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11. 发明申请

US20100211130A1 Treatment of the Autonomic Nervous System 有权
标题翻译：治疗自主神经系统
公开(公告)号：US20100211130A1
公开(公告)日：2010-08-19
申请号：US12706608
申请日：2010-02-16
申请人： Valerio Cigaina
发明人： Valerio Cigaina
IPC分类号： A61N1/00
CPC分类号： A61N1/36139 , A61B5/02405 , A61B5/0456 , A61B5/4035 , A61N1/36085
摘要： Systems and methods are provided for modulating the autonomic nervous system by the electrical stimulation of the neuro-muscular system of a patient, and include an implantable electrical system for gastrointestinal stimulation which incorporates a heart rate sensor to indicate the neurovegetative patient condition, to initiate and terminate stimulation at specific locations, and an algorithm to automatically control electrical stimulation frequency, interval, amplitude, or a combination of such parameters for adaptive treatment of obesity, anorexia, other eating disorders, diseases related with the so called “metabolic syndrome” (e.g., impaired glucose tolerance and diabetes type 2, GERD, systemic hypertension, early arterovascular degeneration, early senility, and the like), and disorders related to a pathologic inbalance of the autonomic nervous system.
摘要翻译：提供了系统和方法，用于通过对患者的神经 - 肌肉系统的电刺激来调节自主神经系统，并且包括用于胃肠刺激的可植入电气系统，其包括心率传感器以指示神经递质患者状况，以启动和在特定位置终止刺激，以及自动控制电刺激频率，间隔，幅度或这些参数的组合的算法，用于适应性治疗肥胖症，厌食症，其他进食障碍，与所谓的“代谢综合征”相关的疾病（例如，，糖耐量异常和2型糖尿病，GERD，全身高血压，早期动脉血管变性，早衰等），以及与自主神经系统的病理性失衡相关的疾病。

12. 发明授权

US06321124B1 Implant device for electrostimulation and/or monitoring of endo-abdominal cavity tissue 有权
标题翻译：用于电刺激和/或监测腹腔内组织的植入装置
公开(公告)号：US06321124B1
公开(公告)日：2001-11-20
申请号：US09424324
申请日：2000-01-26
申请人： Valerio Cigaina
发明人： Valerio Cigaina
IPC分类号： A61N105
CPC分类号： A61N1/05
摘要： An implant device specifically for electrostimulation and/or electrical monitoring of endo-abdominal tissue or viscera is provided. The implant device has an elongated body equipped with devices to secure it to the tissue to be treated and two or more electric poles that are electrically connected to an electric connection terminal for connection to a power source to penetrate the tissue to be treated, and quick-release connecting devices to separate the penetration device from the elongated body.
摘要翻译：提供专门用于电刺激和/或电监测内腹组织或内脏的植入装置。植入装置具有细长体，其配备有将其固定到待治疗组织的装置和电连接到电连接端子的两个或多个电极，用于连接到电源以穿透待治疗的组织，并且快速 - 释放连接装置以将穿透装置与细长体分开。

13. 发明授权

US5423872A Process and device for treating obesity and syndromes related to motor disorders of the stomach of a patient 失效
标题翻译：用于治疗与患者胃运动障碍有关的肥胖症和综合征的方法和装置
公开(公告)号：US5423872A
公开(公告)日：1995-06-13
申请号：US67390
申请日：1993-05-26
申请人： Valerio Cigaina
发明人： Valerio Cigaina
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/36007
摘要： The process for treating obesity and syndromes related to motor disorders of the stomach of a patient consists in artificially altering, by means of sequential electrical pulses and for preset periods of time, the natural gastric motility of the patient to prevent emptying or to slow down gastric transit.
摘要翻译：用于治疗与患者胃运动障碍有关的肥胖症和综合征的过程包括通过连续的电脉冲和预设的时间段人为地改变患者的天然胃动力以防止排空或减缓胃过境

14. 发明授权

US10441799B2 Set comprising a totally implantable device for electroneuromodulation and an implantation tool of said device 有权
公开(公告)号：US10441799B2
公开(公告)日：2019-10-15
申请号：US15038767
申请日：2014-11-28
申请人： Valerio Cigaina
发明人： Valerio Cigaina , Paolo Fabris , Simone Cigaina
IPC分类号： A61B17/34 , A61N1/372 , A61N1/375 , A61N1/05 , A61N1/36 , A61N1/378 , A61B17/00
摘要： The set comprises a totally implantable device (1) for electroneuromodulation for the electric stimulation of the nervous tissue of the wall of the stomach and/or another neuroreceptive biological tissue and an implantation tool (2) of the device (1), the tool (2) comprising an axially hollow longitudinal containment body (6) for said device (1) and a needle (12) incorporated into said containment body (6) and having a tip (13) that projects forwards to a sharp front end (7) of the containment body (6), said needle (12) being connected to a supply conduit (15) of a fluid injectable from said needle (12) into the tissue for the creation of a localized tissue swelling (4) in which said device (1) can be positioned.

