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    • 11. 发明授权
    • Arterial-pulse-wave detecting apparatus
    • 动脉脉波检测装置
    • US06758820B2
    • 2004-07-06
    • US10265396
    • 2002-10-07
    • Kiyoyuki NarimatsuToshihiko Ogura
    • Kiyoyuki NarimatsuToshihiko Ogura
    • A61O502
    • A61B5/022A61B5/02A61B5/02255A61B5/0285
    • An arterial-pulse-wave detecting apparatus, including a plurality of pulse-wave detecting devices which are adapted to be worn on a plurality of portions of a living subject, respectively, and detect respective pulse waves that are produced in synchronism with each other from respective arteries of the plurality of portions of the subject, a memory device which stores the respective pulse waves produced in synchronism with each other and detected by the plurality of pulse-wave detecting devices, and a pulse-wave-display control device for controlling a display device to display the respective pulse waves produced in synchronism with each other and stored by the memory device, such that the respective pulse waves are superposed on each other.
    • 一种动脉脉波检测装置,包括分别适于佩戴在活体的多个部分上的多个脉波检测装置,并且检测相互同步产生的各个脉搏波 被检体的多个部分的各自的动脉,存储由多个脉波检测装置检测的彼此同步产生的各脉波的存储装置,以及用于控制多个脉波检测装置的脉波显示控制装置 显示装置,以显示彼此同步并由存储装置存储的相应脉冲波,使得各个脉冲波彼此重叠。
    • 12. 发明授权
    • Arteriosclerosis evaluating apparatus
    • 动脉硬化评估仪
    • US06612993B2
    • 2003-09-02
    • US10076502
    • 2002-02-19
    • Kiyoyuki Narimatsu
    • Kiyoyuki Narimatsu
    • A61B500
    • A61B5/0285A61B5/02A61B5/7239
    • An apparatus for evaluating a degree of arteriosclerosis of a living subject, including a pulse-wave-propagation-velocity-related-information obtaining device which obtains pulse-wave-propagation-velocity-related information that is related to a velocity at which a pulse wave propagates in the subject, a pulse-wave sensor which is adapted to be worn on a body portion of the subject and detects the pulse wave from the body portion, an augmentation-related-information obtaining device for obtaining augmentation-related information that is related to an augmentation of an amplitude of the pulse wave detected by the pulse-wave sensor from an amplitude of an incident-wave component which is contained in the pulse wave, and an arteriosclerosis evaluating device for evaluating the degree of arteriosclerosis of the subject, based on the pulse-wave-propagation-velocity-related information obtained by the pulse-wave-propagation-velocity-related-information obtaining device and the augmentation-related information obtained by the augmentation-related-information obtaining device, according to a prescribed relationship between (A) (a1) pulse-wave-propagation-velocity-related information and (a2) augmentation-related information and (B) degree of arteriosclerosis.
    • 一种用于评估生物体的动脉硬化程度的装置,包括脉搏波传播速度相关信息获取装置,该装置获得脉冲波传播速度相关信息,该脉冲波传播速度相关信息与脉冲 波在对象中传播,适用于佩戴在被检体的身体部位并检测来自身体部位的脉搏波的脉搏波传感器,用于获取增强相关信息的增强相关信息获取装置, 涉及由包含在脉搏波中的入射波分量的振幅增加由脉搏波传感器检测到的脉搏波的振幅;以及动脉硬化评价装置,用于评价对象的动脉硬化程度, 基于由脉搏波传播速度相关信息获取装置获得的脉搏波传播速度相关信息和增强r (A)(a1)脉搏波传播速度相关信息和(a2)增强相关信息和(B)动脉硬化程度之间的规定关系,由增强相关信息获取装置获得的兴奋信息 。
    • 13. 发明授权
    • Non-invasive and continuous blood-pressure estimation apparatus
    • 无创和连续血压估测仪
    • US06186953B1
    • 2001-02-13
    • US09398457
    • 1999-09-17
    • Kiyoyuki Narimatsu
    • Kiyoyuki Narimatsu
    • A61B502
    • A61B5/02125A61B5/02225A61B5/02255A61B5/0285A61B5/7264A61B5/7267Y10S128/925
    • An apparatus for iteratively estimating an intra-arterial blood-pressure value of a living subject, including a first information obtaining device which non-invasively and iteratively obtains information relating to propagation of a pulse wave through an arterial vessel of the subject, a second information obtaining device which non-invasively and iteratively obtains information relating to heartbeat of the subject and/or information relating to area of a heartbeat-synchronous pulse of a volumetric pulse wave obtained from a peripheral body portion of the subject, and an estimating device including a neural network which learns sets of information each set of which includes a blood-pressure value measured using a cuff, pulse-wave-propagation-relating information obtained when the blood-pressure value is measured using the cuff, and heartbeat-relating information and/or pulse-wave-area-relating information obtained when the blood-pressure value is measured using the cuff, the neural network iteratively estimating an intra-arterial blood-pressure value of the subject, based on each piece of pulse-wave-propagation-relating information iteratively obtained by the first information obtaining device, and each piece of heartbeat-relating information and/or each piece of pulse-wave-area-relating information which are or is iteratively obtained by the second information obtaining device.
