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11. 发明授权

US06726818B2 Biosensors with porous chromatographic membranes 失效
标题翻译：生物传感器与多孔色谱膜
公开(公告)号：US06726818B2
公开(公告)日：2004-04-27
申请号：US09904930
申请日：2001-07-13
申请人： Gang Cui , Jae Hyun Yoo , Byung Wook Woo , Moon Hwan Kim , Hyun Joon Oh , Hakhyun Nam , Geun Sig Cha
发明人： Gang Cui , Jae Hyun Yoo , Byung Wook Woo , Moon Hwan Kim , Hyun Joon Oh , Hakhyun Nam , Geun Sig Cha
IPC分类号： G01N27327
CPC分类号： G01N27/3272 , C12Q1/004 , C12Q1/006 , C12Q1/26 , G01N30/90 , G01N33/491
摘要： Disclosed is a porous membrane built-in biosensor comprising (a) at least one substrate; (b) an electrode layer patterned on the substrate, consisting of an electrode system and a circuit connector; (c) an insulator, formed on parts of the electrode layer, for electrically separating the electrode system from a circuit connector; and (d) a porous membrane via the insulator on the electrode system, wherein, when a whole blood sample is introduced to the biosensor, the whole blood sample is separated into its components during the chromatographic motion through the porous membrane so that only blood plasma can be contacted with the electrode system. The porous membrane built-in biosensor is provided with a sample inlet, which allows samples to be introduced in a constant quantity to the biosensors porous membranes without pretreatment.
摘要翻译：公开了一种内置多孔膜的生物传感器，其包含（a）至少一个基底; （b）在基板上图案化的电极层，由电极系统和电路连接器组成; （c）形成在所述电极层的部分上的用于将所述电极系统与电路连接器电分离的绝缘体; 和（d）通过电极系统上的绝缘体的多孔膜，其中当将全血样品引入生物传感器时，在通过多孔膜进行色谱运动期间将全血样品分离成其组分，使得仅血浆可以与电极系统接触。多孔膜内置生物传感器具有样品入口，其允许将样品以恒定量引入生物传感器多孔膜而无需预处理。

12. 发明授权

US07695608B2 Electrochemical biosensor and biosensor measuring device 有权
标题翻译：电化学生物传感器和生物传感器测量装置
公开(公告)号：US07695608B2
公开(公告)日：2010-04-13
申请号：US11747945
申请日：2007-05-14
申请人： Keun Ki Kim , Jae Hyun Yoo , Gang Cui , Moon Hwan Kim , Hakhyun Nam , Geun Sig Cha
发明人： Keun Ki Kim , Jae Hyun Yoo , Gang Cui , Moon Hwan Kim , Hakhyun Nam , Geun Sig Cha
IPC分类号： G01N27/403 , G01N27/327 , G01N21/00 , G06K9/36 , G03B7/08
CPC分类号： B01L3/545 , B01L3/5027 , B01L2300/0645 , B01L2300/0825 , B01L2300/0887 , B01L2400/0406 , G01N27/3272 , G01N35/00732 , G01N2035/00772 , G01N2035/00851
摘要： An electrochemical biosensor and a biosensor measuring device. The electrochemical biosensor includes a plurality of electrodes, capillary sample cell portions, reaction reagent layers, electrode connection portions, and a production lot information identification portion. The production lot information identification portion is configured such that the production lot information is recorded thereon has one or more infrared absorption/reflection marks, which indicate information about differences between production lots through the printing and/or attachment of colored or colorless materials, having differences in absorbency or reflectivity of infrared rays, in conformity of a predetermined pattern or through the attachment of transparent films. The electrochemical biosensor measuring device includes a plurality of integrated photo-reflector sensing devices that emit and receive infrared rays to identify the production lot information recorded on the production lot information identification portion of the biosensor.
摘要翻译：电化学生物传感器和生物传感器测量装置。电化学生物传感器包括多个电极，毛细管样品池部分，反应试剂层，电极连接部分和生产批次信息识别部分。生产批次信息识别部被配置为使得生产批次信息被记录在其上，具有一个或多个红外吸收/反射标记，其表示通过有色或无色材料的印刷和/或附着的生产批次之间的差异的信息，其具有差异红外线的吸收性或反射率，符合预定图案或通过透明膜的附着。电化学生物传感器测量装置包括发射和接收红外线的多个集成光反射器感测装置，以识别记录在生物传感器的生产批次信息识别部分上的生产批次信息。

