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11. 发明授权

US5951967A Multi-phase light screening agent, process for its production and for its application to the skin 失效
标题翻译：多相光屏蔽剂，其生产工艺及其在皮肤上的应用
公开(公告)号：US5951967A
公开(公告)日：1999-09-14
申请号：US973605
申请日：1998-01-28
申请人： Karin Golz , Leonhard Zastrow , Klaus Stanzl , Jacques Gerbron , Louis Ferrero
发明人： Karin Golz , Leonhard Zastrow , Klaus Stanzl , Jacques Gerbron , Louis Ferrero
IPC分类号： A61K8/00 , A61K8/03 , A61K8/25 , A61K8/26 , A61K8/29 , A61K8/33 , A61K8/34 , A61K8/35 , A61K8/37 , A61K8/41 , A61K8/46 , A61K8/97 , A61K8/98 , A61Q17/04 , A61K7/42 , A61K7/00 , A61K7/44
CPC分类号： A61K8/03 , A61Q17/04
摘要： A multi-phase sunscreen agent, characterized by at least two phases that are liquid to pasty or gelatinous and separate from each other spontaneously within seconds to less than ten minutes after a brief and gentle mixing process lasting less than one minute without any essential application of force, where at least one phase contains a UV filter.
摘要翻译： PCT No.PCT / DE96 / 01046 Sec。 371日期1998年1月28日 102（e）1998年1月28日PCT PCT 1996年6月7日PCT公布。公开号WO96 / 41613 日期：1996年12月27日一种多相防晒剂，其特征在于至少两相是液体糊状或凝胶状，并且在持续不到一分钟的短暂且温和的混合过程之后，在数秒至少于十分钟内自发分离没有任何基本的施加力，其中至少一个相包含UV过滤器。

12. 发明授权

US5800835A Preparation for improving the blood supply containing hard magnetic particles 失效
标题翻译：用于改善含有硬磁性颗粒的血液供应的准备
公开(公告)号：US5800835A
公开(公告)日：1998-09-01
申请号：US522304
申请日：1995-09-05
申请人： Leonhard Zastrow , Dagmar Hulsenberg , Karin Golz , Klaus Stanzl
发明人： Leonhard Zastrow , Dagmar Hulsenberg , Karin Golz , Klaus Stanzl
IPC分类号： A61K8/19 , A61K8/34 , A61K9/127 , A61K31/715 , A61K33/26 , A61N1/40 , A61N2/08 , A61P9/00 , A61Q1/00 , A61Q1/04 , A61Q5/00 , A61Q5/02 , A61Q7/00 , A61Q19/00
CPC分类号： A61N1/406 , A61K33/26 , A61K8/0212 , A61K8/19 , A61K9/127 , A61Q19/00 , A61Q7/00 , A61K2800/47 , A61Q1/02 , A61Q1/06 , A61Q1/12 , A61Q17/04 , A61Q19/10 , A61Q5/00 , A61Q5/02
摘要： The invention relates to a preparation for improving the blood supply. The problem with prior art preparations or processes resides in the fact that soft magnetic components had to be introduced into the body in capsule form or a magnetic field had to be applied after the application of demagnetized particles to the skin. The purpose of the invention is to provide a novel preparation for improving the blood supply in which special hard magnetic particles are used. According to the invention, the preparation for improving the blood supply consists of a pharmaceutically or cosmetically acceptable medium and possibly further additives containing finely distributed hard magnetic single-grade particles with a high coercitive field intensity and grain sizes in the range of 600 to 1200 nm. Dispersions of this preparation exhibit no aggregation of the hard magnetic particles. The preferred use is in the cosmetic and dermatological field.
摘要翻译： PCT No.PCT / DE94 / 00879 Sec。 371 1995年9月5日第 102（e）1995年9月5日PCT PCT 1994年7月19日PCT公布。第WO95 / 03061号公报日期1995年2月2日本发明涉及一种改善血液供应的制剂。现有技术的制备或方法的问题在于，软磁性组分必须以胶囊形式引入体内，或者在将去磁颗粒施加到皮肤之后必须施加磁场。本发明的目的是提供一种用于改善使用特殊硬磁性颗粒的血液供应的新型制剂。根据本发明，用于改善血液供应的制剂由药学或化妆品可接受的培养基组成，并且可能还有其它添加剂，其含有具有高矫顽磁场强度的精细分布的硬磁单级颗粒，并且在600至1200nm范围内的晶粒尺寸。该制剂的分散体不显示硬磁性颗粒的聚集。优选的用途是在化妆品和皮肤病领域。