15. 发明授权

US06908487B2 Anti-gastroesophageal reflux valvular prosthesis 失效
标题翻译：抗胃食管反流瓣膜假体
公开(公告)号：US06908487B2
公开(公告)日：2005-06-21
申请号：US10259263
申请日：2002-09-27
申请人： Valerio Cigaina
发明人： Valerio Cigaina
IPC分类号： A61F2/04
CPC分类号： A61F2/04
摘要： The anti-gastroesophageal reflux valvular prosthesis has a body presenting a seat of substantially semicircular shape engageable with the gastric wall of the stomach connected to the body through connectors and inflatable for the variation of this volume to accentuate the angle of His (cardiac incisure) and to improve the natural valvular anti-reflux system.
摘要翻译：抗胃食管反流瓣膜假体具有呈现基本上半圆形形状的座体的主体，其与通过连接器连接到身体的胃的胃壁相接合，并且可充气以改变该体积以增强His（心脏不适）的角度和改善天然瓣膜反流系统。

16. 发明授权

US06889076B2 Device and procedure for controlling the extent of intra-abdominal fat in the monitoring of an individual's slimming 失效
标题翻译：用于控制腹内脂肪在监测个体减肥的程度
公开(公告)号：US06889076B2
公开(公告)日：2005-05-03
申请号：US10112600
申请日：2002-03-28
申请人： Valerio Cigaina
发明人： Valerio Cigaina
IPC分类号： A61B5/053 , A61B5/00
CPC分类号： A61B5/4872 , A61B5/0537 , A61B5/0538 , A61B5/4238
摘要： The device (1) for controlling the extent of intra-abdominal fat in the monitoring of an individual's slimming, comprises one electrical signal generator (2) connected to at least one first pole (3), associable to the stomach surface, and a second pole (4), associable to the abdominal wall. The poles (3,4) are connected to detection means (6) and means (7) for processing said electrical signals, adapted to provide a signal indicating the extent of intra-abdominal fat. The control procedure of the entity of the intra-abdominal fat in the monitoring of an individual's slimming, consists in detecting the impedance of the abdominal fat tissues, and hence, in calculating the extent of intra-abdominal fat is obtained.
摘要翻译：用于控制个体减肥监测中腹内脂肪的程度的装置（1）包括连接到与胃表面相关联的至少一个第一极（3）的一个电信号发生器（2）杆（4），与腹壁相关。极（3,4）连接到检测装置（6）和用于处理所述电信号的装置（7），适于提供指示腹内脂肪的程度的信号。监测个体减肥的腹内脂肪实体的控制程序包括检测腹部脂肪组织的阻抗，因此在计算腹腔内脂肪的程度时得到。

17. 发明授权

US6041258A Medical stimulation 失效
标题翻译：医疗刺激和监测装置，具有快速释放机构和可拆卸手柄，用于植入体腔
公开(公告)号：US6041258A
公开(公告)日：2000-03-21
申请号：US122832
申请日：1998-07-27
申请人： Valerio Cigaina , David Jenkins
发明人： Valerio Cigaina , David Jenkins
IPC分类号： A61N1/05 , A61N1/36
CPC分类号： A61N1/05
摘要： An improved handle for a medical device used in laparoscopic surgery is provided. This handle is especially adapted for use with an implant device specifically for electrostimulation and/or electrical monitoring of endo-abdominal tissue or viscera is provided. The implant device has an elongated body equipped with devices to secure it to the tissue to be treated and two or more electric poles that are electrically connected to an electric connection terminal for connection to a power source, means to penetrate the tissue to be treated, and quick-release connecting devices to separate the penetration device from the elongated body. The handle, which is an elongated body, is attached to the proximal end of the implant device or other medical device and has a grasping means at its opposite end for manipulation with laparoscopic forceps.
摘要翻译：提供了用于腹腔镜手术中的医疗装置的改进的手柄。该手柄特别适用于专门用于电刺激和/或内部腹部组织或内脏的电监测的植入装置。植入装置具有细长体，其配备有将其固定到要处理的组织的装置，以及电连接到用于连接到电源的电连接端子的两个或更多个电极，穿透待治疗组织的装置，和快速释放连接装置以将穿透装置与细长体分开。作为细长主体的手柄附接到植入装置或其他医疗装置的近端，并且在其相对端具有抓握装置，以用腹腔镜钳进行操作。

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