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11. 发明授权

US4891314A Agent for the determination of peroxidase activity, with stabilizer, a process for its preparation and its use 失效
标题翻译：用于测定过氧化物酶活性的试剂，具有稳定剂，其制备方法及其用途
公开(公告)号：US4891314A
公开(公告)日：1990-01-02
申请号：US935332
申请日：1986-11-26
申请人： Hans E. Pauly , Herbert Schwarz
发明人： Hans E. Pauly , Herbert Schwarz
IPC分类号： G01N33/535 , C12Q1/26 , C12Q1/28 , G01N33/72
CPC分类号： G01N33/725 , C12Q1/28 , C12Q2326/12 , Y10S436/904
摘要： An agent for the detection of peroxidase or of pseudoperoxidase activity, and its preparation and its use are described. The agent contains a tetraalkylbenzidine, a penicillin, or its breakdown products obtained by acid hydrolysis, as stabilizer,a peroxide and buffer substances. The agent according to the invention has, as a peroxidase substrate, the advantage over previous tetraalkylbenzidine-containing substrates that it is stable on storage as solution for use, and produces a lower background coloration.
摘要翻译：描述了过氧化物酶或假过氧化物酶活性检测的试剂及其制备及其应用。该试剂含有四烷基联苯胺，青霉素或其通过酸水解获得的分解产物，作为稳定剂，过氧化物和缓冲物质。根据本发明的药剂具有作为过氧化物酶底物的优点，优于先前的含四烷基联苯胺的底物，其在作为溶液使用时作为溶液是稳定的，并且产生较低的背景着色。

12. 发明授权

US4067482A Dispensing and actuator cap for aerosol packages 失效
标题翻译：喷雾包装的分配和执行器盖
公开(公告)号：US4067482A
公开(公告)日：1978-01-10
申请号：US682669
申请日：1976-05-03
申请人： Gunter Vogel , Herbert Schwarz
发明人： Gunter Vogel , Herbert Schwarz
IPC分类号： B65D83/14 , B65D83/16
CPC分类号： B65D83/206 , B65D83/228
摘要： Dispensing cap for valves for aerosol containers, comprising a stationary body designed to be secured to the container and a dispensing push button which is designed to be connected to the actuating stem of the valve, wherein the body has a deformable portion which is hingedly or pivotally mounted on the remainder of the body at its two ends and which can be displaced inwards into the body for actuating the push button, and a frangible device which acts as a tamper-proofing device and which initially is connected first to the deformable portion of the body at at least two points lying on opposite sides of a hinge or pivotal connection of the deformable portion, and wherein the device, until the purchaser tears it off, prevents the deformable portion from being pressed inwards into the body.
摘要翻译：用于气溶胶容器的阀的分配盖，包括设计成固定到容器的固定体和设计成连接到阀的致动杆的分配按钮，其中主体具有可变形部分，其可铰接或枢转安装在其两端的身体的其余部分上，并且可以向内移动进入本体以致动按钮;以及易碎装置，其作为防篡改装置，并且其最初首先连接到所述可变形部分本体在位于铰链的相对侧上的至少两个点处或可变形部分的枢转连接处，并且其中，在该购买者撕裂之前，该装置防止可变形部分向内压入本体。

13. 发明授权

US07951910B2 Peptides with the marburg I polymorphism of factor VII-activating protease (FSAP) and their preparation and uses 有权
标题翻译：多肽与Marburg I多态性因子VII活化蛋白酶（FSAP）及其制备和用途
公开(公告)号：US07951910B2
公开(公告)日：2011-05-31
申请号：US12578337
申请日：2009-10-13
申请人： Herbert Schwarz , Harald Althaus , Bodo Fischer , Thomas Wissel
发明人： Herbert Schwarz , Harald Althaus , Bodo Fischer , Thomas Wissel
IPC分类号： C07K14/745
CPC分类号： C07K16/40 , Y10S530/806
摘要： The invention relates to peptides with the Marburg I polymorphism of FSAP and to their preparation and uses, in particular in therapy and diagnosis. The peptides are suitable for use as immunizing antigens for preparing FSAP MR I specific antibodies.
摘要翻译：本发明涉及具有FSAP的Marburg I多态性的肽及其制备和用途，特别是在治疗和诊断中。这些肽适合用作免疫抗原来制备FSAP MR I特异性抗体。

