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    • 12. 发明授权
    • Process for preparation of N-(.alpha.-alkoxyethyl)-carboxylic acid amide
    • 制备N-(α-烷氧基乙基) - 羧酸酰胺的方法
    • US4997984A
    • 1991-03-05
    • US452936
    • 1989-12-19
    • Shuichi SugitaTetsuo KudoKuniomi Marumo
    • Shuichi SugitaTetsuo KudoKuniomi Marumo
    • C07C231/12
    • C07C231/12Y02P20/582
    • A process for the preparation of an N-(.alpha.-alkoxyethyl)carboxylic acid amide represented by the following formula [I]: ##STR1## wherein R stands for a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, a benzyl group or an aryl group, and R.sup.1 stands for an alkyl group having 1 to 10 carbon atoms or a cycloalkyl group,which comprises reacting an ethylidene-bisamide represented by the following formula [II]:CH.sub.3 CH(NHCOR).sub.2 [II]wherein R stands for a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, a benzyl group or an aryl group,with an alkanol in the presence of an acid catalyst. According to this process, a high-purity N-(.alpha.-alkoxyethyl)carboxylic acid amide, which is valuable as an intermediate for the production of an N-vinylcarboxylic acid amide and the like, can be easily prepared from cheap and easily available starting materials.
    • 由下式[I]表示的制备N-(α-烷氧基乙基)羧酸酰胺的方法:其中R代表氢原子,具有1至6个碳原子的烷基, 苄基或芳基,R1表示碳原子数1〜10的烷基或环烷基,其包括使下式[II]表示的亚乙基双酰胺与CH 3 CH(NHCOR)2 [II] 其中R代表氢原子,具有1至6个碳原子的烷基,苄基或芳基,与烷基醇在酸催化剂存在下反应。 根据该方法,可以从便宜且容易获得的起始物中容易地制备作为制备N-乙烯基羧酸酰胺等的中间体有价值的高纯度N-(α-烷氧基乙基)羧酸酰胺 材料