专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明授权

US06227896B1 Terminal connection mechanism used for a backlit display 失效
标题翻译：终端连接机构用于背光显示
公开(公告)号：US06227896B1
公开(公告)日：2001-05-08
申请号：US09568417
申请日：2000-05-10
申请人： George Chang
发明人： George Chang
IPC分类号： H01R13625
CPC分类号： H01R13/6272
摘要： A terminal connection mechanism used in an electroluminescent display structure primarily comprises a display panel housed in a decorative case and a terminal portion provided on the lower end of the display panel to receive a connector affixed by electrical conductive wires. The connector is provided on one side wall face thereof with a resilient locating plate that enables the connector to be detachably secured in position in the case. Thus the terminal connection mechanism according to the invention can provide an electroluminescent display the convenience in connection and separation between a display panel and its electrical conductive wires. It has practical value in industry.
摘要翻译：用于电致发光显示结构的端子连接机构主要包括容纳在装饰盒中的显示面板和设置在显示面板下端的端子部分，以接收由导电线固定的连接器。连接器在其一个侧壁面上设置有弹性定位板，其使得连接器能够可拆卸地固定在壳体中的适当位置。因此，根据本发明的端子连接机构可以为电致发光显示器提供显示面板与其导电线之间的连接和分离的便利性。具有行业实用价值。

12. 发明授权

US5919795A Biphenyl-2-carboxylic acid-tetrahydro-isoquinolin-6-yl amide derivatives, their preparation and their use as inhibitors of microsomal triglyceride transfer protein and/or apolipoprotein B (Apo B) secretion 失效
公开(公告)号：US5919795A
公开(公告)日：1999-07-06
申请号：US952507
申请日：1997-11-28
申请人： George Chang , Peter H. Dorff , George J. Quallich
发明人： George Chang , Peter H. Dorff , George J. Quallich
IPC分类号： A61K20060101 , A61K31/47 , A61K31/472 , A61K45/06 , A61P3/06 , A61P5/00 , A61P9/10 , C07C20060101 , C07C205/19 , C07C215/68 , C07C233/00 , C07C233/64 , C07C233/75 , C07D20060101 , C07D213/80 , C07D217/02 , C07D217/04 , C07D217/06 , C07D217/08 , C07D217/10 , C07D217/26 , C07D401/06 , C07D401/10 , C07D405/06 , C07D409/06 , C07D413/06 , C07D417/06 , A61K31/495
CPC分类号： C07D401/06 , C07D217/04 , C07D217/06 , C07D401/10 , C07D405/06 , C07D409/06 , C07D413/06 , C07D417/06
摘要： Compounds of formula (I), ##STR1## wherin X is CH.sub.2, CO, CS or SO.sub.2 ; Y is selected from: a direct link, aliphatic hydrocarbylene radicals having up to 20 carbon atoms, which radical may be mono-substituted by hydroxy, (C.sub.1 -C.sub.10)alkoxy, (C.sub.1 -C.sub.10)acyl, (C.sub.1 -C.sub.10)acyloxy, or (C.sub.6 -C.sub.10)aryl, NH, and O, provided that if X is CH.sub.2,Y is a direct link; Z is selected from the following groups: (1) H, halo, cyano, (2) hydroxy, (C.sub.1 -C.sub.10)alkoxy, (C.sub.1 -C.sub.10)a1kylthio, (C.sub.1 -C.sub.10)acyl, thiophenylcaronyl (C.sub.1 -C.sub.10)alkoxycarbonyl, (3) (C.sub.1 -C.sub.10)aklkyammo, di(C.sub.1 -C.sub.10)alylamino, (C.sub.6 -C.sub.10)aryl(C.sub.1 -C.sub.10)alkylamino, provided that Y is not O or NH, (4) unsubstituted vinyl, (C.sub.6 -C.sub.10)aryl, (C.sub.3 -C.sub.8)cycloalkyl and fused benz derivatives thereof, (C.sub.7 -C.sub.10)polycycloalkyl, (C.sub.4 -C.sub.8)cycloalkenyl, (C.sub.7 -C.sub.10)polycycloalkenyl, (5) (C.sub.6 -C.sub.10)aryloxy, (C.sub.6 -C.sub.10)aryltio, (C.sub.6 -C.sub.10)aryl(C.sub.1 -C.sub.10)alkoxy, (C.sub.6 -C.sub.10)aryl(C.sub.1 -C.sub.10)alkylthio, (C.sub.3 -C.sub.8)cycloalkyloxy, (C.sub.4 -C.sub.8)cycloalkenyloxy, (6) heterocyclyl sclected from the group consisting of monocyclic radicals and fused polycycuic radicals, wherein said radicals contain a total of from 5 to 14 ring atoms, wherein said radicals contain a total of from 1 to 4 ring heteroatoms independently selocted from oxygen, nitrogen, and sulfur, and wherein the individual rings of said radicals may be independendy satated, partally unsaturated, or aromatic, provided that if X is CH.sub.2, Z is H or is selected from groups (4) and (6), wherein, when Z contains one or more rings, said rings may each independently bear 0 to 4 substituents independently selected from halo, hydroxy, cyano, nitro, oxo, thioxo, aminosulfonyl, phenyl phenoxy, phenylthio, halophenylthio, benzyl, benzyloxy, (C.sub.1 -C.sub.10)alkyl, (C.sub.1 -C.sub.10)alkoxy, (C.sub.1 -C.sub.10)alkoxycarbonyl, (C.sub.1 -C.sub.10)althyltio, (C.sub.1 -C.sub.10)altylamino, (C.sub.1 -C.sub.10)alkylaminocarbonyl, di(C.sub.1 -C.sub.10)alkylamino, di(C.sub.1 -C.sub.10)alkylaminocarbonyl, di(C.sub.1 -C.sub.10)alkyo(C.sub.1 -C.sub.10)alkoxy, (C.sub.1 -C.sub.3)perfluoroalkyl, (C.sub.1 -C.sub.3)perfluoroalkoxy, (C.sub.1 -C.sub.10)acyl, (C.sub.1 -C.sub.10)acyloxy, (C.sub.1 -C.sub.10)acyloxy(C.sub.1 -C.sub.10)alkyl, and pyrrolidinyl; and pharmaceutically acceptable salts thereof.

