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11. 发明申请

US20090098291A1 METHOD OF PRODUCING SOLID SUPPORT FOR BIOLOGICAL ANALYSIS USING PLASTIC MATERIAL 审中-公开
标题翻译：使用塑料材料生产生物分析的固体支持方法
公开(公告)号：US20090098291A1
公开(公告)日：2009-04-16
申请号：US12100700
申请日：2008-04-10
申请人： Kyu-youn HWANG , Joon-ho Kim , Sung-young Jeong , Chin-sung Park
发明人： Kyu-youn HWANG , Joon-ho Kim , Sung-young Jeong , Chin-sung Park
IPC分类号： C23C16/44 , B05D1/36
CPC分类号： G01N33/54353 , C23C14/025 , C23C14/028 , C23C14/10 , G01N33/553
摘要： The present invention provides a method of manufacturing a solid support for biological analysis using a plastic material, the method including: depositing a metal film on a plastic substrate on which a microstructure is formed; depositing an inorganic oxide on the metal film; and anchoring a compound with an amino functional group or a compound with a water contact angle of 70 to 95 degrees on the inorganic oxide.
摘要翻译：本发明提供一种使用塑料材料制造用于生物分析的固体支持物的方法，所述方法包括：在形成微结构的塑料基板上沉积金属膜; 在金属膜上沉积无机氧化物; 并且将具有氨基官能团的化合物或具有70至95度的水接触角的化合物锚定在无机氧化物上。

12. 发明申请

US20080305011A1 MICROFLUIDIC CHIP AND METHOD OF FABRICATING THE SAME 有权
标题翻译：微流控芯片及其制造方法
公开(公告)号：US20080305011A1
公开(公告)日：2008-12-11
申请号：US11934811
申请日：2007-11-05
申请人： Kyu-youn HWANG , Joon-ho Kim , Chin-sung Park , Sung-young Jeong
发明人： Kyu-youn HWANG , Joon-ho Kim , Chin-sung Park , Sung-young Jeong
IPC分类号： B44C1/22 , B01L3/00 , G03C5/00
CPC分类号： B01L3/502707 , B01L3/502753 , B01L2200/12 , B01L2300/16 , Y10T428/14
摘要： Provided are a microfluidic chip and a method of fabricating the same. The microfluidic chip includes: a lower substrate; an upper substrate formed of a silicone resin, wherein the lower substrate and the upper substrate, bonded together, provide a channel through which a fluid can flow and a chamber to receive the fluid; and an organic thin film formed on the upper surface of the lower substrate except for portions on which the lower substrate and the upper substrate are attached to each other.
摘要翻译：提供了一种微流控芯片及其制造方法。微流体芯片包括：下基板; 由硅树脂形成的上基板，其中所述下基板和所述上基板接合在一起，提供流体可以流过的通道和容纳所述流体的室; 以及形成在下基板的上表面上的有机薄膜，除了下基板和上基板彼此附接的部分之外。

13. 发明授权

US08557564B2 Method of separating microorganism using nonplanar solid substrate and device for separating microorganism using the same 有权
标题翻译：使用非平面固体底物分离微生物的方法和使用其分离微生物的装置
公开(公告)号：US08557564B2
公开(公告)日：2013-10-15
申请号：US13325980
申请日：2011-12-14
申请人： Kyu-youn Hwang , Sung-young Jeong , Joon-ho Kim
发明人： Kyu-youn Hwang , Sung-young Jeong , Joon-ho Kim
IPC分类号： C12N1/02
CPC分类号： C12N1/02 , B01J39/02 , B01J39/14
摘要： Provided is a method of separating microorganisms from a sample including contacting the sample containing microorganisms with an inorganic on exchange material such that the sample reacts with the inorganic on exchange material, and contacting the reacted sample with a means for capturing microorganisms.
摘要翻译：提供了一种从样品中分离微生物的方法，包括使含有微生物的样品与交换材料上的无机物接触，使得样品与无机的交换材料反应，并使反应的样品与捕获微生物的装置接触。

14. 发明授权

US08158411B2 Method of separating microorganism using nonplanar solid substrate and device for separating microorganism using the same 有权
标题翻译：使用非平面固体底物分离微生物的方法和使用其分离微生物的装置
公开(公告)号：US08158411B2
公开(公告)日：2012-04-17
申请号：US11841117
申请日：2007-08-20
申请人： Kyu-youn Hwang , Sung-young Jeong , Joon-ho Kim
发明人： Kyu-youn Hwang , Sung-young Jeong , Joon-ho Kim
IPC分类号： C12M1/00
CPC分类号： C12N1/02 , B01J39/02 , B01J39/14
摘要： Provided is a method of separating microorganisms from a sample including contacting the sample containing microorganisms with an inorganic ion exchange material such that the sample reacts with the inorganic ion exchange material, and contacting the reacted sample with a means for capturing microorganisms.
摘要翻译：提供了从样品中分离微生物的方法，包括使含有微生物的样品与无机离子交换材料接触，使得样品与无机离子交换材料反应，并使反应的样品与捕获微生物的方法接触。