14. 发明授权

US07943333B2 Diagnostic method for identifying carriers of the Marburg I variant of factor VII-activating protease (FSAP) on the basis of differential modulation of FSAP activity 有权
标题翻译：基于FSAP活性差异调节的鉴定因子VII活化蛋白酶（FSAP）的Marburg I变体载体的诊断方法
公开(公告)号：US07943333B2
公开(公告)日：2011-05-17
申请号：US11642747
申请日：2006-12-21
申请人： Frank Vitzthum , Herbert Schwarz
发明人： Frank Vitzthum , Herbert Schwarz
IPC分类号： C12Q1/37 , C12Q1/56 , G01N33/573 , G01N33/86
CPC分类号： G01N33/6893 , C12Q1/37 , C12Q1/56 , G01N33/86 , G01N2333/8117 , G01N2333/96447
摘要： The present invention relates to a diagnostic method for identifying persons with genetically related hetero- or homozygous expression of the MR I variant of factor VII-activating protease (FSAP). The heterozygous or homozygous presence of an MR I polymorphism can be identified by a differential modulation of the FSAP activity.
摘要翻译：本发明涉及用于识别因子VII活化蛋白酶（FSAP）的MRI变体的遗传相关杂合或纯合表达的人的诊断方法。可以通过FSAP活性的差异调制来鉴定MR I多态性的杂合或纯合存在。

15. 发明授权

US07274788B2 Mounting for electronic accessories for vehicles 失效
标题翻译：车载电子配件安装
公开(公告)号：US07274788B2
公开(公告)日：2007-09-25
申请号：US10496599
申请日：2002-11-26
申请人： Jochen Schanz , Herbert Schwarz
发明人： Jochen Schanz , Herbert Schwarz
IPC分类号： H04M1/00
CPC分类号： B60R11/02 , B60R11/0211 , B60R11/0241 , B60R11/0258 , B60R2011/0075 , B60R2011/0089 , B60R2011/0096
摘要： A mounting device for electronic accessories for vehicles has a mounting having a shape matched to the shape of an accessory to be received. A mechanical lock is connected to the mounting. The lock has a locking bar that engages a housing recess in the form of a groove or a housing edge of the accessory received in the mounting. The lock has a key for manual actuation of the lock by rotating the key in the lock and moving the locking bar in and out of engagement of the housing recess or the housing edge.
摘要翻译：用于车辆的电子配件的安装装置具有与待接收的附件的形状匹配的形状的安装。机械锁连接到安装座。锁具有锁定杆，该锁定杆以接收在安装件中的附件的凹槽或外壳边缘的形式接合壳体凹部。锁具有用于通过旋转锁中的钥匙并将锁定杆移动进入和离开壳体凹部或外壳边缘的接合来手动致动锁的钥匙。

16. 发明申请

US20060121030A1 Use of cd 137 antagonists for the treatment of tumors 审中-公开
标题翻译：使用cd 137拮抗剂治疗肿瘤
公开(公告)号：US20060121030A1
公开(公告)日：2006-06-08
申请号：US10539257
申请日：2003-12-16
申请人： Herbert Schwarz , Margarethe Wittmann
发明人： Herbert Schwarz , Margarethe Wittmann
IPC分类号： A61K48/00 , A61K39/395
CPC分类号： C07K16/2878 , A61K38/177 , A61K2039/505 , C07K2319/30 , C12N15/1138 , C12N2310/11 , C12N2310/14
摘要： The present invention relates to the therapy of tumors through neutralisation of CD137 or inhibition of CD137 expression of CD137 antagonising molecules. Furthermore, the present invention provides the use of CD137 or agonistic anti-CD307 ligand antibodies for the treatment of conditions characterised by overactive immune reactions.
摘要翻译：本发明涉及通过中和CD137或抑制CD137拮抗分子的CD137表达来治疗肿瘤。此外，本发明提供CD137或激动性抗-CD307配体抗体用于治疗以过度活动的免疫反应为特征的病症的用途。