13. 发明授权

US5656634A N-aryl and N-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme A: cholesterol acyl transferase (ACAT) 失效
标题翻译： N-芳基和N-杂芳基酰胺和脲衍生物作为酰基辅酶A的抑制剂：胆固醇酰基转移酶（ACAT）
公开(公告)号：US5656634A
公开(公告)日：1997-08-12
申请号：US251075
申请日：1994-05-31
申请人： George Chang , Ernest S. Hamanaka , Peter A. McCarthy , Thien V. Truong , Frederick J. Walker
发明人： George Chang , Ernest S. Hamanaka , Peter A. McCarthy , Thien V. Truong , Frederick J. Walker
IPC分类号： C07C233/25 , C07C233/58 , C07C233/59 , C07C233/60 , C07C235/24 , C07C275/34 , C07C317/44 , C07C323/52 , C07C323/60 , C07D213/73 , A61K31/44 , C07D213/38 , C07D239/42
CPC分类号： C07D213/73 , C07C233/25 , C07C233/58 , C07C233/59 , C07C233/60 , C07C235/24 , C07C275/34 , C07C317/44 , C07C323/52 , C07C323/60 , C07C2101/16 , C07C2102/08 , C07C2102/10 , C07C2102/42 , C07C2102/44
摘要： Compounds of the formula ##STR1## the pharmaceutically acceptable salts thereof, wherein Q and R.sup.1 are as defined below, and novel carboxylic acid and acid halide intermediates used in the synthesis of such compounds. The compounds of formula I are inhibitors of acyl coenzyme A: cholesterol acyltransferase (ACAT) and are useful as hypolipidemic and antiatherosclerosis agents.
摘要翻译：下式的化合物其中Q和R 1如下所定义，其中药学上可接受的盐，以及用于合成这些化合物的新的羧酸和酰卤中间体。式I化合物是酰基辅酶A：胆固醇酰基转移酶（ACAT）的抑制剂，可用作降血脂和抗动脉粥样硬化剂。