13. 发明授权

US5976510A Cosmetic tanning and sunscreen agent 失效
标题翻译：化妆品鞣制和防晒剂
公开(公告)号：US5976510A
公开(公告)日：1999-11-02
申请号：US951703
申请日：1997-10-16
申请人： Domnica Cernasov , Ralph Maccio , Klaus Stanzl , Leonhard Zastrow , Rupali Kulkarni
发明人： Domnica Cernasov , Ralph Maccio , Klaus Stanzl , Leonhard Zastrow , Rupali Kulkarni
IPC分类号： A61K8/06 , A61K8/19 , A61K8/29 , A61K8/69 , A61K8/81 , A61K8/891 , A61K8/894 , A61K8/898 , A61Q17/04 , A61K7/42 , A61K7/00
CPC分类号： A61K8/894 , A61K8/06 , A61K8/062 , A61K8/19 , A61K8/29 , A61K8/55 , A61K8/69 , A61K8/81 , A61K8/891 , A61Q17/04 , A61K2800/43
摘要： A new cosmetic product combines tanning, sunscreen, moisturizing and water-repellant properties in a stable formulation. The product is an O/W emulsion which includes from 5% to 14% by weight of inorganic pigments treated with perfluoroalkyl phosphates, in which the pigments are selected from the group consisting of colored iron oxides, titanium dioxide and mixtures thereof. There are dispersants selected from the group consisting of at least (b1) cetyl dimethicone copolyol and (b2) cetyl dimethicone which are present in the range of 2% to 10% by weight, with the ratio of (b1) to (b2) in the range from 15-3 to 40-8, and further known carrier and auxiliary agents as well as further dispersants if required, in which the share of moisturizing additives is less than 4% by weight.
摘要翻译：新的化妆品在稳定的配方中结合了鞣制，防晒，保湿和防水性能。该产品是O / W乳液，其包含5重量％至14重量％的用全氟烷基磷酸酯处理的无机颜料，其中颜料选自有色氧化铁，二氧化钛及其混合物。存在分散剂，其选自至少（b1）十六烷基二甲基硅氧烷共聚多元醇和（b2）十六烷基二甲基硅油，其存在量为2重量％至10重量％，其中（b1）与（b2）的比率范围从15-3至40-8，以及进一步已知的载体和助剂以及需要的其它分散剂，其中保湿添加剂的份额小于4重量％。

14. 发明授权

US5885564A Functional oxygenated composition containing phospholipids and fluorocarbon 失效
标题翻译：含有磷脂和碳氟化合物的功能含氧组合物
公开(公告)号：US5885564A
公开(公告)日：1999-03-23
申请号：US877040
申请日：1997-06-17
申请人： Leonhard Zastrow , Karin Golz , Klaus Stanzl
发明人： Leonhard Zastrow , Karin Golz , Klaus Stanzl
IPC分类号： A61K8/70 , A61K8/99 , A61K9/133 , A61K36/886 , A61Q19/00 , A61K35/72 , A61K35/74
CPC分类号： A61K8/22 , A61K8/553 , A61K8/70 , A61K8/99 , A61Q19/00
摘要： A composition contains certain nutrients, active and protective substances, as well as an oxygen carrier, along with a process for preparing this composition and its use. The composition provides skin care preparation with a high oxygen content which also contain further nutrients, active and/or protective substances. The new functional oxygenated composition contains (a) phospholipids and oxygen-loaded fluorocarbon or fluorocarbon mixtures. The proportion of fluorocarbon lies in the 0.2 to 100% by weight/volume range. The lipid fraction contains 30 to 99% by weight phosphatidylcholine in the form of asymmetric lamellar aggregates. The composition also contains (b) a product obtained by gentle disintegration of suspensions or dispersions of cells of plant substances, bacteria or yeasts by ultrasonic and/or high-pressure homogenization under up to 25 MPa; and (c) a cosmetic or dermatological carrier suitable for use on the skin. This composition is based for its oxygen content on the synergy between fluorocarbons and the disintegration products.
摘要翻译：组合物含有某些营养物质，活性和保护物质以及氧气载体，以及制备该组合物及其用途的方法。该组合物提供具有高氧含量的皮肤护理制剂，其还含有进一步的营养物质，活性和/或保护性物质。新的功能性氧合组合物包含（a）磷脂和含氧碳氟化合物或碳氟化合物混合物。碳氟化合物的比例在0.2至100重量％/体积范围内。脂质部分含有30至99重量％的非对称层状聚集体形式的磷脂酰胆碱。该组合物还含有（b）通过在高达25MPa下通过超声波和/或高压均质化将植物物质，细菌或酵母细胞的悬浮液或分散体温和分解得到的产物; 和（c）适合在皮肤上使用的化妆品或皮肤病学载体。该组合物是基于碳氟化合物和崩解产物之间的协同作用的氧含量。

