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11. 发明申请

US20100320096A1 BIOMOLECULES DETECTION METHOD AND BIOMOLECULES DETECTION CHIP 审中-公开
标题翻译：生物分子检测方法和生物分子检测芯片
公开(公告)号：US20100320096A1
公开(公告)日：2010-12-23
申请号：US12449373
申请日：2008-02-05
申请人： Masato Nakayama
发明人： Masato Nakayama
IPC分类号： G01N27/26 , G01N27/416
CPC分类号： G01N27/3277 , B01L3/502715 , B01L7/52 , C12Q1/6825 , C12Q2537/101 , C12Q2563/113 , C12Q2565/607
摘要： A biomolecules detection method which detects a detection target biomolecule by a measurement of an electrochemical response, the method including: a standard solution measurement process which measures an electrochemical response of a standard solution which includes an electrochemically reactive agent having a direct or indirect binding capacity to the detection target biomolecule; sample solution measurement process which measures the electrochemical response of a sample solution, the sample solution containing, a sample material containing the detection target biomolecule, and the electrochemically reactive agent; a comparison process which compares an electrochemical response measurement result of the standard solution and an electrochemical response measurement result of the sample solution, and thereby obtains a comparison result; and a biomolecules content information detection process which, based on the comparison result, detects a content information of the detection target biomolecule in the sample solution.
摘要翻译：一种生物分子检测方法，其通过测量电化学响应来检测检测目标生物分子，所述方法包括：标准溶液测量方法，其测量标准溶液的电化学响应，其包括具有直接或间接结合能力的电化学反应剂检测目标生物分子; 样品溶液测量过程，其测量样品溶液的电化学响应，样品溶液含有含有检测目标生物分子的样品材料和电化学反应剂; 比较标准溶液的电化学响应测量结果和样品溶液的电化学响应测量结果的比较过程，从而获得比较结果; 以及基于比较结果的检测目标生物分子的内容信息的生物分子内容信息检测处理。

12. 发明申请

US20060223811A1 Triglycerine depressant composition 审中-公开
标题翻译：甘油三酯抑制剂组合物
公开(公告)号：US20060223811A1
公开(公告)日：2006-10-05
申请号：US11447735
申请日：2006-06-06
申请人： Tsuneki Ohsawa , Ikuo Takagi , Ippei Shimizu , Tatsuhito Kondo , Masato Nakayama , Yasuhiro Torizumi
发明人： Tsuneki Ohsawa , Ikuo Takagi , Ippei Shimizu , Tatsuhito Kondo , Masato Nakayama , Yasuhiro Torizumi
IPC分类号： A61K31/525 , A61K31/444 , A61K31/366 , A61K31/375 , A61K31/22 , A61K31/198
CPC分类号： A61K31/16 , A61K31/22 , A61K31/225 , A61K31/355 , A61K31/366 , A61K31/375 , A61K31/444 , A61K31/455 , A61K31/498 , A61K31/519 , A61K31/525 , A61K2300/00
摘要： A blood triglyceride depressant composition which comprises pravastatin and one or more members selected from the group consisting of (1) pantethine, (2) inositol hexanicotinate, (3) a combination drug containing a riboflavin compound, a tocopherol compound and an ascorbic acid compound, and (4) a combination drug containing a tocopherol compound and an ascorbic acid compound.
摘要翻译：一种血甘油三酯抑制剂组合物，其包含普伐他汀和一种或多种选自（1）潘尼泰，（2）肌醇六氰酸酯，（3）含有核黄素化合物，生育酚化合物和抗坏血酸化合物的组合药物，和（4）含有生育酚化合物和抗坏血酸化合物的组合药物。

