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11. 发明申请

US20130331761A1 Methods and Apparatus for Treating Glaucoma 有权
公开(公告)号：US20130331761A1
公开(公告)日：2013-12-12
申请号：US13968051
申请日：2013-08-15
申请人： Charles L. Euteneuer , Thomas R. Hektner , Andrew T. Schieber , John Wardle
发明人： Charles L. Euteneuer , Thomas R. Hektner , Andrew T. Schieber , John Wardle
IPC分类号： A61F9/007
CPC分类号： A61F9/00781 , A61F9/0017 , A61F9/007 , A61F2009/00885 , A61F2009/00891 , A61K9/0051 , A61M27/002 , A61M2210/0612 , Y10S623/905 , Y10S623/906
摘要： An ocular implant for treating glaucoma is provided, which may include any number of features. More particularly, the present invention relates to implants that facilitate the transfer of fluid from within one area of the eye to another area of the eye. One feature of the implant is that it includes a proximal inlet portion and a distal inlet portion adapted to be inserted into the anterior chamber of the eye, and an intermediate portion adapted to be inserted into Schlemm's canal. Another feature of the implant is that it can be biased to assume a predetermined shape to aid in placement within the eye.

12. 发明申请

US20090227934A1 Methods and Apparatus for Treating Glaucoma 有权
标题翻译：治疗青光眼的方法和装置
公开(公告)号：US20090227934A1
公开(公告)日：2009-09-10
申请号：US12398847
申请日：2009-03-05
申请人： Charles L. Euteneuer , Thomas R. Hektner , Andrew T. Schieber , John Wardle
发明人： Charles L. Euteneuer , Thomas R. Hektner , Andrew T. Schieber , John Wardle
IPC分类号： A61F9/007 , A61B17/32
CPC分类号： A61F9/00781 , A61F9/0017 , A61F9/007 , A61F2009/00885 , A61F2009/00891 , A61K9/0051 , A61M27/002 , A61M2210/0612 , Y10S623/905 , Y10S623/906
摘要： An ocular implant for treating glaucoma is provided, which may include any number of features. More particularly, the present invention relates to implants that facilitate the transfer of fluid from within one area of the eye to another area of the eye. One feature of the implant is that it includes a proximal inlet portion and a distal inlet portion adapted to be inserted into the anterior chamber of the eye, and an intermediate portion adapted to be inserted into Schlemm's canal. Another feature of the implant is that it can be biased to assume a predetermined shape to aid in placement within the eye.
摘要翻译：提供了用于治疗青光眼的眼部植入物，其可以包括任何数量的特征。更具体地说，本发明涉及有利于将流体从眼睛的一个区域转移到眼睛的另一区域的植入物。植入物的一个特点是它包括适于插入眼睛前房的近端入口部分和远侧入口部分，以及适于插入施莱姆氏管的中间部分。植入物的另一个特征是它可被偏置以呈现预定的形状以帮助放置在眼睛内。

13. 发明申请

US20100222733A1 Glaucoma Treatment Method 有权
标题翻译：青光眼治疗方法
公开(公告)号：US20100222733A1
公开(公告)日：2010-09-02
申请号：US12775266
申请日：2010-05-06
申请人： Andrew T. Schieber , Charles L. Euteneuer
发明人： Andrew T. Schieber , Charles L. Euteneuer
IPC分类号： A61M1/00 , A61F2/14
CPC分类号： A61F9/00781 , A61F9/0017 , A61F2009/00891 , A61M27/002 , A61M2210/0612
摘要： An ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye. In some embodiments the implant has a body extending in a curved volume whose longitudinal axis forms an arc of a circle, and a plurality of open areas and strut areas formed in the body, the open areas extending over more than 50% of a surface defining the curved volume, the strut areas surrounding the open areas, the body having a diameter of between 0.005 inches and 0.04 inches. The invention also provides a method of treating glaucoma including the steps of supporting tissue forming Schlemm's canal in an eye with an implant extending at least partially in the canal along an axial length within the canal; and contacting with the implant less than 50% of the tissue forming the canal along the axial length.
摘要翻译：适于至少部分地居住在眼睛的施莱姆氏管的一部分中的眼部植入物。在一些实施例中，植入物具有在弯曲体积中延伸的主体，其纵向轴线形成圆弧，以及形成在主体中的多个开放区域和支柱区域，所述开放区域延伸超过表面的50％以上弯曲的体积，围绕开放区域的支柱区域，主体具有在0.005英寸和0.04英寸之间的直径。本发明还提供一种治疗青光眼的方法，包括以下步骤：在眼睛中支撑组织形成施莱姆氏管，其中植入物至少部分地沿着管内的轴向长度延伸至管内; 并且沿着轴向长度与植入物接触形成管的少于50％的组织。