    • 一种用于迭代地估计活体的动脉内血压值的装置,包括第一信息获取装置,其非侵入性地迭代地获得与所述对象的动脉血管的脉搏波的传播有关的信息,第二信息 获取装置,其非侵入地且迭代地获得与被检体的心跳相关的信息和/或与从被检体的周边体部获得的体积脉搏波的心跳同步脉冲的面积有关的信息,以及估计装置, 学习各组信息的神经网络,其包括使用袖带测量的血压值,当使用袖带测量血压值时获得的脉搏波传播相关信息和心跳相关信息和/ 或使用袖带测量血压值时获得的脉搏波区域相关信息,即神经网络 基于由第一信息获取装置迭代获得的每条脉搏波传播相关信息和每条心跳相关信息和/或每个片段,迭代地估计对象的动脉内血压值 由第二信息获取装置反复获得的脉波区域相关信息。
    • 14. 发明授权
    • Pressure pulse wave detecting apparatus
    • 压力脉波检测装置
    • US5762610A
    • 1998-06-09
    • US675675
    • 1996-07-03
    • Kiyoyuki NarimatsuHideo Nishibayashi
    • Kiyoyuki NarimatsuHideo Nishibayashi
    • A61B5/0225A61B5/021A61B5/02
    • A61B5/02225A61B5/02116A61B5/0225
    • An apparatus for detecting a pressure pulse wave from a living subject, including a pressure pulse wave sensor which detects a pressure pulse wave which is produced from an artery of the subject, a pressing device which presses the sensor against the artery via a body surface of the subject, a position changing device which moves the sensor and thereby changes a position of the sensor relative to the artery in a direction of width of the artery, and a control device which determines, based on the pulse wave detected by the sensor, an optimum pressing position of the sensor where the sensor is pressed against the artery by the pressing device, and controls the position changing device to position the sensor at the optimum pressing position, the control device functioning as a moving device for controlling the position changing device to move the sensor relative to the artery while the sensor is pressed on the body surface by the pressing device, a determining device for determining the optimum pressing position of the sensor based on the pressure pulse wave detected by the sensor while the sensor is pressed by the pressing device and is moved by the position changing device under control of the moving device, and a stopping device for controlling the position changing device to stop moving the sensor when the optimum pressing position of the sensor is determined by the determining device.
    • 一种用于检测来自活体的压力脉搏波的装置,包括检测从被检体的动脉产生的压力脉搏波的压力脉搏波传感器,将传感器经由身体表面压靠在动脉上的按压装置, 所述被摄体,位置改变装置,其移动所述传感器,从而在所述动脉的宽度方向上改变所述传感器相对于所述动脉的位置;以及控制装置,其基于由所述传感器检测到的脉搏波, 传感器通过按压装置压靠动脉的传感器的最佳按压位置,并且控制位置改变装置将传感器定位在最佳按压位置,该控制装置用作控制位置改变装置的移动装置 当所述传感器被所述按压装置按压在所述身体表面上时,相对于所述动脉移动所述传感器,确定装置 在传感器被按压装置按压的同时,基于由传感器检测到的压力脉搏波的传感器的最佳按压位置,并且在移动装置的控制下由位置改变装置移动,以及用于控制位置改变装置的停止装置 当确定装置确定传感器的最佳按压位置时,停止移动传感器。
    • 15. 发明授权
    • Arteriosclerosis evaluating apparatus
    • 动脉硬化评估仪
    • US06955649B2
    • 2005-10-18
    • US10194007
    • 2002-07-15
    • Kiyoyuki Narimatsu
    • Kiyoyuki Narimatsu
    • A61B5/02A61B5/021A61B5/022A61B5/0285
    • A61B5/6822A61B5/021A61B5/02116A61B5/02125A61B5/0285A61B5/7239A61B2562/0247A61B2562/043
    • An apparatus for evaluating arteriosclerosis of a living subject, including a blood-pressure measuring device which measures at least one blood-pressure value of the subject, a pulse-wave detecting device which detects a pulse wave from a portion of the subject, a relationship determining device for determining a relationship between pulse-wave magnitude and blood pressure, based on at least one magnitude of the pulse wave detected by the pulse-wave detecting device and said at least one blood-pressure value measured by the blood-pressure measuring device, an incident-wave-peak determining device for determining a magnitude of a peak point of an incident-wave component which is contained in the pulse wave detected by the pulse-wave detecting device, a reflected-wave-occurrence-time determining device for determining a time of occurrence of a peak point of a reflected-wave component which is contained in the pulse wave, a pressure-difference determining device for determining, according to the relationship between pulse-wave magnitude and blood pressure, a pressure difference corresponding to a magnitude difference between a magnitude of the pulse wave at the time of occurrence of the peak point of the reflected-wave component, and the magnitude of the peak point of the incident-wave component, and a display device which displays the pressure difference determined by the pressure-difference determining device.