15. 发明授权

US08343330B2 Microfluidic device for electrochemically regulating pH of fluid and method of regulating pH of fluid using the microfluidic device 有权
标题翻译：用于电化学调节流体pH的微流体装置和使用微流体装置调节流体pH的方法
公开(公告)号：US08343330B2
公开(公告)日：2013-01-01
申请号：US11558940
申请日：2006-11-13
申请人： Hun-joo Lee , Joon-ho Kim , Sung-young Jeong , Hee-kyun Lim
发明人： Hun-joo Lee , Joon-ho Kim , Sung-young Jeong , Hee-kyun Lim
IPC分类号： C25B9/00 , C02F1/461 , C02F1/66
CPC分类号： B01D61/44 , B01L3/502707 , B01L2200/0684 , B01L2300/10 , B01L2400/0487
摘要： A microfluidic device which electrochemically regulates a pH of a fluid, and a method of regulating a pH of a fluid using the microfluidic device, include a chamber which includes a cathode formed of a metal adsorbing hydrogen gas, and an anode formed of a metal having a higher standard oxidation potential than, and does not react with, water.
摘要翻译：电化学调节流体pH值的微流体装置以及使用微流体装置调节流体pH值的方法包括：包含由吸附氢气的金属形成的阴极的室和由金属形成的阳极，比水更高的标准氧化电位，并且不与水反应。

16. 发明授权

US08524059B2 Apparatus and method for adjusting pH of solution 有权
标题翻译：调节溶液pH值的装置和方法
公开(公告)号：US08524059B2
公开(公告)日：2013-09-03
申请号：US13495342
申请日：2012-06-13
申请人： Hun joo Lee , Jin tae Kim , Sung-young Jeong , Joon-ho Kim , Hee-kyun Lim
发明人： Hun joo Lee , Jin tae Kim , Sung-young Jeong , Joon-ho Kim , Hee-kyun Lim
IPC分类号： G01N27/44
CPC分类号： G05D21/02
摘要： A pH adjusting apparatus includes an electrolytic chip receiving a solution, an electrolytic chip loading station receiving the electrolytic chip, an input unit inputting electrolysis conditions, a control unit receiving the electrolysis conditions and controlling electrolysis performed in the electrolytic chip, and a display unit displaying the electrolysis conditions and a progress of the electrolysis. Thus, the pH of a solution can be adjusted easily and accurately, by precisely controlling a constant current, a constant voltage, and current and voltage application times, thereby enabling useful application in various biological assays such as cell lysis. Furthermore, the pH adjusting apparatus has small size and weight and can be operated for a long time after charging once due to low power consumption.
摘要翻译： pH调节装置包括：接收溶液的电解芯片，接收电解芯片的电解芯片装载站，输入电解条件的输入单元，接收电解条件的控制单元以及控制电解芯片中进行的电解;以及显示单元，电解条件和电解进度。因此，通过精确地控制恒定电流，恒定电压，电流和电压施加时间，可以容易且精确地调节溶液的pH，从而可用于各种生物测定如细胞裂解中的有用应用。此外，pH调节装置的体积小，重量轻，能够在低功耗的情况下一次充电后长时间运转。

17. 发明授权

US07837943B2 Device and method for pre-treating and injecting liquid specimen 有权
标题翻译：预处理和注射液体样品的装置和方法
公开(公告)号：US07837943B2
公开(公告)日：2010-11-23
申请号：US11484068
申请日：2006-07-11
申请人： Sung-young Jeong , Hun-joo Lee
发明人： Sung-young Jeong , Hun-joo Lee
IPC分类号： A61M5/19 , A61M5/315
CPC分类号： G01N1/14 , G01N1/405
摘要： A device for pre-treating and injecting a liquid specimen includes a first syringe including an open top first tube including a first hole in the bottom and protrusions, a second syringe including an open top second tube including a second hole in the bottom and an inner diameter greater than an outer diameter of the first tube, a second piston movable along an inner wall of the second tube and including a third hole and a communication channel providing fluid communication between the first hole and the third hole, and a joint portion attachable to and detachable from a top of the second tube and including an opening corresponding to a transverse cross-section of the first tube and grooves corresponding to the shape of the protrusions such that the first tube passes through the joint portion when the protrusions are matched with the grooves.
摘要翻译：一种用于预处理和注射液体试样的装置包括：第一注射器，其包括开口顶部第一管，其包括底部中的第一孔和突起;第二注射器，其包括开口顶部第二管，其包括底部中的第二孔，直径大于第一管的外径，第二活塞可沿着第二管的内壁移动并且包括第三孔和提供第一孔和第三孔之间的流体连通的连通通道，以及连接部分，其可附接到并且可从第二管的顶部拆卸并且包括对应于第一管的横截面的开口和对应于突起的形状的槽，使得当突起与第二管匹配时，第一管穿过接合部凹槽