15. 发明授权

US6106847A Stable multiple phase emulsion of the type O.sub.1 /W/O.sub.2 失效
标题翻译： O1 / W / O2型稳定型多相乳液
公开(公告)号：US6106847A
公开(公告)日：2000-08-22
申请号：US924241
申请日：1997-09-05
申请人： Louis Ferrero , Karin Golz , Leonhard Zastrow , Klaus Stanzl
发明人： Louis Ferrero , Karin Golz , Leonhard Zastrow , Klaus Stanzl
IPC分类号： A61K8/06 , A61Q17/04 , A61K7/48
CPC分类号： A61Q17/04 , A61K8/066 , Y10S514/937 , Y10S514/938
摘要： The invention relates to a stable multiple phase emulsion of the O.sub.1 /W/O.sub.2 type with high proportions of the primary O.sub.1 /W emulsion. The new emulsions have an emulsifier-free primary oil-in-water phase consisting of a viscoplastic aqueous gel containing the finely distributed inner oil droplets together with a gelling agent, wherein the thixotropic primary oil-in-water phase has a yield point in the range from 20 to 100 Pa and a plastic viscosity of 0.01 to 0.1 Pa.multidot.s and contains at least one lipophilic agent in the primary oil; and a secondary oil phase in which the primary oil-in-water phase is present together with a lipophilic emulsifier; and wherein the proportion of the inner oily phase is from 10 to 35 % by weight relative to the total weight of the emulsion. The higher proportions of the inner oily phase render possible higher proportions of organic sun protection agents with simultaneous avoidance of skin irritations.
摘要翻译：本发明涉及具有高比例的主要O1 / W乳液的O1 / W / O2型稳定的多相乳液。新的乳液具有不含乳化剂的初级水包油相，其由含有细分散的内部油滴的胶粘剂水凝胶与胶凝剂组成，其中触变性初级水包油相具有屈服点范围为20〜100Pa，塑性粘度为0.01〜0.1Pax，在原油中含有至少一种亲脂性试剂; 和主要油包水相与亲脂性乳化剂一起存在的次级油相; 并且其中所述内部油相的比例相对于所述乳液的总重量为10至35重量％。内部油相的比例越高，可以提供更高比例的有机防晒剂，同时避免皮肤刺激。

16. 发明授权

US5919490A Preparation for improving the blood supply containing hard magnetic particles 失效
标题翻译：用于改善含有硬磁性颗粒的血液供应的准备
公开(公告)号：US5919490A
公开(公告)日：1999-07-06
申请号：US951701
申请日：1997-10-16
申请人： Leonhard Zastrow , Dagmar Hulsenberg , Karin Golz , Klaus Stanzl
发明人： Leonhard Zastrow , Dagmar Hulsenberg , Karin Golz , Klaus Stanzl
IPC分类号： A61K8/19 , A61K8/34 , A61K9/127 , A61K31/715 , A61K33/26 , A61N1/40 , A61N2/08 , A61P9/00 , A61Q1/00 , A61Q1/04 , A61Q5/00 , A61Q5/02 , A61Q7/00 , A61Q19/00
CPC分类号： A61N1/406 , A61K33/26 , A61K8/0212 , A61K8/19 , A61K9/127 , A61Q19/00 , A61Q7/00 , A61K2800/47 , A61Q1/02 , A61Q1/06 , A61Q1/12 , A61Q17/04 , A61Q19/10 , A61Q5/00 , A61Q5/02
摘要： A preparation for stimulating the blood circulation of the skin comprising a dispersion containing a proportion of finely divided magnetically hard single-domain particles in the dispersion being in the range from 0.01% to 70% by weight, based on the total weight of the dispersion; these particles having a strong coercive field and being in the range 600 to 1200 nm; and the magnetically hard single-domain particles are selected from the group consisting of barium hexaferrite, strontium hexaferrite, undoped barium hexaferrite, undoped strontium hexaferrite, and the mixtures thereof; and the balance up to 100% by weight of a cosmetic or pharmaceutical excipient carrier substance or a pharmaceutical additive, based on the total weight of the dispersion.
摘要翻译：一种用于刺激皮肤血液循环的制剂，其包含在分散体中含有一部分细分散的磁性硬单域结构域颗粒的分散体，基于分散体的总重量为0.01重量％至70重量％; 这些颗粒具有强矫顽磁场并且在600至1200nm的范围内; 并且磁性硬单畴颗粒选自六硼酸钡，六硼酸锶，未掺杂的六硼酸钡，未掺杂六氟合锶及其混合物; 以及基于分散体的总重量的至多100重量％的化妆品或药物赋形剂载体物质或药物添加剂的平衡物。

