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11. 发明授权

US5234934A Aminopropanol derivatives, process for their preparation and pharmaceutical compositions comprising the same 失效
标题翻译：氨基丙醇衍生物，其制备方法和包含其的药物组合物
公开(公告)号：US5234934A
公开(公告)日：1993-08-10
申请号：US876091
申请日：1992-04-30
申请人： Zoltan Budai , Klara Reiter nee Esses , Eniko Sziri nee Kiszelly , Gizella Zsila , Gabor Gigler , Lujza Petocz , Maria Szecsey nee Hegedus , Marton Fekete , Valeria Hoffmann , Laszlo Kapolnai
发明人： Zoltan Budai , Klara Reiter nee Esses , Eniko Sziri nee Kiszelly , Gizella Zsila , Gabor Gigler , Lujza Petocz , Maria Szecsey nee Hegedus , Marton Fekete , Valeria Hoffmann , Laszlo Kapolnai
IPC分类号： C07C251/58 , C07D213/16 , C07D295/088
CPC分类号： C07D213/16 , C07C251/58 , C07D295/088 , C07C2101/02 , C07C2101/08 , C07C2101/14 , C07C2101/18
摘要： The invention relates to novel racemic or optically active aminopropanol derivatives of formula I ##STR1## wherein R and R.sup.1 are independently hydrogen atom, halogen atom, lower alkoxy, or together represent a methylene dioxy group,R.sup.2 and R.sup.3 together represent a chemical bond or independently stand for a hydrogen atom,R.sup.4 and R.sup.5 are independently hydrogen atom, C.sub.3-7 cycloalkyl group or straight or branched, saturated or unsaturated C.sub.1-12 alkyl group optionally substituted by one or more dialkyl-aminoalkyl, dimethoxyphenyl or phenyl groups, orR.sup.4 and R.sup.5 together with the adjacent nitrogen atom form a 4 to 7 membered ring optionally comprising an oxygen, sulfur or a further nitrogen atom, which ring is optionally substituted by a phenyl, benzyl or C.sub.1-3 alkyl group and the said substituents may carry a hydroxyl group, one or two methoxy groups, halogen atoms or trifluoromethyl groups, orR.sup.4 and R.sup.5 together with the adjacent nitrogen atom form a piperidine ring which is optionally substituted by a phenyl or benzyl group and, if desired, it comprises a double bond,R.sup.6 stands for hydrogen atom or benzoyl group, andn represents an integer from 3 to 6,acid-addition salts and quaternary ammonium derivatives thereof.Further the invention relates to processes for preparing these compounds.The compounds of the invention exert cardiac circulation controlling and/or improving, central nervous system tranquillizing and/or digestive system irregulations improving effects.
摘要翻译：本发明涉及式I的新型外消旋或光学活性氨基丙醇衍生物其中R和R 1独立地为氢原子，卤素原子，低级烷氧基或一起代表亚甲基二氧基，R2和R3一起表示化学键或独立地代表氢原子，R4和R5独立地是氢原子，C3-7环烷基或任选被一个或多个二烷基氨基烷基，二甲氧基苯基或苯基取代的直链或支链，饱和或不饱和的C 1-12烷基，或R 4 和R5与相邻的氮原子一起形成任选地包含氧，硫或另外的氮原子的4至7元环，该环任选被苯基，苄基或C 1-3烷基取代，所述取代基可以携带羟基，一个或两个甲氧基，卤素原子或三氟甲基，或R4和R5与相邻的氮原子一起形成哌啶环，其任选地是由苯基或苄基构成，如果需要，它包含双键，R6代表氢原子或苯甲酰基，n代表3-6的整数，其酸加成盐和季铵衍生物。本发明还涉及制备这些化合物的方法。本发明的化合物发挥心脏循环控制和/或改善，中枢神经系统镇定和/或消化系统不调节改善作用。