14. 发明申请

US20090082860A1 Ocular Implants with Asymmetric Flexibility 有权
标题翻译：具有不对称柔性的眼植入物
公开(公告)号：US20090082860A1
公开(公告)日：2009-03-26
申请号：US12236225
申请日：2008-09-23
申请人： Andrew T. Schieber , Charles L. Euteneuer
发明人： Andrew T. Schieber , Charles L. Euteneuer
IPC分类号： A61F2/14 , A61K9/00 , A61P27/02
CPC分类号： A61F9/00781 , A61F2/14 , A61F2/15 , A61F2220/0008 , A61F2250/0067
摘要： An ocular implant having a body extending along a generally curved longitudinal axis, the curved longitudinal axis defining a first plane, the body having a diameter of between 0.005 inches and 0.04 inches and being adapted to be disposed within a canal of Schlemm in a human subject's eye; wherein the body has a first flexibility when bent along the first plane and a second flexibility different from the first flexibility when bent along a second plane that intersects the first plane and is not coincident with the first plane. Another aspect of the invention provides a method of treating a human eye, including the steps of: inserting an implant into Schlemm's canal of a human eye, the implant having a first flexibility when bent along a first plane and a second flexibility different from the first flexibility when bent along a second plane that intersects the first plane and is not coincident with the first plane; and supporting tissue forming Schlemm's canal with the implant.
摘要翻译：一种眼部植入物，其具有沿着大致弯曲的纵向轴线延伸的主体，所述弯曲纵向轴线限定第一平面，所述主体具有在0.005英寸和0.04英寸之间的直径，并且适于设置在人类受试者的Schlemm的管道内眼; 其中当沿着与所述第一平面相交并且与所述第一平面不一致的第二平面弯曲时，所述主体沿着所述第一平面弯曲时具有第一柔性，并且所述第二柔性不同于所述第一柔性。本发明的另一方面提供了一种治疗人眼的方法，包括以下步骤：将植入物插入人眼的施莱姆氏管中，所述植入物沿着第一平面弯曲时具有第一柔性，并且具有与第一平面不同的第二柔性当沿着与第一平面相交并且不与第一平面重合的第二平面弯曲时的柔性; 并用植入物支撑组织形成Schlemm的运河。

15. 发明申请

US20130150959A1 Ocular Implant Architectures 有权
公开(公告)号：US20130150959A1
公开(公告)日：2013-06-13
申请号：US13763394
申请日：2013-02-08
申请人： Andrew T. Schieber , Charles L. Euteneuer
发明人： Andrew T. Schieber , Charles L. Euteneuer
IPC分类号： A61F2/14
CPC分类号： A61M5/00 , A61F2/14 , A61F9/00781 , A61F2250/0067
摘要： An ocular implant having a first spine; a second spine; a first strut extending in an axial direction Z between the first spine and the second spine; a second strut extending in an axial direction Z between the first spine and the second spine; wherein an angular dimension θ of a first edge of each strut undulates as the strut extends in the axial direction Z between the first spine and the second spine; and wherein a radius r of an outer surface of each strut remains substantially constant as the strut extends the axial direction Z between the first spine and the second spine.