14. 发明授权

US5530803A Method and apparatus for programming memory devices 失效
标题翻译：用于编程存储器件的方法和装置
公开(公告)号：US5530803A
公开(公告)日：1996-06-25
申请号：US227755
申请日：1994-04-14
申请人： George Chang , Pearl Cheng
发明人： George Chang , Pearl Cheng
IPC分类号： G11C17/00 , G11C7/00 , G11C16/02 , G11C16/10 , G06F11/00
CPC分类号： G11C16/10
摘要： A method for programming an integrated memory circuit and an integrated memory circuit structure for storing information are disclosed. The method of programming includes the steps of providing a program mode for programming the memory cells in accordance with total number of memory cells that is required to be programmed; and programming the memory cells in accordance with the program mode. The integrated memory circuit includes a program mode determining circuit, and a programming circuit operatively coupled to the program mode determining circuit for programming each of a plurality of block of memory cells according to its respective program mode. The program mode determining circuit comprises a circuit for determining the total number of memory cells that is required to be programmed in each block and a control circuit operatively coupled to the memory cells determining circuit for providing a first program mode control signal, a plurality of second program mode control signals and a third program mode control signal, if the total number of memory cells that are required to be programmed in a block is greater than zero but is less than or equal to a threshold number N, greater than the threshold number N, and equal to zero, respectively. Through the use of the programming method and the integrated memory circuit design, the requirement of additional number or increased current capacities of drain pumps associated with programming the integrated circuit is eliminated which reduces design complexity and minimizes the size of the integrated circuit.
摘要翻译：公开了一种用于编程集成存储器电路的方法和用于存储信息的集成存储器电路结构。编程方法包括以下步骤：根据需要编程的存储器单元的总数来提供用于对存储器单元进行编程的编程模式; 并根据程序模式编程存储单元。集成存储器电路包括程序模式确定电路和可操作地耦合到程序模式确定电路的编程电路，用于根据其相应的程序模式对多个存储器单元块中的每一个进行编程。程序模式确定电路包括用于确定需要在每个程序段中编程的存储器单元的总数的电路和可操作地耦合到存储单元确定电路的控制电路，用于提供第一编程模式控制信号，多个第二程序模式控制信号和第三程序模式控制信号，如果要在块中编程的存储器单元的总数大于零但小于或等于阈值数N，则大于阈值数N ，并分别等于零。通过使用编程方法和集成存储器电路设计，消除了与编程集成电路相关联的排水泵的附加数量或增加的电流容量的要求，这降低了设计复杂性并使集成电路的尺寸最小化。

15. 发明授权

US5498786A Synthesis of intermediates in the preparation of ACAT inhibitors 失效
标题翻译：中间体在制备ACAT抑制剂中的合成
公开(公告)号：US5498786A
公开(公告)日：1996-03-12
申请号：US117109
申请日：1993-09-13
申请人： Sarah E. Kelly , George Chang
发明人： Sarah E. Kelly , George Chang
IPC分类号： C07C69/14 , A61K31/44 , A61K31/47 , C07C53/19 , C07C59/01 , C07C69/675 , C07C211/27 , C07C309/66 , C07C309/73 , C07C323/52 , C07C323/60 , C07D213/75 , C07D215/00 , C07D215/38 , C07D217/02 , C12P7/42 , C12P7/62 , C12P41/00 , C07C231/00
CPC分类号： C07D213/75 , C07C211/27 , C07C309/66 , C07C309/73 , C07C323/52 , C07C323/60 , C07C53/19 , C07C59/01 , C07D215/38
摘要： This invention relates to novel processes for synthesizing intermediates in the preparation of N-aryl and N-heteroarylamide inhibitors of the enzyme acyl coenzyme A: cholesterol acyltransferase (ACAT), and to novel intermediates used in such processes.
摘要翻译： PCT No.PCT / US91 / 08758 Sec。 371日期1993年9月13日 102（e）1993年9月13日PCT PCT 1991年11月27日PCT公布。公开号WO92 / 13843 本发明涉及在酰基辅酶A：胆固醇酰基转移酶（ACAT）的N-芳基和N-杂芳基酰胺抑制剂的制备中合成中间体的新方法，以及用于这些方法的新型中间体。

16. 发明申请

US20110192207A1 AUTOMATIC EXTRUSION DEVICE 失效
标题翻译：自动挤出装置
公开(公告)号：US20110192207A1
公开(公告)日：2011-08-11
申请号：US12763157
申请日：2010-04-19
申请人： Roger Huang , Newer Wang , George Chang , Jason Liao
发明人： Roger Huang , Newer Wang , George Chang , Jason Liao
IPC分类号： B21D41/02
CPC分类号： B21D41/021
摘要： An automatic extrusion device includes a main body, a driving unit, a first transmission unit, a second transmission unit and an extrusion unit. The second transmission unit has a clutch slip function for the automatic extrusion device to extrude the front of the pipe to be in the form of a bell for a fast connection of pipes. Through the slip function of the second transmission unit, it not only prevents the extrusion unit from over extrusion but also makes the front end of the pipe round so as to beautify the interface of the pipe.
摘要翻译：自动挤出装置包括主体，驱动单元，第一传动单元，第二传动单元和挤出单元。第二传动单元具有用于自动挤出装置的离合器打滑功能，以将管的前部挤出成为用于快速连接管道的钟形式。通过第二传动单元的滑动功能，不仅可以防止挤出单元过度挤压，而且使管的前端圆形，从而美化管道的界面。