    • 一种用于评估活体的动脉硬化的装置,包括测量被检体的至少一个血压值的血压测定装置,检测来自被检体的一部分的脉搏波的脉波检测装置, 确定装置,用于基于由脉搏波检测装置检测到的脉搏波的至少一个幅度和由血压测量装置测量的至少一个血压值,确定脉搏波幅度与血压之间的关系 ,用于确定包含在由脉波检测装置检测的脉搏波中的入射波分量的峰值的大小的入射波峰值确定装置,反射波发生时间确定装置, 确定包含在脉波中的反射波分量的峰值点的出现时间,根据 关于脉搏波幅度与血压之间的关系,与反射波分量的峰值点出现时的脉搏波的大小与峰值点的大小对应的压力差 的入射波分量的显示装置和显示由压力差判定装置确定的压力差的显示装置。
    • 17. 发明授权
    • Pressure-pulse-wave detecting apparatus
    • 压力脉波检测装置
    • US06802814B2
    • 2004-10-12
    • US10265399
    • 2002-10-07
    • Kiyoyuki Narimatsu
    • Kiyoyuki Narimatsu
    • A61B502
    • A61B5/02116A61B5/02225A61B5/6843
    • An apparatus for detecting a pressure pulse wave from a living subject, including a pressure-pulse-wave sensor which is adapted to be pressed against a portion of the subject to detect the pressure pulse wave from the subject, a pressing device which presses the pressure-pulse-wave sensor against the portion of the subject, a blood-pressure measuring device which measures at least one blood pressure value of the subject, and a comparison-value determining device for determining a comparison value based on the at least one blood pressure value measured by the blood-pressure measuring device and at least one pressure value corresponding to the pressure pulse wave detected by the pressure-pulse-wave sensor.
    • 一种用于检测来自活体的压力脉搏波的装置,包括压力脉搏波传感器,该压力脉波传感器适于被压靠在被检体的一部分上以检测来自被检体的压力脉搏波;压力装置, 脉冲波传感器抵靠对象的部分,测量受试者的至少一个血压值的血压测量装置,以及用于基于至少一个血压确定比较值的比较值确定装置 由血压测量装置测量的值和与压力脉搏波传感器检测到的压力脉搏波相对应的至少一个压力值。
    • 18. 发明授权
    • Arteriosclerosis evaluating apparatus
    • 动脉硬化评估仪
    • US06666827B2
    • 2003-12-23
    • US10193986
    • 2002-07-15
    • Kiyoyuki Narimatsu
    • Kiyoyuki Narimatsu
    • A61B502
    • A61B5/02007A61B5/02A61B5/0285
    • An apparatus for evaluating arteriosclerosis of a living subject, including a pulse-wave detecting device which detects a pulse wave from each of a first portion and a second portion of the subject, each of the respective pulse waves detected from the first and second portions containing an incident-wave component, an augmentation-index determining device for determining, based on the pulse wave detected from the first portion by the pulse-wave detecting device, a first augmentation index indicative of a degree of augmentation of an amplitude of the pulse wave detected from the first portion, from an amplitude of the incident-wave component of the pulse wave detected from the first portion, and determining, based on the pulse wave detected from the second portion by the pulse-wave detecting device, a second augmentation index indicative of a degree of augmentation of an amplitude of the pulse wave detected from the second portion, from an amplitude of the incident-wave component of the pulse wave detected from the second portion, and an arteriosclerosis evaluating device for evaluating the arteriosclerosis of the subject, based on a comparison of the first and second augmentation indexes determined by the augmentation-index determining device.