17. 发明申请

US20050000988A1 Support for fixing auxiliary electronic appliances on two-wheelers 有权
标题翻译：支持在二轮车上固定辅助电子设备
公开(公告)号：US20050000988A1
公开(公告)日：2005-01-06
申请号：US10492304
申请日：2002-10-21
申请人： Jochen Schanz , Herbert Schwarz
发明人： Jochen Schanz , Herbert Schwarz
IPC分类号： B62J11/00 , B62J7/06
CPC分类号： B62J11/00
摘要： A support for attachment of auxiliary electronic devices on two-wheelers has a support member shaped to match an auxiliary electronic device to be inserted. An actuator is provided that has an actuator part and a locking pawl configured to lock the auxiliary device received in the support member. The actuator enables insertion and removal as well as securing of the auxiliary electronic device. A spring element acts on the actuator. The spring element is a spring steel sheet that is rotatable about a flexion point or an axis.
摘要翻译：辅助电子装置在两轮车上的安装支撑件具有支撑构件，其形状与要插入的辅助电子装置相匹配。提供了一种致动器，其具有致动器部分和锁定棘爪，该锁定爪构造成锁定容纳在支撑构件中的辅助装置。执行器能够插入和移除以及固定辅助电子设备。弹簧元件作用在致动器上。弹簧元件是能够围绕弯曲点或轴线旋转的弹簧钢板。

18. 发明授权

US4079090A Preparation of trichloromethyl-trifluoro methyl-benzenes 失效
标题翻译：三氯甲基 - 三氟甲基苯的制备
公开(公告)号：US4079090A
公开(公告)日：1978-03-14
申请号：US731478
申请日：1976-10-12
申请人： Gerhard Buttner , Erich Klauke , Herbert Schwarz , Fritz Doring
发明人： Gerhard Buttner , Erich Klauke , Herbert Schwarz , Fritz Doring
IPC分类号： B01J27/00 , C07B61/00 , C07C17/00 , C07C17/20 , C07C17/37 , C07C22/08 , C07C25/02 , C07C25/13 , C07C67/00 , C07C25/14
CPC分类号： C07C17/202
摘要： A process for preparing a xylene which is fluorinated and chlorinated in the side chain, having the formula ##STR1## wherein X represents hydrogen or fluorine andY represents hydrogen or chlorine andR.sup.1 and R.sup.2 are identical or different and represent hydrogen, halogen, a trifluoromethyl or trichloromethyl group or an aliphatic or aromatic radical andR.sup.1 and R.sup.2 can be bonded via hydrocarbon members to form an aromatic ring,By contacting a compound of the formula ##STR2## wherein X, R.sup.1 and R.sup.2 have the above-mentioned meanings, WITH A COMPOUND OF THE FORMULA ##STR3## wherein X, R.sup.1 and R.sup.2 have the above-mentioned meanings, in the presence of a halogen transfer catalyst at elevated temperature.
摘要翻译：一种制备在侧链中氟化和氯化的二甲苯的方法，其具有式（I）其中X表示氢或氟，Y表示氢或氯，并且R 1和R 2相同或不同，表示氢，卤素，三氟甲基或三氯甲基或脂族或芳族基团，R 1和R 2可以通过烃成员键合形成芳环。通过接触式（II）的化合物，其中X，R 1和R 2具有上述（III）的化合物，其中X，R 1和R 2具有上述含义，在卤素转移催化剂存在下在升高的温度下进行。