12. 发明授权

US4621101A Pharmaceutical compositions with antianginal activity 失效
标题翻译：具有抗心绞痛活性的药物组合物
公开(公告)号：US4621101A
公开(公告)日：1986-11-04
申请号：US751623
申请日：1985-07-02
申请人： Zoltan Budai , Tibor Mezei , Aranka Lay nee Konya , Lujza Petocz , Katalin Grasser , Zsuzsanna Orr
发明人： Zoltan Budai , Tibor Mezei , Aranka Lay nee Konya , Lujza Petocz , Katalin Grasser , Zsuzsanna Orr
IPC分类号： A61K31/15 , A61P43/00 , C07C251/38
CPC分类号： C07C251/58 , C07C2101/14 , C07C2101/18
摘要： The invention relates to pharmaceutical compositions possessing valuable antianginal activity. These compositions show higher activity and more favorable therapeutic indices than the reference compound Prenylamine. Preparation of different kinds of pharmaceutical compositions, such as tablets, dragees, capsules and injectable solutions, containing compounds of general formula (I) ##STR1## or their acid addition salts as active ingredients, is disclosed, wherein in formula (I)R is phenyl or 4-chlorophenyl;R.sup.1 and R.sup.2 each represent hydrogen, methyl or isopropyl;R.sup.3 and R.sup.4 are hydrogen, or together form a chemical bond;n is an integer from 4 to 6;A means trimethylene, if n is 4 or 6; or ethylene, if n is 5.
摘要翻译：本发明涉及具有有价值的抗心绞痛活性的药物组合物。这些组合物显示比参考化合物Prenylamine更高的活性和更有利的治疗指数。公开了含有通式（I）化合物或其酸加成盐作为活性成分的不同种类的药物组合物如片剂，硫化物，胶囊和可注射溶液的制备，其中在式（I）中R是苯基或4-氯苯基; R1和R2各自表示氢，甲基或异丙基; R3和R4是氢，或一起形成化学键; n为4-6的整数; 如果n为4或6，则表示三亚甲基; 或乙烯，如果n为5。

13. 发明授权

US4425158A Bicyclo(2.2.1)heptane oximes used for plant growth regulating 失效
标题翻译：用于植物生长调节的双环（2.2.1）庚烷肟
公开(公告)号：US4425158A
公开(公告)日：1984-01-10
申请号：US322675
申请日：1981-11-18
申请人： Zoltan Budai , Attila Kis-Tamas , Tibor Mezei , Aranka Lay nee Konya , Zoltan Vigh , Agnes Sokorai nee Janki
发明人： Zoltan Budai , Attila Kis-Tamas , Tibor Mezei , Aranka Lay nee Konya , Zoltan Vigh , Agnes Sokorai nee Janki
IPC分类号： A01N33/24 , A01N33/04 , A01N35/10 , A01P21/00 , C07C251/44 , C07C251/50
CPC分类号： A01N35/10
摘要： The invention relates to new bicyclo(2.2.1)heptane derivatives of the general formula I ##STR1## wherein R represents a C.sub.1-12 alkyl group optionally substituted by a lower alkoxy group, a C.sub.2-4 alkenyl group or a phenyl-(lower alkyl) group optionally substituted on the phenyl ring by one or more lower alkoxy groups or halogen atoms.The invention relates further to plant growth regulating compositions comprising as active agent 0.001 to 95% by weight of a racemic and/or optically active compound of the general formula I, wherein R has the above defined meanings, along with a conventional organic or inorganic, solid and/or liquid carrier and/or filler and/or diluent and/or surfactant.The invention encompasses also the preparation of the compounds of the general formula I which comprises reacting a racemic or optically active compound of the general formula II ##STR2## wherein Y is an oxygen or sulfur atom or an oxim group, with a compund of the general formula IIIR - XwhereinR is as defined above, andX represents a leaving group, preferably a halogen atom, a sulfonyloxy or an aminooxy group, with the proviso that when using a compound of the general formula II, in which Y is an oxim group, X is other than aminooxy group,in the presence of a basic condensing agent, and optionally resolving the racemic compound of the general formula I obtained into its optically active antipodes.
摘要翻译：本发明涉及通式I的新的双环（2.2.1）庚烷衍生物，其中R表示任选被低级烷氧基，C 2-4链烯基或苯基 - （低级烷基）基团，其任选在苯环上被一个或多个低级烷氧基或卤素原子取代。本发明进一步涉及植物生长调节组合物，其包含作为活性剂0.001至95重量％的通式I的外消旋和/或旋光活性化合物，其中R具有上述定义的含义，以及常规的有机或无机，固体和/或液体载体和/或填料和/或稀释剂和/或表面活性剂。本发明还包括通式I的化合物的制备，其包括使通式II的外消旋或旋光活性化合物其中Y是氧或硫原子或肟基，与下列化合物反应：通式III R-X其中R如上定义，X表示离去基团，优选卤素原子，磺酰氧基或氨基氧基，条件是当使用通式II的化合物时，其中Y为肟基，X不是氨基氧基，在碱性缩合剂的存在下，并且任选地将所得通式I的外消旋化合物拆分成其光学活性对映体。