    • 一种用于评估活体的动脉硬化的装置,包括:检测来自被检体的第一部分和第二部分的脉波的脉波检测装置,从所述第一部分和第二部分检测出的各个脉搏波包含 入射波分量,增强指数确定装置,用于基于由所述脉搏波检测装置从所述第一部分检测到的脉搏波,确定指示所述脉波的幅度的增大程度的第一增强指数 从所述第一部分检测出的从所述第一部分检测到的所述脉波的入射波分量的振幅,并且基于由所述脉搏波检测装置从所述第二部分检测到的脉搏波,确定第二增强指数 指示从第二部分检测到的脉搏波的幅度的增加程度,从第二部分的入射波分量的振幅 基于由增加指数确定装置确定的第一和第二增强指数的比较,从第二部分检测的脉搏波和用于评估对象的动脉硬化的动脉硬化评估装置。
    • 19. 发明授权
    • Augmentation-index measuring apparatus
    • 增强指数测量仪
    • US06659958B2
    • 2003-12-09
    • US10352230
    • 2003-01-28
    • Kiyoyuki NarimatsuAkira Tampo
    • Kiyoyuki NarimatsuAkira Tampo
    • A61B500
    • A61B5/02007A61B5/02116A61B5/022A61B5/7239
    • An augmentation-index measuring apparatus including a cuff which is adapted to be worn on a portion of a living subject to press the portion, a fourth-order-differentiating device for subjecting a cuff pulse wave obtained from the cuff, to a fourth-order differentiation, and thereby obtaining a fourth-order-differentiated waveform, a peak-point determining device for determining, based on the fourth-order-differentiated waveform obtained by the fourth-order-differentiating device, a peak point of an incident-wave component contained in the cuff pulse wave and a peak point of a reflected-wave component contained in the cuff pulse wave, and an augmentation-index determining device for determining an augmentation index of the subject that indicates a proportion of one of a first magnitude of the cuff pulse wave at a time of occurrence of the peak point of the incident-wave component and a second magnitude of the cuff pulse wave at a time of occurrence of the peak point of the reflected-wave component, to the other of the first and second magnitudes.
    • 一种增强指数测量装置,包括适于佩戴在活体的一部分以按压该部分的袖带,用于使从袖带获得的袖带脉搏波的四阶微分装置为四阶 微分,从而获得四阶微分波形;峰值确定装置,用于基于由四阶微分装置获得的四阶微分波形确定入射波分量的峰值点 包含在袖带脉波中的包含在袖带脉波中的反射波分量的峰值点的增强指数确定装置,以及用于确定对象的增强指数的增强指数确定装置,该增强指数确定装置指示对象的第一大小 入射波分量的峰值点出现时的袖带脉波,以及反射波峰出现时袖带脉波的第二幅度 ve分量,到第一和第二大小的另一个。
    • 20. 发明授权
    • Blood-pressure monitoring apparatus
    • 血压监测仪
    • US06186954B1
    • 2001-02-13
    • US09397637
    • 1999-09-16
    • Kiyoyuki Narimatsu
    • Kiyoyuki Narimatsu
    • A61B500
    • A61B5/022A61B5/0285A61B5/0402
    • A blood-pressure monitoring apparatus including a measuring device which includes an inflatable cuff adapted to apply a pressing pressure to a body portion of a living subject and measures a blood-pressure value of the living subject by changing the pressing pressure of the inflatable cuff, an information obtaining device which iteratively obtains a piece of information relating to propagation of a pulse wave through an arterial vessel of the subject, an estimating device for iteratively estimating a blood-pressure value, EBP, of the subject, based on each piece of pulse-wave-propagation-relating information, PWPI, obtained by the information obtaining device, according to a linear relationship between pulse-wave-propagation-relating information and blood pressure, the linear relationship being defined by a linear expression, EBP=&agr;(PWPI)+&agr;, where &agr; is a slope and &bgr; is an intercept, an index-value calculating device for calculating an index value indicative of a hardness of a blood vessel of the subject, and a slope determining device for determining, based on the calculated index value, the slope &agr; of the linear expression.
    • 一种血压监视装置,包括:测量装置,其包括适于对生物体的身体部位施加按压压力的充气套,并且通过改变所述可充气袖带的按压压力来测量所述生物体的血压值; 信息获取装置,其迭代地获得与通过对象的动脉血管的脉搏波的传播有关的信息,用于基于每个脉冲迭代地估计被检体的血压值EBP的估计装置 由信息获取装置获得的波传播相关信息PWPI根据脉搏波传播相关信息与血压之间的线性关系,线性关系由线性表达式定义,EBP =α(PWPI )+α,其中α是斜率,β是截距,用于计算指示硬度的指标值的指标值计算装置 以及用于根据计算出的指标值确定线性表达式的斜率α的斜率确定装置。