19. 发明授权

US3956089A Process for producing N-chlorocarbonyl isocyanide dichloride 失效
标题翻译：制备N-氯羰基异腈二氯化物的方法
公开(公告)号：US3956089A
公开(公告)日：1976-05-11
申请号：US544021
申请日：1975-01-24
申请人： Hermann Hagemann , Herbert Schwarz , Fritz Doring
发明人： Hermann Hagemann , Herbert Schwarz , Fritz Doring
IPC分类号： C07C271/00 , C07C20060101 , C07C67/00 , C07C239/00 , B01J1/10
摘要： N-chlorocarbonyl isocyanide dichloride is prepared by chlorinating methyl isocyanate and/or methyl carbamic acid chloride in solution in the presence of ultraviolet light at a temperature in the range of from 30.degree. to 120.degree.C. The temperature pattern during the reaction is controlled in relation to the concentration of methyl isocyanate in the reaction mixture such that low temperatures are maintained for high concentrations while high temperatures are maintained with low concentrations. Thus, when a temperature of from 30.degree.-40.degree.C is maintained during the reaction, the concentration of methyl isocyanate in the reaction mixture is substantially more than 50 percent; when the temperature is increased to 65.degree. to 75.degree.C, the concentration of methyl isocyanate is in the range of 50 percent to 10 percent; and when the temperature is increased above 75.degree.C, the concentration of methyl isocyanate is substantially below 10 percent.
摘要翻译：氯化异氰酸甲酯和/或甲基氨基甲酸氯化物在紫外线的存在下，在30〜120℃的温度范围内，通过氯化甲基氨基甲酰氯来制备N-氯羰基异氰化物二氯化物。反应过程中的温度控制在与反应混合物中甲基异氰酸酯的浓度的关系，使得在高浓度下保持低温保持高浓度，同时以低浓度保持高温。因此，当反应期间保持30〜40℃的温度时，反应混合物中甲基异氰酸酯的浓度大致超过50％; 当温度升高至65℃至75℃时，异氰酸甲酯的浓度在50％至10％的范围内; 当温度升高到75℃以上时，异氰酸甲酯的浓度显着低于10％。

20. 发明授权

US08885337B2 Retaining system for fastening an electronic auxiliary device 有权
标题翻译：用于固定电子辅助装置的固定系统
公开(公告)号：US08885337B2
公开(公告)日：2014-11-11
申请号：US13522990
申请日：2010-12-21
申请人： Jochen Schanz , Herbert Schwarz
发明人： Jochen Schanz , Herbert Schwarz
IPC分类号： G06F1/16 , B62J11/00 , B60R11/02 , B60R11/00 , B62J99/00
CPC分类号： B62J11/00 , B60R11/0258 , B60R2011/0071 , B62J2099/0033
摘要： The invention relates to a retaining system for fastening an electronic auxiliary device (13) by means of a retaining element (1), wherein in order to allow flat auxiliary devices (13) also to be reliably attached without the visibility or the operation of the auxiliary device (13) being impaired, the perimeter of the retaining element (1) effective for accommodating the auxiliary device can be adjusted larger in an open position than in a closed position by means of a cam control having a cam disk (5) and controlled by an operating lever (6). The retaining element (1) further comprises a base plate (2), wherein on the base plate (2), the operating lever (6) and the cam disk (5) engaged with the operating lever (6) are pivotably arranged and attachment elements (3) for the auxiliary device (13) that are kept under stress by at least one elastic element (4) are movably arranged, and pivoting the operating lever (6) moves the attachment elements (3) into the open position or into the closed position by means of the cam disk (5).
摘要翻译：本发明涉及一种用于通过保持元件（1）紧固电子辅助装置（13）的保持系统，其中为了允许平面辅助装置（13）也可靠地附接，而没有可见性或操作辅助装置（13）受损，通过具有凸轮盘（5）和凸轮盘（8）的凸轮控制，有效用于容纳辅助装置的保持元件（1）的周边可以在打开位置比在关闭位置更大由操作杆（6）控制。保持元件（1）还包括基板（2），其中在基板（2）上，与操作杆（6）接合的操作杆（6）和凸轮盘（5）可枢转地布置并附接通过至少一个弹性元件（4）保持在应力下的用于辅助装置（13）的元件（3）可移动地布置，并且枢转操作杆（6）使附接元件（3）移动到打开位置或者进入通过凸轮盘（5）的关闭位置。

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