13. 发明申请

US20060140334A1 X-ray ct device an image selection method thereof 有权
标题翻译： X射线ct装置的图像选择方法
公开(公告)号：US20060140334A1
公开(公告)日：2006-06-29
申请号：US10544564
申请日：2004-02-12
申请人： Hideki Imaizumi , Masato Nakayama
发明人： Hideki Imaizumi , Masato Nakayama
IPC分类号： H05G1/60 , A61B6/00 , G01N23/00 , G21K1/12
CPC分类号： A61B6/032
摘要： An X-ray CT apparatus comprises an X-ray generation device which generates X-rays, an X-ray detector which detects the X-rays having passed through a subject and outputs projection data, an imaging control device which controls the X-ray generation device and the X-ray detector so as to collect projection data, an image reconstruction device which reconstructs image data from the projection data, an image display device which displays an image on the basis of the image data, an image selection information addition device which adds, to the image data, the image selection information for the image data, an image selection device which judges presence/absence of an image analysis process on the basis of the image selection information and selects the image data, and an image analysis processing device which performs the image analysis process on the basis of the image data-selected by the image selection device.
摘要翻译： X射线CT装置包括产生X射线的X射线产生装置，检测穿过被摄体的X射线并输出投影数据的X射线检测器，控制X射线的成像控制装置生成装置和X射线检测器，以便收集投影数据，从投影数据重建图像数据的图像重建装置，基于图像数据显示图像的图像显示装置，图像选择信息添加装置其对图像数据添加图像数据的图像选择信息，基于图像选择信息判断图像分析处理的有无的图像选择装置，并选择图像数据，以及图像分析处理装置，其基于由图像选择装置选择的图像数据执行图像分析处理。

14. 发明申请

US20050182036A1 Medicinal composition containing an HMG-CoA reductase inhibitor 审中-公开
标题翻译：含有HMG-CoA还原酶抑制剂的药物组合物
公开(公告)号：US20050182036A1
公开(公告)日：2005-08-18
申请号：US11045400
申请日：2005-01-27
申请人： Tatsuhito Kondo , Ikuo Takagi , Masato Nakayama , Yasuhiro Torizumi
发明人： Tatsuhito Kondo , Ikuo Takagi , Masato Nakayama , Yasuhiro Torizumi
IPC分类号： A61K9/00 , A61K9/16 , A61K9/20 , A61K31/225 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/401 , A61K31/51 , A61K31/56 , A61K31/575 , A61K45/06
CPC分类号： A61K9/2009 , A61K9/0095 , A61K9/1611 , A61K9/1623 , A61K31/225 , A61K31/365 , A61K31/366 , A61K31/40 , A61K31/401 , A61K31/51 , A61K31/56 , A61K31/575 , A61K45/06 , A61K2300/00
摘要： A pharmaceutical composition for promoting the synthesis of vascular endothelial nitrogen oxide and/or maintaining or elevating the concentration of vascular endothelial nitrogen oxide in the blood, or a pharmaceutical composition for improving blood lipids. The pharmaceutical composition contains an HMG-CoA reductase inhibitor; and gamma-oryzanol, and/or thiamines. For treatment, the components of the composition can be administered together, as a composition, or separately.
摘要翻译：用于促进血管内皮氮氧化物的合成和/或维持或提高血液中血管内皮氮氧化物浓度的药物组合物或用于改善血脂的药物组合物。药物组合物含有HMG-CoA还原酶抑制剂; 和γ-谷维素，和/或thiamines。对于治疗，组合物的组分可以一起施用，作为组合物或分开施用。