16. 发明授权

US08282592B2 Glaucoma treatment method 有权
标题翻译：青光眼治疗方法
公开(公告)号：US08282592B2
公开(公告)日：2012-10-09
申请号：US12775266
申请日：2010-05-06
申请人： Andrew T. Schieber , Charles L. Euteneuer
发明人： Andrew T. Schieber , Charles L. Euteneuer
IPC分类号： A61M5/00 , A61F2/00 , A61F2/14
CPC分类号： A61F9/00781 , A61F9/0017 , A61F2009/00891 , A61M27/002 , A61M2210/0612
摘要： An ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye. In some embodiments the implant has a body extending in a curved volume whose longitudinal axis forms an arc of a circle, and a plurality of open areas and strut areas formed in the body, the open areas extending over more than 50% of a surface defining the curved volume, the strut areas surrounding the open areas, the body having a diameter of between 0.005 inches and 0.04 inches. The invention also provides a method of treating glaucoma including the steps of supporting tissue forming Schlemm's canal in an eye with an implant extending at least partially in the canal along an axial length within the canal; and contacting with the implant less than 50% of the tissue forming the canal along the axial length.
摘要翻译：适于至少部分地居住在眼睛的施莱姆氏管的一部分中的眼部植入物。在一些实施例中，植入物具有在弯曲体积中延伸的主体，其纵向轴线形成圆弧，以及形成在主体中的多个开放区域和支柱区域，所述开放区域延伸超过表面的50％以上弯曲的体积，围绕开放区域的支柱区域，主体具有在0.005英寸和0.04英寸之间的直径。本发明还提供一种治疗青光眼的方法，包括以下步骤：在眼睛中支撑组织形成施莱姆氏管，其中植入物至少部分地沿着管内的轴向长度延伸至管内; 并且沿着轴向长度与植入物接触形成管的少于50％的组织。

17. 发明申请

US20090082862A1 Ocular Implant Architectures 审中-公开
标题翻译：眼植入物架构
公开(公告)号：US20090082862A1
公开(公告)日：2009-03-26
申请号：US12236254
申请日：2008-09-23
申请人： Andrew T. Schieber , Charles L. Euteneuer
发明人： Andrew T. Schieber , Charles L. Euteneuer
IPC分类号： A61F2/16
CPC分类号： A61M5/00 , A61F2/14 , A61F9/00781 , A61F2250/0067
摘要： An ocular implant having a first spine; a second spine; a first strut extending in an axial direction Z between the first spine and the second spine; a second strut extending in an axial direction Z between the first spine and the second spine; wherein an angular dimension θ of a first edge of each strut undulates as the strut extends in the axial direction Z between the first spine and the second spine; and wherein a radius r of an outer surface of each strut remains substantially constant as the strut extends the axial direction Z between the first spine and the second spine.
摘要翻译：一种具有第一脊柱的眼部植入物; 第二脊柱在所述第一脊柱和所述第二脊骨之间沿轴向方向Z延伸的第一支柱; 在所述第一脊柱和所述第二脊骨之间沿轴向方向Z延伸的第二支柱; 其中每个支柱的第一边缘的角度尺寸θ随着支柱在第一脊柱和第二脊柱之间的轴向方向Z上延伸而波动; 并且其中每个支柱的外表面的半径r保持基本上恒定，因为支柱延伸第一脊柱和第二脊柱之间的轴向方向Z。

18. 发明授权

US08372026B2 Ocular implant architectures 有权
标题翻译：眼植入物架构
公开(公告)号：US08372026B2
公开(公告)日：2013-02-12
申请号：US13366073
申请日：2012-02-03
申请人： Andrew T. Schieber , Charles L. Euteneuer
发明人： Andrew T. Schieber , Charles L. Euteneuer
IPC分类号： A61M5/00
CPC分类号： A61M5/00 , A61F2/14 , A61F9/00781 , A61F2250/0067
摘要： An ocular implant having a first spine; a second spine; a first strut extending in an axial direction Z between the first spine and the second spine; a second strut extending in an axial direction Z between the first spine and the second spine; wherein an angular dimension θ of a first edge of each strut undulates as the strut extends in the axial direction Z between the first spine and the second spine; and wherein a radius r of an outer surface of each strut remains substantially constant as the strut extends the axial direction Z between the first spine and the second spine.
摘要翻译：一种具有第一脊柱的眼部植入物; 第二脊柱在所述第一脊柱和所述第二脊骨之间沿轴向方向Z延伸的第一支柱; 在所述第一脊柱和所述第二脊骨之间沿轴向方向Z延伸的第二支柱; 其中角度尺寸＆amp; 每个支柱的第一边缘随着支柱沿第一脊柱和第二脊柱之间的轴向方向Z延伸而波动; 并且其中每个支柱的外表面的半径r保持基本上恒定，因为支柱延伸第一脊柱和第二脊柱之间的轴向方向Z。