14. 发明授权

US4077999A Novel oxime ethers 失效
标题翻译：新型肟醚
公开(公告)号：US4077999A
公开(公告)日：1978-03-07
申请号：US749399
申请日：1976-12-10
申请人： Zoltan Budai , Aranka Lay nee Konya , Tibor Mezei , Katalin Grasser , Eniko Szirt nee Kiszelly , Ibolya Kosoczky , Lujza E. Petocz
发明人： Zoltan Budai , Aranka Lay nee Konya , Tibor Mezei , Katalin Grasser , Eniko Szirt nee Kiszelly , Ibolya Kosoczky , Lujza E. Petocz
IPC分类号： C07C251/58 , C07D295/088 , C07C131/02 , C07C131/04
CPC分类号： C07D295/088 , C07C251/58 , C07C2101/08 , C07C2101/16 , C07C2101/18
摘要： The invention relates to novel oxime ethers of the formula I ##STR1## wherein R stands for a phenyl group which may be substituted by a halogen atom or by one or more C.sub.1 -C.sub.4 alkoxy, hydroxyl, nitro or di(C.sub.1 -C.sub.3 alkyl)amino groups,R.sup.1 and R.sup.2 denote each a hydrogen atom or together a valence bond,A denotes a C.sub.2 -C.sub.4 straight or branched-chain alkylene group,N denotes an integer from 3 to 10, andR.sup.3 and R.sup.4 denote a hydrogen atom or a C.sub.1 -C.sub.4 alkyl group, furthermore to acid addition salts and quaternary ammonium salts thereof. These new compounds are biologically active, and possess primarily local analgesic, spasmolytic, nicotine-lethality inhibiting, tetrabenazine-antagonistic and tetra-cor-spasm inhibiting effects.
摘要翻译：本发明涉及式I（I）的新型肟醚，其中R代表可被卤素原子取代的苯基或一个或多个C 1 -C 4烷氧基，羟基，硝基或二（C1- C 3烷基）氨基，R 1和R 2各自表示氢原子或价键一起，A表示C 2 -C 4直链或支链亚烷基，N DENOTES AN INTEGER为3〜10，R 3和R 4表示氢原子或C1-C4烷基，此外还涉及其酸加成盐和季铵盐。这些新化合物具有生物活性，主要具有局部镇痛，解痉，尼古丁致死抑制，四苯并嗪拮抗和四痉挛抑制作用。

15. 发明授权

US4588435A N-substituted amino propane sulfonic acid derivatives and plant growth regulating use 失效
标题翻译： N-取代氨基丙磺酸衍生物和植物生长调节用途
公开(公告)号：US4588435A
公开(公告)日：1986-05-13
申请号：US696658
申请日：1985-01-31
申请人： Zoltan Budai , Attila Kis-Tamas , Aranka Lay nee Konya , Zoltan Vig , Viktor Andriska , Tibor Mezei
发明人： Zoltan Budai , Attila Kis-Tamas , Aranka Lay nee Konya , Zoltan Vig , Viktor Andriska , Tibor Mezei
IPC分类号： A01N37/18 , A01N41/04 , A01N43/08 , A01P21/00 , C07C67/00 , C07C301/00 , C07C303/22 , C07C303/32 , C07C309/15 , C07D307/68 , A01N37/22 , C07C143/63
CPC分类号： A01N41/04 , A01N43/08
摘要： The invention relates to new N-substituted amino propane sulfonic acid derivatives of the Formula I ##STR1## and salts and hydrates thereof, a process for the preparation thereof and plant growth regulating agents comprising the same whereinR.sup.1 and R.sup.2 may be identical or different and stand for hydrogen, halogen, lower alkyl or lower alkoxy andR stands for furyl; or lower alkyl or phenyl the two latter groups being optionally substituted by one or more halogeno atom(s).
摘要翻译：本发明涉及式I的新的N-取代氨基丙磺酸衍生物及其盐及其水合物，其制备方法和包含其的植物生长调节剂，其中R1和R2可以相同或不同代表氢，卤素，低级烷基或低级烷氧基，R代表呋喃基; 或低级烷基或苯基，后两个基团任选被一个或多个卤素原子取代。