17. 发明授权

US5916577A Cosmetic with condensates of plant and animal decomposition products 失效
标题翻译：化妆品与植物和动物分解产物的冷凝物
公开(公告)号：US5916577A
公开(公告)日：1999-06-29
申请号：US875798
申请日：1997-07-18
申请人： Karin Golz , Leonhard Zastrow , Klaus Stanzl , Ulrich Klugel , Gunter Westphal , Leander Schobel
发明人： Karin Golz , Leonhard Zastrow , Klaus Stanzl , Ulrich Klugel , Gunter Westphal , Leander Schobel
IPC分类号： A61K8/02 , A61K8/73 , A61K8/97 , A61K8/98 , A61K8/99 , A61K36/752 , A61K36/87 , A61Q5/02 , A61Q5/12 , A61Q19/00 , A61K35/78 , A61K7/06 , A61K7/48 , A61K35/20
CPC分类号： A61Q19/00 , A61K8/0212 , A61K8/732 , A61K8/975 , A61K8/986 , A61K8/99 , A61Q5/02 , A61Q5/12
摘要： The invention concerns cosmetic agents with condensates of plant and animal decomposition products, which can be used in cosmetic body care and cleansing preparations and which, in addition to the emulsifying effect, have essential skin-care properties. The object of the invention is to prepare cosmetic products from plant and animal starting materials, said products having substantial portions of original biological structures but being modified to such an extent that they are cosmetically acceptable owing to their neutral smell and pale color. According to the invention, the cosmetic agent is a product of a direct and mild (20 to 55.degree. C.; pH 7.5 to 8.5) decomposition of a biological starting material in an aqueous medium, subsequent condensation with a sub-stoechiometric amount of a C.sub.10 to C.sub.20 fatty acid halide or mixture and optionally subsequent etherification or esterification of the condensation product. The starting materials can be yeasts, yeast fractions, pulses, pulse fractions, pectins, pectin-containing masses, algae, algae fractions, animal milk, animal milk fractions and their mixtures, and contain helical natural substance components, enzyme structures and vitamin structures.
摘要翻译： PCT No.PCT / DE96 / 00548 Sec。 371日期1997年7月17日 102（e）日期1997年7月17日PCT 1996年3月22日PCT公布。出版物WO96 / 29048 日期1996年9月26日本发明涉及具有植物和动物分解产物的缩合物的化妆品，其可用于化妆品身体护理和清洁制剂中，并且除了乳化作用之外，还具有必需的皮肤护理性质。本发明的目的是从植物和动物原料制备化妆品，所述产品具有原始生物结构的大部分，但是被改性到由于其中性气味和浅色而使其成为美容上可接受的程度。根据本发明，化妆品是水性介质中直接和温和（20至55℃; pH 7.5至8.5）分解生物原料的产物，随后与亚化学量的 C10至C20脂肪酸卤化物或混合物，以及随后的缩合产物醚化或酯化。起始原料可以是酵母，酵母馏分，脉冲，脉冲级分，果胶，含果胶质量块，藻类，藻类部分，动物乳，动物乳馏分及其混合物，并含有螺旋天然物质组分，酶结构和维生素结构。

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