19. 发明授权

US08734377B2 Ocular implants with asymmetric flexibility 有权
标题翻译：具有不对称柔性的眼植入物
公开(公告)号：US08734377B2
公开(公告)日：2014-05-27
申请号：US12236225
申请日：2008-09-23
申请人： Andrew T. Schieber , Charles L. Euteneuer
发明人： Andrew T. Schieber , Charles L. Euteneuer
IPC分类号： A61M5/00 , A61F2/14
CPC分类号： A61F9/00781 , A61F2/14 , A61F2/15 , A61F2220/0008 , A61F2250/0067
摘要： An ocular implant having a body extending along a generally curved longitudinal axis, the curved longitudinal axis defining a first plane, the body having a diameter of between 0.005 inches and 0.04 inches and being adapted to be disposed within a canal of Schlemm in a human subject's eye; wherein the body has a first flexibility when bent along the first plane and a second flexibility different from the first flexibility when bent along a second plane that intersects the first plane and is not coincident with the first plane. Another aspect of the invention provides a method of treating a human eye, including the steps of: inserting an implant into Schlemm's canal of a human eye, the implant having a first flexibility when bent along a first plane and a second flexibility different from the first flexibility when bent along a second plane that intersects the first plane and is not coincident with the first plane; and supporting tissue forming Schlemm's canal with the implant.
摘要翻译：一种眼部植入物，其具有沿着大致弯曲的纵向轴线延伸的主体，所述弯曲纵向轴线限定第一平面，所述主体具有在0.005英寸和0.04英寸之间的直径，并且适于设置在人类受试者的Schlemm的管道内眼; 其中当沿着与所述第一平面相交并且与所述第一平面不一致的第二平面弯曲时，所述主体沿着所述第一平面弯曲时具有第一柔性，并且所述第二柔性不同于所述第一柔性。本发明的另一方面提供了一种治疗人眼的方法，包括以下步骤：将植入物插入人眼的施莱姆氏管中，所述植入物沿着第一平面弯曲时具有第一柔性，并且具有与第一平面不同的第二柔性当沿着与第一平面相交并且不与第一平面重合的第二平面弯曲时的柔性; 并用植入物支撑组织形成Schlemm的运河。

20. 发明授权

US07740604B2 Ocular implants for placement in schlemm's canal 有权
标题翻译：用于放置在施莱姆运河中的眼部植入物
公开(公告)号：US07740604B2
公开(公告)日：2010-06-22
申请号：US11860318
申请日：2007-09-24
申请人： Andrew T. Schieber , Charles L. Euteneuer
发明人： Andrew T. Schieber , Charles L. Euteneuer
IPC分类号： A61M27/00
CPC分类号： A61F9/00781 , A61F9/0017 , A61F2009/00891 , A61M27/002 , A61M2210/0612
摘要： An ocular implant adapted to reside at least partially in a portion of Schlemm's canal of an eye. In some embodiments the implant has a body extending in a curved volume whose longitudinal axis forms an arc of a circle, and a plurality of open areas and strut areas formed in the body, the open areas extending over more than 50% of a surface defining the curved volume, the strut areas surrounding the open areas, the body having a diameter of between 0.005 inches and 0.04 inches. The invention also provides a method of treating glaucoma including the steps of supporting tissue forming Schlemm's canal in an eye with an implant extending at least partially in the canal along an axial length within the canal; and contacting with the implant less than 50% of the tissue forming the canal along the axial length.
摘要翻译：适于至少部分地居住在眼睛的施莱姆氏管的一部分中的眼部植入物。在一些实施例中，植入物具有在弯曲体积中延伸的主体，其纵向轴线形成圆弧，以及形成在主体中的多个开放区域和支柱区域，所述开放区域延伸超过表面的50％以上弯曲的体积，围绕开放区域的支柱区域，主体具有在0.005英寸和0.04英寸之间的直径。本发明还提供一种治疗青光眼的方法，包括以下步骤：在眼睛中支撑组织形成施莱姆氏管，其中植入物至少部分地沿着管内的轴向长度延伸至管内; 并且沿着轴向长度与植入物接触形成管的少于50％的组织。

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