16. 发明授权

US4511737A Bicyclo(2.2.1)heptane oximes 失效
标题翻译：双环（2.2.1）庚烷肟
公开(公告)号：US4511737A
公开(公告)日：1985-04-16
申请号：US551941
申请日：1983-11-15
申请人： Zoltan Budai , Attila Kis-Tamas , Tibor Mezei , Aranka Lay , Zoltan Vigh , Agnes Sokorai
发明人： Zoltan Budai , Attila Kis-Tamas , Tibor Mezei , Aranka Lay , Zoltan Vigh , Agnes Sokorai
IPC分类号： A01N33/24 , A01N33/04 , A01N35/10 , A01P21/00 , C07C251/44 , C07C251/50 , C07C131/02
CPC分类号： A01N35/10
摘要： The invention relates to new bicyclo(2.2.1)heptane derivatives of the general formula I ##STR1## wherein R represents a C.sub.1-12 alkyl group optionally substituted by a lower alkoxy group, a C.sub.2-4 alkenyl group or a phenyl-(lower alkyl) group optionally substituted on (I), phenyl ring by one or more lower alkoxy groups or halogen atoms.The invention relates further to plant growth regulating compositions comprising as active agent 0.001 to 95% by weight of a racemic and/or optically active compound of the general formula I, wherein R has the above defined meanings, along with a conventional organic or inorganic, solid and/or liquid carrier and/or filler and/or diluent and/or surfactant.The invention encompasses also the preparation of the compounds of the general formula (I) which comprises reacting a racemic or optically active compound of the general formula (II) ##STR2## wherein Y is an oxygen or sulfur atom or an oxim group, with a compound of the general formula (III)R--XwhereinR is as defined above, andX represents a leaving group, preferably a halogen atom, a sulfonyloxy or an aminooxy group, with the proviso that when using a compound of the general formula (II), in which Y is an oxim group, X is other than aminooxy group,in the presence of a basic condensing agent, and optionally resolving the racemic compound of the general formula (I) obtained into its optically active antipodes.
摘要翻译：本发明涉及通式I（I）的新型双环（2.2.1）庚烷衍生物，其中R表示任选被低级烷氧基取代的C 1-12烷基，C 2-4链烯基或苯基 - （低级烷基）基团，其任选地在（I）上取代，苯基环由一个或多个低级烷氧基或卤素原子取代。本发明进一步涉及植物生长调节组合物，其包含作为活性剂0.001至95重量％的通式I的外消旋和/或旋光活性化合物，其中R具有上述定义的含义，以及常规的有机或无机，固体和/或液体载体和/或填料和/或稀释剂和/或表面活性剂。本发明还包括通式（I）的化合物的制备，其包括使通式（II）的外消旋或光学活性化合物其中Y是氧或硫原子或肟基的（II）与通式（III）RX的化合物，其中R如上定义，X表示离去基团，优选卤素原子，磺酰氧基或氨基氧基，条件是当使用通式（II），其中Y是肟基，X不是氨基氧基，在碱性缩合剂的存在下，并且任选地将通式（I）的外消旋化合物拆分成其光学活性对映体。

17. 发明授权

US5254547A Thioacid amide derivatives and fodder compositions containing the same 失效
标题翻译：含硫酰胺衍生物和含有它们的饲料组合物
公开(公告)号：US5254547A
公开(公告)日：1993-10-19
申请号：US802236
申请日：1991-12-04
申请人： Zoltan Budai , Tibor Mezei , Klara Reiter nee Esses , Lajos Fekete , Karoly Magyar , Attila Nagy , Laszlo Puskas
发明人： Zoltan Budai , Tibor Mezei , Klara Reiter nee Esses , Lajos Fekete , Karoly Magyar , Attila Nagy , Laszlo Puskas
IPC分类号： A23K1/16 , C07D295/18 , C07D295/194 , A61K31/535
CPC分类号： C07D295/194 , Y10S426/807
摘要： The invention relates to new thioacid amide derivatives, a process for the preparation thereof, compositions, particularly feed additives, premixes and ready-for-use fodders, comprising the same, further to a method for increasing weight gain and improving fodder utilization of domestic animals.The new thioacid amide derivatives of the general formula (I), whereinR represents hydrogen, C.sub.1-18 alkyl, C.sub.2-6 alkenyl or C.sub.2-6 alkynyl andR.sup.1 stands for hydrogen, halogen or methoxy, with the provisos thata) at least one of R and R.sup.1 is other than hydrogen;b) if R represents ethyl, R.sup.1 is other than hydrogen; andc) if R stands for methyl, R.sup.1 is other than hydrogen or methoxy,exhibit useful weight-gain increasing and fodder-utilization improving effects and can be used in animal husbandry, particularly in pig.