13. 发明授权

US09512458B2 Electrochemical biosensor with sample introduction channel capable of uniform introduction of small amount of sample 有权
标题翻译：电化学生物传感器，样品引入通道能均匀引入少量样品
公开(公告)号：US09512458B2
公开(公告)日：2016-12-06
申请号：US12740016
申请日：2008-10-24
申请人： Gang Cui , Jae Hyun Yoo , Ju Yong Kim , Keun Ki Kim , Moon Hwan Kim , Hakhyun Nam , Geun Sig Cha
发明人： Gang Cui , Jae Hyun Yoo , Ju Yong Kim , Keun Ki Kim , Moon Hwan Kim , Hakhyun Nam , Geun Sig Cha
IPC分类号： C12Q1/00 , G01N27/327 , B01L3/00
CPC分类号： C12Q1/006 , B01L3/5027 , B01L2300/0645 , B01L2300/0825 , B01L2300/0887 , B01L2400/0406 , G01N27/3272
摘要： Disclosed is an electrochemical biosensor having a sample introduction channel in which an insulator is employed to introduce a small amount of a sample uniformly and accurately and to adjust an area of a working electrode, thereby guaranteeing the accurate quantitative analysis of a sample. Provided with a sample collection barrier at a sample entrance, the biosensor allows a sample to be introduced at higher accuracy and to be analyzed with higher reproducibility and reliability.
摘要翻译：公开了一种具有样品导入通道的电化学生物传感器，其中采用绝缘体均匀且准确地引入少量样品并调节工作电极的面积，从而保证了样品的准确定量分析。在样品入口处提供样品收集屏障，生物传感器允许以更高的精度引入样品并以更高的再现性和可靠性进行分析。

14. 发明申请

US20080237062A1 Electrochemical biosensor and biosensor measuring device 有权
标题翻译：电化学生物传感器和生物传感器测量装置
公开(公告)号：US20080237062A1
公开(公告)日：2008-10-02
申请号：US11747945
申请日：2007-05-14
申请人： Keun Ki Kim , Jae Hyun Yoo , Gang Cui , Moon Hwan Kim , Hakhyun Nam , Geun Sig Cha
发明人： Keun Ki Kim , Jae Hyun Yoo , Gang Cui , Moon Hwan Kim , Hakhyun Nam , Geun Sig Cha
IPC分类号： C12Q1/00
CPC分类号： B01L3/545 , B01L3/5027 , B01L2300/0645 , B01L2300/0825 , B01L2300/0887 , B01L2400/0406 , G01N27/3272 , G01N35/00732 , G01N2035/00772 , G01N2035/00851
摘要： An electrochemical biosensor and a biosensor measuring device. The electrochemical biosensor includes a plurality of electrodes, capillary sample cell portions, reaction reagent layers, electrode connection portions, and a production lot information identification portion. The production lot information identification portion is configured such that the production lot information is recorded thereon has one or more infrared absorption/reflection marks, which indicate information about differences between production lots through the printing and/or attachment of colored or colorless materials, having differences in absorbency or reflectivity of infrared rays, in conformity of a predetermined pattern or through the attachment of transparent films. The electrochemical biosensor measuring device includes a plurality of integrated photo-reflector sensing devices that emit and receive infrared rays to identify the production lot information recorded on the production lot information identification portion of the biosensor.
摘要翻译：电化学生物传感器和生物传感器测量装置。电化学生物传感器包括多个电极，毛细管样品池部分，反应试剂层，电极连接部分和生产批次信息识别部分。生产批次信息识别部被配置为使得生产批次信息被记录在其上，具有一个或多个红外吸收/反射标记，其表示通过有色或无色材料的印刷和/或附着的生产批次之间的差异的信息，其具有差异红外线的吸收性或反射率，符合预定图案或通过透明膜的附着。电化学生物传感器测量装置包括发射和接收红外线的多个集成光反射器感测装置，以识别记录在生物传感器的生产批次信息识别部分上的生产批次信息。

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