17. 发明申请

US20090288679A1 Apparatus and method for cleaning surfaces 审中-公开
标题翻译：用于清洁表面的设备和方法
公开(公告)号：US20090288679A1
公开(公告)日：2009-11-26
申请号：US12454764
申请日：2009-05-22
申请人： Anton Pietsch , George Lynch , Kevin Lynch , George Chang
发明人： Anton Pietsch , George Lynch , Kevin Lynch , George Chang
IPC分类号： B08B3/12 , B08B3/00
CPC分类号： B08B3/12 , B08B5/00 , F24S40/20 , Y02E10/40
摘要： The apparatus for cleaning surfaces of the present invention such as for cleaning solar collectors preferably alternates different fluids and gas decompression to create a cleansing fluid evacuation to clean outdoor solid surfaces. The method of the present invention utilizes alternating fluids in order to avoid mineral deposits contaminating the collector. The apparatus of the present invention is a tool to achieve the ends of the method. The apparatus preferably uses copper piping and turbulence to regulate water flow and to create the high velocity fluid evacuation that achieves the ends of the method invention. The use of a constant pressure pump and turbulence inducing fibers allows passive regulation of pressure that is equalized across a plurality of sprayers to deliver an even amount of high velocity fluid from each sprayer. Sonication accelerates cleaning, rinsing or snow/ice removal.
摘要翻译：用于清洁本发明的表面的装置，例如用于清洁太阳能收集器的装置优选地替换不同的流体和气体减压，以产生清洁流体抽真空以清洁室外固体表面。本发明的方法利用交替流体，以避免矿物沉积物污染收集器。本发明的装置是实现该方法的目的的工具。该装置优选使用铜管道和湍流来调节水流并产生实现方法发明端点的高速流体抽空。使用恒压泵和湍流诱导纤维允许被动地调节在多个喷雾器之间相等的压力，以从每个喷雾器输送均匀量的高速流体。超声处理加速清洁，冲洗或除冰/除冰。

18. 发明申请

US20060122224A1 Quinoline and quinoxaline compounds 审中-公开
标题翻译：喹啉和喹喔啉化合物
公开(公告)号：US20060122224A1
公开(公告)日：2006-06-08
申请号：US11305874
申请日：2005-12-15
申请人： Bruce Bechle , George Chang , Mary Diduik , Jari Finneman , Ravi Garigipati , Rayn Kelley , David Perry , Michael Pollastri , Roger Ruggeri
发明人： Bruce Bechle , George Chang , Mary Diduik , Jari Finneman , Ravi Garigipati , Rayn Kelley , David Perry , Michael Pollastri , Roger Ruggeri
IPC分类号： A61K31/47 , C07D215/38
CPC分类号： C07D401/04 , C07D215/12 , C07D215/14 , C07D241/42 , C07D401/06 , C07D401/12 , C07D403/06 , C07D403/10 , C07D405/06 , C07D405/12 , C07D409/06 , C07D409/12 , C07D413/06 , C07D413/10 , C07D413/12 , C07D417/06 , C07D417/12 , C07D417/14 , C07D471/04 , C07D495/04
摘要： Quinoline and quinoxaline compounds, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.
摘要翻译：喹啉和喹喔啉化合物，含有这些化合物的药物组合物以及使用这些化合物来提高某些血浆脂质水平，包括高密度脂蛋白胆固醇和降低某些其他血浆脂质水平，如低密度脂蛋白胆固醇和甘油三酸酯，从而治疗疾病这些由于低水平的HDL胆固醇和/或高水平的LDL-胆固醇和甘油三酸酯而加剧，如一些哺乳动物，包括人类的动脉粥样硬化和心血管疾病。