18. 发明授权

US4395413A Oxime ethers and pharmaceutical compositions containing the same 失效
标题翻译：肟醚和含有它的药物组合物
公开(公告)号：US4395413A
公开(公告)日：1983-07-26
申请号：US162674
申请日：1980-06-24
申请人： Zoltan Budai , Aranka Lay nee Konya , Tibor Mezei , Lujza Petocz , Katalin Grasser , Ibolya Kosoczky , Eniko Szirt nee Kiszelly , Peter Gorog
发明人： Zoltan Budai , Aranka Lay nee Konya , Tibor Mezei , Lujza Petocz , Katalin Grasser , Ibolya Kosoczky , Eniko Szirt nee Kiszelly , Peter Gorog
IPC分类号： A61K31/15 , A61K31/495 , A61P25/04 , C07C67/00 , C07C239/00 , C07C249/10 , C07C251/58 , C07D295/02 , C07D295/088 , C07D295/08
CPC分类号： C07D295/088 , Y10S514/926 , Y10S514/927
摘要： The invention relates to novel oxime ethers of the general formula /I/ and acid addition salts and quaternary ammonium derivatives thereof, ##STR1## wherein A represents a C.sub.2-6 straight or branched alkylene chain,R and R.sup.1 each represent a C.sub.1-6 alkyl group or they form together with the adjacent nitrogen atom a heterocyclic ring containing 4 to 7 carbon atoms and optionally a further hetero atom, i.e. an oxygen, sulfur or nitrogen atom, and said ring may be optionally substituted by a C.sub.1-3 alkyl, phenyl or benzyl group,R.sup.2 and R.sup.3 each denote a hydrogen atom or together form a valency bond,R.sup.4 denotes a C.sub.1-10 alkyl or C.sub.2-10 alkenyl group, andn denotes an integer from 3 to 7.The compounds of the general formula /I/ are prepared according to the invention by reacting a cycloalkane derivative of the general formula /II/ ##STR2## wherein R.sup.2, R.sup.3, R.sup.4 and n have the same meaning as above, whereasY denotes an oxygen or sulphur atom or a .dbd.N--OH group with an aminoalkyl derivative of the general formula /III/ ##STR3## wherein R, R.sup.1 and A have the same meaning as stated above andZ means a halogen atom or a H.sub.2 N--O-- group or a salt thereof in the presence of a basic condensing agent.The new compounds of the general formula /I/ possess valuable nicotine-lethality inhibiting, local anaesthetic, analgesic effects, which are, in case of certain compounds, complemented by anti-hypertensive, maximum electroshock and tetracorspasm inhibiting, ulcus inhibiting and motility inhibiting effects, and can be applied to advantage in the therapy.
摘要翻译：本发明涉及通式I I的新型肟醚及其酸加成盐和季铵衍生物，其中A表示C2-6直链或支链亚烷基链，R和R1各自表示C1 -6烷基，或者它们与相邻的氮原子一起与含有4至7个碳原子的杂环和任选的另外的杂原子（即氧，硫或氮原子）一起形成，并且所述环可以任选地被C 1-3 烷基，苯基或苄基，R2和R3各自表示氢原子或一起形成价键，R4表示C1-10烷基或C2-10烯基，n表示3至7的整数。根据本发明通过使通式/ II / IMAGE / II /的环烷烃衍生物与其中R2，R3，R4和n具有与上述相同的含义反应制备通式/ I / I，而Y表示氧或硫原子或a =具有氨基烷基衍生物的N-OH基团通式/ III / / III /其中R，R 1和A具有与上述相同的含义，Z表示在碱性缩合剂存在下的卤素原子或H 2 N-O-基或其盐。新型化合物/ I /具有有价值的尼古丁杀伤力抑制，局部麻醉，止痛作用，在某些化合物的情况下，补充有抗高血压，最大电休克和四疣抑制作用，抑制溃疡和运动抑制作用，并且可以在治疗中有利地应用。