15. 发明申请

US20120105014A1 FULL CHARGE CAPACITY VALUE CORRECTION CIRCUIT, BATTERY PACK, AND CHARGING SYSTEM 有权
标题翻译：完全充电能力值校正电路，电池组和充电系统
公开(公告)号：US20120105014A1
公开(公告)日：2012-05-03
申请号：US13381580
申请日：2011-02-28
申请人： Masato Nakayama , Toshiyuki Nakatsuji , Hisashi Kameyama
发明人： Masato Nakayama , Toshiyuki Nakatsuji , Hisashi Kameyama
IPC分类号： G01R31/36 , H02J7/00
CPC分类号： G01R31/3624 , G01R31/3651
摘要： A full charge capacity value correction circuit, has: a current detection portion which detects a current value of current flowing in a secondary battery; a voltage detection portion which detects a terminal voltage value of the secondary battery; a capacity storage portion which stores a full charge capacity value indicating a full charge capacity of the secondary battery; a remaining quantity calculation portion which calculates, as a accumulated remaining quantity, a remaining charging quantity in the secondary battery from a total value obtained by cumulatively adding charged electrical quantities and subtracting discharged electrical quantities in the secondary battery, based on charge/discharge currents of the secondary battery detected by the current detection portion; a remaining quantity estimation portion which estimates, as an estimated remaining quantity, a remaining quantity of the secondary battery by using a terminal voltage value detected by the voltage detection portion; and a full charge capacity value correction portion which, when an estimated remaining quantity estimated by the remaining quantity estimation portion becomes equal to a reference value set in advance, in a case where the estimated remaining quantity is greater than the accumulated remaining quantity, adds a difference electrical quantity, which is equivalent to a difference between the thus estimated remaining quantity and accumulated remaining quantity calculated by the remaining quantity calculation portion, to the full charge capacity value stored in the capacity storage portion, but in a case where the estimated remaining quantity is less than the accumulated remaining quantity, subtracts the difference electrical quantity from the full charge capacity value stored in the capacity storage portion.
摘要翻译：一种完全充电容量值校正电路，具有：检测在二次电池中流动的电流的电流值的电流检测部; 电压检测部，其检测二次电池的端子电压值; 容量存储部，其存储表示二次电池的满充电容量的完全充电容量值; 剩余量计算部分，根据累积剩余量计算二次电池中的剩余充电量，该累计剩余量是根据累加电荷量累计增加并减去二次电池中的放电电量，所述二次电池由所述电流检测部检测; 剩余量估计部，通过使用由电压检测部检测出的端子电压值，作为估计剩余量，估计二次电池的剩余量; 以及完全充电容量值校正部，当所述估计剩余量大于所述累计剩余量的情况下，当由所述剩余量估计部估计的估计剩余量变得等于预先设定的基准值时，差分电量等于由剩余量计算部分计算出的这样估计的剩余量与累计剩余量之间的差与存储在容量存储部中的完全充电容量值的差，但是在估计剩余量小于累积剩余量，从存储在容量存储部中的满充电量值减去差电量。

16. 发明申请

US20100247807A1 ELECTRON GUN EVAPORATION APPARATUS AND FILM FORMATION METHOD USING THE ELECTRON GUN EVAPORATION APPARATUS 有权
标题翻译：电子喷雾装置的电子喷雾装置和膜形成方法
公开(公告)号：US20100247807A1
公开(公告)日：2010-09-30
申请号：US12438452
申请日：2008-01-29
申请人： Masato Nakayama
发明人： Masato Nakayama
IPC分类号： C23C14/28 , C23C14/00
CPC分类号： C23C14/30 , C23C14/544 , H01J37/304 , H01J37/3053 , H01J2237/30466 , H01J2237/30483 , H01J2237/3132
摘要： An electron gun evaporation apparatus capable of efficiently using an evaporation source includes an electron beam position controller which determines, as an applicable range, a range within which the distribution of the film thickness growth rate is almost constant in each scanning direction of an electron beam to be applied to an evaporation source in a crucible for the irradiation position of the electron beam, on the basis of information pertaining to the electron beam irradiation position and the film thickness growth rate in the electron beam irradiation position.
摘要翻译：能够有效地使用蒸发源的电子枪蒸发装置包括电子束位置控制器，该电子束位置控制器将电子束的每个扫描方向上的膜厚增长率的分布几乎恒定的范围确定为适用范围，基于与电子束照射位置和电子束照射位置的膜厚度生长速度有关的信息，施加到用于电子束的照射位置的坩埚中的蒸发源。

