为测量的心房和心室率的函数而变化，并且对应于分离心室收缩的平均间隔和分离心房收缩的平均间隔中较小的预定比例。本发明在VDD型心脏起搏器的上下文中是特别有益的。

13. 发明授权

US4485813A Implantable dynamic pressure transducer system 失效
标题翻译：植入式动态压力传感器系统
公开(公告)号：US4485813A
公开(公告)日：1984-12-04
申请号：US322814
申请日：1981-11-19
申请人： Kenneth M. Anderson , Dennis A. Brumwell
发明人： Kenneth M. Anderson , Dennis A. Brumwell
IPC分类号： A61B5/0215 , A61N1/05 , A61N1/365 , A61B5/02
CPC分类号： A61B5/0215 , A61N1/056 , A61N1/36564
摘要： Pressure and motion transducer, and cooperating circuitry for an implantable medical device is disclosed. The system includes a clock for the pulse excitation of a dynamic motion transducer and further includes circuitry for recovering the modulated signal from the transducer.
摘要翻译：公开了用于可植入医疗装置的压力和运动传感器以及协作电路。该系统包括用于动态运动换能器的脉冲激励的时钟，并且还包括用于从换能器恢复调制信号的电路。

14. 发明授权

US4903701A Oxygen sensing pacemaker 失效
标题翻译：氧气感应起搏器
公开(公告)号：US4903701A
公开(公告)日：1990-02-27
申请号：US166591
申请日：1988-03-10
申请人： Alan A. Moore , Dennis A. Brumwell
发明人： Alan A. Moore , Dennis A. Brumwell
IPC分类号： A61B5/00 , A61N1/365
CPC分类号： A61N1/36557 , A61B5/1459
摘要： A demand pacemaker which regulates its pacing rate based upon sensed oxygen saturation percentage. The pacemaker employs a two wavelength reflectance oximeter as a sensor. The sensor includes an oscillator which sequentially activates red and infrared diodes. The duty cycle of the oscillator is regulated by the relative amounts of red and infrared light reflected by the blood. The construction of the sensor allows the sensor to operate with only two conductors, optimizing it for incorporation in a standard, bipolar pacing lead.
摘要翻译：根据检测到的氧饱和度百分比调节其起搏速度的需求起搏器。起搏器采用双波长反射式血氧计作为传感器。该传感器包括顺序激活红色和红外二极管的振荡器。振荡器的占空比由血液反射的红色和红外线的相对量来调节。传感器的结构允许传感器只使用两根导体，优化它，以纳入标准的双极起搏引线。

15. 发明授权

US4813421A Oxygen sensing pacemaker 失效
公开(公告)号：US4813421A
公开(公告)日：1989-03-21
申请号：US123457
申请日：1987-11-19
申请人： Michael D. Baudino , Michael D. De Franco , Joseph F. Lessar , Dennis A. Brumwell , Gene A. Bornzin , Jeffrey A. Schweitzer
发明人： Michael D. Baudino , Michael D. De Franco , Joseph F. Lessar , Dennis A. Brumwell , Gene A. Bornzin , Jeffrey A. Schweitzer
IPC分类号： A61N1/05 , A61N1/365 , A61B5/00
CPC分类号： A61N1/056 , A61N1/36557
摘要： A heart pacemaker including a two wave length reflectance oximeter for determining oxygen saturation. The pacing rate is increased or decreased in response to the measured oxygen saturation. By appropriate multiplexing and timing functions, the two wave length reflectance oximeter is included in a pacing lead coupled to the pacemaker which requires only three conductors.

16. 发明授权

US4807629A Oxygen sensing pacemaker 失效
标题翻译：氧气感应起搏器
公开(公告)号：US4807629A
公开(公告)日：1989-02-28
申请号：US122821
申请日：1987-11-19
申请人： Michael D. Baudino , Michael D. De Franco , Joseph F. Lessar , Dennis A. Brumwell , Gene A. Bornzin , Jeffrey A. Schweitzer
发明人： Michael D. Baudino , Michael D. De Franco , Joseph F. Lessar , Dennis A. Brumwell , Gene A. Bornzin , Jeffrey A. Schweitzer
IPC分类号： A61N1/05 , A61N1/365 , A61N1/00
CPC分类号： A61N1/056 , A61N1/36557
摘要： A heart pacemaker including a two wave length reflectance oximeter for determining oxygen saturation. The pacing rate is increased or decreased in response to the measured oxygen saturation. By appropriate multiplexing and timing functions, the two wave length reflectance oximeter is included in a pacing lead coupled to the pacemaker which requires only three conductors.
摘要翻译：一种心脏起搏器，包括用于确定氧饱和度的两个波长反射血氧计。响应于测量的氧饱和度，起搏速率增加或减少。通过适当的多路复用和定时功能，两个波长反射率血氧计包括在起搏器中的起搏引线，起搏器仅需要三个导体。

17. 发明授权

US4791935A Oxygen sensing pacemaker 失效
标题翻译：氧气感应起搏器
公开(公告)号：US4791935A
公开(公告)日：1988-12-20
申请号：US896695
申请日：1986-08-15
申请人： Michael D. Baudino , Michael D. de Franco , Joseph F. Lessar , Dennis A. Brumwell , Gene A. Bornzin , Jeffrey A. Schweitzer
发明人： Michael D. Baudino , Michael D. de Franco , Joseph F. Lessar , Dennis A. Brumwell , Gene A. Bornzin , Jeffrey A. Schweitzer
IPC分类号： A61N1/05 , A61N1/365 , A61N1/00
CPC分类号： A61N1/36557 , A61N1/056
摘要： A heart pacemaker including a two wave length reflectance oximeter for determining oxygen saturation. The pacing rate is increased or decreased in response to the measured oxygen saturation. By appropriate multiplexing and timing functions, the two wave length reflectance oximeter is included in a pacing lead coupled to the pacemaker which requires only three conductors.
摘要翻译：一种心脏起搏器，包括用于确定氧饱和度的两个波长反射血氧计。响应于测量的氧饱和度，起搏速率增加或减少。通过适当的多路复用和定时功能，两个波长反射率血氧计包括在起搏器中的起搏引线，起搏器仅需要三个导体。

18. 发明授权

US4750495A Oxygen sensing pacemaker 失效
标题翻译：氧气感应起搏器
公开(公告)号：US4750495A
公开(公告)日：1988-06-14
申请号：US58300
申请日：1987-06-05
申请人： Alan A. Moore , Dennis A. Brumwell
发明人： Alan A. Moore , Dennis A. Brumwell
IPC分类号： A61B5/00 , A61N1/365 , A61N1/36
CPC分类号： A61B5/1459 , A61N1/36557
摘要： A demand pacemaker which regulates its pacing rate based upon sensed oxygen saturation percentage. The pacemaker employs a two wavelength reflectance oximeter as a sensor. The sensor includes an oscillator which sequentially activates red and infrared diodes. The duty cycle of the oscillator is regulated by the relative amounts of red and infrared light reflected by the blood. The construction of the sensor allows the sensor to operate with only two conductors, optimizing it for incorporation in a standard, bipolar pacing lead.

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