19. 发明授权

US4310348A Plant growth regulating compositions 失效
标题翻译：植物生长调节成分
公开(公告)号：US4310348A
公开(公告)日：1982-01-12
申请号：US166975
申请日：1980-07-09
申请人： Zoltan Budai , Ferenc Jurak , Attila Kis-tamas , Aranka Lay nee Konya , Tibor Mezei , Zoltan Vig , Terez Zubovits nee Kristof
发明人： Zoltan Budai , Ferenc Jurak , Attila Kis-tamas , Aranka Lay nee Konya , Tibor Mezei , Zoltan Vig , Terez Zubovits nee Kristof
IPC分类号： A01N33/24 , A01N35/10 , C07C249/04 , C07C251/44 , A01N33/02
CPC分类号： A01N35/10
摘要： Racemic or optionally active 2-(propargyloxyimino)-1,7,7-trimethyl-bicyclo[2,2,1]heptane of the formula (I) ##STR1## or a mixture of these isomers is prepared by reacting a racemic or optically active 1,7,7-trimethyl-bicyclo[2,2,1]heptane derivative of the general formula (II), ##STR2## wherein Y stands for oxygen atom, sulfur atom or oxime group, with a propyne derivative of the general formula (III),R--CH.sub.2 --C.tbd.CH (III)whereinR stands for halogen atom or aminooxy group, with the proviso that if Y represents oxime group, R may stand only for halogen, and if R represents aminooxy group, Y may stand only for oxygen or sulfur atom.The resulting product is new and possesses strong plant growth promoting and insecticidal effects.This is a division of application Ser. No. 065,156, filed Aug. 9, 1979, now U.S. Pat. No. 4,244,888, Jan. 13, 1981.
摘要翻译：式（I）的外消旋或任选活性的2-（炔丙氧基亚氨基）-1,7,7-三甲基 - 双环[2,2,1]庚烷或其混合物或这些异构体的混合物通过使外消旋或光学活性的通式（II）的17,7-三甲基 - 双环[2,2,1]庚烷衍生物，其中Y代表氧原子，硫原子或肟基，其中通式（III）的丙炔衍生物，其中R代表卤素原子或氨基氧基的R-CH 2 -C 3 CHCH（III），条件是如果Y表示肟基，则R可以仅为卤素，如果 R表示氨基氧基，Y可以仅为氧或硫原子。

20. 发明授权

US4244888A Plant growth regulating and insecticidal compositions 失效
标题翻译：植物生长调节和杀虫组合物
公开(公告)号：US4244888A
公开(公告)日：1981-01-13
申请号：US65156
申请日：1979-08-09
申请人： Zoltan Budai , Ferenc Jurak , Attila Kis-Tamas , Aranka Lay nee Konya , Tibor Mezei , Zoltan Vig , Terez Zubovits nee Kristof
发明人： Zoltan Budai , Ferenc Jurak , Attila Kis-Tamas , Aranka Lay nee Konya , Tibor Mezei , Zoltan Vig , Terez Zubovits nee Kristof
IPC分类号： A01N33/24 , A01N35/10 , C07C249/04 , C07C251/44 , C07C131/02
CPC分类号： A01N35/10
摘要： Racemic or optically active 2-(propargyloxyimino)-1,7,7-trimethyl-bicyclo[2,2,1]heptane of the formula (I) ##STR1## or a mixture of these isomers is prepared by reacting a racemic or optically active 1,7,7-trimethyl-bicyclo[2,2,1]heptane derivative of the general formula (II), ##STR2## wherein Y stands for oxygen atom, sulfur atom or oxime group, with a propyne derivative of the general formula (III),R--CH.sub.2 --C.tbd.CH (III) whereinR stands for halogen atom or aminooxy group, with the proviso that if Y represents oxime group, R may stand only for halogen, and if R represents aminooxy group, Y may stand only for oxygen or sulfur atom.The resulting product is new and possesses strong plant growth promoting and insecticidal effects.
摘要翻译：式（I）的外消旋或光学活性的2-（炔丙氧基亚氨基）-1,7,7-三甲基 - 双环[2,2,1]庚烷或其混合物可以通过使外消旋或光学活性的通式（II）的17,7-三甲基 - 双环[2,2,1]庚烷衍生物，其中Y代表氧原子，硫原子或肟基，其中通式（III）的丙炔衍生物，其中R代表卤素原子或氨基氧基的R-CH 2 -C 3 CHCH（III），条件是如果Y表示肟基，则R可以仅为卤素，如果 R表示氨基氧基，Y可以仅为氧或硫原子。产生的产品是新的，具有很强的植物生长促进和杀虫作用。

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