会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 12. 发明申请
    • METHOD OF DETECTING OR QUANTITATING ENDOGENOUS WHEAT DNA AND METHOD OF DETERMINING CONTAMINATION RATE OF GENETICALLY MODIFIED WHEAT IN TEST SAMPLE
    • 检测或定量内源性DNA的方法和测定样品中遗传修饰小麦污染率的方法
    • US20120208992A1
    • 2012-08-16
    • US13366190
    • 2012-02-03
    • Shinjiro IMAIKeiko Tanaka
    • Shinjiro IMAIKeiko Tanaka
    • C07H21/04
    • C12Q1/6895
    • An object of the present invention is to discover an endogenous wheat sequence satisfying the conditions of: a) it is universally present in varieties of wheat, b) the amount present (detected amount) is not affected depending on the wheat variety, c) even if other grains are present, only wheat can be detected without cross-reactivity, and d) it is amplified quantitatively by the PCR reaction. A further object of the present invention is to provide a method of accurately detecting and quantitating endogenous wheat DNA in a test sample by the polymerase chain reaction. The present invention provides replicable DNA comprising: a DNA sequence as endogenous DNA common to both genetically modified wheat and non-genetically modified wheat; and one or more DNA sequence each comprising a sequence that is specific to a strain of genetically modified wheat.
    • 本发明的目的是发现满足以下条件的内源性小麦序列:a)其在小麦品种中普遍存在,b)存在量(检测量)不受小麦品种的影响,c)均匀 如果存在其他颗粒,则只能检测到小麦不具有交叉反应性,并且d)通过PCR反应定量扩增。 本发明的另一个目的是提供通过聚合酶链式反应准确地检测和定量测试样品中的内源性小麦DNA的方法。 本发明提供可复制的DNA,其包含:作为转基因小麦和非转基因小麦共有的内源DNA的DNA序列; 和一个或多个DNA序列,每个DNA序列各自包含对转基因小麦品系特异的序列。
    • 13. 发明授权
    • Method of detecting or quantitating endogenous wheat DNA and method of determining contamination rate of genetically modified wheat in test sample
    • 检测或定量内源性小麦DNA的方法和测定样品中转基因小麦污染率的方法
    • US08173400B2
    • 2012-05-08
    • US12300973
    • 2007-05-11
    • Shinjiro ImaiKeiko Tanaka
    • Shinjiro ImaiKeiko Tanaka
    • C12P19/34C12Q1/68
    • C12Q1/6895
    • An object of the present invention is to discover an endogenous wheat sequence satisfying the conditions of: a) it is universally present in varieties of wheat, b) the amount present (detected amount) is not affected by the wheat variety, c) even if other grains are present, only wheat can be detected without cross-reactivity, and d) it is amplified quantitatively by the PCR reaction. A further object of the present invention is to provide a method of accurately detecting and quantitating endogenous wheat DNA in a test sample by the polymerase chain reaction. The present invention provides a method of detecting or quantitating endogenous wheat DNA in a test sample by the polymerase chain reaction, the method comprising: a step of using a nucleic acid molecule in the test sample or a nucleic acid molecule extracted from the test sample as a template to amplify the nucleic acid molecule of a region consisting of the nucleotide sequence identified as SEQ ID NO: 2 or a partial sequence thereof with a primer pair capable of amplifying that region; and a step of detecting or quantitating the amplified nucleic acid molecule.
