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    • 15. 发明授权
    • Process for producing powdery polycarbonate from a polycarbonate solution
    • 从聚碳酸酯溶液制备粉状聚碳酸酯的方法
    • US4184911A
    • 1980-01-22
    • US913315
    • 1978-06-07
    • Hiroyuki KodaKunio HamayaHiroyuki YoshizakiYutaka KojimaShiro TsuchiyaShinichi FukudaTakashi Ikeno
    • Hiroyuki KodaKunio HamayaHiroyuki YoshizakiYutaka KojimaShiro TsuchiyaShinichi FukudaTakashi Ikeno
    • C08J3/14B01D1/24
    • C08J3/14C08J2369/00Y10S159/10
    • A process is disclosed for producing powdery polycarbonate from a polycarbonate solution which comprises:(a) charging the solution into the feed opening of a disolvating apparatus, the apparatus being composed of a casing and having at least two screws incorporated therein, the screws meshing with each other; the apparatus comprising two parts; a evaporating zone and a powdering zone; a space being provided above the screws in the evaporating zone, the space extending in the axial direction of the screws and having at least one degassing opening, and side and bottom portions of screws generally fitting with the casing in the evaporating zone; top, side and bottom portions of screws generally fitting with the casing in the powdering zone, heating means being installed in the casing and/or screws;(b) in the evaporating zone, evaporating the solvent of the polycarbonate solution using the heating means while moving the solution by the screws;(c) powdering the dried polycarbonate in the powdering zone; and(d) discharging the powdery polycarbonate from the product exit in the powdering zone.
    • 公开了一种从聚碳酸酯溶液制备粉状聚碳酸酯的方法,该方法包括:(a)将溶液装入分散装置的进料口中,该装置由壳体组成,其中并入有至少两个螺杆,螺钉与 彼此; 该装置包括两部分; 蒸发区和粉化区; 在蒸发区域的螺钉上方设置空间,该空间沿螺杆的轴向方向延伸,并且具有至少一个脱气开口,以及通常与壳体配合在蒸发区域中的螺钉的侧部和底部; 螺丝的顶部,侧面和底部通常与壳体配合在粉化区域中,加热装置安装在壳体和/或螺钉中; (b)在蒸发区内,用螺丝移动溶液时,使用加热装置蒸发聚碳酸酯溶液的溶剂; (c)将干燥的聚碳酸酯粉化在粉化区中; 和(d)从粉状区域中的产品出口排出粉末状聚碳酸酯。
    • 18. 发明授权
    • 5-fluorouracil derivatives
    • 5-氟尿嘧啶衍生物
    • US5047521A
    • 1991-09-10
    • US150407
    • 1988-02-09
    • Setsuro FujiiMitsuru HirohashiYoshihito YamamotoYutaka Kojima
    • Setsuro FujiiMitsuru HirohashiYoshihito YamamotoYutaka Kojima
    • A61K31/505A61K31/70C07D239/54C07D239/553C07D401/12C07D409/06C07D409/14C07H19/06C07H19/073H01S4/00
    • C07D239/553C07D401/12C07D409/14C07H19/06
    • This invention relates to a novel 5-fluorouracil derivative represented by the formula ##STR1## wherein R.sup.y is a hydrogen atom or a specific acyl group, Z is a phenyl-lower alkoxy-lower alkyl group, thienyl-lower alkyl group optionally substituted with halogen atom on the thienyl ring, or a group ##STR2## wherein R.sup.1 and R.sup.2 are each a hydrogen atom, a specific acyl group, phenyl-lower alkyl group having a group R.sup.x OCO-- on the phenyl ring, or a group --(A).sub.n B, R.sup.x being a specific organic group, A being a lower alkylene group, n being 0 or 1, and B being a 5- or 6-membered unsaturated heterocyclic group having 1 to 4 hetero-atoms selected from N, O and S and optionally having a benzene ring, naphthalene ring or pyridine ring condensed therewith, with the proviso that R.sup.1 and R.sup.2 are not hydrogen atoms or specific acyl groups at the same time; to a process for preparing the same; and to an anticancer composition comprising the same as an effective ingredient.
    • PCT No.PCT / JP87 / 00275 Sec。 371日期1988年2月9日 102(e)1988年2月9日PCT PCT公开1987年4月30日PCT公布。 公开号WO87 / 06582 日本公开日:1987年11月5日。本发明涉及由式(1)表示的新型5-氟尿嘧啶衍生物,其中R y为氢原子或特定酰基,Z为苯基 - 低级烷氧基 - 低级烷基 任选被噻吩基环上的卤素原子取代的噻吩基 - 低级烷基,或其中R 1和R 2各自为氢原子,特定酰基,具有基团R xOCO-的苯基 - 低级烷基基团 环,或基团 - (A)nB,Rx是特定的有机基团,A是低级亚烷基,n是0或1,B是具有1〜4个杂原子的5或6元不饱和杂环基, 选自N,O和S且任选具有苯环的原子,萘环或与其缩合的吡啶环,条件是R1和R2不同时为氢原子或特定酰基; 一个制备它的过程; 以及包含其作为有效成分的抗癌组合物。