17. 发明授权

US07491492B2 Method of detecting nucleotide mutations 失效
标题翻译：检测核苷酸突变的方法
公开(公告)号：US07491492B2
公开(公告)日：2009-02-17
申请号：US10488312
申请日：2003-07-30
申请人： Masato Nakayama
发明人： Masato Nakayama
IPC分类号： C12Q1/68 , G01N33/566 , C07H21/02
CPC分类号： C12Q1/6827 , C12Q1/6858 , C12Q2565/519 , C12Q2533/107 , C12Q2525/301
摘要： The present invention provides a nucleotide mutation detection method wherein primers having a nucleotide sequence complementary to part of the nucleic acids to be detected and also having a nucleotide sequence, which is complementary to the nucleotide sequence just upstream from a nucleotide site corresponding to the mutation site of the nucleotide sequence formed at the 3′ end, added to the 5′ end, are produced so that so that the nucleotide site corresponding to the mutation site of the nucleic acids to be detected including the nucleotide mutation is located within the nucleotide sequence formed at the 3′ end after elongation; a target is produced by subjecting the primers to an elongation reaction using polymerase or Klenow enzyme; the target is then denatured to a single strand, and is subjected to a hybridization reaction with a probe that has the nucleotide complementary to the mutation site of the nucleic acids present in the 3′ end region and then to a ligation reaction, whereby it is enable to determine and assay a nucleotide located at a specific position in a nucleotide sequence of DNA or RNA and to analyze rapidly a variety of mutations including single nucleotide mutations, short nucleotide tandem repeat mutations, nucleotide deletion mutations, nucleotide insertion mutations, translocation mutations and so on.
摘要翻译：本发明提供了一种核苷酸突变检测方法，其中具有与要检测的核酸的一部分互补的核苷酸序列的引物，并且还具有核苷酸序列，该核苷酸序列与对应于突变位点的核苷酸位点刚好的核苷酸序列互补产生3'端形成的加入到5'末端的核苷酸序列，使得与包含核苷酸突变的待检测核酸的突变位点相对应的核苷酸位点位于形成的核苷酸序列内伸长后3'端; 通过使用聚合酶或Klenow酶对引物进行延伸反应来产生靶标; 然后将靶变性为单链，并与具有与存在于3'末端区域中的核酸的突变位点具有核苷酸互补性的探针进行杂交反应，然后进行连接反应，由此，能够确定和测定位于DNA或RNA核苷酸序列特定位置的核苷酸，并快速分析各种突变，包括单核苷酸突变，短核苷酸串联重复突变，核苷酸缺失突变，核苷酸插入突变，易位突变和所以。

18. 发明申请

US20080296098A1 Brake Shoe for Elevator Emergency Stop 审中-公开
标题翻译：电梯紧急停止制动鞋
公开(公告)号：US20080296098A1
公开(公告)日：2008-12-04
申请号：US12132647
申请日：2008-06-04
申请人： Goro Sato , Takahiko Sawada , Masato Nakayama , Takashi Teramoto , Koichi Miyata , Mitsugu Omori , Hidetaka Zama , Toshihiko Gotoh
发明人： Goro Sato , Takahiko Sawada , Masato Nakayama , Takashi Teramoto , Koichi Miyata , Mitsugu Omori , Hidetaka Zama , Toshihiko Gotoh
IPC分类号： B66B5/16
CPC分类号： B66B5/22
摘要： The present invention prevents cracking of a brake shoe even when the sliding surface of the brake shoe is heated to a high temperature and provides high reliability. The present invention provides a brake shoe for elevator emergency stop which generates a braking force by pressing brake shoes against a guide rail and making the brake shoes 5 slide to stop an elevator cage in the event of anomalies, including the brake shoes made of a cast iron material having a plurality of grooves 3 formed in a direction substantially perpendicular to the guide rail and gear teeth which constitute a sliding surface with the brake shoes 5 formed as gaps between the grooves, wherein the depth of the grooves is 3 mm or more and not more than 1.7 times the width of the gear teeth.
摘要翻译：本发明即使在制动瓦的滑动面被加热到高温并且提供高可靠性的情况下也能防止制动蹄的开裂。本发明提供一种用于电梯紧急停止的制动蹄，其通过将制动蹄压靠在导轨上而产生制动力，并且在异常情况下使制动蹄5滑动以停止电梯轿厢，包括由铸件制成的制动蹄铁材料具有形成在与引导轨道大致垂直的方向上的多个槽3和构成滑动面的齿轮齿，所述齿轮形成为槽之间的间隙，其中槽的深度为3mm以上，不超过齿轮齿宽度的1.7倍。