19. 发明申请

US20060039216A1 INTEGRATED CIRCUIT MEMORY DEVICE WITH BIT LINE PRE-CHARGING BASED UPON PARTIAL ADDRESS DECORDING 有权
标题翻译：具有位线预充电的集成电路存储器件基于部分地址判定
公开(公告)号：US20060039216A1
公开(公告)日：2006-02-23
申请号：US10893809
申请日：2004-07-19
申请人： Neal Berger , George Chang , Pearl Cheng , Anne Koh
发明人： Neal Berger , George Chang , Pearl Cheng , Anne Koh
IPC分类号： G11C7/00
CPC分类号： G11C7/12
摘要： An integrated circuit memory device has an array of memory cells arranged in a plurality of rows and columns and a plurality of row lines and a plurality of column lines. Cells arranged in the same row are connected by a common row line, and cells arranged in the same column are connected by a common column line. Each cell in the array is addressed by an address signal which has a plurality of bits. A sense amplifier circuit is connectable to one or more of the plurality of column lines of the array. An address input terminal receives in series the plurality of bits of the address signal. Each of the column lines is connectable to a pre-charge voltage, in response to a read command. A decoder circuit receives the address signal and decodes the address signal as each of the plurality of bits is received and disconnects certain of the column lines to the pre-charge voltage in response to the decoding, and activates the sense amplifier circuit after all of the plurality of bits of the address signal are received.
摘要翻译：集成电路存储器件具有排列成多个行和列以及多条行线和多条列线的存储单元阵列。布置在同一行中的单元通过公共行线连接，并且排列在同一列中的单元通过公共列线连接。阵列中的每个单元由具有多个位的地址信号来寻址。读出放大器电路可连接到阵列的多个列线中的一个或多个。地址输入端串联地址信号的多个位。响应读取命令，每列列线可连接到预充电电压。解码器电路接收地址信号并且在接收到多个比特中的每一个时对地址信号进行解码，并且响应于解码将某些列线断开到预充电电压，并且在全部接收地址信号的多个位。

20. 发明授权

US6121283A Apo B-secretion/MTP inhibitory amides 失效
标题翻译： Apo B分泌/ MTP抑制酰胺
公开(公告)号：US6121283A
公开(公告)日：2000-09-19
申请号：US284466
申请日：1999-04-20
申请人： George Chang , George Joseph Quallich
发明人： George Chang , George Joseph Quallich
IPC分类号： C07D217/22 , A61K31/47 , A61K31/472 , A61K31/4725 , A61K31/496 , A61K31/5377 , A61P3/04 , A61P3/06 , A61P3/10 , A61P43/00 , C07D217/04 , C07D401/04 , C07D401/06 , C07D405/04 , C07D405/06 , C07D409/06 , C07D417/06
CPC分类号： C07D401/04 , C07D217/04 , C07D401/06 , C07D405/04 , C07D405/06 , C07D409/06 , C07D417/06
摘要： This invention is directed to compounds of formula (I) or the stereoisomers, pharmaceutically acceptable salts and hydrates thereof. The compounds are Apo B/MTP inhibitors and are useful in the treatment of various disorders and conditions such as atherosclerosis, pancreatitis, obesity, hypercholesteremia, hypertriglyceridemia, hyperlipidemia, and diabetes. The compounds of this invention are also useful in combination with other pharmaceutical agents including cholesterol biosynthesis inhibitors and cholesterol absorption inhibitors,especially HMG-CoA reductase inhibitors and HMG-CoA synthase inhibitors; HMG-CoA reductase gene expression inhibitors; CETP inhibitors; bile acid sequestrants; fibrates; cholesterol absorption inhibitors; ACAT inhibitors, squalene synthetase inhibitors, ion-exchange resins, anti-oxidants and niacin. This invention is also directed to intermediates and processes useful in the preparation of compounds of formula (I) ##STR1##
摘要翻译： PCT No.PCT / IB97 / 01368 Sec。 371日期1999年4月20日 102（e）1999年4月20日PCT PCT 1997年11月3日PCT公布。第WO98 / 23593号公报日期1998年6月4日本发明涉及式（I）化合物或其立体异构体，其药学上可接受的盐和水合物。这些化合物是Apo B / MTP抑制剂，可用于治疗各种疾病和病症如动脉粥样硬化，胰腺炎，肥胖症，高胆固醇血症，高甘油三酯血症，高脂血症和糖尿病。本发明的化合物还可与其它药剂组合使用，包括胆固醇生物合成抑制剂和胆固醇吸收抑制剂，特别是HMG-CoA还原酶抑制剂和HMG-CoA合成酶抑制剂; HMG-CoA还原酶基因表达抑制剂; CETP抑制剂; 胆汁酸螯合剂贝特类胆固醇吸收抑制剂; ACAT抑制剂，角鲨烯合成酶抑制剂，离子交换树脂，抗氧化剂和烟酸。本发明还涉及可用于制备式（I）化合物的中间体和方法，

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式