    • 本发明的目的是发现满足以下条件的内源性小麦序列:a)其在小麦品种中普遍存在,b)存在量(检测量)不受小麦品种的影响,c)即使 其他颗粒存在,只有小麦可以检测到没有交叉反应性,和d)通过PCR反应定量扩增。 本发明的另一个目的是提供通过聚合酶链式反应准确地检测和定量测试样品中的内源性小麦DNA的方法。 本发明提供了通过聚合酶链式反应检测或定量测试样品中的内源性小麦DNA的方法,所述方法包括:使用测试样品中的核酸分子或从测试样品中提取的核酸分子的步骤 用于扩增由SEQ ID NO:2所鉴定的核苷酸序列组成的区域的核酸分子或其部分序列的扩增该区域的引物对的模板; 以及检测或定量扩增的核酸分子的步骤。
    • 16. 发明申请
    • METHOD OF DETECTING OR QUANTITATING ENDOGENOUS WHEAT DNA AND METHOD OF DETERMINING CONTAMINATION RATE OF GENETICALLY MODIFIED WHEAT IN TEST SAMPLE
    • 检测或定量内源性DNA的方法和测定样品中遗传修饰小麦污染率的方法
    • US20100062432A1
    • 2010-03-11
    • US12300973
    • 2007-05-11
    • Shinjiro IMAIKeiko Tanaka
    • Shinjiro IMAIKeiko Tanaka
    • C12Q1/68C07H21/04
    • C12Q1/6895
    • An object of the present invention is to discover an endogenous wheat sequence satisfying the conditions of: a) it is universally present in varieties of wheat, b) the amount present (detected amount) is not affected depending on the wheat variety, c) even if other grains are present, only wheat can be detected without cross-reactivity, and d) it is amplified quantitatively by the PCR reaction. A further object of the present invention is to provide a method of accurately detecting and quantitating endogenous wheat DNA in a test sample by the polymerase chain reaction. The present invention provides a method of detecting or quantitating endogenous wheat DNA in a test sample by the polymerase chain reaction, the method comprising: a step of using a nucleic acid in the test sample or a nucleic acid extracted from the test sample as a template to amplify the nucleic acid of a region consisting of the base sequence identified as SEQ ID NO: 2 or a partial sequence thereof with a primer pair capable of amplifying that region; and a step of detecting or quantitating the amplified nucleic acid.
    • 本发明的目的是发现满足以下条件的内源性小麦序列:a)其在小麦品种中普遍存在,b)存在量(检测量)不受小麦品种的影响,c)均匀 如果存在其他颗粒,则只能检测到小麦不具有交叉反应性,并且d)通过PCR反应定量扩增。 本发明的另一个目的是提供通过聚合酶链式反应准确地检测和定量测试样品中的内源性小麦DNA的方法。 本发明提供了通过聚合酶链式反应检测或定量测试样品中的内源小麦DNA的方法,所述方法包括:将测试样品中的核酸或从测试样品提取的核酸作为模板的步骤 以由具有鉴定为SEQ ID NO:2的碱基序列或其部分序列组成的区域的核酸与能够扩增该区域的引物对扩增; 以及检测或定量扩增的核酸的步骤。
    • 17. 发明申请
    • Method of Detecting Relative Risk for the Onset of Atopic Dermatitis by Gene Single Nucleotide Polymorphism Analysis
    • 通过基因单核苷酸多态性分析检测特应性皮炎发病相对危险度的方法
    • US20090098107A1
    • 2009-04-16
    • US11887769
    • 2006-04-03
    • Keiko TanakaJulian M Hopkin
    • Keiko TanakaJulian M Hopkin
    • A61K39/395C12Q1/68
    • C12Q1/6883C12Q2600/156
    • The present invention provides a method of discriminating a relative risk for the morbidity of atopic dermatitis of a test subject comprising: analyzing gene polymorphism of two or more of genes related to onset of atopic dermatitis using a sample isolated from a statistically significant number of normal persons and patients of atopic dermatitis to determine relative ratios (percentages (%)) related to the individual gene polymorphism of individual derived from the analysis; and calculating an odds ratio according to specified gene polymorphism from the relative ratio; and using, as a discrimination criterion, a combination of two or more of gene polymorphisms showing a synergetically higher odds ratio than odds ratios according to individual gene polymorphism. The method is useful for predicting susceptibility of an AD patient to chemicals based on genes and for selecting the diagnostic and/or therapeutic agent by eliminating harmful drug reactions from the analysis of principal factors related to onset and development of AD and interaction among these genes, and for determining a diagnostic method and therapeutic method using the detection method of morbidity risk.
    • 本发明提供了一种鉴别测试对象特应性皮炎发病率的相对风险的方法,包括:使用从统计学上显着数量的正常人分离的样本分析与特应性皮炎发作相关的两个或更多个基因的基因多态性 和特应性皮炎患者确定与分析得出的个体个体基因多态性相关的相对比例(百分比(%)); 并根据相对比例根据规定的基因多态性计算优势比; 并且根据个体基因多态性,使用两种或更多种基因多态性的组合,其显示出比优势比的协同优势比值比。 该方法可用于预测基于基因的AD患者对化学物质的敏感性,并且通过从与AD发生和发展以及这些基因之间的相互作用相关的主要因素的分析中消除有害药物反应来选择诊断和/或治疗剂, 并用于确定使用发病风险检测方法的诊断方法和治疗方法。