18. 发明申请

US20070163366A1 Device and method for pre-treating and injecting liquid specimen 有权
标题翻译：预处理和注射液体样品的装置和方法
公开(公告)号：US20070163366A1
公开(公告)日：2007-07-19
申请号：US11484068
申请日：2006-07-11
申请人： Sung-young Jeong , Hun-joo Lee
发明人： Sung-young Jeong , Hun-joo Lee
IPC分类号： G01N1/00
CPC分类号： G01N1/14 , G01N1/405
摘要： Provided are a device and a method for pre-treating and injecting a liquid specimen. The device includes a first syringe comprising: a first tube having an open top and a first hole in the bottom; and protrusions formed in a lower and outer wall of the first tube; a second syringe comprising: a second tube having an open top and a second hole in the bottom and having an inner diameter greater than an outer diameter of the first tube; a second piston capable of moving along an inner wall of the second tube and having a third hole; and a communication channel providing a fluid communication between the first hole of the first tube and the third hole of the second piston and fixing the second piston to the first tube; and a joint portion being attachable to and detachable from a top of the second tube and having an opening having a shape which corresponds to a transverse cross-section of the first tube and grooves having a shape which corresponds to the shape of the protrusions such that the first tube can pass through the joint portion when the protrusions are matched with the grooves.
摘要翻译：提供了用于预处理和注射液体样本的装置和方法。该装置包括第一注射器，其包括：第一管，其具有开口顶部和底部中的第一孔; 以及形成在所述第一管的下壁和外壁中的突起; 第二注射器，包括：第二管，其在底部具有开口顶部和第二孔，并且具有大于第一管的外径的内径; 第二活塞，其能够沿着所述第二管的内壁移动并具有第三孔; 以及连通通道，其在所述第一管的所述第一孔和所述第二活塞的所述第三孔之间提供流体连通并将所述第二活塞固定到所述第一管; 以及接合部，其可连接到所述第二管的顶部并且可从所述第二管的顶部拆卸，并具有具有对应于所述第一管的横截面的形状的开口和具有对应于所述突起的形状的形状的开口，使得当突起与槽匹配时，第一管可以穿过接合部。

19. 发明授权

US07989197B2 Microfluidic device including a microchannel with a hydrophobic porous polymer bonded to walls thereof and to a magnetic bead, and methods of making and using the device 有权
标题翻译：微流体装置包括具有与其壁连接的疏水多孔聚合物的微通道和磁珠，以及制造和使用该装置的方法
公开(公告)号：US07989197B2
公开(公告)日：2011-08-02
申请号：US11675840
申请日：2007-02-16
申请人： Chang-eun Yoo , Jong-myeon Park , Sung-young Jeong
发明人： Chang-eun Yoo , Jong-myeon Park , Sung-young Jeong
IPC分类号： C12M1/34
CPC分类号： C12M47/06 , B01L3/502761 , B01L7/52 , B01L2200/0631 , B01L2200/0668 , B01L2200/10 , B01L2300/069 , B01L2300/087 , B01L2300/165 , B01L2300/18 , B01L2400/043 , C12M23/16
摘要： This invention provides a microfluidic device comprising an inlet and an outlet which are connected with each other through a microchannel, wherein a polymerized hydrophobic porous polymer is bonded to magnetic beads and to the walls of the microchannel. The invention is further directed to methods of making and using the microfluidic device.
摘要翻译：本发明提供了一种微流体装置，其包括通过微通道彼此连接的入口和出口，其中聚合的疏水性多孔聚合物结合到磁珠和微通道的壁上。本发明进一步涉及制造和使用微流体装置的方法。

20. 发明申请

US20110129481A1 Antibody specifically binding to c-Met and methods of use 有权
标题翻译：抗体特异性结合c-Met和使用方法
公开(公告)号：US20110129481A1
公开(公告)日：2011-06-02
申请号：US12807191
申请日：2010-08-30
申请人： Kwang Ho Cheong , Sung-young Jeong , Sang-hyun Paek
发明人： Kwang Ho Cheong , Sung-young Jeong , Sang-hyun Paek
IPC分类号： A61K39/395 , C07K16/28 , C07H21/04 , C12N15/63 , C12N1/21 , C12N5/12 , G01N33/53 , A61P35/00 , C12N5/10 , C12N1/19
CPC分类号： G01N33/57407 , C07K16/2863 , C07K2317/33 , G01N33/57492
摘要： Antibodies specifically binding to c-Met protein, hybridoma cell lines, and compositions comprising the antibodies are disclosed herein. Methods of making and using the antibodies and compositions are also disclosed.
摘要翻译：本文公开了与c-Met蛋白，杂交瘤细胞系以及包含抗体的组合特异性结合的抗体。还公开了制备和使用抗体和组合物的方法。

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