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    • 12. 发明申请
    • Skin Retention Device for a Medical Jet Injection Kit
    • 用于医用喷射注射套件的皮肤保持装置
    • US20110270217A1
    • 2011-11-03
    • US13181126
    • 2011-07-12
    • TORBEN STROEM HANSENJens Ulrik Poulsen
    • TORBEN STROEM HANSENJens Ulrik Poulsen
    • A61M5/30
    • A61M5/30A61M5/42A61M2005/3104G06F19/00
    • A skin retention device 10 for a medical jet-injection unit 20 comprises a contact face provided with adhesive 12 in the area surrounding and close to the injection opening(s) 11 of the nozzle 21 which ensures god contact between the nozzle 21 and the skin 30 of a subject in the area chosen for an injection. Consequently the injection force can be lowered dramatically. In case of two-stage jet-injections, the initial injection force can be lowered because the skin retention close to the injection point significantly reduces the energy consuming elastic expansion of the skin 30 in the injection area, and the second injection force can be lowered because of the high degree of fixed positioning of the injection opening of the nozzle 21 relative to the injection channel in the skin 30 made during the initial injection stage. Thus a high degree of injection safety is achieved, minimizing the risk of whet shots, while skin lift and lower injection force decreases the risk of damage of the underlying tissue.
    • 用于医疗喷射单元20的皮肤保持装置10包括在围绕和靠近喷嘴21的喷射开口11的区域中设置有粘合剂12的接触面,其确保喷嘴21和皮肤之间的神接触 选择注射区域的受试者30例。 因此,喷射力可以显着降低。 在两级喷射注射的情况下,初始注射力可以降低,因为靠近注射点的皮肤保留显着降低了注射区域中皮肤30的能量消耗弹性膨胀,并且可以降低第二注射力 因为喷嘴21的喷射开口相对于在初始喷射阶段期间形成的皮肤30中的喷射通道的高度固定定位。 因此,实现了高程度的注射安全性,尽可能减少磨损的风险,而皮肤提升和较低的注射力降低了潜在组织损伤的风险。
    • 15. 发明授权
    • Dose setting device
    • 剂量设定装置
    • US06340357B1
    • 2002-01-22
    • US09360263
    • 1999-07-26
    • Jens Ulrik PoulsenHenrik LjunggreenLars Hofmann Christensen
    • Jens Ulrik PoulsenHenrik LjunggreenLars Hofmann Christensen
    • A61M500
    • A61M5/20A61M5/14546A61M5/14566A61M5/31525A61M5/31546A61M2005/31588A61M2205/581G06F19/00Y10S128/01
    • The present invention relates to a drug delivery device wherein a dose to be apportioned from a cartridge is set by changing the relative position of co-operating dose setting elements (3, 5) and is injected by pressing a button (5) until this button abuts a stop (6). By operation of count up (7) or count down (8) buttons the dose is set and read into an electronic circuit (9) comprising a microprocessor and the dose setting movement of the dose setting elements relative to each other is performed by a motor (11) controlled by the circuit in accordance with the read in dose. The set dose is shown on a display (10). The motor (11) is further controlled to perform certain movements of the piston rod (3) so as retraction of this rod when a cartridge (1) is going to be changed an advancing of the piston rod to abutment with the piston (2) after the cartridge has been changed and further to advance this piston to expel air from the cartridge.
    • 本发明涉及一种药物输送装置,其中通过改变配合剂量设定元件(3,5)的相对位置来设定从药筒分配的剂量,并且通过按压按钮(5)注射直到该按钮 停靠(6)。 通过计数(7)或倒计时(8)按钮的操作,剂量被设置并读入包括微处理器的电子电路(9),并且剂量设定元件相对于彼此的剂量设定运动由电动机 (11)由电路按照读取的剂量控制。 设定的剂量显示在显示器(10)上。 电动机(11)被进一步控制以执行活塞杆(3)的某些运动,以便当筒(1)将改变活塞杆的前进以与活塞(2)邻接时,该杆的缩回, 在盒被改变之后,并且进一步推进该活塞以从盒中排出空气。
    • 16. 发明授权
    • Seal for a prefilled medical jet injection device
    • 预填充医用喷射装置的密封
    • US08920365B2
    • 2014-12-30
    • US12162614
    • 2007-01-19
    • Jens Ulrik Poulsen
    • Jens Ulrik Poulsen
    • A61M5/30A61M5/31A61M5/315
    • A61M5/30A61M2005/3103A61M2005/3106A61M2005/3118A61M2005/312A61M2005/31516
    • A sealing membrane 20 on a nozzle 10 for a jet injection device is adapted to seal off the nozzle orifice 12 by having a sealing rim 22 surrounding the nozzle orifice 12, which ensures a distinct closure of the nozzle orifice 12 to protect the nozzle geometry against damage and dirt and to protect the drug 30 contained in the cartridge 10 against contamination. The sealing rim 22 can narrowly enclose the nozzle orifice 12, or in case an adhesive 14 is applied to the nozzle face to ensure skin retention during injection, the sealing rim 22 can run in the middle of the adhesive covered area or entirely outside the adhesive covered area to protect the adhesive as well. A third sealing member 23 can also be provided to give a third distinct closure assurance in case the primary and secondary sealing membrane 20 is damaged. The third sealing member 23 can be one or more plug(s) adapted to press fit inside the nozzle orifice.