19. 发明授权

US07037934B2 Blood lipid ameliorant composition 失效
标题翻译：血脂改善剂组成
公开(公告)号：US07037934B2
公开(公告)日：2006-05-02
申请号：US10460535
申请日：2003-06-11
申请人： Tsuneki Ohsawa , Ikuo Takagi , Ippei Shimizu , Tatsuhito Kondo , Masato Nakayama , Yasuhiro Torizumi
发明人： Tsuneki Ohsawa , Ikuo Takagi , Ippei Shimizu , Tatsuhito Kondo , Masato Nakayama , Yasuhiro Torizumi
IPC分类号： A61K31/40 , A61K31/355 , A61K31/375 , A61K31/525 , A61K31/185
CPC分类号： A61K31/7076 , A61K31/185 , A61K31/355 , A61K31/375 , A61K31/401 , A61K31/525 , A61K2300/00
摘要： A blood lipid ameliorating composition containing atorvastatin in combination with an agent selected from the group consisting of a riboflavin derivative, a tocopherol compound, an ascorbic acid derivative, pantethine and taurine.
摘要翻译：一种含有阿托伐他汀与选自核黄素衍生物，生育酚化合物，抗坏血酸衍生物，泛尼精和牛磺酸的试剂组合的血脂改善组合物。

20. 发明申请

US20120080312A1 BIOMOLECULES DETECTION METHOD AND BIOMOLECULES DETECTION CHIP 审中-公开
标题翻译：生物分子检测方法和生物分子检测芯片
公开(公告)号：US20120080312A1
公开(公告)日：2012-04-05
申请号：US13323107
申请日：2011-12-12
申请人： Masato Nakayama
发明人： Masato Nakayama
IPC分类号： G01N27/327
CPC分类号： G01N27/3277 , B01L3/502715 , B01L7/52 , C12Q1/6825 , C12Q2537/101 , C12Q2563/113 , C12Q2565/607
摘要： A biomolecules detection chip which detects a detection target biomolecule by an electrochemical response measurement, the chip including: a chamber which is able to accommodate either a standard solution containing an electrochemically reactive agent having a binding capacity to the detection target biomolecule, or a sample solution containing a sample material and the electrochemically reactive agent; a liquid introduction device which introduces the standard solution or the sample solution into the chamber; an electrochemical response measurement device which measures an electrochemical response of either the standard solution or the sample solution accommodated in the chamber; and a liquid ejection device which ejects either the standard solution or the sample solution from the chamber.
摘要翻译：一种通过电化学响应测量来检测检测目标生物分子的生物分子检测芯片，该芯片包括：能够容纳包含具有与检测目标生物分子的结合能力的电化学反应剂的标准溶液的室或样品溶液含有样品材料和电化学反应剂; 将标准溶液或样品溶液引入室内的液体引入装置; 电化学响应测量装置，其测量容纳在腔室中的标准溶液或样品溶液的电化学响应; 以及从室排出标准溶液或样品溶液的液体喷射装置。

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