    • 用于喷射装置的喷嘴10上的密封膜20适于通过具有围绕喷嘴孔12的密封边缘22来密封喷嘴孔12,该密封边缘22确保喷嘴孔12的明显封闭以保护喷嘴几何形状抵抗 损坏和污垢并且保护容纳在盒10中的药物30免受污染。 密封边缘22可以狭窄地包围喷嘴孔12,或者在将粘合剂14施加到喷嘴面以确保注射期间的皮肤保持的情况下,密封边缘22可以在粘合剂覆盖区域的中间或完全在粘合剂的外侧延伸 覆盖区域也保护粘合剂。 也可以提供第三密封构件23,以在初级和次级密封膜20损坏的情况下提供第三种不同的封闭保证。 第三密封构件23可以是适于压配合在喷嘴孔内的一个或多个塞子。
    • 17. 发明申请
    • Seal for a Prefilled Medical Jet Injection Device
    • 预灌注医疗喷射装置的密封
    • US20090099510A1
    • 2009-04-16
    • US12162614
    • 2007-01-19
    • Jens Ulrik Poulsen
    • Jens Ulrik Poulsen
    • A61M5/307
    • A61M5/30A61M2005/3103A61M2005/3106A61M2005/3118A61M2005/312A61M2005/31516
    • A sealing membrane 20 on a nozzle 10 for a jet injection device is adapted to seal off the nozzle orifice 12 by having a sealing rim 22 surrounding the nozzle orifice 12, which ensures a distinct closure of the nozzle orifice 12 to protect the nozzle geometry against damage and dirt and to protect the drug 30 contained in the cartridge 10 against contamination. The sealing rim 22 can narrowly enclose the nozzle orifice 12, or in case an adhesive 14 is applied to the nozzle face to ensure skin retention during injection, the sealing rim 22 can run in the middle of the adhesive covered area or entirely outside the adhesive covered area to protect the adhesive as well. A third sealing member 23 can also be provided to give a third distinct closure assurance in case the primary and secondary sealing membrane 20 is damaged. The third sealing member 23 can be one or more plug(s) adapted to press fit inside the nozzle orifice.
    • 用于喷射装置的喷嘴10上的密封膜20适于通过具有围绕喷嘴孔12的密封边缘22来密封喷嘴孔12,该密封边缘22确保喷嘴孔12的明显封闭以保护喷嘴几何形状抵抗 损坏和污垢并且保护容纳在盒10中的药物30免受污染。 密封边缘22可以狭窄地包围喷嘴孔12,或者在将粘合剂14施加到喷嘴面以确保注射期间的皮肤保持的情况下,密封边缘22可以在粘合剂覆盖区域的中间或完全在粘合剂的外侧延伸 覆盖区域也保护粘合剂。 也可以提供第三密封构件23,以在初级和次级密封膜20损坏的情况下提供第三种不同的封闭保证。 第三密封构件23可以是适于压配合在喷嘴孔内的一个或多个塞子。
    • 20. 发明授权
    • Medical device
    • 医疗装置
    • US06582408B1
    • 2003-06-24
    • US09349748
    • 1999-07-08
    • Thomas Buch-RasmussenBenny MunkJens Ulrik PoulsenHenrik LjungreenPeter Møller JensenJens Møller Jensen
    • Thomas Buch-RasmussenBenny MunkJens Ulrik PoulsenHenrik LjungreenPeter Møller JensenJens Møller Jensen
    • A61M500
    • A61M5/315A61M5/24A61M5/3129A61M5/31525A61M5/31535A61M5/31566A61M5/31578A61M2005/2407A61M2005/2488A61M2005/2492
    • The present invention relates to a medication delivery device comprising a cartridge assembly, a dosing assembly and optionally a needle assembly. The cartridge assembly comprises a cartridge having a stopper adapted to receive a plunger. Furthermore, the cartridge assembly has one end sealed with a pierce able sealing, said end comprising coupling device for engaging a needle assembly, and another end comprising coupling device for engaging the dosing assembly. The dosing assembly comprises a plunger and has coupling device for engaging the cartridge assembly. The cartridge assembly and the dosing assembly are coupled together for delivering selected doses of medication. The device further comprises mechanism for securing that the plunger abuts on the stopper during use of the device, in particular when the dosing assembly is releasable coupled to the cartridge assembly. The securing mechanism is preferably a mechanism for preventing the cartridge assembly from being inadvertently released from the dosing assembly. The cartridge is preferably molded from a plastic material, such as a transparent material, and may be housed in a cartridge housing for protection of the cartridge. The medication delivery device is especially suitable for delivering insulin, growth hormone or the like medicines.
    • 本发明涉及药物输送装置,其包括药筒组件,剂量组合件和任选的针组件。 盒组件包括具有适于容纳柱塞的止动件的盒。 此外,盒组件具有用可刺穿密封件密封的一端,所述端部包括用于接合针组件的联接装置,以及包括用于接合给药组件的联接装置的另一端。 配料组件包括柱塞并具有用于接合盒组件的联接装置。 药筒组件和剂量组合件联接在一起以递送选定剂量的药物。 该装置还包括用于在使用装置期间固定柱塞抵靠止动件的机构,特别是当定量给料组件可释放地联接到药筒组件时。 固定机构优选地是用于防止盒组件被无意地从定量给料组件释放的机构。 盒优选地由诸如透明材料的塑料材料模制,并且可以容纳在盒壳体中以保护盒。 药物输送装置特别适用于输送胰岛素,生长激素等药物。